1.Association between green tea consumption and metabolic syndrome among Korean adults: results from the Health Examinees study
Hyeonjin CHO ; Sunwoo HAN ; Jiwon JEONG ; Hyein JUNG ; Sangah SHIN
Journal of Nutrition and Health 2023;56(1):70-85
Purpose:
Several studies have been conducted on the relationship between green tea intake and metabolic syndrome. However, compared to the studies carried out internationally, there is inadequate research on the relationship between domestic green tea consumption and metabolic syndrome. Therefore, in this study, the general characteristics of Koreans according to their green tea intake and its association with metabolic syndrome were examined.
Methods:
A total of 44,611 subjects were included in the study, and analysis was carried out using data from the Korean Genome and Epidemiology Study (KoGES) for Korean adults aged 40 or older. Green tea consumption was estimated using 106 verified food frequency questionnaires (FFQ). Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) parameters. After adjusting for confounding variables by performing a Cox regression analysis, the association between green tea consumption and metabolic syndrome was confirmed through the hazard ratio (HR) and 95% confidence interval (CI).
Results:
The average incidence of metabolic syndrome was 18.7% (20.8% in men and 17.8% in women). Compared to those who drank almost no green tea, in subject groups consuming more than one cup of green tea a day, the metabolic syndrome incidence was significantly reduced by 15% (HR, 0.85; 95% CI, 0.74–0.96; p trend = 0.0200) among men and by 19% (HR, 0.81; 95% CI, 0.73–0.90; p trend < 0.0001) among women. In addition, the biomarkers related to metabolic syndrome also tended to decrease overall in these groups.
Conclusion
This study concluded that as the intake of green tea increased, the incidence of metabolic syndrome and related indicators decreased. Therefore, green tea intake is believed to have a positive effect on the prevention and management of the metabolic syndrome.
2.Application and effectiveness of a nutrition education program based on the 2020 Dietary Reference Intakes for Koreans for undergraduates in Gyeongsangnam-do and Gyeonggi-do
Mijoo CHOI ; Hyein JUNG ; Nayoung KIM ; Sangah SHIN ; Taejung WOO ; Eunju PARK
Journal of Nutrition and Health 2023;56(6):730-741
Purpose:
The 2020 Dietary Reference Intakes for Koreans (KDRIs) serves as a foundation for daily nutrient and energy recommendations aiming to enhance public health and prevent chronic diseases. They act as guidelines for maintaining proper nutrition and overall health.Using KDRIs is crucial for promoting healthier lifestyles and making informed dietary choices. Thus, this study explores the influence of a nutrition education program, based on the 2020 KDRIs, on the nutrition knowledge and dietary habits of undergraduates in Gyeongsangnam-do and Gyeonggi-do.
Methods:
The nutrition education program, designed with diverse instructional materials, was executed across a wide range of universities. The education group (n = 75) engaged in the program for a 6-week instructional period, while the control group (n = 53) underwent the survey without participating in the education program. Nutrition Quotient (NQ) and knowledge assessments were administered to both groups immediately before and after the instructional period.
Results:
Within the education group, the nutrition education program positively impacted responses to NQ practice items, including knowledge of nutrition, daily intake, and portion sizes (p < 0.05). In contrast, there were no significant differences between the before and after responses of the control group for most survey items. Post-program evaluations showed significantly higher self-assessment scores and increased satisfaction levels (p < 0.05), with the satisfaction rate for the education program using the 2020 KDRIs reaching 99.2%.
Conclusion
This study has demonstrated the positive impact of an effective nutrition education program. However, there is a need for the continuous development and implementation of nutrition education programs to sustain these outcomes and further enhance the nutritional education experience.
3.First Case of Cellular Cannibalism in Small-Cell Carcinoma of the Bladder Detected in Peripheral Blood
Hyein KANG ; Do Hoon KIM ; Wonmok LEE ; Jungsook HA ; Namhee RYOO ; Dong Seok JEON ; Hye Ra JUNG
Annals of Laboratory Medicine 2019;39(4):400-402
No abstract available.
Cannibalism
;
Urinary Bladder
4.Osteosarcomatous Differentiation in Rebiopsy Specimens of Pulmonary Adenocarcinoma with EGFR-TKI Resistance
Hyein AHN ; Hyun Jung KWON ; Eunhyang PARK ; Hyojin KIM ; Jin Haeng CHUNG
Journal of Pathology and Translational Medicine 2018;52(2):130-132
No abstract available.
Adenocarcinoma
5.Development of a novel nomogram for predicting ongoing pregnancy after in vitro fertilization and embryo transfer.
Seul Ki KIM ; Hyein KIM ; Soohyun OH ; Jung Ryeol LEE ; Byung Chul JEE ; Seok Hyun KIM
Obstetrics & Gynecology Science 2018;61(6):669-674
OBJECTIVE: This study aimed to develop a nomogram that predicts ongoing pregnancy after in vitro fertilization and embryo transfer (IVF-ET) using patient age and serum hormonal markers. METHODS: A total of 284 IVF-ET cycles were retrospectively analyzed. At 14 days post-oocyte pick-up (OPU), the serum human chorionic gonadotropin (HCG) and progesterone levels were measured. The main predicted outcome was ongoing pregnancy. RESULTS: Patient age and serum of HCG and progesterone levels at 14 days post-OPU were good predictors of ongoing pregnancy. The cut-off value and area under the curve (AUC) (95% confidence interval) were 36.5 years and 0.666 (0.599–0.733), respectively, for patient age; 67.8 mIU/mL and 0.969 (0.951–0.987), respectively, for serum HCG level; and 29.8 ng/mL and 0.883 (0.840–0.925), respectively, for serum progesterone level. When the prediction model was constructed using these three parameters, the addition of serum progesterone level to the prediction model did not increase its overall predictability. Furthermore, a high linear co-relationship was found between serum HCG and progesterone levels. Therefore, we developed a new nomogram using patient age and HCG serum level only. The AUC of the newly developed nomogram for predicting ongoing pregnancy after IVF-ET cycles using patient age and serum HCG level was as high as 0.975. CONCLUSION: We showed that ongoing pregnancy may be predicted using only patient age and HCG serum level. Our nomogram could help clinicians and patients predict ongoing pregnancy after IVF-ET if the serum JCG level was ≥5 IU/L at 14 days post-OPU.
Area Under Curve
;
Chorionic Gonadotropin
;
Embryo Transfer*
;
Embryonic Structures*
;
Fertilization in Vitro*
;
Humans
;
In Vitro Techniques*
;
Nomograms*
;
Pregnancy*
;
Progesterone
;
Retrospective Studies
6.Correlation Between C3d Assay and Single Antigen Bead Assay for Detection of Human Leukocyte Antigen Class II Antibodies
Hyein KANG ; Do-Hoon KIM ; Jung Sook HA ; Namhee RYOO ; Dong-Seok JEON ; Wonmok LEE
Laboratory Medicine Online 2020;10(4):295-300
Background:
Detection of anti-human leukocyte antigen (HLA) antibodies is important during the selection of an appropriate donor prior to organ transplantation and also for monitoring the patients after transplantation. In this study, we compared antibodies detected via C3d assays, which monitors C3d complement-binding activities of HLA antibodies with those detected via single antigen bead (SAB) assays.
Methods:
A total of 66 serum samples were tested in parallel by SAB assays (Immucor Transplant Diagnostics, USA) and C3d assays (Immucor) for the detection of HLA class II antibodies. The relationship between these two methods was analyzed based on the types, numbers, median fluorescent intensity (MFI) values, and positivity of the antibodies using MATCH IT! Antibody (Immucor) program.
Results:
The number of antibodies obtained based on SAB and C3d assays was the highest with 24 samples (36.4%) in the 11–20 range and 23 (34.8%) in the 2–5 range detected via each assay. Among the SAB-positive antibodies, only 28 (6.4%) of the 440 antibodies with MFI ≤3,000 were C3d-positive, and 341 (61.3%) of the 556 antibodies with MFI ≥3,001 were C3d-positive. Whereas, among the 442 C3d-positive antibodies, SAB assays were positive except for 32 (7.2%) and 41 (9.3%) antibodies in the sections of MFI ≤500 and 1,001 ≤MFI ≤10,000, respectively. C3d-positive samples had higher maximum MFI values based on SAB assays, compared with C3d-negative samples.
Conclusions
MFI values of HLA class II antibodies detected through SAB assays in C3d-positive samples were higher than those in C3d-negative samples.
7.Correlation Between C3d Assay and Single Antigen Bead Assay for Detection of Human Leukocyte Antigen Class II Antibodies
Hyein KANG ; Do-Hoon KIM ; Jung Sook HA ; Namhee RYOO ; Dong-Seok JEON ; Wonmok LEE
Laboratory Medicine Online 2020;10(4):295-300
Background:
Detection of anti-human leukocyte antigen (HLA) antibodies is important during the selection of an appropriate donor prior to organ transplantation and also for monitoring the patients after transplantation. In this study, we compared antibodies detected via C3d assays, which monitors C3d complement-binding activities of HLA antibodies with those detected via single antigen bead (SAB) assays.
Methods:
A total of 66 serum samples were tested in parallel by SAB assays (Immucor Transplant Diagnostics, USA) and C3d assays (Immucor) for the detection of HLA class II antibodies. The relationship between these two methods was analyzed based on the types, numbers, median fluorescent intensity (MFI) values, and positivity of the antibodies using MATCH IT! Antibody (Immucor) program.
Results:
The number of antibodies obtained based on SAB and C3d assays was the highest with 24 samples (36.4%) in the 11–20 range and 23 (34.8%) in the 2–5 range detected via each assay. Among the SAB-positive antibodies, only 28 (6.4%) of the 440 antibodies with MFI ≤3,000 were C3d-positive, and 341 (61.3%) of the 556 antibodies with MFI ≥3,001 were C3d-positive. Whereas, among the 442 C3d-positive antibodies, SAB assays were positive except for 32 (7.2%) and 41 (9.3%) antibodies in the sections of MFI ≤500 and 1,001 ≤MFI ≤10,000, respectively. C3d-positive samples had higher maximum MFI values based on SAB assays, compared with C3d-negative samples.
Conclusions
MFI values of HLA class II antibodies detected through SAB assays in C3d-positive samples were higher than those in C3d-negative samples.
8.Association of hypertension with noodle consumption among Korean adults based on the Health Examinees (HEXA) study
Suji CHOI ; Jungmin PARK ; Hyein JUNG ; Jiwon JEONG ; Kyungjoon LIM ; Sangah SHIN
Nutrition Research and Practice 2024;18(2):282-293
BACKGROUND/OBJECTIVES:
The prevalence of hypertension is increasing, and noodles have a high sodium content, so noodle consumption might be associated with a higher prevalence of hypertension. This study aimed to analyze the association between total and types of noodle intake and the risk of hypertension among Korean adults. Subjects aged 40–69 years were selected for this study.
SUBJECTS/METHODS:
This study included 56,580 participants (18,246 men and 38,334 women) aged 40–69 years old from the Health Examinees study. Noodle and nutrient intakes were assessed using the food frequency questionnaire. Hypertension was diagnosed as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg or antihypertensive medication use. Cox proportional hazard models were used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for hypertension.
RESULTS:
Higher noodle consumption was associated with increased hypertension among men (HR, 1.273; 95% CI, 1.166–1.390) and women (HR, 1.116; 95% CI, 1.038–1.199).
CONCLUSION
We recommended reducing noodle intake and consuming vegetables and fruits to increase potassium intake, which can prevent vascular diseases.
9.Association of hypertension with noodle consumption among Korean adults based on the Health Examinees (HEXA) study
Suji CHOI ; Jungmin PARK ; Hyein JUNG ; Jiwon JEONG ; Kyungjoon LIM ; Sangah SHIN
Nutrition Research and Practice 2024;18(2):282-293
BACKGROUND/OBJECTIVES:
The prevalence of hypertension is increasing, and noodles have a high sodium content, so noodle consumption might be associated with a higher prevalence of hypertension. This study aimed to analyze the association between total and types of noodle intake and the risk of hypertension among Korean adults. Subjects aged 40–69 years were selected for this study.
SUBJECTS/METHODS:
This study included 56,580 participants (18,246 men and 38,334 women) aged 40–69 years old from the Health Examinees study. Noodle and nutrient intakes were assessed using the food frequency questionnaire. Hypertension was diagnosed as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg or antihypertensive medication use. Cox proportional hazard models were used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for hypertension.
RESULTS:
Higher noodle consumption was associated with increased hypertension among men (HR, 1.273; 95% CI, 1.166–1.390) and women (HR, 1.116; 95% CI, 1.038–1.199).
CONCLUSION
We recommended reducing noodle intake and consuming vegetables and fruits to increase potassium intake, which can prevent vascular diseases.
10.Association of hypertension with noodle consumption among Korean adults based on the Health Examinees (HEXA) study
Suji CHOI ; Jungmin PARK ; Hyein JUNG ; Jiwon JEONG ; Kyungjoon LIM ; Sangah SHIN
Nutrition Research and Practice 2024;18(2):282-293
BACKGROUND/OBJECTIVES:
The prevalence of hypertension is increasing, and noodles have a high sodium content, so noodle consumption might be associated with a higher prevalence of hypertension. This study aimed to analyze the association between total and types of noodle intake and the risk of hypertension among Korean adults. Subjects aged 40–69 years were selected for this study.
SUBJECTS/METHODS:
This study included 56,580 participants (18,246 men and 38,334 women) aged 40–69 years old from the Health Examinees study. Noodle and nutrient intakes were assessed using the food frequency questionnaire. Hypertension was diagnosed as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg or antihypertensive medication use. Cox proportional hazard models were used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for hypertension.
RESULTS:
Higher noodle consumption was associated with increased hypertension among men (HR, 1.273; 95% CI, 1.166–1.390) and women (HR, 1.116; 95% CI, 1.038–1.199).
CONCLUSION
We recommended reducing noodle intake and consuming vegetables and fruits to increase potassium intake, which can prevent vascular diseases.