1.Long-term survival after intraperitoneal chemotherapy with paclitaxel-cisplatin for recurrent primary peritoneal cancer resistant to multiple lines of intravenous chemotherapy
Hyejeong HUE ; Kidong KIM ; HyoJin KIM ; Dong Hoon SUH ; Jae Hong NO ; Yong Beom KIM
Obstetrics & Gynecology Science 2019;62(4):285-289
The long-term survival of heavily pretreated patients with primary peritoneal cancer (PPC) is uncommon. Here, we report on a patient with PPC refractory to multiple lines of intravenous chemotherapy, namely, a combined regimen of paclitaxel and carboplatin, and single regimens of topotecan, docetaxel, cisplatin, and gemcitabine. However, after intraperitoneal (IP) chemotherapy with paclitaxel-cisplatin, the patient's condition improved, and she has been progression-free for more than 4 years. Interestingly, before the IP chemotherapy, the recurrences were limited to the peritoneal cavity. These results suggest that IP recurrence might be a predictor of a good response to IP chemotherapy.
Carboplatin
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Cisplatin
;
Drug Therapy
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Humans
;
Infusions, Parenteral
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Neoplasm Recurrence, Local
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Ovarian Neoplasms
;
Paclitaxel
;
Peritoneal Cavity
;
Peritoneal Neoplasms
;
Recurrence
;
Topotecan