In this study, caudal anesthesia was performed with 0.25% bupivacaine and 0.25% bupivacaine-1% lidocaine mixtures at the end of operation. Anesthetics were administered randomly with the volume of 0.5 ml/kg, 0.75 ml/kg, 1.0 ml/kg and 1.25 ml/kg individually. The results were as following: 1) The more the volume of loeal anesthetics administered, the higher the spinal dermatome was blocked(P<0.005) and adequate analgesic levels were achieved. Body height classification by under and over 100 cm does not have statistically significant to determined of local anesthetic dosage. 2) Volume of local anesthetic solution required to block a spinal segment and body weight was most correlated to each other. At least 0.75 ml/kg or 1.0 ml/kg of local anesthetics are average amount for adequate pain control of pediatric urologic patients. 3) Only 17(24%) in 70 patients were required additive analgesic during postoperation 24 hours. 4) Local anesthetic volume required to block per a spinal segment was gradually increased with increased age and it markedly increased from 7 years old patients, this results have statistically significant correlationship. 5) The average volume of local anesthetic solution in patients under and over 100 cm in body height were 0.95+/-0.235 ml/spinal segment and 1.576+/-0.443 ml/spinal segment respectively(P< 0.0005). 6) Analgesic duration did not depend on operation site and body height(cm), analgesic duration tend to prolonged a little in patients who had undergone penoscrotal operation. 7) There was no statistical difference in analgesic durations between 0.25% bupivacaine group and 0.25% bupivacaine-1% lidocaine mixture group. With above results, we suggest that caudal analgesia in pediatric urologic patients who had undergone inguinal or penoscrotal operation would be simple, safe and effective method for postoperative pain relief.
Analgesia ; Anesthesia, Caudal* ; Anesthetics ; Anesthetics, Local ; Body Height ; Body Weight ; Bupivacaine ; Child ; Classification ; Humans ; Lidocaine ; Pain, Postoperative*

PURPOSE: Cardiovascular adverse events (AEs) after use of dipeptidyl peptidase-4 (DPP4) inhibitors have been reported and suspected since the launch of DPP-4 inhibitors in 2006. However, few studies have investigated the association between cardiovascular AEs and DPP-4 inhibitors. The objective of this study is to detect the signals of cardiovascular AEs after use of DPP-4 inhibitors by analyzing the Korea Institute of Drug Safety & Risk Management-Korea Adverse Event Reporting System Database (KIDS-KD). MATERIALS AND METHODS: Data on the use of oral antidiabetic drugs from 2008 to 2016 were extracted from KIDS-KD, and analyzed descriptively. Data mining was conducted by calculating three indices, which were proportional reporting ratios, reporting odds ratios, and information components, to detect signals from use of all oral antidiabetic drugs including DPP-4 inhibitors. Then, the suspected adverse drug reactions (ADRs) were confirmed by signal detection, and drug label information between the Korea Ministry of Food and Drug Safety and the U.S. Food and Drug Administration were compared. RESULTS: Cardiovascular AEs after taking DPP-4 inhibitors were detected in only three (1.0%) out of a total of 307 AE reports. Two of the three cardiovascular AEs were reported after using sitagliptin and one using gemiglipitin, but these were not statistically significant. CONCLUSION: Analysis of spontaneous ADR reports data on the use of DPP-4 inhibitors could not showed the association between DPP-4 inhibitors and cardiovascular AEs, due to a small number of cardiovascular AEs reports.
Cardiovascular Diseases ; Data Mining ; Drug-Related Side Effects and Adverse Reactions ; Hypoglycemic Agents ; Korea ; Odds Ratio ; Pharmacovigilance ; Sitagliptin Phosphate ; United States Food and Drug Administration

The plantaris muscle (PM) has a small fusiform muscle belly and a long slender tendon sandwiched between the soleus (SM) and gastrocnemius muscle (GM). During routine dissection for research, an additional PM in the popliteal region of a 75-year-old Korean female was discovered. Two distinct PMs were present, the superior PM (sPM) and inferior PM (iPM). While the sPM originates from the lower lateral supracondylar ridge and the knee capsule, the iPM originates from the femoral condyle and sPM tendon splitting into two parts at the distal belly. The lateral side of the iPM tendon travels between GM and SM and ends at the calcaneal tendon. sPM and the medial side of the iPM tendon run along with the sPM tendon and inserts at the fascia at the inner surface of proximal 1/3 of the medial head of GM. This case report introduces a new variation of the PM that should be taken into consideration.

The plantaris muscle (PM) has a small fusiform muscle belly and a long slender tendon sandwiched between the soleus (SM) and gastrocnemius muscle (GM). During routine dissection for research, an additional PM in the popliteal region of a 75-year-old Korean female was discovered. Two distinct PMs were present, the superior PM (sPM) and inferior PM (iPM). While the sPM originates from the lower lateral supracondylar ridge and the knee capsule, the iPM originates from the femoral condyle and sPM tendon splitting into two parts at the distal belly. The lateral side of the iPM tendon travels between GM and SM and ends at the calcaneal tendon. sPM and the medial side of the iPM tendon run along with the sPM tendon and inserts at the fascia at the inner surface of proximal 1/3 of the medial head of GM. This case report introduces a new variation of the PM that should be taken into consideration.

Because excessive consumption of sugar-sweetened beverages may reduce the quality of nutritional intake, this study examined the consumption patterns of commercial beverages, lifestyle, dietary habits, and perception of sweet taste. Participants were 407 male university students in Kyeonggido, Korea, and information was collected by self-administered questionnaire. Among them, 58 nonsmokers volunteered to participate in the taste test. Participants were divided into three groups according to the frequency of commercial beverage consumptions: 120 rare (< 1 serving/week), 227 moderate (1-3 servings/week) and 133 frequent (> 3 servings/week) consumption groups. More subjects from the rare consumption group chose water, tea, and soy milk, and more from the frequent consumption group chose carbonated soft drinks and coffee (P = 0.031) as their favorite drinks. Frequent consumption group consumed fruit juice, coffee, and sports and carbonated soft drinks significantly more often (P = 0.002, P = 0.000, P = 0.000, respectively), but not milk and tea. Frequent consumption group consumed beverages casually without a specific occasion (P = 0.000) than rare consumption group. Frequent drinking of commercial beverages was associated with frequent snacking (P = 0.002), meal skipping (P = 0.006), eating out (P = 0.003), eating delivered foods (P = 0.000), processed foods (P = 0.001), and sweets (P = 0.002), and drinking alcoholic beverages (P = 0.029). Frequent consumption group tended to have a higher threshold of sweet taste without reaching statistical significance. The results provide information for developing strategies for evidence-based nutrition education program focusing on reducing consumption of unnecessary sugar-sweetened commercial beverages.
Alcoholic Beverages ; Beverages ; Carbon ; Carbonated Beverages ; Coffee ; Drinking ; Eating ; Food Habits ; Fruit ; Humans ; Korea ; Life Style ; Male ; Meals ; Milk ; Surveys and Questionnaires ; Snacks ; Soy Milk ; Sports ; Tea ; Water

No abstract available.
Hearing Loss, Sensorineural* ; Immunoglobulin G*

OBJECTIVES: Among the Korean elderly (those 65 years of age and older), the suicide rate is 80.3/100 000 people, which is ten times higher than the Organization for Economic Cooperation and Development average. Because South Korea is rapidly becoming an aging population, this high elderly suicidal rate will only get worse. Although the size of the elderly suicide problem is quite large, previous research in South Korea has surveyed restricted areas and not the entire country. Even though the factors that affect elderly suicide are complicated, there has been little research into these influencing factors. Thus, this research uses the national survey data (Community Health Survey) that was obtained in 2009. Additionally, we analyze factors affecting elderly suicidal ideation and attempts as well as the paths of these effects. METHODS: Community Health Survey data obtained by the Korea Centers for Disease Control and Prevention in 2009 was used for this study. We additionally examined the factors that affect suicide with chi-squared tests, t-tests, Pearson's correlation test, and path analysis. RESULTS: Depressive symptoms and suicidal ideation are the only factors that directly affect suicidal attempts. Demographic, behavioral, and physical activity factors have indirect effects on suicidal attempts. CONCLUSIONS: Depression has the strongest influence on suicidal ideation and attempts. Demographic, behavioral, and physical activity factors affect suicidal attempts mostly through depressive symptoms. In addition, there is a path that suggests that demographic, behavioral, and physical activity factors affect suicidal attempts not through depression symptoms but only through suicidal ideation. This means that the elderly who do not have depression symptoms attempt suicide according to their own situations and characteristics.
Aged ; Databases, Factual ; Depression ; Factor Analysis, Statistical ; Female ; Health Behavior ; Humans ; Male ; Models, Theoretical ; Motor Activity ; Republic of Korea ; Risk Factors ; Suicidal Ideation ; Suicide, Attempted/psychology/*statistics & numerical data ; Surveys and Questionnaires

No abstract available.
Arthralgia* ; Hand*

Abstract: A 16-year-old cat presented with a 2-week history of anorexia and lethargy. Radiography revealed a soft-tissue opacity, heart-shaped mass between the descending colon and urinary bladder. Ultrasonography showed a large uterine body with a heterogeneously hypoechoic, thickened wall and hypoechoic intraluminal fluid. Computed tomography revealed a large, fluid-filled uterine mass with contrast enhancement, without evidence of regional lymph node or pulmonary metastasis. Ovariohysterectomy was performed and leiomyosarcoma was confirmed by histology. No notable abnormalities were observed during the 1-year postoperative follow-up periods. This report describes the diagnostic imaging and treatment of a rare case of feline uterine leiomyosarcoma.