2.PCR-RFLP patterns of four isolates of Trichinella for rDNA ITS1 region.
Hye Soo KWON ; Myung Sook CHUNG ; Kyoung Hwan JOO
The Korean Journal of Parasitology 2001;39(1):43-48
We have studied the genetic differences among four isolates of Trichinella including a new strain of Trichinella spiralis (ISS 623) recently found from a human case who took a badger in Korea. Because they have a different host origin and came from geographically separated regions, we supposed the genetic pattern of the isolates might be different as had been previously reported. It was analysed by PCR-RFLP analysis of the rDNA repeat that can readily distinguish a species or strain from others. Isolated genomic DNA of each isolate of Trichinella larvae was amplified with ITS1 specific primers and digested with restriction endonucleases. The PCR product of ITS1 was confirmed using Southern blot analysis to be a 910 bp fragment. The restriction fragments of each isolate had variable patterns when it was digested with Rsa 1 only. According to the RFLP patterns, the estimated genetic divergence between each isolate was different. In conclusion, four isolates of Trichinella including a new strain of T. spiralis obtained from a Korean patient may have genetic differences in the ITS1 region and the Shanghai isolate was genetically more similar to the Japanese unknown isolate than others in the ITS1 region.
Animals
;
*DNA, Helminth
;
*DNA, Ribosomal
;
Human
;
Polymerase Chain Reaction
;
Polymorphism, Restriction Fragment Length
;
Repetitive Sequences, Nucleic Acid
;
Trichinella spiralis/*genetics/isolation & purification
3.Heart size in new-born infants
Soo Won KIM ; Yun Jeong YU ; Hye Kyung CHUNG
Journal of the Korean Radiological Society 1985;21(5):751-754
Cardiac size of 291 new-born infants was measured using the method illustated on Fig 1. Among the 291 infants,53 were asphyxiated, and asphxia was only regared from Apgar score below 6 on 1 min. and 5 min. Remaining 238infants were normal, and classified to group with lung abnormalities and without lung abnormalities on chest A-Pfilm. The results are as follows; 1. The average CTR. of normal group was 52.37(C/T1;54.89, C/T2;49.43, C/T3;49.15, C/T;55.97) 2. The average CTR. of asphxiated group was 54.91 (C/T1;57.13, C/T2;51.69, C/T3;51.94,C/T4;58.25) 3. Consequently, asphyxiated infants revealed larger cardiac size than normal infant group.
Apgar Score
;
Heart
;
Humans
;
Infant
;
Lung
;
Methods
;
Thorax
4.A Case of Ocular Rosacea.
Hye Jin WOO ; Hye Nam LEE ; Sung Woo CHOI ; Chung Won KIM ; Man Soo KIM
Korean Journal of Dermatology 1999;37(3):400-403
Ocular rosacea is the eye manifestations of rosacea, which involves the lids, conjunctiva, and cornea. A recent study revealed that all patients with cutaneous rosacea had some degree of ocular involvement which is often undiagnosed. It is difficult to make a diagnosis of ocular rosacea because it lacks clinical or pathological hallmarks. However, early diagnosis and treatment are emphasized to decrease morbidity and prevent potential blindness. We report a case of ocular rosacea in a 49 year-old man who showed blepharoconjunctivitis, keratitis, and cutaneous manifestations of persistent erythema, telangiectasia, and papules. The ocular symptoms and signs had improved significantly with tetracycline therapy.
Blindness
;
Conjunctiva
;
Cornea
;
Diagnosis
;
Early Diagnosis
;
Erythema
;
Eye Manifestations
;
Humans
;
Keratitis
;
Middle Aged
;
Rosacea*
;
Telangiectasis
;
Tetracycline
5.Hypomatremia in children.
Youn Ok KIM ; Hye Li CHUNG ; Khun Soo LEE ; Ja Hoon KOO
Journal of the Korean Pediatric Society 1985;28(5):415-422
6.The psychological characteristics of functional dyspepsia patients by MMPI.
Keun Sang YUM ; Whan Seok CHOI ; Hye Seong PARK ; Byung Soo LEE ; Mee Ryoug CHUNG
Journal of the Korean Academy of Family Medicine 1997;18(6):666-674
BACKGROUND: The functional dyspepsia gives rise to such a symptom similar to peptic ulcer without showing a noticeable lesion(e.g, gastric or duodenal ulcer) by endoscopy or upper GI serises, and it has been known that this is about twice as many as the peptic ulcer. However, there is no exact theory about its pathophysiology and it is suggested that multiple factors including genetic, physiologic, psychologic, environmental factors are engaged. Especially, in respect to the occurrence of functional dyspepsia and psychological factors, there have been many clinical studies over the world. But, we still need more studies in this country, therefore, this study has been initiated to give help patients of functional dyspepsia, invest.igating their characteristic traits through MMPI. METHODS: From March to September in 1996, the patients who visited the family medicine out-patients department of St. Marys hospital of Catholic Medical College were sampled in this study. There were 46 patients having a similar symptoms to peptic ulcer without showing pathologic lesions by endoscopy. Through an interview and some basic tests, the 41 controls who had no dyspeptic symptoms and were not affected to a noticeable physical or physiological disorders were selected for the normal reference group. The standardized MMPI of our country was applied to the whole object groups to get a result. Then each average value of the measure(mean T-score) was calculated, and the differences of the average value were analyzed by the t-test and chi-square test. And the psychological pattern analysis was done. RESULTS: In demographic aspects, there were no significant differences between the two groups. The mean T score for each measure of the two groups falls within the normal ranges with their values being of between 30 to 70. And the average of L, F, and K measure, known as the validity measure, did not give a significant differences between the two groups. The measure of Hs, D, and Hy have appeared significantly high in the patients group(p<0.01) and the Pd measure, too(p<0.05). While Mf, Pa, and Ma measure have not shown a significant differences, Pt, Sc, and Si measure have very significant differences(p<0.01). CONCLUSIONS: In the patient group with the functional dyspepsia, the measures of Hs, D, and Hy where they indicate a neurotic pattern have shown a very significantly high point as well as those of Pd, Pt, Sc, and Si where they indicate a psychotic pattern. This reveals that in the group of the functional dyspepsia neurotic or psychotic trends to attribute. However, it is very hard to define the characteristics of a group with just one test, so further study with more variable test will be necessary.
Dyspepsia*
;
Endoscopy
;
Humans
;
MMPI*
;
Outpatients
;
Peptic Ulcer
;
Psychology
;
Reference Values
7.Primary Tracheobronchial Amyloidosis: A Case Report.
Ho Jung KIM ; Yul LEE ; Soo Young CHUNG ; Mi Sook WON ; Ik YANG ; Hye Kyung AHN
Journal of the Korean Radiological Society 1995;32(1):121-123
Localized pulmonary amyloidosis is a rare disease characterized by a deposition of amyloid limited to the lungs. We report a case of primary tracheobronchial amyloidosis which resulted in collapse of left lung and was confirmed by the Congo-red staining.
Amyloid
;
Amyloidosis*
;
Lung
;
Rare Diseases
8.Primary Tracheobronchial Amyloidosis: A Case Report.
Ho Jung KIM ; Yul LEE ; Soo Young CHUNG ; Mi Sook WON ; Ik YANG ; Hye Kyung AHN
Journal of the Korean Radiological Society 1995;32(1):121-123
Localized pulmonary amyloidosis is a rare disease characterized by a deposition of amyloid limited to the lungs. We report a case of primary tracheobronchial amyloidosis which resulted in collapse of left lung and was confirmed by the Congo-red staining.
Amyloid
;
Amyloidosis*
;
Lung
;
Rare Diseases
9.Anesthetic Management of a patient with Primary Aldosteronism caused by Adrenal Adenoma.
Kyung Hye CHOI ; Heung Kwan CHUNG ; Il Soo KYOUN
Korean Journal of Anesthesiology 1994;27(11):1692-1697
Increased and inappropriate production of aldosterone from the adrenal gland is known as primary aldosteronism and leads to sodium retention with hypertension, suppression of plasma renin, and hypokalemia and its manifestations. It is due mainly to a solitary adenoma, bilateral hyperplasia, or rarely an adrenal carcinoms. Primary aldosteronism due to an adenoma is usually treated by surgical excision. Preoper-ative managements include the correction of hypokalemia, volume derangement, and metabolic alkalosis with spironolactone and the trestment of existing hypertension. The authors report a case of unilateral adrenalectomy and anesthetic considerations during perioperative periods.
Adenoma*
;
Adrenal Glands
;
Adrenalectomy
;
Aldosterone
;
Alkalosis
;
Humans
;
Hyperaldosteronism*
;
Hyperplasia
;
Hypertension
;
Hypokalemia
;
Perioperative Period
;
Plasma
;
Renin
;
Sodium
;
Spironolactone
10.A Case of Familial Treacher-Collins Syndrome.
Sang Hee CHO ; Hye Sun CHUNG ; Gwi Jong CHOI ; Heung Jae LEE ; Keun Soo LEE
Journal of the Korean Pediatric Society 1983;26(12):1215-1219
No abstract available.