1.Cellular Schwannoma Arising in a Facial Nerve.
Mee JOO ; Hye Sung KIM ; Yun Kyung KANG ; Hye Kyung LEE ; Jae Young PARK
Korean Journal of Pathology 1997;31(7):688-691
Cellular schwaninoma is a variant of schwannoma, which is characterized by predominance of cellular Antoni A area, presence of mitotic activity, nuclear hyperchromasia, pleomorphism, and absence of Verocay body. These pathologic features often prompted a misdiagnosis of malignancy. However, the clinical outcome has indicated the benignity of the tumor. We have experienced a case of cellular schwannoma arising from right facial nerve with right hemifacial weakness and erosion of mastoid process. Grossly, it was a 3.5 x 3 cm sized and relatively well encapsulated mass with yellowish, friable cut surface. Microscopically, cellular growth with moderate cellular pleomorphism and some mitotic activity (5/40 HPFS, up to 2/HPF) were noted. Immunostaining for S-100 protein showed diffuse strong positive reaction.
Diagnostic Errors
;
Facial Nerve*
;
Mastoid
;
Neurilemmoma*
;
S100 Proteins
2.Clinical Value of Demonstration of Estrogen and Progesterone Receptors using Paraffin Wax Sections in Breast Carcinoma.
Hye Kyung AHN ; Yun Jung KIM ; Young Euy PARK
Korean Journal of Pathology 1996;30(2):89-93
This study aimed at assessing the usefulness of paraffin wax sections for demonstration of ER(estrogen receptor) and PR(progesterone receptor), using brief microwave processing rather than proteolytic predigestion. The receptor status of a breast cancer is often into consideration when planning treatment nowadays. As biochemical receptor assays require large amount of fresh tumor tissue and are not always available for all tumors, pathologists are now increasingly asked to provide a service for the assessment of the receptor status in tissue routine sections. Until recently, immunohistochemical demonstration of receptors was used in frozen sections. Therefore, routinely processed paraffin wax sections of 25 cases of breast carcinoma with known ER and PR concentrations, estimated by the standard DCC(dextran-coated charcoal) biochemical assay, were examined using the ABC immunoperoxidase technique. The results were assessed semiquantitably, using a five grade scoring system. Of the 25 cases examined, with DCC cutoff point being <10 fmol,71% and 75% in positivity of each ER, PR receptor is concordant. Statistic analysis demonstrates high relationship between scoring system of IH method and DCC value in ER (R=0.6061, p=0.001) and PR (R=0.5832, p=0.001). The IH method can provide easily assessed reliable positive information about ER, PR status of breast carcinoma using routinely processed paraffin wax sections.
Breast Neoplasms
3.Clinical Observation on Guillain-Barre Syndrome in Children.
Byung Ran YUN ; Hye Kyung HAN ; Yong Seung HWANG
Journal of the Korean Pediatric Society 1989;32(1):52-61
No abstract available.
Child*
;
Guillain-Barre Syndrome*
;
Humans
4.Tricuspid Regurgitation in Heart Diseases in Infants and Children.
Hye Kyung HAN ; Yong Soo YUN ; Chang Yee HONG
Korean Circulation Journal 1988;18(1):127-134
Doppler echocardiography was performed to evaluate the tricuspid regurgitation in 786 infants and children with heart disease. 3 Doppler methods were used. : The duration of systolic turbulence of tricuspid regurgitation in thr right atrium was evaluated by continuous wave Doppler method, the distance of systolic turbulence within right atrium from the tricuspid plane, by pulsed Doppler method and the retrograde systolic hepatic vein regurgitation, by color Doppler method. The following results were obtained. 1) Incidence of pan systolic tricuspid regurgitation in each disease were as follows. 68% of ECD, 66% of Ebstein's anomaly, 54% of pulmonary atresia, 50% of arrhythmia, 45% of ASD, 38% of TAPVR, 15% of VSD, 26% of TOF, 12% of PDA, 13% of normal children. 2) In about 90% of children with tricuspid regurgitation, hepatic vein regurgitation was detected by color Doppler echocardiography.
Arrhythmias, Cardiac
;
Child*
;
Ebstein Anomaly
;
Echocardiography, Doppler
;
Echocardiography, Doppler, Color
;
Heart Atria
;
Heart Diseases*
;
Heart*
;
Hepatic Veins
;
Humans
;
Incidence
;
Infant*
;
Pulmonary Atresia
;
Scimitar Syndrome
;
Tricuspid Valve Insufficiency*
5.A Case of Three-Dimensional Image Reconstruction of Pulmonary Venous Return .
Hye Kyung LEE ; Chang Hwi KIM ; Yun Seoup JUNG
Journal of the Korean Pediatric Cardiology Society 2000;4(1):78-80
A case of supracardiac type of total anomalous pulmonary venous return into the superior vena cava is reported which was successfully diagnosed using spiral CT and three-dimensional image reconstruction. Spiral CT with three-dimensional reconstruction is non-invasive method of visualizing the vascular system and in some instances can replace conventional angiography in pediatric patients.
Angiography
;
Humans
;
Imaging, Three-Dimensional*
;
Scimitar Syndrome
;
Tomography, Spiral Computed
;
Vena Cava, Superior
6.Heart size in new-born infants
Soo Won KIM ; Yun Jeong YU ; Hye Kyung CHUNG
Journal of the Korean Radiological Society 1985;21(5):751-754
Cardiac size of 291 new-born infants was measured using the method illustated on Fig 1. Among the 291 infants,53 were asphyxiated, and asphxia was only regared from Apgar score below 6 on 1 min. and 5 min. Remaining 238infants were normal, and classified to group with lung abnormalities and without lung abnormalities on chest A-Pfilm. The results are as follows; 1. The average CTR. of normal group was 52.37(C/T1;54.89, C/T2;49.43, C/T3;49.15, C/T;55.97) 2. The average CTR. of asphxiated group was 54.91 (C/T1;57.13, C/T2;51.69, C/T3;51.94,C/T4;58.25) 3. Consequently, asphyxiated infants revealed larger cardiac size than normal infant group.
Apgar Score
;
Heart
;
Humans
;
Infant
;
Lung
;
Methods
;
Thorax
7.Second trimester selective termination in a dizygotic twin pregnancy with discordancy for Down's syndrome: A case report.
Hye Sun JUN ; Suk Kyung KIM ; Joo Yun CHO ; Sook Hwan LEE ; Hye Kyung LEE ; Chung Woong KAY
Korean Journal of Obstetrics and Gynecology 2000;43(2):302-304
A 33-year-old-woman with twin pregnancy underwent genetic amniocentesis in our hospital at 16 weeks of gestation. Fetal chromosomal analysis showed 46,XY,inv(9) and 47,XX,+21. The affected twin was terminated by ultrasonographically guided intracardiac injection of 3 ml potassium chloride solution at 19 weeks of gestation. A healthy 2570 g male infant was born by cesarean section with Apgar scores of 8 and 9 at one and five minutes, respectively.
Amniocentesis
;
Cesarean Section
;
Down Syndrome*
;
Female
;
Humans
;
Infant
;
Male
;
Potassium Chloride
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnancy*
;
Pregnancy, Twin
;
Twins, Dizygotic*
8.Ectopic Paragonimiasis Presented as Multiple Colonic and Liver Masses.
Hye Sung KIM ; Young Soo LEE ; Yun Kyung KANG ; Hye Kyung LEE ; Jun Hee KIM ; Hyuk Sang LEE
Korean Journal of Pathology 1997;31(4):357-360
Ectopic paragonimiasis has been diagnosed in many organs such as the mesentery, ovary, pleura, central nervous system, subcutis and very rarely in the liver. However, simultaneous involvement of the colon and liver, which mimics colonic cancer with liver metastasis, is quite unusual, and to our knowledge has never been reported. Our case is a 63 year old woman who visited our hospital because of upper abdominal pain. Radiologically, space occupying lesions were detected in the transverse colon, mesocolon and left hepatic lobe. After the radical presection, they were proved to be an ectopic paragonimiasis forming multiple cavitary parasitic granulomas with Charcot-Leyden crystals and degenerating eggs.
Abdominal Pain
;
Central Nervous System
;
Colon*
;
Colon, Transverse
;
Colonic Neoplasms
;
Eggs
;
Female
;
Granuloma
;
Humans
;
Liver*
;
Mesentery
;
Mesocolon
;
Middle Aged
;
Neoplasm Metastasis
;
Ovary
;
Ovum
;
Paragonimiasis*
;
Pleura
9.Large Cell Neuroendocrine Carcinoma of the Lung 2 cases including one presented as an ovarian mass.
Yun Jung KIM ; Jung Weon SHIM ; Hye Kyung AHN ; Young Euy PARK
Korean Journal of Pathology 1997;31(3):257-262
Pulmonary tumors exhibiting neuroendocrine differentiation are classified as typical carcinoid, atypical carcinoid, and small cell lung carcinoma(SCLC). Travis et al. proposed a fourth category of large cell neuroendocrine carcinoma, which is characterized by light microscopic neuroendocrine appearance, cells of large size, polygonal shape, low nuclear cytoplasmic ratio, coarse nuclear chromatin, with prominent nucleoli high mitotic rate and frequent necrosis; and neuroendocrine features by immunohistochemistry or electron microscopy. High grade neuroendocrine carcinoma (LCAC-NE) revealed aggressive clinical course. We report two cases of neuroendocrine tumors of the lung characterized by a trabecular pattern of large pleomorphic cells with frequent mitoses and wide necrosis. The frequent metastatic sites of atypical carcinoid were liver, bone and brain. One of our case is presented, at first, as an ovarian mass, which shows multifocal rosettes and revealed metastasis from lung. Both cases expressed neuroendocrine differentiation by light microscopy and immunohistochemistry. However clinical neuroendocrine symptom were not present.
Brain
;
Carcinoid Tumor
;
Carcinoma, Neuroendocrine*
;
Chromatin
;
Cytoplasm
;
Female
;
Immunohistochemistry
;
Liver
;
Lung*
;
Microscopy
;
Microscopy, Electron
;
Mitosis
;
Necrosis
;
Neoplasm Metastasis
;
Neuroendocrine Tumors
;
Ovary
10.Tricuspid Regurgitation in Patients with Atrial Septal Defect.
Hye Kyung HAN ; Jae Il SOHN ; Yong Soo YUN ; Chang Yee HONG
Korean Circulation Journal 1988;18(3):411-417
We evaluated the accuracy of a noninvasive method for estimating right ventricular systolic pressures in patients with atrial septal defect and tricuspid regurgitation defected by two-dimensional and Doppler ultrasound. Of 54 patients with atrial septal defect, 24(44%) had jets of tricuspid regurgitation. By use of the maximum velocity(V) of the regurgitatant jet recorded by continuous wave Doppler ultrasound and the Bernoulli equation, we predicted right ventricular systolic pressure(RVP) calculated by the equation of RVP=4V2+10 proposed by Tei et al.The values correlated well with catheterization values(r=0.851, standerd error of estimate=4mmHg). In addition the relation between the Lt to Rt shunt amount and the severity of tricuspid regurgitation was assessed. The severity of tricuspid regurgitation graded on a four-pointscali by pulsed Doppler and two-dimensional echocardiography correlated with Qp/Qs ratio calculated by the Fick's method(p<0.05).
Catheterization
;
Catheters
;
Echocardiography
;
Heart Septal Defects, Atrial*
;
Humans
;
Tricuspid Valve Insufficiency*
;
Ultrasonography