1.A study on patterns of menstruation and age of menarche of urban middle school girls.
Young Soon JANG ; Hye Soon PARK ; Hong Jun CHO ; Young Sik KIM
Journal of the Korean Academy of Family Medicine 1991;12(10):66-73
No abstract available.
Female
;
Female*
;
Humans
;
Menarche*
;
Menstruation*
2.Benign occipital spikes.
Joon Soo LEE ; Hye Young KANG ; Chang Jun COE ; Young Hyuk LEE
Journal of the Korean Child Neurology Society 1993;1(1):83-89
No abstract available.
3.Spindle and Epithelioid Cell Nevus: Report of four cases.
Hye Ju AN ; Kyo Young LEE ; Sang In SHIM ; Sun Moo KIM ; Jun Young LEE ; Baik Kee CHO
Korean Journal of Pathology 1987;21(4):317-322
The spindle and epithelioid cell nevus, is known also as Spitz's nevus or benign juvenile melanoma. The histologic picture of the lesion often closely resembles that of a malignant melanoma, but spindle and epithelioid cell nevus hehaves benignly. Criteria for accurate histological diagnosis of this nevus now exist. However, a difficult lesion occasionally brings one to the worrisome situation even now. We experienced four cases (three children and one adult) of spindle and epithelioid cell neveus with nodular or macular skin lesions. In children (7/F, 9/F, 4/M), all of the lesion show a solitary pinkish red or light brown nodular firm masses, 0.7 cm to 1.0 cm in greatest dimension, which are located at the left posterior thigh, posterior neck and right anterior neck region, respectively. In adult (36/F), the lesion shows a light brown, erythematous macule, 0.8 cm in greatest diameter, in the skin of the back. Microscopically, both spindle and epithelioid cells are found in all the four cases, but epithelioid cells predominate in children and spindle cells predominate in adult.
Child
;
Adult
;
Male
;
Female
;
Humans
4.Ectopic Paragonimiasis Presented as Multiple Colonic and Liver Masses.
Hye Sung KIM ; Young Soo LEE ; Yun Kyung KANG ; Hye Kyung LEE ; Jun Hee KIM ; Hyuk Sang LEE
Korean Journal of Pathology 1997;31(4):357-360
Ectopic paragonimiasis has been diagnosed in many organs such as the mesentery, ovary, pleura, central nervous system, subcutis and very rarely in the liver. However, simultaneous involvement of the colon and liver, which mimics colonic cancer with liver metastasis, is quite unusual, and to our knowledge has never been reported. Our case is a 63 year old woman who visited our hospital because of upper abdominal pain. Radiologically, space occupying lesions were detected in the transverse colon, mesocolon and left hepatic lobe. After the radical presection, they were proved to be an ectopic paragonimiasis forming multiple cavitary parasitic granulomas with Charcot-Leyden crystals and degenerating eggs.
Abdominal Pain
;
Central Nervous System
;
Colon*
;
Colon, Transverse
;
Colonic Neoplasms
;
Eggs
;
Female
;
Granuloma
;
Humans
;
Liver*
;
Mesentery
;
Mesocolon
;
Middle Aged
;
Neoplasm Metastasis
;
Ovary
;
Ovum
;
Paragonimiasis*
;
Pleura
5.Cervical tuberculous lymphadenitis : Clinicopathological reatures and AFB positivity.
Young Jun HWANG ; Mi Hye KO ; Se Young YUN ; Yong Ho KIM ; Doh Hyung KIM ; Kye Young LEE ; Keun Youl KIM ; Na Hye MYONG ; Jae Seuk PARK
Tuberculosis and Respiratory Diseases 2000;48(5):720-729
BACKGROUND: Histological analysis of tuberculosis shows a spectrum of findings, from well formed granulmatous inflammation with few bacilli in patient with normal immune response to M. tuberculosis to poorly formed granulomatous inflammation with many bacilli in patient with defective immune response. To evaluate the degree of immune response to M. tuberculosis, we studied the histologic features, including the presence of acid fast bacilli(AFB) in lymph node of patients with cervical tuberculous lymphadenitis, and compared them with clinical characteristics. METHODS: We reviewed the histologic features of 33 cases of cervical tuberculous lymphadenitis and processed the excised nodes for auramine-rhodamine staining to detect AFB. The AFB positivity in tissue was compared with the histologic features(degree of granuloma formation, presence of caseation necrosis, presence of neutrophilic infiltration) and clinical characteristics (lymph node size, duration of symptom, presence of local symptom or radiologic evidence of pulmonary tuberculosis). RESULTS: 1) The mean age at diagnosis was 42.4 years, and male to female ratio was 1 : 45. 2) Histologically, all cases showed well formed granuloma and variable degrees of caseation necrosis, and 39% of the cases showed neutrophilic infiltration in the granulomatous inflammation. 3) AFB were confirmed in 52% of the cases, and they were found extracellularly and at the periphery of caseation necrosis. 4) There was no association between AFB Positivity and histological features or clinical characteristics. CONCLUSION: Cervical tuberculous lymphadenitis showed well formed granulomatous inflammation with caseation necrosis, and there was no association between AFB positivity in the tissue and histological or clinical characteristics.
Diagnosis
;
Female
;
Granuloma
;
Humans
;
Inflammation
;
Lymph Nodes
;
Lymphadenitis
;
Male
;
Necrosis
;
Neutrophils
;
Tuberculosis
;
Tuberculosis, Lymph Node*
6.A Case of Mantle Cell Lymphoma with Skin Metastasis.
Hye Young JU ; Hye Seung KIM ; Jun Young LEE ; Hyung Ok KIM ; Young Min PARK
Korean Journal of Dermatology 2010;48(2):158-160
Mantle cell lymphoma is a malignant lymphoma derived from a subset of B-cells that are localized in the mantle area of the lymphoid follicle. Extranodal involvement is frequent, and especially in the bone marrow, spleen, gastrointestinal tract and Waldeyer's ring, but skin is rarely affected. A 47-year-old male presented with a 40 day history a nodule on the abdomen on the abdomen. The histopathologic examination showed numerous atypical, small to medium sized lymphoid cells in the entire dermis. Immunohistochemically, the tumor cells were positive for CD20, CD5, CD79a and cyclin D. Our patient showed complete disappearance of his skin lesions and lymphadenopathy after combination chemotherapy.
Abdomen
;
B-Lymphocytes
;
Bone Marrow
;
Cyclin D
;
Dermis
;
Drug Therapy, Combination
;
Gastrointestinal Tract
;
Humans
;
Lymphatic Diseases
;
Lymphocytes
;
Lymphoma
;
Lymphoma, Mantle-Cell
;
Male
;
Middle Aged
;
Neoplasm Metastasis
;
Skin
;
Spleen
7.A clinical study in the diagnostic efficacy of mammography todetecty the breast carcinoma.
Jong Whan CHO ; Seung Hoi PARK ; Hye Soon PARK ; Hong Jun CHO ; Young Sik KIM
Journal of the Korean Academy of Family Medicine 1991;12(11):14-20
No abstract available.
Breast Neoplasms*
;
Breast*
;
Mammography*
8.The Significance of Increased Signal Intensity in MR Imaging among Male Welders.
Dong Mug KANG ; Ho Chu PARK ; Hye Sook SON ; Jun Han PARK ; Young Joon LEE
Korean Journal of Occupational and Environmental Medicine 1998;10(1):41-52
A purpose of present study is to provide basic information evaluating the utility of Magnetic Resonance imaging as a biological marker estimating manganese effects to central nervous system among welders, which is conducted by comparing urinary and blood manganese concentrations and signal intensities of brain MR images between exposed group and non-exposed group, evaluating the objectivity of subjective grading estimated by correlations between Pallidal signal intensity index (P. I) and subjective grades among exposed group, and comparing the difference of signal intensities according to presence of neurologic symptoms, signs and exposure variables among the exposed group. The exposed group is composed of 11 welders complaining severe symptoms or showing neurological signs, and the non-exposed group is composed of 5 patients who admitted a hospital. Urinary manganese concentrations and signal intensities in T1-weighted MR images among exposed group were higher than those of the non-exposed group significantly, which exhibits that increased signal intensities in T1-weighted MR image represent the effect of manganese exposure. P. Is among the exposed group revealed relatively high correlations with subjective grades ( gamma =0.63, p=0.037) , which suggests the objectivity of subjective grade. Signal intensity in globus pallidus was a suitable single variable representing the effect of manganese accumulation in C.N.S system appropriately, which was verified as follows ; Increased signal intensities among the exposed group had the highest frequency and intensity in the globus pallidus, and the P.I. had a relatively high correlation coefficient ( gamma 0.62, p=0.044) with total score of subjective grades. Signal intensity with subjective grading in globus pallidus represented very high correlation gamma =0.97, p=0.00) with total score of subjective grades, and had a similar correlation coefficient with many variables. It is hard to argue that signal intensities are markers representing pathologic change in C.N.S system or can be used as a diagnostic tool for manganese intoxication, because signal intensities had no difference between the exposed group and the non-exposed group according to presence of neurological signs.
Biological Markers
;
Brain
;
Central Nervous System
;
Globus Pallidus
;
Humans
;
Magnetic Resonance Imaging*
;
Male*
;
Manganese
;
Neurologic Manifestations
9.Effect on body weight control through behavior, diet, exercise therapy in obese patients.
Hye Soon PARK ; Young Sun JUNG ; En Su SHIN ; Myung Wha KIM ; Chul Jun KIM
Journal of the Korean Academy of Family Medicine 1993;14(4):250-257
No abstract available.
Body Weight*
;
Diet*
;
Exercise Therapy*
;
Humans
10.Clinical Study of Plasma A.V.P Levels in Children with Meningitis.
Jun Gun KIM ; Hye Kyung CHO ; Mea Young CHUNG ; Dong Hyuck KUM
Journal of the Korean Pediatric Society 1985;28(4):325-329
No abstract available.
Child*
;
Humans
;
Meningitis*
;
Plasma*