PURPOSE: The purpose of this study was to identify the relationships between Moral Sensitivity, Empathy and Perceived Ethical Climate for nurses working in national mental hospitals and to provide basic data for the development of interventions that enhance Moral Sensitivity and help psychiatric hospital nurses in Ethical Decision-making. METHODS: This descriptive cross-sectional study was conducted with 182 psychiatric nurses working in the national mental hospitals. Data were collected through self-report questionnaires which included the Moral Sensitivity Questionnaire (MSQ), Interpersonal Reactivity Index (IRI), and Hospital Ethical Climate Survey (HECS). RESULTS: The mean score for MSQ was 5.19, for IRI, 2.49, and for HECS, 3.73. There was a significant positive correlation between moral sensitivity and empathy (r=.24, p=.001), between moral sensitivity and perceived ethical climate (r=.17, p= .025) and between empathy and perceived ethical climate (r=.17, p=.025). CONCLUSION: Findings indicate that moral sensitivity can be enhanced by improving empathy, a personal factor, and ethical climate, an organization factor. Further identification of the relationship between moral sensitivity and personal and organizational factors will be useful in the development of interventions to enhance moral sensitivity of nurses working in psychiatric wards.
Climate* ; Cross-Sectional Studies ; Empathy* ; Hospitals, Psychiatric* ; Humans

PURPOSE: The purpose of this study was to investigate the level of traumatic experiences, posttraumatic stress symptoms and mental health-related characteristics in young adults and identify relationships among the variables. METHODS: In this descriptive cross-sectional study, data were collected through a Web-based survey (N=568). Structured instruments included valid measures of traumatic experiences, posttraumatic stress symptoms, depression, somatization symptoms, insomnia, and alcohol use. Collected data were analyzed using descriptive statistics, t-tests, χ2 tests, ANOVA, and Pearson correlation coefficient with SPSS statistics 23. RESULTS: Among study participants, 76.8% reported traumatic experiences. The severity of trauma was associated with high levels of posttraumatic stress symptoms, depression, somatization symptoms, insomnia, and alcohol use. Women showed more severe posttraumatic stress and depressive symptoms than men. There were positive correlations for trauma experiences with posttraumatic stress symptoms, depression, somatization symptoms, and insomnia. CONCLUSION: Findings indicate the need to develop nursing intervention programs to relieve posttraumatic stress symptoms and improve mental health related characteristics targeting young adults, and to establish a national policy that addresses characteristics of trauma experienced in Korea.
Cross-Sectional Studies ; Depression ; Female ; Humans ; Korea ; Male ; Mental Health ; Nursing ; Sleep Initiation and Maintenance Disorders ; Stress Disorders, Post-Traumatic ; Young Adult

Human health problems due to long life are becoming major issues in society, and in particular greater interest collected on women's health after menopause. Many substances can be introduced to women's health, however, materials from the substances have not shown all of the safety and efficacy properties that are not easily found. Currently, it is known about the effects of the disease on the female insect-derived material that is capable of overcoming this problem significantly. When using the insect-derived material through the results of several studies suggest that it is possible to solve a hormonal imbalance and nutritional imbalance in the elderly. Here, we'd like to try to dissertate about the new trends for women's health improvement using novel materials-derived from insects.
Aged ; Female ; Humans ; Insects ; Menopause* ; Nutritional Status ; Women's Health*

Ovarian cancer is a leading cause of death in women. Early detection of ovarian cancer is essential to decrease mortality. However, the early diagnosis of ovarian cancer is difficult due to a lack of clinical symptoms and suitable molecular diagnostic markers. Thus, identification of meaningful tumor biomarkers with potential clinical application is clearly needed. To search for a biomarker for the early detection of ovarian cancer, we identified human anterior gradient 2 (AGR2) from our systematic analysis of paired normal and ovarian tumor tissue cDNA microarray. We noted a marked overexpression of AGR2 mRNA and protein in early stage mucinous ovarian tumors compared to normal ovarian tissues and serous type ovarian tumors by Western blot analysis and immunohistochemistry. To further elucidate the role of AGR2 in ovarian tumorigenesis, stable 2774 human ovarian cancer cell lines overexpressing AGR2 were established. Forced expression of AGR2 in 2774 cells enhanced the growth and migration of ovarian cancer cells. AGR2 protein was detected in the serum of mucinous ovarian cancer patients by Western blot and ELISA analysis. Thus, AGR2 is a potential biomarker for the diagnosis of mucinous ovarian cancer and an ELISA assay may facilitate the early detection of mucinous ovarian cancer using patient serum.
Cell Line, Tumor ; Cell Movement/physiology ; Cell Proliferation ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Ovarian Neoplasms/genetics/*metabolism/pathology ; Proteins/genetics/*metabolism ; Tumor Markers, Biological/blood/*metabolism