In 1962, Durand suggested the term primary lactose intolerance for the disorder withch resulted from a defect of the lactase activity in the intestinal mucosa. However primary lactose intolerance is rare and it is not commonly encountered in routine pediatric practice. Apart from such a primary lactose intolerance, diarrhea, meteorism, and abdominal discomfort after taking lacose containing food are more frequently encoumtered in case of gastroenteritis in which damage of the intestinal mucosa and coating of the mucosa by inflammatory secretions lead to decreased lactase it form the primary lactose intolerance. It is now considered that secondary lactose intolerance may play an important role in case of infantile diarrhea commonly encoutered in pediatric practice. The auther tried the lactase preparation Galantase?to evaluated it's clinical effect on infantile diarrhea of various kind (50 cases). Evaluation of the effect of Galantase was made on the bases of the following criteria. l Marked effective ; nature of stools and number per day returned to normal within 3 days after Galantase administration. l Effective ; nature of stools and number per day decreased within 3 days after Galantase administration. l Ineffective ; all stools remained unchainged and diarrheic. The results obtsined by this study are as followes l Marked effective ; 78 % l Effective ; 12 % l Slight effective ; 4% l Ineffective ; 6% There was no undesirable side effect observed in all 50 cases. Based upon the above effective rate, we concluded that the Galantase is a quite effective medicament for infantile diarrhea, especially for primary and secondary lactose intolerance.
Diarrhea ; Diarrhea, Infantile* ; Gastroenteritis ; Infant ; Intestinal Mucosa ; Lactase ; Lactose Intolerance ; Meteoroids ; Mucous Membrane

The authors observed 190 cases of intussusception who were admitted to the Department of Pediatrics of Hanyang University Hospital from May, 1972 to August, 1977. And we had clinical analysis of these patients with a review of literatures. The results of clinical analysis of these patients were summarized as following. 1. In age distribution, 86.3% of the these patients were summarized as following. 2. Sex ratio of male to female was about 2:1 3. In seasonal distribuution, there were prevalent in Spring. 4. 75.9% of them were over 50 percentiles of development standard of Korean nomal infants and children by body weight. 5. The etiologic causes were found only in 1.7% of them and the other were idiopathic. 6. The most common anatomical type was ileo-colic type (77.4%) 7. The cardinal symptoms and signs were vomiting (82.1%), abdominal pain(81.6%), mucous bloody stool(67.9%), and palpable abdominal mass(62.1%), in order. 8. The reduction rate with barium enema was 78.2% and was high in the following cases ; (1) early visiting to the hospital, and (2) ileo-colic and colo-colic in type. 9. The rate of complication after surgery was 2.1% of all observed cases and mortality rate was 1.05%. The recurrence after first reduction occurred in 8.95% of all.
Age Distribution ; Barium ; Body Weight ; Child* ; Enema ; Female ; Humans ; Infant ; Intussusception* ; Male ; Mortality ; Pediatrics ; Recurrence ; Seasons ; Sex Ratio ; Vomiting