1.Corrigendum: Qualitative Analysis of Tele-healthcare Systems based on the Diffusion of Innovation Model.
Myung Soon KWON ; Ghee Young NOH ; Ji Hye JANG
Journal of Korean Academy of Community Health Nursing 2017;28(3):357-357
This erratum is being published to correct the co-authors errors.
2.Cinical Significance of Visceral Adipose Tissue.
Journal of the Korean Academy of Family Medicine 2007;28(10):739-747
No abstract available.
Intra-Abdominal Fat*
3.A Case of Multiple Brain Abscess Complicated to Purulent Meningitis in Newborn.
Kui Ja KIM ; Hye Young CHUNG ; Tae Chan KWON ; Young Dae KWON ; Chin Moo KANG
Journal of the Korean Pediatric Society 1983;26(7):717-721
No abstract available.
Brain Abscess*
;
Humans
;
Infant, Newborn*
;
Meningitis*
5.Two cases of Edward syndrome.
Jin Bok HWANG ; Woo Hyun KWON ; Soon Young SONG ; Chang Ho HAN ; Hye Li CHUNG ; Young Dae KWON
Journal of the Korean Pediatric Society 1991;34(2):250-255
No abstract available.
6.Human Studies on Functional Foods: How They Are Regulated.
Joohee KIM ; Ji Yeon KIM ; Hye Suk WON ; Hye Jin KWON ; Hye Young KWON ; Hye In JEONG ; Oran KWON
The Korean Journal of Nutrition 2010;43(6):653-660
Along with the steady growth of health functional food (HFF) markets, research evaluating the human effects of HFF has been expanding. In this study, we investigated the regulatory and management system of human study on HFF in the USA, Japan and UK, and the Korean domestic regulations on HHF, medicines, medical devices, cosmetics and biotechnology in order to improve the domestic management system. In these four countries, institutional review board (IRB) or research ethics committee (REC) approvals are required for on human study of HHF, but regulatory and management systems differ from country to country. In the USA, human studies on HFF for structure/function claims do not require the FDA's prior approval but clinical trials of the disease treatment effects of HHF require prior approval from the FDA. In the USA, IRBs are managed by the Department of Health and Human Services (DHHS) rather than the FDA, and IRBs in those institutions which would execute the clinical trials requiring prior approval from the FDA or human studies funded by the USA federal government are required to be registered on the DHHS. In the UK, although the government does not require prior approval of human study, authorized RECs managed by the National Research Ethics Service (NRES) and other independent RECs review the human study. In Japan, human study for HFF must conform with "Ethical guidelines for epidemiological research" and IRB registration has not been required. In Korean domestic regulations, the responsibilities, compositions, functions and operations of IRBs on medicines, medical devices and biotechnology are legally specified, but not those of IRB on HHF. These foreign statuses for the management of human study on HFF and comparisons with Korean regulations are expected to be used as basic data to improve the domestic legal system.
Biotechnology
;
Cosmetics
;
Ethics Committees, Research
;
Ethics, Research
;
Federal Government
;
Financial Management
;
Functional Food
;
Humans
;
Japan
;
Social Control, Formal
;
United States Dept. of Health and Human Services
7.A Case of Athetosis in Basal Ganglia Calcification Associated with Hypoparathyroidism.
Yoo Mi PARK ; Hye Young KWON ; Hoo Won KIM ; Dong Kwon KIM
Journal of the Korean Neurological Association 1995;13(4):1017-1019
Extrapyramidal tract motor disorder in calcification of basal ganglia probably occurs when the deposition of acid mucopolysaccharides in the basal ganglia is severe enough to lead to neuronal loss. Basal ganglia calcification has been noted to occur with higher incidence and intensity in encephalitis lethargica, carbon monocide intoxication, anoxia, tuberous sclerosis, toxoplasmosis, hypothyroidism and hypoparathyroidism. The neurologic disorder is frequently reversible with treatment in patients with basal ganglia calcification who have hypoparathy-roidism. We report a patient with idiopathic hypoparathyroidism associated with bilateral calcification of the basal ganglia and athetoid movement. This is the first case report in Korea.
Anoxia
;
Athetosis*
;
Basal Ganglia*
;
Carbon
;
Cefonicid
;
Encephalitis
;
Extrapyramidal Tracts
;
Glycosaminoglycans
;
Humans
;
Hypoparathyroidism*
;
Hypothyroidism
;
Incidence
;
Korea
;
Nervous System Diseases
;
Neurons
;
Toxoplasmosis
;
Tuberous Sclerosis
8.A Case of Diffuse Leukoencephalopathy Caused by 5-Fluorouracil.
Yoo Mi PARK ; Hye Young KWON ; Hoo Won KIM ; Dong Kwon KIM
Journal of the Korean Neurological Association 1995;13(4):1007-1010
5-Fluorouracil is one of the most commonly used anticancer drug. We report a case of leukoencephalopathy who had received 5-fluorouracil injection following operation of carcinoid tumor in intestine. The case had dementia, dysarthria and gait disturbance. Brain CT showed bilaterally symmetric diffuse low densities in the white matter of cerebrum and cytologic examination of cerebrospinal fluid was negative for malignancy. Discontinuation of 5- fluorouracil injection for several days and then improved the clinical symptoms.
Brain
;
Carcinoid Tumor
;
Cerebrospinal Fluid
;
Cerebrum
;
Dementia
;
Dysarthria
;
Fluorouracil*
;
Gait
;
Intestines
;
Leukoencephalopathies*
9.Outcome and Prognosis in Patients Receiving Continuous Renal Replacement Therapy.
Seung Ho LEE ; Soon Kil KWON ; Hye Young KIM
Korean Journal of Nephrology 2010;29(4):434-440
PURPOSE: Acute kidney injury is a critical complication in patients intensive care unit (ICU) and shows high mortality. After development of continuous renal replacement therapy (CRRT), there were many conflicting data for patient survival. We want to find out which parameter shows strong correlation in the survival of patients undergoing CRRT in intensive care unit. METHODS: Total 85 patients were enrolled who had been treated with CRRT in ICU. We compared the differences in clinical parameters between survivors with non-survivors. RESULTS: Mean age of the patients was 62.0+/-15.6 and 57 patients were male (67.1%). Out of 85 patients, 39 patients survived (45.9%). Mean duration of CRRT was 103.5+/-178.8 hours and mean Acute Physiology And Chronic Health Evaluation (APACHE) III score was 90.6+/-22.6. There were significant differences between survivors and non-survivors in APACHE III score (p=0.004), time to initiation of CRRT (p=0.05), systolic blood pressure at initiation of CRRT (p=0.001), arterial [H+] (50.18 vs. 84.19, p=0.001), respectively. But there was no difference in the age, sex, the level of pre CRRT blood urea nitrogen, duration of ICU admission, hypoxemia and hemoglobin level. CONCLUSION: Earlier initiation of CRRT and protection from metabolic acidosis were strongly associated with the survival of the patient with acute kidney injury in ICU.
Acidosis
;
Acute Kidney Injury
;
Anoxia
;
APACHE
;
Blood Pressure
;
Blood Urea Nitrogen
;
Hemodiafiltration
;
Hemoglobins
;
Humans
;
Intensive Care Units
;
Male
;
Prognosis
;
Renal Replacement Therapy
;
Survivors
10.A Case of Caverneous Lymphangioma.
Yang Won LEE ; Oh Kyun KWON ; Hye Suk HONG ; YOung Hun CHUNG
Journal of the Korean Pediatric Society 1987;30(2):229-233
No abstract available.
Lymphangioma*