1.Comparison of IVF Outcomes in Patients with Endometriosis According to Severity.
Korean Journal of Fertility and Sterility 2006;33(4):219-227
OBJECTIVE: To evaluate the impact of endometriosis on IVF-ET cycles and to compare IVF outcomes between stage I/II and stage III/IV endometriosis. METHODS: We analyzed 697 patients (1,199 cycles) with endometriosis (stage I-II: 638 cycles, stage III-IV: 561 cycles) and 325 pts (459 cycles) with tubal factor as controls between January 1994 and April 2004. Pts with endometriosis were diagnosed by laparoscopy and medical and surgical treatment were done in 353 cycles (55.3%) and 466 cycles (83.1%) of stage I-II/stage III-IV endometriosis. Cycles with age>35 years or FSH>20 mIU/mL or severe male factor infertility were excluded. RESULTS: The number of retrieved oocytes (9.97+/-7.2 vs. 13.4+/-7.9 (p<0.0001)), total number of embryos (6.5+/-4.8 vs. 9.1+/-5.6 (p<0.0001)), and good quality embryos (2.43+/-1.6 vs. 2.74+/-1.7 (p=0.013)) significantly decreased in stage III-IV endometriosis than in control. But pregnancy rate of stage III-IV endometriosis was comparable with control (35.7% vs. 36.8%). Fertilization rate and number of total embryos were lower in stage I-II endometriosis than in control (64.8+/-22.9 vs. 70.8+/-20.8 (p<0.0001), 7.6+/-5.0 vs. 9.1+/-5.6 (p<0.0001)). In patients with medical and surgical treatment of endometriosis, pregnancy rate and live birth rate was significantly lower in stage I-II than in stage III-IV endometriosis (29.2 vs. 36.2 (%), p=0.045, 23.9 vs. 31.5 (%), p=0.043). There was no difference in the mean age, but the duration of infertility was significantly longer (56.5+/-26.3 vs. 46.9+/-25.8 (mon), p<0.0001) and fertilization rate was lower (64.7+/-23.3 vs. 70.5+/-22.7 (%), p=0.001) in stage I-II than stage III-IV endometriosis. CONCLUSION: We suggest that IVF should be considered earlier in patients with minimal to mild endometriosis because of significantly decreased fertilization rates.
Embryonic Structures
;
Endometriosis*
;
Female
;
Fertilization
;
Humans
;
Infertility
;
Laparoscopy
;
Live Birth
;
Male
;
Oocytes
;
Pregnancy Rate
2.Effects of 0.12% Chlorhexidine Gluconate on the Oral Hygiene of Endotracheal Intubation Patients at Intensive Care Units.
Jin Hee PARK ; Hye Soo LEE ; Jeong Soo KIM
Korean Journal of Nosocomial Infection Control 2012;17(2):79-86
BACKGROUND: This study tested the efficacy of 0.12% chlorhexidine gluconate for improving oral hygiene in intubated intensive care patients. METHODS: In a group of 57 ventilated patients, 29 received normal saline (NS) for oral hygiene, and 28 were treated with chlorhexidine gluconate (CHG). Data on oral bacterial colonization was collected for 11 months from October 2005 to August 2006. Tests of oral hygiene and oral microorganism culture were performed on the day of the ventilation, and repeated on days 4, 8, and 12. RESULTS: Oral hygiene was significantly improved in the CHG group compared to that in the NS group (P<.001). Further, all patients (100%) in the NS group tested positive for Staphylococcus aureus on the 12th day after the endotracheal intubation, whereas only 42.9% (P=0.026) of the CHG group were positive. The NS group also had higher isolation rates of Pseudomonas aeruginosa at 66.7% on the 8th day after intubation and 87.5% on the 12th day. At these same intervals, the CHG group had isolation rates of 29.4% (P=.028) and 14.3% (P=.010) respectively. CONCLUSION: The longer the period of endotracheal intubation, the more effective the 0.12% CHG treatment was for improved oral hygiene and reduction of S. aureus and P. aeruginosa colonization when compared to treatment with NS.
Chlorhexidine
;
Colon
;
Humans
;
Critical Care
;
Intensive Care Units
;
Intubation
;
Intubation, Intratracheal
;
Oral Hygiene
;
Pseudomonas aeruginosa
;
Sodium Chloride
;
Staphylococcus aureus
;
Ventilation
3.Study on the antibody formation in patinets treated with recombinant human growth hormone(rhGH).
Hye Jung JOO ; Duk Hi KIM ; Dong Soo KIM
Journal of the Korean Pediatric Society 1991;34(9):1261-1268
No abstract available.
Antibody Formation*
;
Humans*
4.A Case of Ocular Rosacea.
Hye Jin WOO ; Hye Nam LEE ; Sung Woo CHOI ; Chung Won KIM ; Man Soo KIM
Korean Journal of Dermatology 1999;37(3):400-403
Ocular rosacea is the eye manifestations of rosacea, which involves the lids, conjunctiva, and cornea. A recent study revealed that all patients with cutaneous rosacea had some degree of ocular involvement which is often undiagnosed. It is difficult to make a diagnosis of ocular rosacea because it lacks clinical or pathological hallmarks. However, early diagnosis and treatment are emphasized to decrease morbidity and prevent potential blindness. We report a case of ocular rosacea in a 49 year-old man who showed blepharoconjunctivitis, keratitis, and cutaneous manifestations of persistent erythema, telangiectasia, and papules. The ocular symptoms and signs had improved significantly with tetracycline therapy.
Blindness
;
Conjunctiva
;
Cornea
;
Diagnosis
;
Early Diagnosis
;
Erythema
;
Eye Manifestations
;
Humans
;
Keratitis
;
Middle Aged
;
Rosacea*
;
Telangiectasis
;
Tetracycline
5.A large cardiogenic thrombus lodged at the carotid bifurcation mimicking severe carotid stenosis
Min Jung Kim ; Da-Hye Jeong ; Hye-Hun Kang ; Soo-Kyoung Kim
Neurology Asia 2016;21(1):81-84
A 62-year-old woman without vascular risk factors presented with left-sided weakness and numbness.
Magnetic resonance imaging (MRI) brain depicted acute right hemispheric infarcts in the cortical and
subcortical white matter. Initial MR angiography (MRA) showed large thrombus at the right carotid
bifurcation. Valvular atrial fibrillation (vAF) with severe tricuspid regurgitation (TR) was found on
two-dimensional echocardiography. Serial follow-up computed tomography angiography (CTA) or
MRA at 3, 9, and 15 days after anticoagulation alone showed complete resolution of the thrombus
with no neurological deterioration. Our case suggests that prompt institution of anticoagulantion alone
may result in radiologic resolution of the thrombus with improvement in patient’s clinical status.
Carotid Arteries
6.Pulmonary Endometriosis: A case report.
Soo Jin JUNG ; Young Ju KIM ; Hye Kyoung YOON
Korean Journal of Pathology 1998;32(5):382-384
Pulmonary endometriosis is a rare disease which is characterized by hemoptysis during menstruation (catamenial hemoptysis). We report a case of pulmonary endometriosis in a 33-year-old housewife. She has had regular menses with moderate flow and minimal dysmenorrhea. She had undergone curettage in May 1995 for artificial abortion. In July 1995, she experienced the first episode of hemoptysis. A chest CT scan revealed a 2.0 1.0 cm sized ill-defined soft tissue density in the periphery of anterior segment of the left upper lobe with a surrounding irregular ground-glass opacity. A left upper lobectomy was done under the diagnosis of pulmonary endometriosis. Cut section of the resected lung showed a round red-brownish solid lesion, measuring 2.0x1.0cm in cross. Microscopically a focus of the endometrial tissue, which was composed of endometrial glands and stroma, was found in the lung parenchyme and many hemosiderin laden macrophages were seen in the surrounding alveoli. The postoperative course was favorable with no further episodes of hemoptysis.
Adult
;
Curettage
;
Diagnosis
;
Dysmenorrhea
;
Endometriosis*
;
Female
;
Hemoptysis
;
Hemosiderin
;
Humans
;
Lung
;
Macrophages
;
Menstruation
;
Rare Diseases
;
Tomography, X-Ray Computed
7.X-linked agammaglobulinemia.
Dal Sik KIM ; Mi Yae YOON ; Hye Soo LEE
Korean Journal of Clinical Pathology 1991;11(3):545-548
No abstract available.
Agammaglobulinemia*
8.The Clinical Significance of Squamous Cell Carcinoma Antigen as a Predictor of Nodal Metastasis in Early Stage Cervical Carcinoma.
Soo Mee PARK ; Hye Sung MOON ; Seung Cheol KIM
Korean Journal of Obstetrics and Gynecology 2000;43(3):380-385
OBJECTIVE: SCC-Ag(Squamous Cell Carcinoma Antigen) is a tumor marker for patients with squamous cell carcinoma of the uterine cervix. It has shown that the SCC-Ag was well related with the response of cancer therapy and course of cervical cancer. The aim of this study is to investigate whether the presence of pelvic lymph node metstasis can be predicted by the measurement of the preoperative SCC-Ag levels in the patients with early staged squamous cell carcinoma of cervix. METHODS: The preoperative serum SCC-Ag levels were measured in 45 patients with stage I-II squamous cell carcinoma of cervix undergoing radical hysterectomy from September 1995 to December 1997. The serum SCC-Ag levels were analyzed for the clinicopathologic characteristics and other prognostic factors using univariate and multivariate analysis. RESULTS: The serum SCC-Ag levels of the patients exhibited pelvic lymph node metastasis were above 4.8ng/ml. An elevated preoperative serum SCC-Ag level, and tumor size were independent predictors for the presence of lymph node metastasis(p<0.01). CONCLUSION: The determination of the preoperative serum SCC-Ag levels provides a new prognostic factor in early staged cervical cancer.
Carcinoma, Squamous Cell*
;
Cervix Uteri
;
Female
;
Humans
;
Hysterectomy
;
Lymph Nodes
;
Multivariate Analysis
;
Neoplasm Metastasis*
;
Uterine Cervical Neoplasms
9.HISTOPATHOLOGIC FINDINGS OF THE DEGENERATED INFERIOR ALVEOLAR NERVES RESECTED DUE TO REFRACTORY TRIGEMINAL NEURALGIA.
Myung Rae KIM ; Man Ho SUNG ; Hye Soo KOO
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):656-667
This is to report the histo-pathologic findings of the degenerated inferior alveolar nerves(IAN) causing uncontrollable neuralgia persisted for over 3 years. The patients had sufferred from frequent attack of unbearable pain along the mandibular branches of the Vth nerve. The pain arised spontaneously 5-10 times a day and lasted for 2-5 minutes. The medications including Tegretol were neither so effective to alleviate the pain level, nor enough to keep free from pain all days. The peripheral neurectomies were preceded by diagnostic nerve block, and partial resection of the IAN in the mandibular canals were approached by sagittal split osteomy of the ramus. The histopathologic findings of the resected IAN were as follows ; 1. Special staining with Luxol Fast Blue (LFB) and Masson Trichrome (MT) disclosed marked degeneration of the axons, decreased in number and fibrosis between the nerve fibers. 2. EM study revealed destruction of myelin continuity surrounding axons, degeneration of Schwann cell and endoneureal sheath, and coarse collagen between the destructed axons. 3. The 3 of 6 patients presented again with recurred pain in 2-3 years after the peripheral neurectomies. Excisional biopsy of the retromolarpterygomandibular softtissues disclosed the collateralization neuropathy beside the long-buccal nerves and their neuromatous findings.
Axons
;
Biopsy
;
Carbamazepine
;
Collagen
;
Fibrosis
;
Humans
;
Mandibular Nerve*
;
Myelin Sheath
;
Nerve Block
;
Nerve Fibers
;
Neuralgia
;
Trigeminal Neuralgia*
10.A case of delayed radiation-induced lumbosacral radiculoplexopathy after 30 years
Jinhyun Kim ; Hye Lim Lee ; Sang-Soo Lee
Neurology Asia 2015;20(3):297-299
Lumbosacral radiculoplexopathy in colon cancer treatment is a very rare but serious complication
after radiation. We report here a 66-year-old man with slowly progressive lower limb weakness which
arose 30 years after local radiation treatment for colon cancer. Electrophysiological studies revealed
signs of denervation confined to the lower limbs. Other causes were excluded by clinical presentation,
serological, cerebrospinal fluid and imaging studies. This case shows that delayed radiation-induced
lumbosacral radiculoplexopathy can occur 30 years after the initial treatment.
Colonic Neoplasms