No abstract available.
Humans* ; Incidence* ; Papilloma*

Human membranous nephropathy (MN) is morphologically characterized by subepithelial immune complex deposits and progressive thickening of glomerular basement membranes (GBM). Studies have suggested that the enhanced secretion of classical and novel type IV collagen chains in MN contributes to spike formation and the novel type IV collagen chain is particularly related to thickening of GBM. It is unclear whether the increased accumulation of extracellular matrix (ECM) proteins in GBM is due to the increased mRNA expression for type IV collagen in glomerular visceral epithelial cells (GECs). To answer this question, we analyzed seven renal biopsies of patients with idiopathic MN using in situ hybridization. In MN, the number of GECs expressing mRNA for alpha1(IV) collagen was 2.82+/-1.80/glomerular cross section (gcs), and the number expressing mRNA for alpha4(IV) collagen was 8.42+/-2.85/gcs. The number of GECs expressing mRNA for alpha4(IV) collagen was significantly larger than that of alpha1(IV) collagen mRNA. The expression of mRNA for these ECM proteins in normal controls was negligible. These results suggest that subepithelial immune complexes stimulate the gene expression of alpha1(IV) collagen and alpha4(IV) collagen in glomerular GECs which, in turn, increase the secretion of ECM proteins and contribute to the thickening of GBM in MN.
Antigen-Antibody Complex ; Biopsy ; Collagen ; Collagen Type IV* ; Extracellular Matrix ; Gene Expression ; Glomerular Basement Membrane ; Glomerulonephritis, Membranous* ; Humans* ; In Situ Hybridization ; Podocytes ; RNA, Messenger*

PURPOSE: This correlational study was performed to identify the impacts of maternal child rearing attitudes on the menstrual attitudes and the determinants of positive menstrual attitudes in female middle school students. METHODS: With convenience sampling, 198 middle school female students were recruited living in one major city and its surrounding areas in Korea. Data was collected using a self administered questionnaire including menstrual attitudes and maternal child rearing attitudes from April 1 to July 15, 2008. RESULTS: Among the Maternal child rearing attitudes, affectionate, achievement oriented and rational attitudes had positive correlations to a positive menstrual attitude, and an autonomous attitude had a negative correlation to a negative menstrual attitude. As determinants of positive menstrual attitudes, feeling of menarche, mother's response at first menstruation, and rational maternal child rearing attitudes were delineated and their explained variance for a positive menstrual attitude was 18.5%. There was no difference on menstrual attitudes by K clustering in terms of maternal child rearing attitudes. CONCLUSION: These results support the critical role of the mother. Especially desirable maternal child rearing attitudes in relation to a positive menstrual attitude would be affectionate, achievement oriented and rational for early adolescent girls. In further studies, considerations are needed for menstruation related education and research for early adolescents and active involvement of the mother & daughter together.
Adolescent ; Attitude to Health ; Child ; Child Rearing/*psychology ; Female ; Humans ; Menarche ; Menstruation/*psychology ; Mother-Child Relations ; Mothers/*psychology ; Questionnaires

No abstract available.
Female ; Gonadotropin-Releasing Hormone* ; Humans ; Leiomyoma* ; Single Person*

No abstract available.
Endometriosis* ; Female

A wide range of denomination has been used for inflammatory myofibroblastic tumor (IMT). IMT is not entirely homogeneous, even though it shows some overlapping histologic features such as haphazard proliferation of spindle cell and polymorphic chronic inflammatory cell infiltraion. The spindle cell is considered to be of myofibroblastic origin but follicular dendritic cell origin was reported recently. IMT is known as nonneoplastic, aberrant inflammatory response. However, IMT could show local invasion, recurrence, vascular invasion, and malignant transformation, and clonal characteristics and aneuploidy of IMT support the hypothesis that IMT may be a neoplastic process. In order to define the nature of spindle cell of IMT, immunohistochemical stains for smooth muscle actin (SMA), vimentin (VMT), lysozyme, S-100 protein, cytokeratin, CD21 were done. Additional immunohistochemical stains for MIB-1 for proliferating activity and LMP (latent membrane protein) for Epstein-Barr virus (EBV) were done. IMTs were composed of each 2 cases from lung, liver and lymph node and one case from common bile duct, maxillary sinus, bladder and thigh, and were histologically subclassified according to Coffin et al. Nine cases (90%) were positive for SMA and VMT, but no correlation between SMA and VMT immunoreactivity and histologic types was identified. Five cases (50%) were positive for lysozyme and S-100 protein, and histologic type III was negative for lysozyme and S-100 protein, and immunoreactivity for S-100 protein was different according to the histologic subtypes. All 11 cases were negative for CD21 and EBV LMP. MIB-1 labelling index was less than 1% in all cases. In summary, the spindle cell is regarded as myofibroblastic origin rather than follicular dendritic cell origin. Relationship with EBV is not clear, and negligible MIB-1 reaction suggests that IMT might have a good prognosis.
Actins ; Aneuploidy ; Coloring Agents ; Common Bile Duct ; Dendritic Cells, Follicular ; Herpesvirus 4, Human ; Immunohistochemistry ; Keratins ; Liver ; Lung ; Lymph Nodes ; Maxillary Sinus ; Membranes ; Muramidase ; Muscle, Smooth ; Myofibroblasts* ; Prognosis ; Recurrence ; S100 Proteins ; Thigh ; Urinary Bladder ; Vimentin

No abstract available.
Urinary Tract Infections* ; Urinary Tract*

Objectives: The aim of this study was to measure the presentism, intention of employment, selfefficacy, degree of exhaustion, and factors affecting presentism of clinical dental hygienists for use as basic data when developing measures to address presentism. Methods: A self-reported questionnaire was completed by 210 clinical dental hygienists from April 1 to June 30, 2020. Data were analyzed using SPSS 20.0. Independent t-test, one-way ANOVA, the Scheffé post-hoc test, and Pearson correlation analysis were applied, based on which a multiple regression analysis was conducted. Results: Dental hygienists scored 3.09 points in presenteeism. The variables that influenced clinical empowerment were job and career burnout, explaining 12.3% of the variance in scores among dental clinic hygienists. Conclusions As a result, clinical dental hygienists’ presentism is associated with clinical background and exhaustion, and exhaustion as the strongest influence. Therefore, in order to reduce the loss of clinical dental hygienists due to presentism, it is necessary to develop and apply health promotion programs that can manage clinical dental hygienists’ health problems early and to provide support in the organizational aspects of their work.

Objectives: The aim of this study was to measure the presentism, intention of employment, selfefficacy, degree of exhaustion, and factors affecting presentism of clinical dental hygienists for use as basic data when developing measures to address presentism. Methods: A self-reported questionnaire was completed by 210 clinical dental hygienists from April 1 to June 30, 2020. Data were analyzed using SPSS 20.0. Independent t-test, one-way ANOVA, the Scheffé post-hoc test, and Pearson correlation analysis were applied, based on which a multiple regression analysis was conducted. Results: Dental hygienists scored 3.09 points in presenteeism. The variables that influenced clinical empowerment were job and career burnout, explaining 12.3% of the variance in scores among dental clinic hygienists. Conclusions As a result, clinical dental hygienists’ presentism is associated with clinical background and exhaustion, and exhaustion as the strongest influence. Therefore, in order to reduce the loss of clinical dental hygienists due to presentism, it is necessary to develop and apply health promotion programs that can manage clinical dental hygienists’ health problems early and to provide support in the organizational aspects of their work.

No abstract available.
Case-Control Studies* ; Health Promotion* ; Risk Factors*