1.Juvenile Granulosa Cell Tumor of the Ovary: Report of a Case of Malignant Form with Unusual Pleomorphism.
Chong Jai KIM ; Jin Suk SUH ; Sung Hye PARK ; Je G CHI
Korean Journal of Pathology 1990;24(3):316-320
A case of Juvenile Granulosa Cell Tumor (JGCT) of the ovary with unusual pleomorphic histologic and malignant biologic behaviour is described. The tumor occurred in a 10-year-old girl and was associated with clinical features of isosexual pseudoprecosity and a marked elevation of serum estradiol. The mass manifested initially in the right ovary and subsequently involved the contralateral ovary. A multi-organ metastasis developed during a 6-month-interval despite chemotherapy. She received two operations at 6-month interval, and tissues were obtained from the tumor mass. A marked histologic difference was observed between these two samples. The second biopsy showed profound cellular pleomorphism with numerous multinucleated tumor giant cell formation and hyaline bodies. The differential diagnosis from germ cell tumor and the possible factors for the pleomorphism are discussed.
Diagnosis, Differential
;
Biopsy
;
Neoplasm Metastasis
2.Effects of Propofol Anesthesia on Local Cerebral Glucose Utilization and Cerebral Blood Flow in Rat.
Korean Journal of Anesthesiology 1989;22(4):497-505
The influence of Propofol on regional cerebral function and CBF were studied using 24 male Spragus-Dawley rat by quantitative autoradiographic technique for glucose ( (14C)deoxyglucose) and (14C) Iodoantipyrine. Rats had both femoral artery and vein cannulated and were placed on lead weight. Propofol was infused intravenously at a rate of 0.35 mg/kg/min. for induction and 0.3 mg/kg/min for maintenance untill loss of corneal reflex with stable vital signs. Local cerebral glucose utilization and CBF were checked from conscious control rats and propofol anesthetized rats. The results were as follows; 1) There was no physiologically significant effect of propofol on body temperature, MAP, PaCO, and pH. 2) Regional cerebral glucose utilization was markedly decreased in many, but not all, cerebral structures. 3) The order of decreased glucose utilization was Diencephalone>Telencephalone>Mesence-phalone>Mylencephalone. which means the forebrain was more affected than hindbrain. 4) The most affected area of glucose utilization were cerebral association area, visual system and sensory motor cortex, but the auditory system was not so much affected. 5) During combined use of N,O and propofol, there was no significant stimulation effect of N,O to propofol in glucose utilization. 6) Regional CBF were markedly decreased in many brain regions which means low local cerebral glucose utilization with low CBF. 7) Propofol has specific effect of lowering cerebral metabolic rate, CBF, and intracranial pressure but no signigicant effect on cardiovascular system, pulmonary system, or temperature.
Anesthesia*
;
Animals
;
Body Temperature
;
Brain
;
Cardiovascular System
;
Femoral Artery
;
Glucose*
;
Humans
;
Hydrogen-Ion Concentration
;
Intracranial Pressure
;
Male
;
Motor Cortex
;
Propofol*
;
Prosencephalon
;
Rats*
;
Reflex
;
Rhombencephalon
;
Veins
;
Vital Signs
3.A Clinical Study on Reye's Syndrome.
Hye Sun JUNG ; Seong Ryong HYON ; Ha Baik LEE ; Soo Jee MOON ; Chong Moo PARK
Journal of the Korean Pediatric Society 1985;28(8):783-794
No abstract available.
Reye Syndrome*
4.Placental Metastais of Maternal Gastric Adenocarcinoma: A case report.
Hye Seung LEE ; Young Ah KIM ; Chong Jai KIM ; Je Geun CHI
Korean Journal of Pathology 1999;33(3):214-216
Metastasis of a maternal neoplasm to the products of conception is extremely rare. About 50% of the reported cases were not examined grossly or had no grossly visible tumor deposit. A case of placental micrometastasis of gastric adenocarcinoma in a 28-year-old woman is presented. Artificial termination was performed in 22 weeks of gestation and a female fetus weighing 440 gm was delivered. The placenta weighed 220 gm and was grossly normal. Microscopic examination revealed a small number of micrometastasis scattered in the intervillous space.
Adenocarcinoma*
;
Adult
;
Female
;
Fertilization
;
Fetus
;
Humans
;
Neoplasm Metastasis
;
Neoplasm Micrometastasis
;
Placenta
;
Pregnancy
;
Stomach
5.A Case of Acute Megakaryoblastic Leukemia.
Hye Sun JUNG ; Ha Baik LEE ; Hahng LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1985;28(4):390-395
No abstract available.
Leukemia, Megakaryoblastic, Acute*
6.Cutaneous Cytomegalovirus Infection Presenting as Papules and Pustules in a Patient with Acquired Immunodeficiency Syndrome.
Heun Joo LEE ; Ji Hye PARK ; Chong Won CHOI ; Ga Young LEE ; Won Serk KIM
Korean Journal of Dermatology 2012;50(12):1089-1090
No abstract available.
Acquired Immunodeficiency Syndrome
;
Cytomegalovirus
;
Cytomegalovirus Infections
;
Humans
7.Hemolytic uremic syndrome with mycoplasma infection.
Hye Jung JOO ; Kyung Chong YU ; Keum Jeon KIM ; Ki Soo PAI ; Jae Seung LEE
Korean Journal of Nephrology 1991;10(2):216-223
No abstract available.
Hemolytic-Uremic Syndrome*
;
Mycoplasma Infections*
;
Mycoplasma*
8.A Study on the Clinical and Histopathological Findings in Patients with Mucocele.
Hong Zoon JANG ; Hye Rim PARK ; Kyu Joong AHN ; Jong Min KIM ; Chong Ju LEE
Korean Journal of Dermatology 1990;28(6):747-757
Mucoceles usually occur as solitary, asymptomatic, translucent, and dome-shaped cysts containing clear viscous fluid on lower lip or oral mucosa. The authors reviewed the clinical and histopathological findings in 33 patients with mucocele and attempted to clarify the difference between the histopathologic types (retention and extravasation). The results were summarized as follows. 1. Age distribution was from 2 to 53 years and mean age was 21.4 years. Male to female ratio was 1.2:1(18 males.15 females). 2. Histopathologic type was classified. 4 cases(12.1%, mean age.17.3 years) were retention type, 19 cases(57.6%, mean age.'21.5 years) mixed type, and 10 cases(30.3 %, mean age.20.9 years) extravasation type. Among 19 mixed types, 13 cases were retention dominant and 6 cases extravasation dominant. 3. Durations from the onset to the diagnosis could be clarified in 16 cases. Those were below 1 year in 14 cases(87.5% ) and below 3 years in 16 cases all. Mean duration was 9.4 months. 4. The sites of involvement were lower lip(72.7%), tongue(24.3%), and oral mucosa(3.0%), in decreasing order of frequency. 5. The visited departments were otolaryngology(72.7%), dentistry(12.1%), plastic surgery(9,1%) and dermatology(6.1%), in decreasing order of frequency. 6. In the histopathologic observation, surface epithelium was observed in 25 cases (75.8%), cyst in 23 cases(69.7%), granlation tissue in 29 cases(87.9%), mucin in 28 cases(84.8%), surrounding salivary glands in 20 cases(60.6%) and foamy macrophages in 32 cases(97.0% ), 7. Special stains(PAS, D-PAS, and alcian blue at pH2.5 and 0.4) for the mucin were performed in 10 cases. The results were compatible with sialomucin.
Age Distribution
;
Alcian Blue
;
Diagnosis
;
Epithelium
;
Female
;
Humans
;
Lip
;
Macrophages
;
Male
;
Mouth Mucosa
;
Mucins
;
Mucocele*
;
Salivary Glands
;
Sialomucins
9.A Case of Disseminated Herpes Zoster Associated with Herpetic Folliculitis.
Hyun Min SEO ; Ji Hye PARK ; Chong Won CHOI ; Ga Young LEE ; Won Serk KIM
Korean Journal of Dermatology 2013;51(2):163-165
No abstract available.
Folliculitis
;
Herpes Zoster
;
Herpesvirus 3, Human
10.Holoacardius Hemisomus Acephalus: A case report.
Tae Jin KIM ; Chong Jai KIM ; Sung Hye PARK ; Suk Keun LEE ; Je G CHI
Korean Journal of Pathology 1989;23(4):487-489
An autopsy case of holoacardius hemisomus acephalus is reported. She weighed 2,190 gm and the height was 38 cm. The head and upper extremities were absent, while the vertebrae and lower extremities were relatively well developed, but severely edematous. The heart, lungs, stomach, liver, spleen, and pancreas were missing, but the lower abdominal organs including kidneys, adrenal, urinary bladder, and genital organs were present. The intestine was blind-ended at jejunal level but opened into a normal anus. The umbilical cord had two arteries and one vein.