Spindle cell carcinoma of the upper aerodigestive tract mucosa was usually presented as polypoid mass and shows squamous cell carcinoma or dysplasia in the surface and underlying spindle cell proliferation. The spindle cell area discloses a variable pattern of sarcoma including rare osteosarcoma of 0~20% incidence. The histogenetic origin of the spindle cell component is now considered a metaplasia of squamous cell carcinoma. We experienced a case of spindle cell carcinoma of larynx showing massive underlying bone formation with proliferation of osteoclast-like cells in 75 year-old man. The immunohistochemical study demonstrates positive reaction with cytokeratin in area of squamous cells and with vimentin in area of spindle cells and osteoclasts. There are very focal reactivity for high molecular weight cytokeratin in spindle cell area.
Incidence

This study was conducted to investigate correlation theory of planned behavior, self efficacy and health locus of control about smoking cessation behavior for university student. We sampled 204 university student smokers using questionnaires and analyzed the data using Pearson correlation coefficient. The results of this study were as follows : 1. There were significant positive correlation between theory of planned behavior(intention : r=.215, p=.005, attitude : r=.160, p=.025, perceived behavior control : r=.298, p=.000) and self efficacy. 2. There were significant positive correlation between theory of planned behavior(attitude : r=.228, p=.002) and internal health locus of control. There were significant positive correlation between theory of planned behavior(attitude : r=.203, p=.004, subjective norm : r=.141, p=.047) and external health locus of control. There were significant negative correlation between theory of planned behavior(perceived behavior control : r=-.152, p=.034) and accidental health locus of control. This study has shown a correlation between theory of planned behavior and self efficacy and health locus of control. As a result of these findings, I suggest to develop the intervention program for smoking cessation.
Behavior Control ; Humans ; Internal-External Control* ; Self Efficacy* ; Smoke* ; Smoking Cessation* ; Smoking* ; Child Health

No abstract available.
Asthma* ; Atrial Natriuretic Factor* ; Egg Hypersensitivity* ; Ovum*

PURPOSE: This study describes the ecological variables effect on child abuse potential and the results from a prevention program for parents with disabled children aiming at decreasing child abuse potential. METHOD: Data was collected from 30 parents with disabled preschoolers attending an early education center in a community. The program consisted of handouts, small group lectures, support group meetings on understanding the disabled child-parents relationship, communication skill improvement, non-punitive discipline techniques, and influences of child abuse. A non equivalent pre-post test design was employed. RESULT: Ecological variables, and parenting self-efficacy, had a significant effect on child abuse potential in parents with a disabled child. By regression parenting self-efficacy showed(27.1%) child abuse potential. Both parenting self-efficacy and beliefs in corporal punishment directly related to (52.0%) child abuse potential in parents. The program was effective inbringing some positive changes on pareting self-efficacy beliefs in corporal punishment, and child abuse potential toward disabled children. However, marital discord was not significantly effected. CONCLUSION: Child abuse prevention programs should decrease thechild abuse potential in parents. Thus I recommend a child abuse prevention program development; for parents with disabled adolescents, and teachers in disabled child education.
Adult ; Child ; Child Abuse/*prevention & control ; Child, Preschool ; *Disabled Children ; Female ; Humans ; Korea ; *Parenting ; Parents/*education

This study aimed at assessing the usefulness of paraffin wax sections for demonstration of ER(estrogen receptor) and PR(progesterone receptor), using brief microwave processing rather than proteolytic predigestion. The receptor status of a breast cancer is often into consideration when planning treatment nowadays. As biochemical receptor assays require large amount of fresh tumor tissue and are not always available for all tumors, pathologists are now increasingly asked to provide a service for the assessment of the receptor status in tissue routine sections. Until recently, immunohistochemical demonstration of receptors was used in frozen sections. Therefore, routinely processed paraffin wax sections of 25 cases of breast carcinoma with known ER and PR concentrations, estimated by the standard DCC(dextran-coated charcoal) biochemical assay, were examined using the ABC immunoperoxidase technique. The results were assessed semiquantitably, using a five grade scoring system. Of the 25 cases examined, with DCC cutoff point being <10 fmol,71% and 75% in positivity of each ER, PR receptor is concordant. Statistic analysis demonstrates high relationship between scoring system of IH method and DCC value in ER (R=0.6061, p=0.001) and PR (R=0.5832, p=0.001). The IH method can provide easily assessed reliable positive information about ER, PR status of breast carcinoma using routinely processed paraffin wax sections.
Breast Neoplasms

No abstract available.
Adenoma* ; Toes*

To evaluate the relationship between the expression of CA 125, CA 19-9, and CA 15-3 and ovarian epithelial tumors, immunohistochemical stainings were performed and analyzed to the types of tumor, and the degree o malignancy and differentiation in the total 42 cases. The results were summarized as follows: 1) The expression of CA 19-9 and CA 15-3 was demonstrated in most cases of benign, borderline and malignant mucinous tumors. All types tumors were negative for CA 125. 2) All types of serous tumors including benign, borderline and malignant revealed strong positive reaction for CA 125 and CA 15-3 in contrast to some weak positivity for CA 19-9. Expression of CA 125 was significantly increased in high grade serous adenocarcinomas compared with low of grade. 3) Endometrioid carcinomas revealed strong positive reaction for CA 15-3 in contrast to some positivity for CA 125 and CA 19-9. One case of Brenner tumor expressed CA 19-9 and CA 15-3 without expression of CA 125. 4) Serum CA 125 levels were elevated in 80% and CA 15-3 levels in 100% of ovarian epithelial malignancy. The correlation between serum levels and staining intensities was moderate.
Adenocarcinoma

PURPOSE: We reviewed all the articles on effect of smoking cessation intervention to find out the way of improvement of it. METHOD: 48 researches were published in Korean journals from 1980 to 2007. The research were analyzed according to: major of first author, subjects, application of theoretical framework, contents of intervention, a term of intervention, the time of evaluation on effect of interventions, research design, dependant variables, and effect of interventions. RESULTS: Research on effect of smoking cessation intervention increased rapidly in the 2000's. At this time. 72.9% of research was published. Most of research subject were students. Theoretical framework were applied in 20.8% of articles. The most common intervention was education(39.4%). The effect of combined program on outcome variable was found to be stronger than only education program. Experimental design was used in 29.2% and quasi-experimental design was adapted in 43.8% of articles. 1-6 months intervention was in 35.4%. The long term intervention more than 1month was found to be effective. Health behavior related index was measured as a dependant variable in 62.3%. CONCLUSION: Accordingly, long term program to apply to various subject is needed.
Education ; Health Behavior ; Humans ; Research Design ; Research Subjects ; Smoking Cessation*

PURPOSE: The purpose of this study was to compare the premenstrual syndrome (PMS) and the relationships among PMS, perfection, and anxiety in nursing college students and general college students. METHODS: The questionnaire survey was carried out with a convenience sample of 215 college students. The MDQ (Menstrual Distress Questionnaire), APS-R (Almost Perfect Scale-Revised), STAI (State and Trait Anxiety Inventory) were used. The data were collected from June to October, 2011. Data analysis included frequency, chi2-test, t-test, and Pearson correlation. RESULTS: There were significant differences in PMS and perfection but there not in anxiety between nursing college students and general college students. There were significant correlations among PMS, perfection and anxiety in nursing college students, and there were significant correlations among PMS and anxiety in general college students but not significant correlations among PMS and perfection. CONCLUSION: The findings suggest that to provide effective interventions for PMS in college students, it is necessary to design nursing interventions that consider perfection and anxiety.
Anxiety* ; Female ; Humans ; Menstruation ; Nursing ; Premenstrual Syndrome* ; Surveys and Questionnaires ; Statistics as Topic

PURPOSE: This study was carried out to identify premenstrual discomforts and coping patterns and their effects. METHOD: The participants of this study were 297 female university students in C area. The Menstrual Discomfort Questionaire (MDQ) and coping method lists were used as measurement tools. RESULTS: There were significant differences premenstrual discomforts according to age (F=5.76, p=.003) and according to health condition (F=3.43, p=.034). The mean scores of the sub-categorical factors of premenstrual discomfort were 2.35 points for pain, 2.29 for instability and 2.25 for water retention. The worst symptoms among the subcategories of premenstrual discomfort were as follows: backache (M=2.68) in the pain subcategory, irritability (M=2.53) in the instability subcategory and swelling(M=2.40) in the water retention subcategory. Their common coping patterns were "coping according to menstrual period", "active behavioral coping" and "evasional coping". Frequently used coping methods were "taking a rest and sleep (99.3%)" and "taking a warm shower (86.2%)". Effective coping methods were "taking a rest and sleep (89.5%)" and "taking a warm shower (87.1%)". CONCLUSION: Most participants have their own coping pattern. Some methods were very effective to PMS but some were not effective to PMS. To manage PMS, effective coping methods should be encouraged for female university students. To keep up with effective coping, education and counseling should be continued. It is considered necessary to make the same research with a larger number of samples and more specified assessment.
Back Pain ; Counseling ; Education ; Female ; Humans ; Water