1.Traumatic Rupture of the Superior Oblique Muscle Tendon.
Hye Jin CHUNG ; Ji Won BAEK ; Young Chun LEE
Korean Journal of Ophthalmology 2014;28(3):265-267
Traumatic rupture of the superior oblique muscle is rare. We report a case of a 54-year-old man injured by the metal hook of a hanger, resulting in a rupture of the superior oblique muscle tendon. He complained of torsional diplopia when in the primary position. The distal margin of the superior oblique muscle was reattached to sclera 5 and 9 mm apart from the medial insertion of the superior rectus muscle. One week after the operation, torsional diplopia disappeared. However, a 4-prism diopter ipsilateral hypertropia was observed. Three months later, hypertropia gradually increased to 20 prism dioptors and the second operation was done to correct vertical diplopia.
Diplopia/etiology/physiopathology/surgery
;
Eye Injuries/complications/*diagnosis/surgery
;
*Eye Movements
;
Humans
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Male
;
Middle Aged
;
Oculomotor Muscles/*injuries/physiopathology/surgery
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Ophthalmologic Surgical Procedures/*methods
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Strabismus/etiology/physiopathology/surgery
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Tendon Injuries/complications/*diagnosis/surgery
2.Clinical Analysis of Surgical Geriatric Patients over 65 Years of Age.
Seong Lae CHO ; Jae Won BAEK ; Eak Ryong LEE ; Mun Gyu PARK
Journal of the Korean Surgical Society 1999;56(2):285-293
BACKGROUND: Advanced age alone should not be a serious deterrent to surgery. Preoperative evaluation of concomitant illness, operation time, accurate and minimal, but adequate surgery will serve to minimize morbidity and mortality in elderly patients. METHODS: The total number of surgical patients admitted to Kwang Hye Hospital, Pusan, from March 1994 to August 1996 was 3211, and the number of surgical geriatric patients admitted during the same period was 214. Operations were performed on 139 patients. We recorded information about age, sex, anesthesia type, operation time, non malignancy vs malignancy, emergency vs elective "Surgery", coexisting disease, and APACHE II score, and we examined the patients for results affecting postoperative morbidity and mortality. RESULTS: Postoperative complications occured in 55 cases (39.6%), and the operative mortality was 2.2%. The significant factors affecting postoperative morbidity were emergency operation, malignancy and APACHE II score. The operation time and coexisting diseases were not significant. Age had little effect on the postoperative prognosis CONCLUSIONS: Performance of elective surgery and preoperative evaluation of the APACHE II score are important factors.
Aged
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Anesthesia
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APACHE
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Busan
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Emergencies
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Humans
;
Mortality
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Postoperative Complications
;
Prognosis
3.Emotional and Behavioral Problems Related to Smartphone Overuse in Elementary School Children.
Hye Won BAEK ; Yun Mi SHIN ; Kyoung Min SHIN
Journal of Korean Neuropsychiatric Association 2014;53(5):320-326
OBJECTIVES: The objective of this study was to assess the characteristics of smartphone use in elementary school children and the emotional and behavioral problems associated with smartphone overuse and addiction. METHODS: Children referred to a community based pediatric mental health center were screened for smartphone addiction and related problematic behavior using the Smartphone Addiction Proneness Scale and the Korean version of the Child Behavior Checklist (CBCL). RESULTS: 1) Statistically significant differences in gender, usage time, ownership, and internalization symptoms (somatization, anxiety/depression, withdrawal) were observed between the smartphone excessive user group and the control group. 2) Variants showing the most significant correlation with smartphone addiction were usage time, internalization problems somatization, anxiety/depression, withdrawal, aggressive behaviors, and total behavior problems. CONCLUSION: The results of this study indicated an association of addiction tendency in elementary school children with internalization symptoms. Close observation in the familial and academic setting may be important for children at high risk for smartphone addiction.
Checklist
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Child Behavior
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Child*
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Humans
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Mental Health
;
Ownership
4.Emotional and Behavioral Problems Related to Smartphone Overuse in Elementary School Children.
Hye Won BAEK ; Yun Mi SHIN ; Kyoung Min SHIN
Journal of Korean Neuropsychiatric Association 2014;53(5):320-326
OBJECTIVES: The objective of this study was to assess the characteristics of smartphone use in elementary school children and the emotional and behavioral problems associated with smartphone overuse and addiction. METHODS: Children referred to a community based pediatric mental health center were screened for smartphone addiction and related problematic behavior using the Smartphone Addiction Proneness Scale and the Korean version of the Child Behavior Checklist (CBCL). RESULTS: 1) Statistically significant differences in gender, usage time, ownership, and internalization symptoms (somatization, anxiety/depression, withdrawal) were observed between the smartphone excessive user group and the control group. 2) Variants showing the most significant correlation with smartphone addiction were usage time, internalization problems somatization, anxiety/depression, withdrawal, aggressive behaviors, and total behavior problems. CONCLUSION: The results of this study indicated an association of addiction tendency in elementary school children with internalization symptoms. Close observation in the familial and academic setting may be important for children at high risk for smartphone addiction.
Checklist
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Child Behavior
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Child*
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Humans
;
Mental Health
;
Ownership
5.The role of K+ channels on spontaneous action potential in rat clonal pituitary GH3 cell line.
Hyewhon RHIM ; Hye Jung BAEK ; Won Kyung HO ; Yung E EARM
The Korean Journal of Physiology and Pharmacology 2000;4(2):81-90
The types of K+ channel which determine the pattern of spontaneous action potential (SAP) were investigated using whole-cell variation of patch clamp techniques under current- and voltage-clamp recording conditions in rat clonal pituitary GH3 cells. Heterogeneous pattern of SAP activities was changed into more regular mode with elongation of activity duration and afterhyperpolarization by treatment of TEA (10 mM). Under this condition, exposure of the class III antiarrhythmic agent E-4031 (5 micrometer) to GH3 cells hardly affected SAP activities. On the other hand, the main GH3 stimulator thyrotropin-releasing hormone (TRH) still produced its dual effects (transient hyperpolarization and later increase in SAP frequency) in the presence of TEA. However, addition of BaCl2 (2 mM) in the presence of TEA completely blocked SAP repolarization process and produced membrane depolarization in all tested cells. This effect was observed even in TEA-untreated cells and was not mimicked by higher concentration of TEA (30 mM). Also this barium-induced membrane depolarization effect was still observed after L-type Ca2+ channel was blocked by nicardipine (10 micrometer). These results suggest that barium-sensitive current is important in SAP repolarization process and barium itself may have some depolarizing effect in GH3 cells.
Action Potentials*
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Animals
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Barium
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Cell Line*
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Hand
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Membranes
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Nicardipine
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Patch-Clamp Techniques
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Rats*
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Tea
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Thyrotropin-Releasing Hormone
6.Comparison of bronchial responsiveness assessing dose-response slope between cough-variant asthma and classic asthma in young children.
Jung Won YOON ; Hye Young HUR ; Hye Mi JEE ; Ji Hyeon BAEK ; Hyeong Yoon KIM ; Youn Ho SHIN ; Man Yong HAN
Allergy, Asthma & Respiratory Disease 2013;1(4):309-313
PURPOSE: Little data is currently available on the use of the impulse oscillometry system (IOS) parameter in analyzing the lung function of young children with cough-variant asthma (CVA) and classic asthma. The aims of this study were to evaluate the bronchial responsiveness between patients with CVA and those with classic asthma using dose-response slope and various cutoff values. METHODS: A methacholine challenge test and a pulmonary function test were performed in 43 children with classic asthma and 26 children with CVA using IOS, and the respiratory resistance (Rrs) and reactance (Xrs) were obtained. The bronchial responsiveness were assessed by provocative concentration causing an 80% fall from baseline in reactance at 5 Hz (PC80_Xrs5) and a 40% increase in resistance at 5 Hz (PC40_Rrs5) and calculating from the degree of dose-response slope (DRS) for airway resistance and reactance. RESULTS: There was no significant difference in base lung function between the two groups. However, the mean DRS_Xrs5 and the number who showed more than an 80% fall in reactance were significantly higher in classic asthma group than those in CVA group (P=0.040 and P=0.040, respectively). CONCLUSION: The use of DRS in oscillatory reactance at 5 Hz is useful for the differential diagnosis of classic asthma and CVA based on bronchial hyperresponsiveness.
Airway Resistance
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Asthma*
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Bronchial Hyperreactivity
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Child*
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Cough
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Diagnosis, Differential
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Humans
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Lung
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Methacholine Chloride
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Oscillometry
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Respiratory Function Tests
7.Isolated Leptomeningeal Neurosarcoidosis.
Yun Kyung LA ; Hye Ihn KIM ; Min Seok BAEK ; Kyoung Won BAIK ; Yoon Jin CHA ; Won Joo KIM
Journal of the Korean Neurological Association 2017;35(1):48-49
No abstract available.
Central Nervous System
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Epilepsy
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Sarcoidosis
8.Report for Development of Korean Portable Cardiopulmonary Bypass II. Experimental Study of Portable Cardiopulmonary Bypass for Emergency Cardiopulmonary Resuscitation after Cardiac Arrest in Normal Dogs.
Hyoung Mook KIM ; In Sung LEE ; Man Jong BAEK ; Kyung SUN ; Kwang Taik KIM ; Hye Won LEE ; Gyu Baek LEE ; Joon Geun JANG ; Jong Won KIM ; Hak Jae KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1998;31(12):1147-1158
BACKGROUND: Portable cardiopulmonary bypass (CPB) technique has been used increasingly as a potent and effective option for emergency cardiopulmonary resuscitation (CPR) because it can maintain more stable hemodynamics and provide better survival than conventional CPR techniques. This study was designed to develop a prototype of Korean portable CPB system and, by applying it to CPR, to discriminate whether it would be superior to standard open-chest CPR. MATERIAL AND METHOD: By using adult mongrel dogs, open-chest CPR (OCPR group, n=4) and portable-CPB CPR (CPB group, n=4) were compared with respects to restoration of spontaneous circulation (ROSC), hemodynamics, effects on blood cells, blood gas patterns, biochemical markers, and survivals. Ventricular fibrillation-cardiac arrest (VF-CA) of arrest (VF-CA) of 4 minutes followed by basic life support (BLS) of 15 minutes was applied in either group, which was standardized by the protocol of American Heart Association. Then, advanced life support (ALS) was applied to either group under the support of internal cardiac massage or CPB. ALS was maintained until ROSC was achieved but not longer than 30 minutes regardless of the presence of ROSC. All of the measured values were expressed as means+/-SD percent change from baseline. RESULT: During the early ALS, higher mean arterial pressure was maintained in CPB group than in OCPR group (90+/-19 vs. 71+/-32 %; p<.05) and lower mean pulmonary arterial pressure was also maintained in CPB group than in OCPR group (105+/-24 vs. 146+/-6%; p<.05). ROSC was achieved in all dogs. Post-ROSC levels of hematocrit, RBC, and platelet were decreased and plasma free hemoglobin was increased significantly in CPB group compared to OCPR group (p<.05). Changes in blood gas patterns, lactate, and CK-MB levels were not different between groups. Early mortality was seen in 3 dogs in OCPR group (survival time 31+/-36 hours) and 2 in CPB group (228+/-153 hours, p=ns). The remainders in both groups showed prolonged survival. CONCLUSION: These findings indicate that portable CPB can be effective to maintain stable hemodynamics during cardiac arrest, to achieve ROSC and to prolong survival. Further study is needed to refine the portable CPB system and to meet clinical challenges.
Adult
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American Heart Association
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Animals
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Arterial Pressure
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Biomarkers
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Blood Cells
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Blood Platelets
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Cardiopulmonary Bypass*
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Cardiopulmonary Resuscitation*
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Dogs*
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Emergencies*
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Heart Arrest*
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Heart Massage
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Hematocrit
;
Hemodynamics
;
Humans
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Lactic Acid
;
Mortality
;
Plasma
9.Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia.
Ki Young SONG ; Jin Hye PARK ; Yoon Jung CHO ; Won Ki BAEK ; Ki Young KWON ; Heung Sik KIM ; Chin Moo KANG
Journal of the Korean Pediatric Society 2000;43(3):327-334
PURPOSE: Acute promyelocytic leukemia (APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid (ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARalpha protein possibly being the direct target of ATRA. However, ATRA treatment has two clinical limitations, namely, retinoic acid syndrome and retinoic resistance. Recently, it has been shown that arsenic trioxide used in some traditional Chinese remedy is very effective in retinoic resistant APL treatment. We tried to observe arsenic effect on cell lines and APL patient cells. MEHTODS: We investigated arsenic trioxide-induced apoptosis on APL, HL60, K562, KPH1 cell lines through MTT assay, DNA fragmentation assay and morphologic features. RESULTS: In MTT assay, cell survival rate decreased as the concentration of arsenic trioxide increased. In DNA fragmentation assay with HL60 cell line, DNA fragmentation was more frequent in high concentrations of arsenic trioxide than in low concentrations. During arsenic trioxide treatment, the morphologic change in bone marrow cells of APL patient, included nuclear differentiation and dark cytoplasmic granule during arsenic trioxide treatment. Serum arsenic reached peak level at 4hr after injection. We experienced a case of a 9-year-old male with APL who had relapsed after cessation of retinoic acid treatment. The patient successfully achieved remission following arsenic trioxide treatment without bone marrow depression and exacerbating bleeding diathesis. CONCLUSION: Arsenic trioxide can be used effectively to treat APL patients by inducing apoptosis and partial differentiation in tumor cells. The precise cellular and molecular mechanisms of its therapeutic effects remain to be determined.
Apoptosis
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Arsenic*
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Asian Continental Ancestry Group
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Bone Marrow
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Bone Marrow Cells
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Cell Line
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Cell Survival
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Child
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Cytoplasmic Granules
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Depression
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Disease Susceptibility
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DNA Fragmentation
;
Hemorrhage
;
HL-60 Cells
;
Humans
;
Leukemia, Promyelocytic, Acute*
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Male
;
Tretinoin
10.The Effect of Work Characteristics on Dermatologic Symptoms in Hairdressers.
Pil Kyun JUNG ; June Hee LEE ; Ji Hye BAEK ; Jungho HWANG ; Jong Uk WON ; Inah KIM ; Jaehoon ROH
Annals of Occupational and Environmental Medicine 2014;26(1):13-13
OBJECTIVES: Hairdressers in Korea perform various tasks and are exposed to health risk factors such as chemical substances or prolonged duration of wet work. The objective of this study is to provide descriptive statistics on the demographics and work characteristics of hairdressers in Korea and to identify work-related risk factors for dermatologic symptoms in hairdressers. METHODS: 1,054 hairdressers were selected and analyzed for this study. Independent variables were exposure to chemical substances, the training status of the hairdressers, and the main tasks required of them, and the dependent variable was the incidence of dermatologic symptoms. The relationships between work characteristics and dermatologic symptoms were evaluated by estimating odds ratios using multiple logistic regression analysis. RESULTS: Among the 1,054 study subjects, 212 hairdressers (20.1%) complained of dermatologic symptoms, and the symptoms were more prevalent in younger, unmarried or highly educated hairdressers. The main tasks that comprise the majority of the wet work were strictly determined by training status, since 96.5% of staff hairdressers identified washing as their main task, while only 1.5% and 2.0% of master and designer hairdressers, respectively, identified this as their main task. Multiple logistic regressions was performed to estimate odds ratios. While exposure to hairdressing chemicals showed no significant effect on the odds ratio for the incidence of dermatologic symptoms, higher odds ratios of dermatologic symptoms were shown in staff hairdressers (2.70, 95% CI: 1.32 - 5.51) and in hairdressers who perform washing as their main task (2.03, 95% CI: 1.22 - 3.37), after adjusting for general and work characteristics. CONCLUSIONS: This study showed that the training status and main tasks of hairdressers are closely related to each other and that the training status and main tasks of hairdressers are related to the incidence of dermatologic symptoms. This suggests that in the future, regulations on working conditions and health management guidelines for hairdressers should be established.
Demography
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Dermatitis, Occupational
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Eczema
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Hair Preparations
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Humans
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Incidence
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Korea
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Logistic Models
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Occupational Health
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Odds Ratio
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Risk Factors
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Single Person
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Social Control, Formal