PURPOSE: This study was to serve the sexual health education of the hysterectomy patients and to get the basic data of the nursing intervention on sexual health education. Sexual health education for the patients is an independent function as well as a professional responsibility of nurses. METHOD: The subjects were composed of 108 post-op patients who had undergone doing a hysterectomy 5 to 10 days previously and 101 nurses at OBGY hospitals. For data analysis, the study executed a frequency, mean, standard deviation, t-test, ANOVA, Duncan Multiple Range test and Spearman's rho correlation coefficient, in accordance with the purpose of the study using SPSS Win 10.0. RESULT: Mean score of the needs degree of sexual health education was 3.30 point. The need for education was highest in the sexual health promotion with education related to sexual interaction the lowest. Mean score of the nurses' teaching performance degree of sexual health education was 1.80 point. The nurses' teaching performance was highest in the sexual health promotion. There exist significant correlations between the degree of patients' educational needs and the degree of nurses' teaching performance on physiosexual (rho=-.667, p< .05), psychosexual (rho=.762, p< .05), sexual interaction (rho=.667, p< .05) respectively. There was no significant difference on sexual health promotion (rho=.359, p> .05). CONCLUSION: The degree of sexual health education needs of hysterectomy patients was very high. Therefore, continuous nursing education program should be developed and provided for the promotion of the performance of sexual health education as the nursing professional role.
Education* ; Education, Nursing ; Humans ; Hysterectomy* ; Nursing ; Professional Role ; Reproductive Health* ; Statistics as Topic

No abstract available.
Gastroesophageal Reflux* ; Pneumonia*

Spindle cell carcinoma of the upper aerodigestive tract mucosa was usually presented as polypoid mass and shows squamous cell carcinoma or dysplasia in the surface and underlying spindle cell proliferation. The spindle cell area discloses a variable pattern of sarcoma including rare osteosarcoma of 0~20% incidence. The histogenetic origin of the spindle cell component is now considered a metaplasia of squamous cell carcinoma. We experienced a case of spindle cell carcinoma of larynx showing massive underlying bone formation with proliferation of osteoclast-like cells in 75 year-old man. The immunohistochemical study demonstrates positive reaction with cytokeratin in area of squamous cells and with vimentin in area of spindle cells and osteoclasts. There are very focal reactivity for high molecular weight cytokeratin in spindle cell area.
Incidence

OBJECTIVES: Cadherin/catenin adhesion complex is fundamentally involved in epithelial cancer invasion and metastasis. E-cadherin and EGFR colocalize on the basolateral membrane of epithelial cell and EGF down-regulate E-cadherin expression. In the invasion and metastasis of cancer, E-cadherin expression is decreased and growth factors receptor is overexpressed. The present study was aimed to find the role of E-cadherin, beta-and gamma-catenin, growth factors and its receptors in cervical cancer cell lines. METHODS: The cervical cancer cell cultures were treated with different time duration of EGF 30 ng/ml and TGF-a 10 ng/ml(0, 10 min, 20 min, 30 min, 1 hr, 2 hr, 4 hr, 8 hr, 24 hr). The change in cancer cell morphology and the changes in E-cadherin, beta- and gamma-catenin, EGFR and activated EGFR expression were studied with a western blot analysis and an immunoprecipitation. RESULTS: Through a western blot analysis, E-cadherin 120 kDa band and EGFR 170 kDa band were expressed in CaSki, HT-3 and ME-180 cell line, which showed epithelial contact growth. 1n these 3 cell lines, expression of E-cadherin did not decrease with time dependent manner. after the treatment of EGF and TGF- alpha. The expression of EGFR decreased and activated EGFR expression increased in 30 minutes to 1 hour but decreased subsequently. When the cells treated with EGF, there were no change in beta-and gamma-catenin expression with there dependent manner. The tyrosine phosphorylation of beta-and gamma-catenin increased in 30 minutes to 1 hour but decreased subsequently with activated EGFR. CONCLUSION: This study showed that an activated EGFR which has involved with tyrosine phosphorylation of beta- and gamma-catenin influenced by growth factors rather than expression of E-cadherin, has a role in the invasion and metastasis of the cervical cancer.
Blotting, Western ; Cadherins* ; Cell Culture Techniques ; Cell Line* ; Epidermal Growth Factor* ; Epithelial Cells ; gamma Catenin* ; Immunoprecipitation ; Intercellular Signaling Peptides and Proteins ; Membranes ; Neoplasm Metastasis ; Phosphorylation* ; Transforming Growth Factor alpha* ; Tyrosine* ; Uterine Cervical Neoplasms*

BACKGROUND: EGF and TGF-a are ligands for the EGF-receptor and act as mitogens for a variety of tissues. TGF-a, in particular, has been implicated as an autocrine growth factor for several cancer cell lines. TGF-B exerts an inhibitory effect on the growth of most epithelial cell types, and the loss of responsiveness to this growth inhibition has been implicated in the development of a variety of human cancers. In the present study, we evaluate whether EGF, TGF-a and TGF-B modulate apoptosis and cell cycle progression in cervical cancer cell lines. MATERIALS & METHODS: The effect of EGF, TGF-a and TGF-B on apoptosis and cell cycle such as CaSki and HeLa cell lines was analysed by flow cytometry RESULTS: 1. TGF-B did not induce apoptosis in CaSki and HeLa cell lines. 2. TGF-B as well as EGF, TGF-a, did not affect the process of apoptosis significantly. 3. The time to occur apoptosis was different between CaSki and HeLa cells treated by growth factots. 4. G1 phase was the checkpoint in CaSki and HeLa cells treated with TGF-B. CONCLUSION: These results suggest that TGF-B as well as EGF, TGF-a does not induce apoptosis and cell growth inhibition.
Apoptosis* ; Cell Cycle Checkpoints* ; Cell Cycle* ; Cell Line* ; Epidermal Growth Factor* ; Epithelial Cells ; Flow Cytometry ; G1 Phase ; HeLa Cells ; Humans ; Ligands ; Mitogens ; Uterine Cervical Neoplasms*

The Fig. 5A was given incorrectly.

No abstract available.
Antioxidants* ; Oxidative Stress*

BACKGROUND: The purpose of study to present the basic data for enhancing the performance level of the dental clinic infection prevention through the actual condition of the implementation for dental treatment infection prevention aimed at dental hygienists in each hospital. METHODS: We carried out a survey targeting 69 dental hygienists in the dental college hospital, 42 in the dentist of the Dentistry in General Hospital, 51 in the dental clinic and 38 in the dentist's office and the medical institutions surveyed, and we used frequency analysis and chi-square analysis by using SPSS (Ver. 18.0). RESULTS: The experiences wounded in the body by sharp instruments or needles contaminated with patients' blood or saliva were on average in 86.5% of the dental hygienists, and people who disinfected the wound with disinfectants after washing their own hands and squeezing blood as the method to fight the wound was 73.4%. The dental clinic was the highest in case of the rate of wearing gloves, and the dental clinic was the highest in the case of the rate of wearing a mask. The use of the liquid soap containing antimicrobial was the highest as 28.0% in the dental college hospital in case of 'the cleanser to be used for washing their own hands'. In the multiple response for dental treatment mechanical equipment management apparatus and the actual condition to be equipped with medicines and the survey in sterilization, Povidone was the highest as 28% in the dental college, and surface disinfectants were being used in some hospitals. CONCLUSION: To prevent the infection in the consultation room, dental hygienists should thoroughly recognize Dental Treatment Infection Prevention Standards, and the research measures or administrative support of the government and the organs concerned is needed a lot.
Dental Clinics ; Dental Hygienists ; Dentistry ; Dentists ; Disinfectants ; Hand ; Hospitals, General ; Humans ; Masks ; Needles ; Povidone ; Saliva ; Soaps ; Sterilization

Patients with AIDS frequently present with pulmonary complications which are associated with a high mortality rate and infections are the most important cause of lung infiltrates. In addition to pneumonia caused by Pneumocystis carinii, which was noted in early reports of the syndrome, a variety of other severe pulmonary disorders may occur. Frequently more than one organism is found in a single patient and among these, combined infections of Pneumocystis carinii and cytomegalovirus are the most common. We experienced a case of combined Pneumosytis carinii and Mycobacterium tuberculosis infection as a pulmonary manifestation of AIDS in a 38-year-old man. In bronchoalveolar larvage, bronchial washing and brushing, and sputum smear specimens, Pneumocystis carinii organisms were recognized, especially in Gomori's methenamine silver stains. Transbronchial lung biopsy specimen revealed intra-alveolar frothy exudates composed of collections of Pneumocystis carinii organisms as well as several granulomas with central caseous necroses.
Mortality ; Biopsy

PURPOSE: to test of the reliability and validity of the Disabled's Motivation for Rehabilitation Scale. which was developed in 2002. METHOD: An experimental version of the scale was distributed to a sample of 441 disabled with ages above 18 and below 80 years. The subjects of the test-retest were 60 disabled. RESULTS: revealed a satisfactory level of test-retest and internal consistency. The overall fit of the factor model to the data was good. Correlation among the subscales revealed a simple pattern that, in general. provides support for the self- determination continuum and the construct validity. In testing concurrent, criterion-validity, there was a positive correlation between the motivation scores for rehabilitation and the Health-Related Hardiness scores and a negative correlation between the motivation scores for rehabilitation and the Learned Helplessness scores. CONCLUSION: The Disabled's Motivation for Rehabilitation Scale revealed a useful instrument with a high degree of reliability and validity. In this sense, this instrument can be effectively utilized in rehabilitative nursing for the disabled.
Helplessness, Learned ; Motivation* ; Nursing ; Rehabilitation* ; Reproducibility of Results*