OBJECTIVES: This study intended to determine significant factors that influence the health-related quality of life ("HRQoL"; EuroQol 5 Dimension health-related quality of life (EQ_5D) & EuroQol visual analogue scale (EQ_VAS)) of the elderly in Korea. METHODS: This study was based on 3,903 subjects aged 65 years or more who participated in the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V), 2010~2012. The HRQoL was analyzed by various factors (general characteristics, health habits, mental health, chronic diseases, nutrient intakes). SPSS statistics for complex samples (Windows ver. 21.0) was used. RESULTS: The HRQoL was higher in the males, those with higher educational level or higher income level while it was lower in those belong to single households. In particular, the EQ_5D was significantly higher in the group who reported walking practice, moderate physical activity (male), and the group who reported no vigorous physical activity (female). The EQ_VAS was significantly higher in the group who reported walking practice. Both EQ_5D and EQ_VAS were significantly lower in the group with stress, melancholy, suicidal thinking, and osteoarthritis. EQ_5D was significantly lower in the group with < 75% Estimated Energy Requirements (EER) in energy intake, and with < Estimated Average Requirements (EAR) in iron or niacin intake. A stepwise regression analysis revealed that i) higher educational level (male), and good self-rated health status significantly increased the EQ_5D, ii) age, alcohol intake (male), melancholy (female), suicidal thinking, osteoarthritis, and niacin intake deficiency (male) significantly decreased the EQ_5D, iii) higher income level (male) and good self-rated health status significantly increased the EQ_VAS, and iv) age (male), stress, suicidal thinking (female) and osteoarthritis significantly decreased the EQ_VAS. CONCLUSIONS: This study suggested that general characteristics, mental health, osteoarthritis, and niacin intake were associated with the HRQoL. Prospective research of long-term control is needed to establish the causal relationship between factors and the HRQoL.
Aged* ; Chronic Disease* ; Energy Intake ; Family Characteristics ; Humans ; Iron ; Korea ; Male ; Mental Health* ; Motor Activity ; Niacin ; Nutrition Surveys* ; Osteoarthritis ; Quality of Life* ; Thinking ; Walking

No abstract available.
Neuralgia, Postherpetic*

The activity and growth of the accessory male sex gland depend on the androgen. The sex hormones effect on the growth of seminal vesicle and the prostate differently, but the relationship of the age and hormonal effect is not clear. To clarify the ageing effect on the male sex accessory gland, the morphometrical study has been done and the results analyzed with hormonal effect on the gland structure. Twenty-five seminal vesicle and prostate on bloc autopsy specimens[aged 22-68] were used. Middle portion of each side of the seminal vesicle and all blocks of the prostate horizontally divided at 3-5mm were embbeded in paraffin. Serial 7microm thick sections were prepared with hematoxiline and eosin, Gomori trichrome staining. For quantification, the image analyzer and the point counting method were used. There was not noticable change in the ratio of the parenchyma and the fibromuscular stroma in prostate until age of 60. At age of 20s, the actual ratio of the central, peripheral and transitional zone was accounted to 25%, 70%, 5% respectively, and it changed to 25%, 62%, 13% at 50`s. The percentage of the epithelial component in the glandual tissue was higher in the seminal vesicle. In the prostate, that was highest in the central zone. Stromal component was most abundant in the transitional zone. In both glands, the epithelial percentage decreased while the stromal percentage increased with age. The changing rate of the epitheilal and stromal compoenent was highest in the central zone. The luminal component changed only in the peripheral zone. The stromal component was most abundent in the transitional zone at all ages, even the increasing rate was highest in the central zone. The change in the proportion of each prostate zone and the different pattern of tissue compositional change in seminal vesicle and each prostate zone according to age represent the difference of hormonal and ageing effects on the seminal vesicle and each prostate zone.
Autopsy ; Eosine Yellowish-(YS) ; Gonadal Steroid Hormones ; Hematoxylin ; Humans* ; Male ; Paraffin ; Phenobarbital ; Prostate ; Seminal Vesicles

No abstract available.
Immunoglobulin E*

No abstract available.
Leg*

A morphometric study on the trigeminal ganglion and the intracranial portion of the ophthalmic, maxillary and mandibular nerves was done in 50 Korean adult cadavers. The shape of the ganglion was classified into 7 types and semicircular shape was most common (54%). Mean width of the trigeminal root at porus trieminus was 6.08mm. The length of the trigemnal root from porus to the trigeminal ganglion was 8.28mm at ophthalmic portion, 10.16mm at maxillary portion, and 8.90mm at mendibular portion. Maximum width of the ganglion was 15.48mm and the breadth of the ophthalmic, and maxillary portion were 5.25mm and 5.26mm, respectively, and that of the mandibular portion (4.92mm) was narrow than the other portion. Intracranial ophthalmic nerve was 4.30mm of width and 17.89mm of length, and this nerve inclined average 39.7。 (range 14.56。) from sagital plane. It was observed infrequently that the cavernous sinus extended to the lateral border of the maxillary nervw and the emissary sinus ran under the mandibular nerve.
Adult* ; Cadaver ; Cavernous Sinus ; Ganglion Cysts ; Humans ; Mandibular Nerve* ; Ophthalmic Nerve ; Trigeminal Ganglion*

Rett syndrome is a newly characterized developmental disorder that affect girls exclusively. These girls are born clinically normal, but their psychomotor development stagnates and deteriorates between the age of 6 months and 2 1/2 years. The full syndrome comprises; aquired microcephaly, severe dementia, autism, loss of purposeful use of the hands, characteristic hand-wringing stereotypies, jerky ataxia of the trunk, epilepsy with various types of fits, and in later years spastic and trophic changes of the lower limbs. There is no known cytogenetic, biochemical or molecular marker for the disorder; the diagnosis is based on clinical criteria. We report a case of Rett syndrome with a brief review of related literatues.
Ataxia ; Autistic Disorder ; Cytogenetics ; Dementia ; Diagnosis ; Epilepsy ; Female ; Hand ; Humans ; Lower Extremity ; Microcephaly ; Muscle Spasticity ; Rett Syndrome*

No abstract available.
Mass Screening*

No abstract available.
DNA Nucleotidylexotransferase*

The composition and the structure of the sacrum present the sexual and the racial difference. The variation of the structure is meaningful in the administration of caudal anesthesia which used one of the safest and the most valuable means of local anesthesia. In this study, a morphological investigation of the sacrum in Korean adults was done using 145 dry sacral bones. Non-metrical morphological variations were observed and ten measurements were undertaken. The results of the study were as follows. 1. The five segmented sacrum appeared most commonly (62.1%). Six segmented sacrum appeared 37.2% and the incidence tended to increse according to the age. Four segmented sacrum was noted in one case (0.7%). 2. In 9.7%, deficiences existed in the upper dorsal wall of the sacral canal. In 5.5%, deficiences existed in the middle of the dorsal wall of the sacral canal. 3. The apex of the sacral hiatus was found mostly (28.9%) at the upper third of the body of fifth sacral vertebra. 4. The sacral hiatus was classified into five groups by shape with triangular being the most frequent. 5. There was a significant sexual difference in the antero-posterior and transverse diameters of the first sacral vertebral body, the length of the sacrum, and the length of the sacral hiatus. 6. The average sacral index I was 98.2 in male, and 104.4 in female. Sacral index I was the relationship between the greaster breath to the length of the sacrum. 7. The average sacral index II was 46.6 in male, and 44.8 in female. Sacral index II was the relationship between the first sacral body diameter to the greaster breath of the sacrum. A thorough knowledge of the anatomical features of the dorsum of the sacrum including above results will lead to the decrease in the number of failures in administration of caudal anesthesia.
Adult* ; Anesthesia, Caudal ; Anesthesia, Local ; Female ; Humans ; Incidence ; Male ; Sacrum* ; Spine