1.Comparison of Oxygenation and Lung Damage of High Frequency Flow Interruption to Conventional Ventilation in Surfactant Deficient Rabbits.
Chang Keun KIM ; Churl Young CHUNG ; Hye Jae CHO
Journal of the Korean Pediatric Society 1995;38(5):591-601
No abstract available.
Lung*
;
Oxygen*
;
Rabbits*
;
Ventilation*
2.IgE in atopic dermatitis.
Hye Won CHEON ; Chung Koo CHO ; Sung Nack LEE
Korean Journal of Dermatology 1981;19(6):847-851
Serum IgE values were determined in 100 patients vith atogic dermatitis in the Department of Dermatology at Severance Hospital, Yonsei University College of Medicine, from Oct. 1, 1978 to Mar. 31, 1980. Mean IgE value of patients is 293. 4 unit/ml which is significantly higher than reference value, and the following results were obtained. 1. The mean IgE value in adults with atopic dermatitis, 339.8 unit/ml, 30 cases: more tian 16 years old) was significantly higher than in children(251. 4 unit /ml, 70 cases). 2. Male patierts showed higher IgE va,lue (mean 324. 5 unit/ml, 62 cases,' than female patients (242.7 unit/ml, 38 cases). 3. No close correlation was demonstrated between IgE values and eosiniphils in blood. 4. Patients with parasitic infesta,tion (5 cases) showed relatively increased IgE values (mean; 116. 2 unit/ml;. 5. Patients wifh bronchial asthma (2 cases) showed high IgE values exceeding 1000 unit/ml, 6. IgE. values roughly correlated with severity of the dermatitis. Four cases with high IgE values exceeding 1000 unit/ml were included in the clinically severe group.
Adult
;
Asthma
;
Dermatitis
;
Dermatitis, Atopic*
;
Dermatology
;
Female
;
Humans
;
Immunoglobulin E*
;
Male
;
Reference Values
4.Effect of Additional Epinephrine on Spinal Anesthesia with Bupivacaine.
Moon Seong CHO ; Hye Ryung CHUNG ; Tae Hwan KIM
Korean Journal of Anesthesiology 1998;35(5):926-932
Background: Bupivacaine was introduced to be a long-acting spinal anesthetic agent. It has been argued about whether the addition of epinephrine prolongs the bupivacaine action or not. The aim of this present investigation was to find out the effect of additional epinephrine on spinal anesthesia with bupivacaine. Methods: 47 patients undergoing an operation on lower extremity were randomly allocated to 2 groups. All patients were anesthetized by subarachnoid block with 0.5% bupivacaine in 8% glucose, which was mixed with 0.2 ml of normal saline in group non-E (n=24) and 0.2 ml of 1:1,000 epinephrine in group E (n=23). We evaluated blood pressure and heart rate, the sensory and motor blockade and voiding time after spinal anesthesia. Results: The systolic blood pressure (SBP) at 8 and 10 min after anesthesia were lower in group non-E than in group E (p<0.05). The trend of decreasing diastolic blood pressure was similar in both groups. The heart rate(HR) at 2 min after anesthesia was lower in group non-E than in group E (p<0.05). The sensory block in T10 was produced faster in group non-E (7 min) than in group E (11 min)(p<0.05). And the maximal sensory block level and its reaching time was T7 and 14 min in group non-E, and T8 and 17 min in group E (p=0.12, p=0.11). Two segment regression time was 124 min in group non-E, and 184 min in group E (p=011). The onset time of motor block to Bromage scale 3 was 12 min in group non-E and 16 min in group E (p=0.06). The recovery time from complete motor block to Bromage scale 1 after maximal motor block was 263 min in group non-E, and 278 min in group E. The time at which patients voided after anesthesia was 469 min in group non-E, and 466 min in group E. Three patients urinated by using a urinary catheter in each group. Conclusions: The addition of epinephrine to bupivacaine for spinal anesthesia can slow the decrease in SBP and increase the HR at early stage of anesthesia, and slow the sensory block.
Anesthesia
;
Anesthesia, Spinal*
;
Blood Pressure
;
Bupivacaine*
;
Epinephrine*
;
Glucose
;
Heart
;
Heart Rate
;
Humans
;
Lower Extremity
;
Urinary Catheters
5.Diagnostic value of bladder tumors by excretory urography
Cho Hye LEE ; Sin Ho KOOK ; Eun Chul CHUNG ; Chung Sik RHEE
Journal of the Korean Radiological Society 1986;22(5):885-890
Bladder tumors initially may be diagnosed by excretory urography. In this study, 60 excretory urogramsincluding 40 cases of biopsy proved blaadder tumor and 20 cases of cystoscopically normal bladder were analyzed.Five experienced readers reviewed five radiographs of each case. The results were as follows: 1. Male to remaleratio was 5.7:1, and the highest incidence of age distribution was between 60 and 69 year with 48%. 2. The tumorswere chiefly located in lateral wall of bladder. (67%) 3. Among 40 cases, pathologic diagnosis was as follows:Transitional cell ca. 39 cases, and squamous cell ca. lcase. 4. The I.V.P. finding showed 82% of normal upperurinary tract, 13% of hydronephrosis, 5% of non-visualization, and 58% of filling defect in bladder. 5. Originalinterpretation of urogram was as follows: Of 40 cases with bladder ca., 45% as positive, 13% as suspicious, and38% as negative. Of 20 cases with normal, 95% as negative, and 5% as positive. 6. Analysis by this study was asfollows: Accuracy 68%, sensitivity 62%, specificity 80%, false positive rate 38%, and false negative rate 20%. 7.25 min A-P radiograph was most valuable projection and oblique projection did not significantly increasesensitivity.
Age Distribution
;
Biopsy
;
Diagnosis
;
Epithelial Cells
;
Humans
;
Hydronephrosis
;
Incidence
;
Male
;
Sensitivity and Specificity
;
Urinary Bladder Neoplasms
;
Urinary Bladder
;
Urography
6.Association of the CYP1B1 Gene Polymorphism with the Risk of Advanced Endometriosis in Korean Women.
Yeon Jean CHO ; Sung Eun HUR ; Ji Young LEE ; In Ok SONG ; Mi Kyoung KOONG ; Hye Sung MOON ; Hye Won CHUNG
Korean Journal of Fertility and Sterility 2006;33(2):85-95
OBJECTIVE: To investigate whether polymorphisms of gene encoding CYP1B1 is associated with the risk of endometriosis in Korean women. METHODS: We investigated 199 patients with histopathologically confirmed endometriosis rAFS stage III/IV and 183 control group women who were surgically proven to have no endometriosis. The genetic distribution of four different CYP1B1 polymorphisms at G119-T, G432-C, T449-C, and A453-G were analyzed by polymerase chain reaction (PCR) and restriction fragment length polymorphism of PCR products. RESULTS: We found no overall association between each individual CYP1B1 genotype and the risk of endometriosis. The odds ratio of genotype GG/GC+GG/TC+TT/AA compared to GG/CC/CC/AA (reference) was calculated as 2.06 with a 95% confidence interval of 1.003~4.216. CONCLUSIONS: This results suggest that CYP1B1 genetic polymorphism may be associated with development of endometriosis in Korean women.
Endometriosis*
;
Female
;
Genotype
;
Humans
;
Odds Ratio
;
Polymerase Chain Reaction
;
Polymorphism, Genetic
;
Polymorphism, Restriction Fragment Length
7.Second trimester selective termination in a dizygotic twin pregnancy with discordancy for Down's syndrome: A case report.
Hye Sun JUN ; Suk Kyung KIM ; Joo Yun CHO ; Sook Hwan LEE ; Hye Kyung LEE ; Chung Woong KAY
Korean Journal of Obstetrics and Gynecology 2000;43(2):302-304
A 33-year-old-woman with twin pregnancy underwent genetic amniocentesis in our hospital at 16 weeks of gestation. Fetal chromosomal analysis showed 46,XY,inv(9) and 47,XX,+21. The affected twin was terminated by ultrasonographically guided intracardiac injection of 3 ml potassium chloride solution at 19 weeks of gestation. A healthy 2570 g male infant was born by cesarean section with Apgar scores of 8 and 9 at one and five minutes, respectively.
Amniocentesis
;
Cesarean Section
;
Down Syndrome*
;
Female
;
Humans
;
Infant
;
Male
;
Potassium Chloride
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnancy*
;
Pregnancy, Twin
;
Twins, Dizygotic*
8.Relationship between Fatigue, Sleep Disturbance, and Gestational Stress among Pregnant Women in the Late Stages.
Mi Young CHUNG ; Kyung Hye HWANG ; Ok Hee CHO
Korean Journal of Women Health Nursing 2014;20(3):195-203
PURPOSE: The objective of this study was to investigate the relationship between fatigue, sleep disturbance, and gestational stress in women during late stage of pregnancy. METHODS: This study was conducted with 113 healthy pregnant women at gestational age greater than 27 weeks who were registered at community health centers and received prenatal care. A structured questionnaire regarding fatigue, sleep disturbance, and gestational stress was used. The data was analyzed using a t-test, an ANOVA, and Pearson correlation coefficients. RESULTS: The subjects with unplanned pregnancies and irregular exercise patterns showed a higher level of fatigue than those with planned pregnancies and regular exercise patterns. Pregnant women with caffeine intake manifested higher levels of gestational stress and sleep disturbance than those without. The levels of sleep disturbance and gestational stress increased as the fatigue levels increased. The fatigue levels increased with increased levels of sleep disturbance. CONCLUSION: Planned pregnancy, regular exercise patterns, and caffeine intake were related with fatigue, sleep disturbance, and gestational stress in women during late stages of pregnancy. Fatigue, sleep disturbance, and gestational stress had close associations to each other. In the future, such results should guide development of nursing intervention programs for women in late stages of pregnancy.
Caffeine
;
Community Health Centers
;
Family Planning Services
;
Fatigue*
;
Female
;
Gestational Age
;
Humans
;
Nursing
;
Pregnancy
;
Pregnancy, Unplanned
;
Pregnant Women*
;
Prenatal Care
;
Surveys and Questionnaires
;
Sleep Wake Disorders
9.Morphometric Study on the Sigmoid Sinus of the Korean Adults.
Hye Yeon LEE ; In Hyuk CHUNG ; Tai Sun SHIN ; Ho Suck KANG ; Byung Pil CHO
Korean Journal of Physical Anthropology 1989;2(1):25-31
The variations of the sigmoid sinus were studied in 50 Korean adults (average age 67). The classification of the shape and a measurement of the diameters of the sinus were done and the morpological. 1. The shape was classified into 4 types, and the round type was the most common in both sides. S shaped type was below 10% in both sides. 2. The breadth was regular in 54% of the right and in 70% of the left sinuses. According to the breadth change, the shape was classified into 4 shapes. 3. The average diameter was 8.6mm on the right side and 7.2mm on the left side. 4. Symmetry was present in 16% of all. 5. The right transverse sinus was absent in 1 case (2%) and the superior petrosal sinus did not open into the sigmoid sinus in 2 cases (4%). 6. Petrosqamous sinus was observed in 16%.
Adult*
;
Classification
;
Colon, Sigmoid*
;
Humans
10.Six Cases of Congenital Absence of the Vagina Managed by McIndoe Operation.
Sung Duk CHO ; Hye Sun JUN ; Chung No LEE ; In Hyun KIM ; Jae Young AHN
Korean Journal of Obstetrics and Gynecology 1997;40(1):223-228
Mullerian agenesis or dysgenesis, rare developmental anomaly presenting as primary amenorrhea, is characterized by absence of vagina and absence or rudimentary development of the uterus. Anatomic anomalies of the axial skeleton and kindney often accompany this psychologically devatating condition. There are various methods of surgical treatment for congenital absence of the vagina. The six cases reviewed in this paper were all treated with McIndoe technique. All of 6 women experienced satisfactory sexual activity and were satisfied with vaginal depth following vaginal creation using a split thickness skin graft technique. Despite the existence of several alternative methods, the McIndoe technique is a relatively simple and highly successful procedure and hence is still prefered by many surgeons.
Amenorrhea
;
Female
;
Humans
;
Sexual Behavior
;
Skeleton
;
Skin
;
Transplants
;
Uterus
;
Vagina*