No abstract available.
Psoriasis

No abstract available.
Humans ; Infant, Newborn*

No abstract available.

BACKGROUNDS: Obstructive sleep apnea syndrome(OSA) can divided into two groups, positional (PP) and non-positional(NPP) obstructive sleep apnea syndrome, according to the body position while sleeping. In this study, we evaluated the differences of anthropometirc data and polysomnographic recordings between the two types of sleep apnea syndrome. MATERIALS: Fifty patients with OSA were divided two groups by Cartwright's criteria. The supine respiratory disturbance index (RDI) was at least two times higher than the lateral RDI in the PP group, and the supine RDI was less than twice the lateral RDI in the NPP group. This patients underwent standardized polysomnographic recordings. The anthropometirc data and polysomnographic data were analyzed, statistically. RESULTS: Of all 50 patients, 30% were found to be positional OSA. BMI was significantly higher in the PP group(p<0.05). Total sleep time was significantly longer in the PP group (350.6±46.0min, p<0.05). Sleep efficiency was high in the PP group(89.6± 6.4%, 85.6±9.9%, p<0.05). Deep sleep was significantly higher and light sleep was lower in the PP group than in the NPP group but no difference was observed in REM sleep between the two groups. Apnea index(AI) and RDI were significantly lower(17.0±10.6, 28.5±13.3, p<0.05) and mean arterial oxygen saturation was higher in the PP group(92.7 ±1.8%, p<0.05) than in the NPP group. CONCLUSION: Body position during sleep has a profound effect on the frequency and severity of breathing abnormalities in OSA patients. A polysomnographic evaluation for suspected OSA patients must include monitoring of the body position. Breathing function in OSA patients can be improved by controlling their obesity and through postural therapy.
Apnea ; Humans ; Obesity ; Oxygen ; Polysomnography ; Respiration ; Sleep Apnea Syndromes ; Sleep Apnea, Obstructive* ; Sleep, REM

BACKGROUND: Ischemic heart disease is the most common type of heart disease and an important cause of death in Korea. Among marketed anti-anginal medications, molsidomine, nicorandil, and trimetazidine are approved in Korea with unique mechanism of actions. As these drugs are not approved by the US Food and Drug Administration, the access to the up-to-dated and comprehensive safety-related information has been less than optimal from drug information resources used by Korean pharmacists. METHODS: A systematic review was conducted using Embase and Korean manuscripts to compile safety updates for these medications. Out of 418 articles from keyword searches, 52 studies were reviewed in full to compare adverse effects (AEs) with the approved package inserts (PI). RESULTS: Molsidomine related adverse effects were mostly mild or moderate, but anxiety, palpitation, epigastric pain, and sexual potency reduction were additional AEs found from the review not listed in PI. Although PI has included ulceration in oral cavity and gastrointestinal tracts including anus by nicorandil, the Korea FDA recently recommended adding corneal, genital, and skin ulcers to the approved PI. Trimetazidine induced Parkinsonism, worsening of the symptoms for patients diagnosed with Parkinson's disease, gastrointestinal burning, and muscle cramps were additionally identified AEs not listed in PI for trimetazidine. CONCLUSION: Continuous evaluations of the safety profile of these agents are needed to balance the risks and benefits to provide evidence-based safety counseling to the patients. In addition, more focused efforts on spontaneous reporting are warranted by healthcare professionals to safeguard patients against AEs.
Anal Canal ; Anxiety ; Burns ; Cause of Death ; Counseling ; Delivery of Health Care ; Gastrointestinal Tract ; Heart Diseases ; Humans ; Korea ; Molsidomine* ; Mouth ; Muscle Cramp ; Myocardial Ischemia ; Nicorandil* ; Parkinson Disease ; Parkinsonian Disorders ; Pharmacists ; Product Labeling ; Risk Assessment ; Skin Ulcer ; Trimetazidine* ; Ulcer ; United States Food and Drug Administration

No abstract available.
Estradiol* ; Female ; Pregnancy ; Pregnancy* ; Pregnancy, Ectopic* ; Progesterone*

No abstract available.
Heart Septal Defects, Ventricular ; Jacobsen Distal 11q Deletion Syndrome* ; Pyloric Stenosis, Hypertrophic

OBJECTIVES: This study investigated the effects of Emotionally Focused Therapy (EFT) on distressed married couples. METHODS: We conducted 5 to 19 EFT sessions once a week with 10 couples from Yongin Mental Hospital who were experiencing marital conflict. We assessed participants before and after EFT, using the Beck Depression Inventory (BDI), Symptom Checklist 90-R (SCL-90R), and Korean Marital Satisfaction Inventory (K-MSI). The EFT consisted of 3 stages comprising 9 steps. Every couple followed this EFT structure. RESULTS: After completing the EFT sessions, the inventories showed the couples experiencing significant improvements in various psychological symptoms and marital satisfactions. CONCLUSION: These results indicate that EFT could be applied to distressed couples in a clinical setting and could effectively reduce psychological symptoms and improve marital satisfaction. Further study of the generalizability of these results and of the process variables are needed.
Checklist ; Depression ; Equipment and Supplies ; Family Characteristics ; Family Conflict ; Hospitals, Psychiatric ; Pilot Projects

This study was attempted to individualize upper and lower incisor position appropriate to individual characteristic dento-facial pattern. Lateral cephalometric radiographs of 75 Korean adults with normal occlusion and good facial profile whose ages were over 17 years were traced, digitized, and statistically analysed. The results of this study were as follows; 1. All cephalometric measurements of inciso, position and dento-facial pattern for normal occlusion showed wide range of variation. 2. There were no significant differences of incisor position between males and females. 3. Lower incisor position was highly correlated with ANB, N-A-Pog and SN/Mand. pl. angle and upper incisor position, with ANB, N-A-Pog and SN/Occ. pl. angle. 4. Multiple regression equations were established to individualize incisor position appropriate to individual characteristic dento-facial pattern. ANB and N-A-Pog angle were selected as the significant guiding variables affecting upper and lower incisor position. 5. Lower incisor position such as 1 to SN, 1 to occlusal plane and 1 to NPog(mm) and upper incisor position such as 1 to SN, 1 to palatal plane, 1 to NA, 1 to NA (mm) and 1 to NPog(mm) could be highly predicted from the variables of dento-facial pattern.
Adult ; Dental Occlusion ; Female ; Humans ; Incisor* ; Male

No abstract available.
Acinar Cells* ; Biopsy, Fine-Needle* ; Carcinoma, Acinar Cell* ; Parotid Gland*