No abstract available.

No abstract available.

No abstract available.
Tomography, X-Ray Computed* ; Ultrasonography*

OBJECTIVE: In the development of squamous neoplasia of the uterine cervix, high risk HPV infection has been followed by CD44 variant expression and angiogenesis. The aim of this study is to evaluate the sequential changes and relatianship of CD44 variant expression, microvessel density (MVD), and VEGF expression in CIN III, microinvasive (MI) and invasive (CA) squamous cell carcinoma. METHODS: The materials were 17 cases of CIN III, 14 cases of MI and 15 cases of CA. In situ PCR for HPV 16/18 and immunohistochemical studies for CD44std, v6, v7/8, CD 31 for MVD, and VEGF were performed. RESULTS: CD44std expression was decreased in squarnous neoplasia compared to normal, and CD44v6 and v7/8 expressions were increased, however, there was no statistical significance. Accentuated staining of CD44v6 and v7/8 along the infiltrating borders was noted in 76.9% and 69.2% of MI and in 71.4% and 42.9% of CA, respectively. High MVD and VEGF 2+ expression were higher in the squamous neoplasia compared to narmal, however, there was no significant difference between the squamous neoplasia and no significant relationship between MVD and VEGF expression. The expression rates of CD44std and CD44v6 were higher in HPV 16/18 negative squamous neoplasia and that of CD44v7/8 was higher in HPV 16/18 pasitive squamous neoplasia, however, their differences were not significant. The incidences of high MVD and VEGF 2+ expression were higher in HPV 16/18 positive suqmaous neoplasia with no statistical significance. CONCLUSIONS: These results suggest that CD44 variants expression and angiogenesis are involved in the development of squamous neoplasia of the uterine cervix, however, HPV 16/18 might not be related to CD44 variant expression and angiogenesis.
Carcinoma, Squamous Cell ; Cervix Uteri* ; Female ; Incidence ; Microvessels* ; Polymerase Chain Reaction ; Vascular Endothelial Growth Factor A*

Stomach of 34 year old man showed an early stage of the cancer with slight involvement of the superficial part of the inner muscle layer and accompanied with one metastatic lymph node. The cancer is that of medium differentiated adenocarcinoma. There is an heavy infiltration of lymphocytes mixed with histiocytic mononuclear cells and multinucleated giant cells. Some giant cells appear as Langhans' type suggesting phagocytic cells of their origin containing PAS positive materials in the cytoplasma. In other places, they appear as atrophic cancer nests suggesting that these tumor nests were arrested and undergone to regressive cellular process because of the over-whelming immunological pressure by the host.
Male ; Humans ; Neoplasm Metastasis ; Stomach Neoplasms

Education on the physician continues with undergraduate medical education, graduate medical education, and continuous medical education. The countries such as the United States, Japan, the United Kingdom, German, and others are required to undergo training in the clinical field for 2 years after completing the national medical examination, and to become doctors after passing the clinical practice license test. Korea can obtain a medical license and become a clinical doctor at the same time if it passes written and practical tests after completing 6 years of undergraduate medical education or 4 years of graduate school. About 90% of medical school graduates replace clinical practice with 4–5 years of training to acquire professional qualifications, but this is an option for individual doctors rather than an extension of the licensing system under law. The medical professional qualification system is implemented by the Ministry of Health and Welfare on the regulation. In fact, under the supervision of the government, the Korean Hospital Association, the Korean Medical Association, and the Korean Academy of Medical Sciences progress most procedures. After training and becoming a specialist, the only thing that is given to a specialist is the right to mark him or her as a specialist in marking a medical institution and advertising. The government's guidelines for professional training are too restrictive, such as the recruitment method of residents, annual training courses of residents, dispatch rule of the residents, and the quota of residents of training hospitals. Although professional training systems are operated in the United States, the United Kingdom, France, and Germany, most of them are organized and operated by public professional organizations and widely recognize the autonomy of academic institutions and hospitals. Korea should also introduce a compulsory education system after graduating from medical education and organize and initiate by autonomic public professional organization that meets global standards.

Acral lentiginous nevus(ALN) is a new disease entity recently proposed by Clemente et al in 1995. The main histopathological features of ALN are characterized by elongation of the rete ridges, lentiginous proliferation of melanocytes at the dermo-epidermal junction, the presence of melanocytes within the upper epidermis, poor or absent lateral circumscription of the intraepithelial melanocytes and, in the dermis, fibroplasia, vascular neogenesis, and lymphoid infiltration, which enable clinicians to distinguish these nevi from ordinary nevi and melanoma. We, herein, report a case of ALN of plantar skin with unique histopathological characteristics.
Dermis ; Epidermis ; Melanocytes ; Melanoma ; Nevus* ; Skin

A 62-year-old woman with hereditary hemorrhagic telangiectasia(HHT) or Osler-Weber-Rendu disease involving the liver is presented. Imaging findings including color Doppler sonograph and CT findings are described.
Female ; Humans ; Liver* ; Middle Aged

No abstract available.
Breech Presentation* ; Female ; Fetus* ; Pregnancy

PURPOSE: Leptomeningeal cyst or growing skull fracture can occur in young infants or children following head trauma. We present MR imaging findings in five children with growing skull fracture. MATERIALS AND METHODS: We reviewed the MR images of five children (M: F=2:3) with growing skull fracture. The mean age was 7.5 years. The time interval between the occurrence of head trauma and the presentation of growing skull fracture varied from three months to 12 years. We reviewed the precontrast CT scans and/or the plain skull radiographs in those patients for whom these studies were available. RESULTS: The most common location of the growing skull fracture was the parietal bone (n=3). On the MR images, there were bone defects with posttraumatic cystic encephalomalacia or porencephalic cysts. Marginal bony thickening and diploic space widening were noted in four patients. MR imaging was excellent for visualizing the parenchymal changes and pericranial lesions. CONCLUSION: In children with growing skull fracture, MR imaging can clearly depict trauma-related parenchymal changes, pericerebral lesions as well as bony edge thickening with remodeling.
Arachnoid Cysts ; Child* ; Craniocerebral Trauma ; Encephalomalacia ; Humans ; Infant ; Magnetic Resonance Imaging ; Parietal Bone ; Skull Fractures* ; Skull* ; Tomography, X-Ray Computed