PURPOSE: The purpose of this study was to identify the effects of nutritional education program (NEP) on nausea and vomiting, anorexia, food intake, and nutritional status among GI cancer patients undergoing chemotherapy. METHODS: A nonequivalent, non-synchronized posttest design was used. Study subjects were conveniently selected 30 patients (15 subjects for each group) who were undergoing chemotherapy. The subjects of the experimental group received NEP which consisted of 2 educations and 1 counselling while they were hospitalized, and telephone counselling with nutritional supports after discharge for four times. RESULTS: The score of anorexia was lower and the amount of food intake was higher in the experimental group than those of the control group. However, there were no significant differences in levels of nausea and vomiting, weight, hemoglobin, albumin, and total protein level between the experimental and the control group. CONCLUSION: The findings demonstrate that the NEP was effective in alleviating anorexia and improving subjective food intake of GI cancer patients undergoing chemotherapy. These findings suggest that NEP can be a useful nursing intervention for preventing nutritional disorders for patients with GI cancer after chemotherapy.
Anorexia ; Child ; Eating ; Hemoglobins ; Humans ; Nausea ; Nutrition Disorders ; Nutritional Status ; Nutritional Support ; Telephone ; Vomiting

PURPOSE: The purpose of the study was to understand and describe health-related experience of women with physical disabilities, using feminist qualitative approach. METHODS: Eight women with physical disabilities participated to the study. Their mean age was 43, ranging from 39 to 67 years old. The data were collected by individual in-depth interviews and all interviews were audio-taped and transcribed verbatim. The transcribed data were analyzed using traditional qualitative content analysis from a feminist perspective. RESULTS: Six major categories emerged from the data. Category 1: "Isolation and alienation from the world.", Category 2: "A distorted self-image of physically disabled body.", Category 3: "Difficulties due to a fixed gender role.", Category 4: "Constant suffering from chronic pain.", Category 5: "Health problems that they have to endure by themselves.", Category 6: "Sublimation through selfreliance." The results of the study show how Korean women with physical disabilities suffer from social stigma, indifferences, and discriminations and struggle to survive in these unfriendly surroundings. CONCLUSION: The results of the study would help health professionals in designing effective intervention to improve health and to empower women with physical disabilities by providing deep understanding and critical insights of those women.
Disabled Persons ; Emigrants and Immigrants ; Female ; Feminism ; Health Occupations ; Humans ; Qualitative Research ; Social Stigma ; Stress, Psychological

Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxynucleic acid(mtDNA). We identified a single guanine to adenine transition mutation in the mitochondrial DNA at nucleotide position 11778(Wallace mutation)in a 13 year old boy. To our knowldge, this is the first report confirming mtDNA mutation in Korea. This would be very helpful for the correct diagnosis of optic neuritis, optic neuropathy and optic atrophy of unknown etiology as well as for genetic counselling in the future.
Adenine ; Adolescent ; Diagnosis ; DNA, Mitochondrial ; Guanine ; Humans ; Korea ; Male ; Optic Atrophy ; Optic Atrophy, Hereditary, Leber* ; Optic Nerve Diseases ; Optic Neuritis

A 45-year-old Korean woman visited our hospital complaining of poor vision after carbon monoxide (CO) poisoning. We have confirmed the presence of a point mutation at position 11778 in the ND4 gene of mitochondrial DNA. This case suggests that CO poisoning may precipitate the clinical expression of Leber's hereditary optic neuropathy (LHON). To our knowledge, this would be the first case report of clinical expression of LHON precipitated by CO poisoning.
Carbon Monoxide/adverse effects ; Carbon Monoxide Poisoning/*complications ; DNA Damage ; DNA, Mitochondrial/genetics ; Female ; Humans ; Middle Aged ; Optic Atrophies, Hereditary/*etiology/genetics ; *Point Mutation ; Visual Acuity

Purpose: : This study aimed to identify the factors affecting the quality of life of lung transplant patients.Method : The participants were patients who received lung transplants at a general hospital in City Y. Data were collected through structured questionnaires from June 2023 to August 2023. General characteristics, lung transplantation-related characteristics, quality of life, functional disability, treatment compliance, social support, anxiety, and depression—were measured. For data analysis, hierarchical multiple regression was performed using SPSS/WIN 29.0. Results: : In the final model, quality of life was associated with income, self-help group attendance, functional disability, social support, treatment compliance, and anxiety and depression. Together, they explained 61.2% of the total variance in the results. Conclusion : Our findings suggest that improving lung transplant patients’ quality of life requires active intervention in stress management to perform treatment instructions well, a social support system that can help them financially, and encouraging and participating in social activities as patients.

Purpose: : This study investigated the occurrence of postoperative ileus and its related factors in patients after spinal surgery.
Methods: : After a retrospective review of data from patients who underwent spinal surgery at a single hospital located in Busan from 2012 through 2016, a total of 253 patients were included. The subjects were divided into non-ileus and ileus groups. We compared patient-, surgery-, and postoperative hematologicalrelated factors.
Results: : A total of 41 (16.2%) out of 253 patients experienced postoperative ileus. Data analysis revealed significant differences between the two groups in mean age (68.44 vs 60.50 years), occupation (9.8 vs 28.8%), cardiovascular comorbidity (63.4 vs 37.7%), approach of surgery (supine/prone: 29.3/70.7 vs 12.7/87.3%), duration of anesthesia (5.86 vs 4.43 hours), narcotic use (75.6 vs 56.6%), postoperative serum hemoglobin level (3 days: 10.81 vs 11.41 g/dL), postoperative serum protein (immediately/3 days: 5.30/5.43 vs 5.62/5.68 g/dL), postoperative albumin level (3 days: 3.17 vs 3.40 g/dL), postoperative C-reactive protein level (3 days: 11.44 vs 8.36 mg/dL), postoperative bed stabilization period (3.32 vs 2.50 days), and onset of bowel movement (2.59 vs 1.94 days). In multivariate logistic regression, age and time of anesthesia were independent risk factors of postoperative ileus.
Conclusion : To detect ileus after spinal surgery early, nurse education is needed with intensive screening on advanced age, surgery-related factors, and postoperative hematological indices.

Purpose: This study aimed to analyze the risk factors influencing intraoperative hypothermia in patients undergoing breast cancer surgery. Methods: Data were collected from 129 patients who underwent breast cancer surgery at a general hospital in City B from May 7 to November 14, 2024. The collected data were analyzed using SPSS/WIN 27 with an independent t-test, a χ 2 test ( χ 2 -test), and logistic regression analysis. Results: A total of 61 (47.3%) out of 129 patients experienced intraoperative hypothermia. According to the results of the logistic regression analysis, lower BMI (odds ratio [OR]=0.85, CI=0.74~0.98, p=.028), a total amount of IV fluid of ≥500 mL (odds ratio [OR]=4.47,CI=1.07~18.75, p=.041), a surgery duration of ≥120 minutes (odds ratio [OR]=4.10, CI=1.02~16.51, p=.047), and intraoperative hypotension (odds ratio [OR]=3.64, CI=1.22~10.86, p=.020) were associated with an increased risk of intraoperative hypothermia. Conclusion To prevent intraoperative hypothermia, continuous observation and nursing intervention are required for patients with low BMI or those expected to undergo prolonged surgery. The use of warm fluids during surgery and proper intraoperative blood pressure management is also recommended.

Purpose: This study aimed to analyze the risk factors influencing intraoperative hypothermia in patients undergoing breast cancer surgery. Methods: Data were collected from 129 patients who underwent breast cancer surgery at a general hospital in City B from May 7 to November 14, 2024. The collected data were analyzed using SPSS/WIN 27 with an independent t-test, a χ 2 test ( χ 2 -test), and logistic regression analysis. Results: A total of 61 (47.3%) out of 129 patients experienced intraoperative hypothermia. According to the results of the logistic regression analysis, lower BMI (odds ratio [OR]=0.85, CI=0.74~0.98, p=.028), a total amount of IV fluid of ≥500 mL (odds ratio [OR]=4.47,CI=1.07~18.75, p=.041), a surgery duration of ≥120 minutes (odds ratio [OR]=4.10, CI=1.02~16.51, p=.047), and intraoperative hypotension (odds ratio [OR]=3.64, CI=1.22~10.86, p=.020) were associated with an increased risk of intraoperative hypothermia. Conclusion To prevent intraoperative hypothermia, continuous observation and nursing intervention are required for patients with low BMI or those expected to undergo prolonged surgery. The use of warm fluids during surgery and proper intraoperative blood pressure management is also recommended.

Purpose: This study aimed to analyze the risk factors influencing intraoperative hypothermia in patients undergoing breast cancer surgery. Methods: Data were collected from 129 patients who underwent breast cancer surgery at a general hospital in City B from May 7 to November 14, 2024. The collected data were analyzed using SPSS/WIN 27 with an independent t-test, a χ 2 test ( χ 2 -test), and logistic regression analysis. Results: A total of 61 (47.3%) out of 129 patients experienced intraoperative hypothermia. According to the results of the logistic regression analysis, lower BMI (odds ratio [OR]=0.85, CI=0.74~0.98, p=.028), a total amount of IV fluid of ≥500 mL (odds ratio [OR]=4.47,CI=1.07~18.75, p=.041), a surgery duration of ≥120 minutes (odds ratio [OR]=4.10, CI=1.02~16.51, p=.047), and intraoperative hypotension (odds ratio [OR]=3.64, CI=1.22~10.86, p=.020) were associated with an increased risk of intraoperative hypothermia. Conclusion To prevent intraoperative hypothermia, continuous observation and nursing intervention are required for patients with low BMI or those expected to undergo prolonged surgery. The use of warm fluids during surgery and proper intraoperative blood pressure management is also recommended.

PURPOSE: This study investigated the possible relationship between viral infection and first trimester pregnancy loss. MATERIALS AND METHODS: A prospective study was performed on 51 gravidas with missed abortion, fetal anomaly, pre-term delivery, and full-tem delivery at Hanyang University Hospital. Enteroviruses were detected by semi-nested reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry in abortive tissues and placentas. Enterovirus serotypes were confirmed by genome sequencing. Herpesviruses were detected by PCR. RESULTS: Coxsackievirus B3 (CVB3) was detected in 8 of 14 missed abortion cases, 1 of 27 full-term cases, and none of the 9 pre-term cases. Coxsackievirus B1 (CVB1) was detected in an encephalocele case. Herpes simplex virus type 1 was found in 4 full-term cases, 3 pre-term cases, and none of the missed abortion cases. CONCLUSION: The prevalence of CVB3 was significantly higher in missed abortion cases compared to full-term or pre-term delivery cases. CVB infection may therefore be an important etiological agent of missed abortion.
Abortion, Missed/*etiology ; Adult ; Coxsackievirus Infections/complications/*diagnosis/virology ; Enterovirus B, Human/genetics/*isolation & purification ; Female ; Humans ; Immunohistochemistry ; Placenta/virology ; Pregnancy ; Pregnancy Complications, Infectious/*virology ; Pregnancy Trimester, First ; Prevalence ; Prospective Studies ; Republic of Korea ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Analysis, DNA ; Uterus/*virology