Diabetes insipidus(DI) of central origin is a clinical syndrome resulting from low blood levels of antidiuretic hormone secreted from the posterior lobe of the pituitary gland, which is usually caused by lesions involving the hypothalamus-neurohypophyseal axis. MR imaging can reveal absence of the posterior pituitary bright signal(PPBS)in DI. The authors reviewed four patients with intracranial germinomas who had DI due to hypothalamus involvement. All patients before radiotherapy revealed absence of PPBS on MRI. Three cases recovered from DI after radiotherapy and showed reappearance of PPBS. Another one patients who continued DI didn't show signal change of the posterior pituitary gland. Ws speculated that the reappearance of PPBS is related to clinical improvement of DI.
Diabetes Insipidus* ; Follow-Up Studies* ; Germinoma* ; Humans ; Hypothalamus ; Magnetic Resonance Imaging ; Pituitary Gland ; Pituitary Gland, Posterior ; Radiotherapy*

We studied 21 neonates who required mechanical ventilation during study period in NICU OF Il Sin Christian Hospital with diagosis of prematurity, IRDS, pneumothorax and diaphragmatic hernia to evaluate the accuracy of pulse oximeter in predicting the arterial oxygen saturtion, hypoxia and hyperoxemia. We also studied whether the changes of birth weight, hematocrit, blood pressure and body temperature affect the accuracy of pulse oximeter. The results are 1) Linear regression analysis revealed a close correlation between in vivo pulse oximeter readings and in vitro SaO2 measurements in patients (Y=0.008X+12.34, r=0.946) 2) The changes of birth weight, hematocrit, blood pressure and body temperature did not affect the accuracy of pulse oximeter. 3) SpO2-PaO2 relationship was similar to the SsO2-PaO2 relationship. 4) When Nellcor N-100 pulse oximeter was setted at alarm limit 96% to avoid hyperoxemia, it identified 16 of 22 hyperoxemic instances (sensitivity 73%) and alarmed falsely in 48 of 92 nonhyperoxemic instances (specificity 59%).
Anoxia ; Birth Weight ; Blood Pressure ; Body Temperature ; Hematocrit ; Hernia, Diaphragmatic ; Humans ; Infant, Newborn ; Linear Models ; Oxygen* ; Pneumothorax ; Reading ; Respiration, Artificial

Proliferating trichilemmal tumor is one of rare benign tumors of the skin appendages, considering as hamartoma of the terminal hair follicle, isthmic segment of the outer root sheath. We report a case of numerous proliferating trichilemmal tumors admixed with ordinary trichilemmal cysts with femilial history in 64-year-old man. He has total 157 lesions, which are chiefly located in scalp (48), back (32), and also face, neck, trunk, extremities. Histologically, the tumor is composed of irregularly arranged and ansatomosed trabeculae, lobules, or sheets of proliferated trichilemmal squamous epithelium with peripheral palisading of the basaloid cells. Several layers of squamoid or ovoid cells have PAS-positive clear cytoplasm. And it also shows abrupt amorphous, trichilemmal keratinization. Some squamous eddies with mild cellular atypism are associated, but definite invasion or other evidence of the malignancy is not found. usual multiple trichilemmal cysts are admixed with tumor and occasionally exhibit connection between them.
Cysts ; Hamartoma

Lymphomatoid papulosis is an enigmatic disease entity which is clinically benign and histologically malignant. Although sporadic cases have been reported, we could not find any comprehensive report on the combined clinical and histologic features of lymphomatoid papulosis in the literature. Perhaps the most controversial aspect of lymphomatoid papulosis is its pathogenesis and categorization as a benign versus a malignant entity. To date, there are no reports on p53 and bcl-2 protein expression in lymphomatoid papulosis. We analysed the clinico-pathological findings of 18 cases with lymphomatoid papulosis during the 10 year period from 1984 to 1995 and examined the prevalence of immunoreactivity for CD30(DAKO, Ber-H2), p53(DAKO, DO-7), and bcl-2(DAKO, 124) using an immunohistochemical(ABC) method. The results obtained are summarized as follows. 1) Age distribution ranged from 20 to 65, with a mean age of 45 years and a sex distribution which showed a male predominence(8:1). The lesions were located on the trunk and extremities(8cases), extremities (7cases), and trunk(3 cases). The morphology of the lesions were papules or plaques(12 cases), and nodules(6 cases). 2) Histopathologic types were classified into 3 types: type A(4 cases), type B(8 cases) and mixed type (6 cases). 3) Positive immunoreactivity for CD30 was seen in 17%(3 of 18cases): type A(2 of 3) and mixed type(1 of 3). 4) The positive immunoreactivity for p53 and bcl-2 was observed in 29%(5 of 18) and 11%(2 of 18), respectively. 5) Cases showing positive immunoreactivity for P53 were type A(1 of 5), type B(1 of 5), and mixed type(3 of 5). 6) Cases showing positive immunoreactivity for bcl-2 were mixed type(2 of 2). One case developed into Ki-1 lymphoma. These results support the idea that lymphomatoid papulosis and Ki-1 lymphoma represent a continuum. The role of p53 gene mutation and bcl-2 activation in the development of lymphomatoid papulosis is currently unknown. But, our results suggest that p53 gene mutation and bcl-2 activation are not a critical step in the development of lymphomatoid papulosis. Further studies are needed to elucidate the role of p53 gene mutation and bcl-2 activation in the development and progression of lymphomatoid papulosis.
Male ; Humans ; Genes, p53

Cytophagic histiocytic panniculitis is a rescently described histiocytic disorder. It is characterized by the presence of fever, pancytopenia, and subcutaneous nodules resulting from the infiltration of lympho-histiocytes in the dermis and subcutaneous adipose tissue. The characteristic findings is presence of bean-bag histiocytes containing phagocytized red blood cells, lymphocytes, and platelets. We experienced two cases of cytophagic histiocytic panniculitis with hard and erythematous subcutaneous nodules. These skin lesions exhibited infiltration of the subcutaneous tissue by large, benign histiocytes with cytophagic features. Hemophagocytic histiocytes were observed in the cervical lymph node in case 1, and bone marrow in case 2. One patient is alive, while the other one died with hemorrhagic complications.

No abstract available.
Esophageal Atresia* ; Tracheoesophageal Fistula*

The purpose of this study is to find out the effects of personal characteristics and metamemory on the older adults' memory performances and the effects of some factors on metamemory. The subjects of the study consisted of 102 old adults over the age of 60 who are living in Kangwon Province. Based on contextual perspectives of the memory-aging theory and the previous foreign researches on memory, some data were collected by means of the interview method, using questionnaires for metamemory(MIA questionnaire by Dixon, et al., 1988), and depression(GDS by Yesavage and Sheikl, 1986). The other data were collected by the testing method on the memory performance such as the immeadiate word recall task, the delayed word recall task, the word recognition task(Elderly Verbal Learning Test by Kyung Mi Choi, 1998),and the face recognition task(Face Recognition Task tool developed by this study). The results of this study were as follows; 1. The level of metamemory is 3.4 points in the 5 point scale, the grades of the task and the achievement are relatively high and the grades of the change, the control, and the strategy are relatively low in the sub-concepts. 2. The significant variables to predict old adults' metamemory are depression level, age, sex, educational attainment and religious activity. 3. The strong variables to predict memory performances are memory knowledge, memory self-efficacy, age, religious activity. 4. The strategy, the achievement, the locus, and the change concept of the metamemory have high correlations with the immediate recall task, the delayed recall task, and the word recognition task. In conclusion, the enhancement strategies of metamemory and the support of social activities are independent fields for nursing intervention. Ultimately in this respect nurses' roles are very important in developing and performing some intervention programs for old adults' memory improvement, which have significant meanings in the field of nursing science.
Adult ; Depression ; Gangwon-do ; Humans ; Memory* ; Memory, Short-Term ; Nursing ; Verbal Learning ; Surveys and Questionnaires

No abstract available.
Humans ; Infant, Newborn*

The purpose of this study is to find out the effects of depression on older adults' metamemory and memory performances. The subjects of the study consisted of 103 older adults over the age of 60 who are living in Kangwon Province. Some data were collected by means of the interview method, using questionnaires for metamemory (MIA questionnaire by Hultsch, et al., 1988), and depression(GDS by Yesavage and Sheikl, 1986). Other data were collected by a testing method on the memory performance, such as the immediate word recall task, the delayed word recall task, the word recognition task(Elderly Verbal Learning Test by Kyung Mi Choi, 1998), and the face recognition task(Face Recognition Task tool developed by this study). The results of this study were as follows: 1) The average point of depressed older persons' metamemory is 3.2 on a 5 point scale and was significantly lower than nondepressed older persons' point of 3.6. Looking into each sub-concept of metamemory, depressed persons' points are higher in terms of task(4.1), but are lower in terms of change(2.3), locus(2.6), and strategy(2.9) in comparison with nondepressed persons' points. 2)Depressed older persons' memory performances are all significantly lower than nondepressed person's, especially in terms of face recognition task(t=7.26, p<.0082) and word recognition task(t=6.58, p<.01). 3) In both depressed and nondepressed persons, metamemory has a close correlation with all memory tasks. In particular, depressed older persons' correlation is higher across the board, especially in memory self-efficacy of metamemory(r=.36 - .49) in comparison with nondepressed persons. 4) According to the results of analysis on the relations between metamemory and memory performances of each memory task using canonical analysis, in the case of depressed older persons, strategy, locus, capability and task have high correlation with word recognition task and delayed word recall task. Also in the case of nondepressed persons, achievement, strategy, change and locus variable have high correlation with face recognition task and immediate word recall task. As mentioned above, depression variables have a negative effect on older persons' metamemory and memory performance. In conclusion, when we care for depressed older persons with less memory ability, we have to consider the outcomes of this study are relevant. In addition, it is necessary to develop nursing intervention in order to prevent memory loss and improve memory performance in depressed older persons.
Adult ; Depression* ; Gangwon-do ; Humans ; Memory Disorders ; Memory* ; Nursing ; Verbal Learning ; Surveys and Questionnaires

For the recovery of broken bone or the free vascularized bone graft the vascular topography of the nutrient artery is very important. To estabilish the metric data of the nutrient foramen, its number, direction and site had been observed, and the size and position were measured. The results are as follows. 1. In 53% of the femurs, the number of the nutrient foramen was two, and in 57.1% of the paired materials. The number in both side was not different. The femoral nutrient foramen opened toward the superior direction in the most cases (97.3%). The foramens appeared most commonly (58.9%) on the medial lip of the linea aspera of the femur. The positional index was variable between 28.6 to 70.0 and it was 46.4±10.7 in average. Foramina appeared most commonly (41.9%) in the 30-40 index area of total length of the femur. 2. The number of the tibial nutrient foramen was one in 91.0% of the cases. All of the foramen opened toward the inferior direction. The foramen was most commonly observed on the lateral to vertical ridge of thie tibia (74.3%). Dividing the fibular into 10 parts, the positional index of the tibia was variable between 14.5 and 55.4, and it was 33.4±4.7 in an average. In 85.3% of the cases, the foramen observed in 4th segment. 3. The number of the fibular nutrient foramen was one in the most cases (81.0%). The direction of the foramen was inferior in 88.0% of the cases. The foramen positioned on the posterior surface of the fiular and its average positional index was 47.9±11.3, and its range was 20.3 to 72.4. The foramen was observed in 5th segment in the most cases (35.9%). 4. The size of the nutrient foramen was measured by the various sized stylet. The diameter of the femoral nutrient foramen was ranged from 0.5mm below 1.0mm in 46.6% of the cases. The that of the tibia was ranged from 1.0mm below 1.5mm in 53.2% of the cases. And that of the fibular was ranged from 0.5mm below 1.0mm in 54.0% of the cases.
Adult* ; Arteries ; Femur ; Fractures, Bone ; Humans ; Lip ; Tibia ; Transplants