1.A Rare Cause of Ureteropelvic Junction Obstruction.
Korean Journal of Urology 2014;55(10):687-689
2.Role of Urinary Levels of Endothelin-1, Monocyte Chemotactic Peptide-1, and N-Acetyl Glucosaminidase in Predicting the Severity of Obstruction in Hydronephrotic Neonates.
Hamid MOHAMMADJAFARI ; Alireza RAFIEI ; Seyed Abdollah MOUSAVI ; Abdulrasool ALAEE ; Yalda YEGANEH
Korean Journal of Urology 2014;55(10):670-676
PURPOSE: Antenatal hydronephrosis (AH) is found in 0.5%-1% of neonates. The aim of the study was to assess the urinary concentrations of 3 biomarkers, endothelin-1 (ET-1), monocyte chemotactic peptide-1 (MCP-1), and N-acetyl-glucosaminidase (NAG) in severely hydronephrotic neonates. MATERIALS AND METHODS: Neonates with a history of prenatal hydronephrosis were enrolled in the prospective study in 2 groups. Group 1 included neonates with severe forms of obstruction requiring surgical intervention and group 2 included neonates with milder forms of obstruction without any functional impairment. Fresh voided urinary levels of ET-1, MCP-1, and NAG were measured and their ratios to urinary Cr were calculated. RESULTS: Fourty-two neonates were enrolled into the 2 groups: group 1, 24 patients (21 male, 3 female); group 2, 18 neonates (16 male, 2 female). There were no statistically significant differences between urinary ET-1, NAG, MCP-1 values, and ET-1/Cr and NAG/Cr ratios in groups 1 and 2. The urinary MCP-1/Cr ratio was significantly higher in group 1 than in group 2. For comparison of groups 1 and 2, the cut-off values were measured as 0.5709 ng/mg (sensitivity, 75%; specificity, 67%; positive predictive value [PPV], 71%; negative predictive value [NPV], 71%), 0.927 ng/mg (sensitivity, 77%; specificity, 72%; PPV, 77%; NPV, 72%), and 1.1913 IU/mg (sensitivity, 62%; specificity, 67%; PPV, 68%; NPV, 60%) for ET-1/Cr, MCP-1/Cr, and NAG/Cr ratios, respectively. CONCLUSIONS: The urinary MCP-1/Cr ratio is significantly elevated in neonates with severe obstruction requiring surgical intervention. Based upon these results, urinary MCP-1/Cr may be useful in identification of severe obstructive hydronephrosis in neonates.
Acetylglucosaminidase/*urine
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Biological Markers/urine
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Chemokine CCL2/*urine
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Endothelin-1/*urine
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Female
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Humans
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Hydronephrosis/*congenital/etiology/surgery/ultrasonography
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Infant, Newborn
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Male
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Predictive Value of Tests
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Prospective Studies
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Sensitivity and Specificity
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Ureteral Obstruction/complications/*diagnosis/surgery
3.Hydronephrosis by an Aberrant Renal Artery: A Case Report.
Byoung Seok PARK ; Taek Kyun JEONG ; Seong Kwon MA ; Soo Wan KIM ; Nam Ho KIM ; Ki Chul CHOI ; Yong Yeon JEONG
The Korean Journal of Internal Medicine 2003;18(1):57-60
Ureteropelvic junction obstruction is usually intrinsic and is most common in children. Aberrant renal arteries are present in about 30% of individuals. Aberrant renal arteries to the inferior pole cross anteriorly to the ureter and may cause hydronephrosis. To the best of our knowledge, although there are some papers about aberrant renal arteries producing ureteropelvic junction obstruction, there is no report of a case which is diagnosed by the new modalities, such as computed tomography angiogram (CTA) or magnetic resonance angiogram (MRA). We describe a 36-year-old woman with right hydronephrosis. Kidney ultrasonogram and excretory urogram revealed right hydronephrosis. CTA and MRA clearly displayed an aberrant renal artery and hydronephrosis. The patient underwent surgical exploration. For the evaluation of hydronephrosis by an aberrant renal artery, use of CTA and MRA is advocated.
Adult
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Female
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Flank Pain/diagnosis/etiology
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Follow-Up Studies
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Humans
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Hydronephrosis/*diagnosis/etiology/surgery
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Magnetic Resonance Angiography/methods
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Renal Artery/*abnormalities/radiography
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Risk Assessment
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Tomography, X-Ray Computed
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Treatment Outcome
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Ureteral Obstruction/*complications/radiography/surgery
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Urography/methods
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Urologic Surgical Procedures/methods
4.Foreign Body Granulomas Simulating Recurrent Tumors in Patients Following Colorectal Surgery for Carcinoma: a Report of Two Cases.
Sang Won KIM ; Hyeong Cheol SHIN ; Il Young KIM ; Moo Joon BAEK ; Hyun Deuk CHO
Korean Journal of Radiology 2009;10(3):313-318
We report here two cases of foreign body granulomas that arose from the pelvic wall and liver, respectively, and simulated recurrent colorectal carcinomas in patients with a history of surgery. On contrast-enhanced CT and MR images, a pelvic wall mass appeared as a well-enhancing mass that had invaded the distal ureter, resulting in the development of hydronephrosis. In addition, a liver mass had a hypointense rim that corresponded to the fibrous wall on a T2-weighted MR image, and showed persistent peripheral enhancement that corresponded to the granulation tissues and fibrous wall on dynamic MR images. These lesions also displayed very intense homogeneous FDG uptake on PET/CT.
Adult
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Aged
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Colorectal Neoplasms/pathology/*surgery
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Contrast Media/diagnostic use
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Diagnosis, Differential
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Fluorodeoxyglucose F18/diagnostic use
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Granuloma, Foreign-Body/complications/*diagnosis
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Humans
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Hydronephrosis/etiology
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Image Enhancement/methods
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Liver/pathology/radionuclide imaging
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Liver Neoplasms/*diagnosis/secondary
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Magnetic Resonance Imaging
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Male
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Pelvic Neoplasms/*diagnosis/secondary
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Pelvis/pathology/radiography
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Positron-Emission Tomography
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Radiopharmaceuticals/diagnostic use
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Tomography, X-Ray Computed