1.Two Cases of Neonatal Adrenal Hemorrhage.
Kyeong Hye JEONG ; Sung Suk JEON ; Ok Sung JEONG ; Son Sang SEO ; Jung Mee KWEON
Journal of the Korean Pediatric Society 1995;38(10):1411-1416
No abstract available.
Hemorrhage*
2.The clinical significance of serum CA125 and CA19-9 levels in endometriosis.
Tae Jung KANG ; Hye Sung MOON ; Kyung Ah JEONG ; Hye Won JUNG ; Jung Ja AHN
Korean Journal of Obstetrics and Gynecology 2000;43(7):1181-1188
OBJECTIVE: Because endometriosis is difficult to diagnose and has a high recurrence rate after treatment, a reliable serum marker of endometriosis is necessary. Therefore, the aim of this study is to measure the serum levels of CA125 and CA19-9 in patients with endometriosis before and after treatment and during recurrence, and to assess the usefulness of these levels in the diagnosis, clinical follow up and prediction of recurrence in endometriosis. METHODS: Eighty-eight patients who visited the department of Obstetrics and Gynecology of Ewha Mokdong Hospital from January 1994 to December 1998 and were diagnosed as endometriosis by laparoscopy or explo-laparotomy were enrolled as subjects. A retrospective analysis of serum CA125 and CA19-9 levels at 1 month before and 3 to 6 months after initiation of treatment was done. RESULTS: The serum CA125 and CA19-9 levels of endometriosis group(81.0+/-252.5, 36.6+/-53.4 ; mean+/-2SD, U/ml) before treatment was significantly higher than control group(11.6+/-12.8, 9.4+/-8.6)(p<0.05). Overall sensitivity rate for CA125, CA19-9 levels and both was 53.4%, 42.9% and 64.3% respectively. The sensitivity rate for endometriosis, stage 3 and 4(85.4%, 55.0%) was significantly higher than that, stage 1 and 2(p<0.05). The serum CA125 level in endometriosis group showed a significant increment according to stages(p<0.05) while the serum CA19-9 level showed an increasing trend(p=0.055) and both levels decreased significantly after treatment(p<0.05). The serum CA125 level was also higher at recurrence after treatment(p<0.05). CONCLUSIONS: The serum CA125 and CA19-9 levels are a useful marker for diagnosing severity of disease, monitoring efficacy of treatment and predicting recurrence in endometriosis.
Biomarkers
;
Diagnosis
;
Endometriosis*
;
Female
;
Follow-Up Studies
;
Gynecology
;
Humans
;
Laparoscopy
;
Obstetrics
;
Recurrence
;
Retrospective Studies
3.Congenital Heart Disease and Extracardiac Anomalies.
Yong Gyun YOO ; Jae Sung CHO ; Yong Won PARK ; Sung Shik HAN ; Yeon Hye LEE ; Hye Jeong YOON
Korean Journal of Obstetrics and Gynecology 1999;42(3):601-605
Purpose: The diagnostic usefulness of fetal echocardiography in congenital heart disease is well known. One of the indications for fetal echocardiography is presence of extracardiac anomalies and such coexistent congenital heart disease may have important implications for obstetric and neonatal management. MATERIALS AND METHODS: 496 women with singleton pegnancies with amgenital anomalies that underwent penatal care and follow-up in Severance Hospital for 5 years from 1991 to 1995 were evaluated for the incidence of congenital heart disease. RESULTS: The incidence of congenital heart disease in fetuses with the associated extracardiac anomalies were as follows; central nervous system 6.9%(11/160), gastro-intestinal system 10.7%(8/75), genito-urinary sysem 4.7%(4/85), others 5.6%(4/72). Thirty-one of eighty-ane fetuses with congenital heart disease were found to have the associated extracardidac anomalies and ten of them chenoscenal abnormalities. CONCLUSION: We recommend that fetuses with congenital extracardiac anomalies sbould be checked for the presence of congenital heart disease and chmmosomal abnormalities, if needed.
Central Nervous System
;
Echocardiography
;
Female
;
Fetus
;
Follow-Up Studies
;
Heart Defects, Congenital*
;
Humans
;
Incidence
4.Laparoscopic Excision of Anterior Abdominal Wall Tumors: A Case of Desmoid-Type Fibromatosis Arising in the Rectus Muscle.
Ho Jun LEE ; Hye Jeong JEONG ; Jin Woo LEE ; Sung Hoon CHOI
Journal of Minimally Invasive Surgery 2018;21(1):46-48
PURPOSE: Laparoscopic approaches to the anterior abdominal wall are difficult because of the inherent limitations of laparoscopic surgery. METHODS: A 25-year-old young female visited to our hospital with an incidentally-found palpable abdominal mass. Computed tomography revealed a 7-cm round enhancing mass arising from the left posterior rectus sheath. The patient underwent laparoscopic excision of the inner mass arising from the anterior abdominal wall. RESULTS: The operation lasted for 45 minutes and there was no measurable bleeding during the procedure. Pathological assessment revealed that the tumor was a DTF 7.0 cm in size. The patient was discharged on the second postoperative day in good condition, and is currently being followed on a routine basis for surveillance without adjuvant therapy. CONCLUSION: Laparoscopic approach for the anterior abdominal wall tumor could be feasible in select patients. This minimally-invasive approach helps to ensure good cosmetic outcomes and quality of life.
Abdominal Wall*
;
Adult
;
Female
;
Fibroma*
;
Fibromatosis, Abdominal
;
Hemorrhage
;
Humans
;
Laparoscopy
;
Quality of Life
5.A Case of Acquired Tufted Angioma.
Jeong Kil WANG ; Hak Joong LEE ; Han Young WANG ; Hye Kyoung YOON ; Pill Sung PARK
Korean Journal of Dermatology 1998;36(1):164-167
Acquired tufted angioma is a benign, slowly progressive angioma with a typical histological pattern that was first described by Wilson-Jones in 1976. We report a case of acquired tufted angioma in a 19 year old female who had erythematous papules and plaques on the right thigh. Histopathological findings showed multiple capillary lobules in a cannonball arrangement scattered throughout dermis, which was diagnostic of acquired tufted angioma.
Capillaries
;
Dermis
;
Female
;
Hemangioma*
;
Humans
;
Thigh
;
Young Adult
6.An experimental study on the mechanism of nerve regeneration using effects of different distal stumps of silastic tube in resected sciatic nerve model of rats.
Jeong Tae KIM ; Ing Gon KIM ; Ki Ill UHM ; Jae Mann KEW ; Hye Sung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(2):195-207
No abstract available.
Animals
;
Nerve Regeneration*
;
Rats*
;
Sciatic Nerve*
7.PRENATAL SONOGRAPHIC DIAGNOSIS OF CLEFT LIP * PLATE.
Jeong Hoon KANG ; Kyung Suck KOH ; Shi Joon YOO ; Hye Sung WON ; In Sik LEE ; Ahm KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):943-948
No abstract available.
Cleft Lip*
;
Diagnosis*
;
Ultrasonography*
8.Prognosis of extraventricular drainage in childhood tuberculous meningits.
Hye Jeong JEON ; Ki Joong KIM ; Tae Sung KO ; Dong Wook KIM ; Yong Seung HWANG
Journal of the Korean Child Neurology Society 1993;1(1):72-82
No abstract available.
Drainage*
;
Prognosis*
9.Ductal Carcinoma In Situ of the Breast: Comparison of Histologic Classifications and Correlation with Histologic Grade of Coexisting Invasive Ductal Carcinoma.
Sung Ran HONG ; Yee Jeong KIM ; Yi Kyeong CHUN ; Hye Sun KIM ; Hy Sook KIM
Korean Journal of Pathology 1999;33(6):434-442
Recently developed new classifications (Holland, Van Nuys, modified Lagios) of ductal carcinoma in situ (DCIS) linked to outcome have emphasized the importance of nuclear morphology rather than architecture. We have evaluated these three classifications in ductal carcinomas composed of in situ and invasive carcinomas. The reproducibility of three classifications was assessed (n=49), and the histological grade of the DCIS was compared with the histologic differentiation (modified Bloom & Richardson method) and nuclear grade (modified Black method) of the coexisting invasive ductal carcinoma (n=45). According to Holland classification, the DCIS component was poorly differentiated in 51.0%, intermediately differentiated in 40.8%, and well differentiated in 8.2%. Using the Van Nuys classification, the DCIS component was group 3 (high grade with or without necrosis) in 44.9%, group 2 (non-high grade with necrosis) in 28.6%, and group 1 (non-high grade without necrosis) in 26.5%. According to the modified Lagios classification, the DCIS component was high-grade in 42.8%, intermediate-grade in 32.7%, and low-grade in 24.5%. The histologic grades of the three classifications revealed significant correlations between Holland and Van Nuys classification (p<0.0001) and between Holland and modified Lagios classification (p<0.0001), especially in poorly differentiated/group 3/high-grade DCIS. The reproducibility of classification of the DCIS was 71.4% in the Holland, 61.2% in the Van Nuys, and 55.1% in the modified Lagios classifications. The grade of the DCIS showed significant correlation with the grade of coexisting invasive ductal carcinoma (p<0.0001), especially in poorly differentiated/group 3/high-grade DCIS. In conclusion, DCIS grade, determined by the Holland, Van Nuys or modified Lagios classifications, is closely correlated with the histologic grade of the invasive ductal component in tumors composed of in situ and invasive ductal carcinoma, and may be a useful factor to estimate clinical behavior of DCIS. In our experience the Holland classification is recommended for DCIS classification due to its high reproducibility.
Breast*
;
Carcinoma, Ductal*
;
Carcinoma, Intraductal, Noninfiltrating*
;
Classification*
;
Netherlands
10.Cell-assisted lipotransfer in treating uncontrollable sepsis associated perianal fistula: a pilot study
In Seob JEONG ; Sung Hwan HWANG ; Hye Mi YU ; Hyeonseok JEONG
Annals of Coloproctology 2024;40(2):169-175
Purpose:
Surgeons can treat debilitating conditions of uncontrollable complex anorectal fistulas with sepsis, even after repeated fistula surgeries, for curative intention. Adipose-derived stem cells have shown good outcomes for refractory Crohn fistula. Unfortunately, cell therapy has some limitations, including high costs. We have therefore attempted immediate cell-assisted lipotransfer (CAL) in treating refractory complex anal fistulas and observed its outcomes.
Methods:
In a retrospective study, CAL, using a mixture of freshly extracted autologous stromal vascular fraction (SVF) and fat tissues, was used to treat 22 patients of refractory complex anal fistula from March 2018 to May 2021. Preoperative and postoperative assessments were performed with direct visual inspection, digital palpation, and endoanal ultrasonography. A fistula was considered completely healed if (1) the patient had no symptoms of discharge or inflammation; (2) there were no visible secondary openings of fistula tract inside and outside of the anorectal unit and even in the perineum; and (3) there was no primary opening in the anus. The endpoint of complete remission was wound healing without signs of inflammation 3 months after CAL treatment.
Results:
In a total of 22 patients who received CAL treatment, 19 patients showed complete remission, 1 patient showed partial improvement, and 2 patients showed no improvement. One of the 2 patients without improvement at primary endpoint showed complete remission 9 months after CAL. There were no significant adverse effects of the procedure.
Conclusion
We found that the immediately-collected CAL procedure for refractory complex anal fistula showed good outcomes without adverse side effects. It can be strongly recommended as an alternative surgical option for the treatment of complex anal fistula that is uncontrollable even after repeated surgical procedures. However, considering the unpredictable characteristics of SVF, long-term follow-up is necessary.