Neural tube defects are reported one of the important congenital malformation in the world, with an incidence of 1.4 to 2 per 1000 pregnancies. Maternal serum AFP at the second trimester is used as screening test. But this is associated with numerous causes, including twins, fetal death, misdated pregnancies, cystic hygromas, teratomas, renal abnormalities, esophageal atresia and aberrations in the placenta. If the AFP level was elevated, targeted ultrasonography should be evaluated for confirming the gestational age and fetal viability, fetal number. Then if the ultrasonographic examination is nondiagnostic, or if an NTD is suspected, amniotic fluid AFP should be measured with acetylcholinesterase. But the false positive rate of the AF-AFP is high, and there is 0.3% of the false positive rate in amniotic acetylcholinesterase. This time the women with normal ultrasonographic examination continue the pregnancy after counseling of family history, past history with follow up of ultrasonography. We report a case with elevated second trimester MS-AFP, AF-AFP and positive amniotic acetylcholinesterase, but in which repeated sonographic findings were normal and result in delivery of a healthy baby without anomalies.
Acetylcholinesterase* ; Amniotic Fluid ; Counseling ; Esophageal Atresia ; Female ; Fetal Death ; Fetal Viability ; Follow-Up Studies ; Gestational Age ; Humans ; Incidence ; Lymphangioma, Cystic ; Mass Screening ; Neural Tube Defects ; Placenta ; Pregnancy Trimester, Second ; Pregnancy* ; Teratoma ; Ultrasonography

With the number of long-term care facilities in Korea increasing substantially, their quality and evaluation system has been an issue of concern. Policy makers need to consider critical aspects relating to health outcomes and client satisfaction when evaluating quality in long-term care. This requires a substantial amount of information gathered from a system of inspection, survey, data, and feedback. This study reviews the characteristics of Online Survey Certification and Reporting system (OSCAR) and the survey instrument used by the Centers for Medicare and Medicaid Services (CMS) in the U.S. and introduces the history of the U.S. nursing home (NH) inspection/survey system. OSCAR is administered by state agencies that contract with CMS and collect data through onsite inspections of facilities approximately once per year. The major components of OSCAR data are facility characteristics, resident characteristics, and survey deficiencies including scope and severity. We discuss the strengths and weaknesses of OSCAR, the primary source of information on the performance of all Medicare/Medicaid certified facilities, including a comparison of resident health outcome evaluation measurement between Korea's assessment tool and OSCAR. Introduction of a data collection system that includes a periodic survey process similar to OSCAR may help policy makers gain a better understanding of the NH industry in Korea and address shortcomings of the system.
Administrative Personnel ; Centers for Medicare and Medicaid Services (U.S.) ; Certification ; Contracts ; Data Collection ; Humans ; Korea ; Long-Term Care ; Nursing Homes ; United States

No abstract available.
Keratitis*

Purpose: This study aimed to investigate the perceptions of precocious puberty and elucidate the distinct characteristics of each type of perception related to precocious puberty among school-aged children who had undergone treatment for the condition. Methods: This study applied the Q methodology to identify and classify the perceptions of precocious puberty among school-aged children who had undergone treatment for the condition. The analysis involved 34 questions from the Q sample and data from 35 individuals in the P sample, using the PC-QUANL Program for analysis. Results: The perceptions of precocious puberty among school-aged children who had undergone precocious puberty treatment were classified into the following four types: "shyness - passive self-management," "resentment - suppression," "anxiety - fear," and "adaptation - acceptance." Conclusion This study investigated the experiences and perceptions of children who have undergone treatment for precocious puberty. Through the identification of four types of perceptions, we can see that there is a need to develop an intervention program for nursing that is tailored to the specific type of precocious puberty.

No abstract available.
Epilepsy ; Humans ; Ophthalmoplegia

Intrathecal chemotherapy with methotrexate and cytarabine arabinoside is used for the treatment and prophylaxis of malignancies, but can induce myelopathy. We report the case of a 50-year-old woman with stomach cancer who developed myelopathy after administration of intrathecal cytarabine arabinoside and methotrexate. The patient's neurologic status improved rapidly after the administration of folinate (15 mg) four times daily and cyanocobalamin (100 mug) once daily. The folate metabolites may be effective in the management of intrathecal-chemotherapy-induced myelopathy.
Cytarabine ; Female ; Folic Acid ; Humans ; Methotrexate ; Middle Aged ; Spinal Cord Diseases ; Stomach Neoplasms ; Vitamin B 12

BACKGROUND: Liver transplantation (LT) is a complicated procedure with a high incidence of postoperative acute kidney injury (AKI). Previous studies indicate that even transient or mild post-LT AKI can result in critical conditions, including prolonged stays in hospitals and intensive care units and increased morbidity and mortality. The aim of this study was to investigate the association between body mass index (BMI) and occurrence of AKI in LT recipients. METHODS: Medical data from 203 patients who received LT surgery from January 2010 to August 2016 in a single university hospital setting were retrospectively collected and analyzed. Patients were classified as either underweight (BMI <20 kg/m²) or normal weight (20 ≤ BMI < 30 kg/m²). Demographic data, anesthetic methods, complications, and perioperative laboratory test values of each patient were assessed. Propensity analyses and logistic regression were performed to evaluate the association between BMI and post-LT AKI. RESULTS: There was no significant difference in occurrence of post-LT AKI between underweight and normal weight patients. The underweight patient group had significantly longer hospital stay compared with the normal weight patient group (P = 0.023). CONCLUSIONS: BMI classification was neither a positive nor negative predictor of postoperative AKI occurrence. However, patients with lower BMI had significantly longer hospital stay compared with their counterparts. Although our study was limited by its retrospective design, our observations suggest that lower BMI might play a role in post-LT AKI.
Acute Kidney Injury* ; Body Mass Index* ; Classification ; Humans ; Incidence ; Intensive Care Units ; Length of Stay ; Liver Transplantation* ; Liver* ; Logistic Models ; Mortality ; Retrospective Studies* ; Thinness

No abstract available.
Cervix Uteri* ; Female

BACKGROUND AND OBJECTIVES: Statin prevents atherosclerotic progression and helps to stabilize the plaque. According to a recent study, statin reduces inflammation in blood vessels. However, it has not been demonstrated to have any anti-inflammation reaction in patients who have been diagnosed as having a triple-vessel coronary artery disease (CAD). SUBJECTS AND METHODS: This study included a total of thirty (30) patients who had been diagnosed by coronary angiogram as having a triple-vessel CAD. Patients who already had been taking statin were given doubled dosage. An interview, physical examination and blood test were performed at the beginning of this study and three months later. RESULTS: After doubling the dose of statin, there was no statistically significant decrease in total cholesterol, low density lipoprotein-cholesterol, (increase in) high density lipoprotein-cholesterol and triglyceride in the blood test. C-reactive protein (CRP), an acute phase reactant, significantly decreased from 0.34 mg/dL at the beginning of the study to 0.12 mg/dL at the end of study (p<0.01). The interleukin-6 concentration also significantly decreased from 8.55 pg/dL to 4.81 pg/dL (p<0.001). No major cardiovascular events occurred and the dosage regimen was not modified during the close observation period. There was no difference in the symptoms of angina pectoris, established by World Health Organization Angina Questionnaires, before and after the dose increase. Liver enzymes remained within normal range with no significant increase before and after conducting this study. CONCLUSION: Doubling the dose of statin alone significantly lowers pro-inflammatory cytokine concentration, which is closely related to the potential acute coronary syndrome, and CRP, a marker of vascular inflammation.
Acute Coronary Syndrome ; Angina Pectoris ; Blood Vessels ; C-Reactive Protein ; Cholesterol ; Coronary Artery Disease ; Coronary Vessels ; Hematologic Tests ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Inflammation ; Interleukin-6 ; Liver ; Physical Examination ; Reference Values ; World Health Organization ; Surveys and Questionnaires

OBJECTIVES: This study examined the trend of press reports on mental illness in Korea to help set a desirable direction for future press reports on the subject. METHODS: This study adopted the method of semantic network analysis to analyze the trend of press reporting on mental illness in Korea. The study analyzed 1253 newspaper articles from 2016 to 2018 published by the five major Korean press: The Kyunghyang Shinmun, The Dong-A Ilbo, The Chosun Ilbo, The JoongAng Ilbo, and The Hankyoreh. RESULTS: The number of articles on mental illness is on the decline year by year, with 465 articles in 2016, 406 in 2017, and 382 in 2018. According to keyword analysis, the order of the words of the highest frequency is as follows: treatment (659), patients (486), mental health (466), incidents (436), and children and adolescents (413). In terms of the Degree Centrality, Closeness Centrality, and Betweenness Centrality, the following words are commonly ranked within the top 10 on the lists: treatment, children and adolescents, patient, mental health, depressive disorder, family, suicide, and counselling. CONCLUSION The press should pay more attention to mental illness, and its reporting should guarantee accuracy, objectivity, fairness, diversity, and social responsibility. In addition, reports on mental illness need to provide balanced health information, considering the readers, from basic information on mental illness to detailed treatment methods. Establishing reporting guidelines for mental illness would help reduce harm and prejudice related to mental illness and increase access to treatment.