1.Response: Investigating Susceptibility to Diabetes Using Features of the Adipose Tissue in Response to In Utero Polycyclic Aromatic Hydrocarbons Exposure (Diabetes Metab J 2016;40:494-508).
Worlanyo E GATO ; Daniel A HUNTER ; Shamaya L WHITBY ; Christopher A MAYS ; Wilson YAU
Diabetes & Metabolism Journal 2016;40(6):511-512
No abstract available.
Adipose Tissue*
;
Polycyclic Hydrocarbons, Aromatic*
2.Letter: Investigating Susceptibility to Diabetes Using Features of the Adipose Tissue in Response to In Utero Polycyclic Aromatic Hydrocarbons Exposure (Diabetes Metab J 2016;40:494-508).
Diabetes & Metabolism Journal 2016;40(6):509-510
No abstract available.
Adipose Tissue*
;
Polycyclic Hydrocarbons, Aromatic*
3.Relationship between PAHs Concentrations in Ambient Air and Deposited on Pine Needles.
Environmental Health and Toxicology 2011;26(1):e2011004-
OBJECTIVES: This study was carried out to determine whether or not pine needles can be used as passive samplers of atmospheric polycyclic aromatic hydrocarbons (PAHs) using the correlation between accumulated PAH concentrations in air (Ca, ng/m3) and those deposited on pine needles (Cp, ng/g dry). METHODS: PAHs in ambient air was collected using low volume PUF sampler and pine needles was gathered at same place for 7 months. RESULTS: good correlation (R2=0.8582, p<0.05) was found between Ca and Cp for PAHs with a higher gaseous state in air (AcPy, Acp, Flu, Phen, Ant, Flt, Pyr, BaA and Chry), but there was a poorer correlation (R2=0.1491, p=0.5123) for the PAHs with a lower gaseous state (BbF, BkF, BaP, DahA, BghiP and Ind123). A positive correlation (R2=0.8542) was revealed between the logarithm of the octanol-air partitioning coefficient (logKoa) and Cp/Ca for the PAHs with a higher gaseous state in air, but there was a negative correlation (R2=0.8131) for the PAHs with a lower gaseous state. The Ca-Cp model could not be used to estimate PAHs concentrations in air using deposited PAHs concentrations on pine needles, but the logKoa-Cp/Ca model could be used. CONCLUSIONS: It was found that pine needles can be used as passive samplers of atmospheric PAHs.
Ants
;
Hypogonadism
;
Mitochondrial Diseases
;
Needles
;
Ophthalmoplegia
;
Polycyclic Hydrocarbons, Aromatic
4.Atmospheric concentration and mutagenicity of organic pollutants of suspended particulate in Seoul.
Dong Chun SHIN ; Yong CHUNG ; Young Hahn MOON ; Jae Hoon ROH
Korean Journal of Preventive Medicine 1990;23(1):43-56
To evaluate the difference of concentration and mutagenicity of organic pollutants between residential and traffic area of Seoul, air samples were collected in Bulkwang (residential) and Shinchon (traffic) area. Samples were analyzed to measure the concentration of extractable organic matters (EOM) and their subfractions and mutagenicites were tested using Salmonella typhimurium TA 98. The concentrations of polycyclic aromatic hydrocarbons (PAHs) were also measured by gas-chromatography and compared between two areas. The results were as follows ; 1. While the concentration of total suspended particulate (TSP) in residental area was below the environmental standard in annual average, the concentration in traffic area was above the standard and was up to its maximum 256 microgram/m3 in November. The difference of TSP concentrations in both areas of each month was statistically significant (P<0.05). 2. The concentration of fine particle in traffic area was significantly higher compare to that in residential area and showed statistically significant monthly difference in both areas (P<0.05). The proportion of concentration of fine particle to TSP was 55-68%. 3. Mean concentrations of EOM in residential and traffic areas were 4.3 microgram/m3 and 5.3 microgram/m3 respectively. The proportion of amount of EOM from fine particle to EOM from TSP was 70-88%. 4. While the percentage of polar neutral organic compounds (POCN) of fine particle in Bulkwang's sample was higher compare to Shinchon's sample, the percentage of aliphatic compounds of fine particle in Shinchon's sample was higher compare to Bulkwang's sample. The percentages of PAH fraction were as low as 6-10% in both areas. 5. The mutagenic activity of unit concentration of organic matters extracted from fine particle was higher compare to that of coarse particle and was increased when metabolically activated with S9. Mutagenicities with metabolic activation calculated by unit air volume were significantly different between residential and traffic area, 17 revertants/m3 and 22 revertants/m3 respectively. 6. The concentrations of benzo(a)pyrene in fine particle of traffic and residential areas were 3.10 microgram/m3 and 2.02 microgram/m3 respectively. Sixteen PAHs were higher in samples of traffic area compare to residential area and also concentrations of PAHs in fine particle were higher compare to coarse particle.
Benzo(a)pyrene
;
Biotransformation
;
Polycyclic Hydrocarbons, Aromatic
;
Salmonella typhimurium
;
Seoul*
5.Role of Arbuscular Mycorrhizal Fungi in Phytoremediation of Soil Rhizosphere Spiked with Poly Aromatic Hydrocarbons.
Mycobiology 2005;33(1):41-50
Results from an innovative approach to improve remediation in the rhizosphere by encouraging healthy plant growth and thus enhancing microbial activity are reported. The effect of arbuscular mycorrhizal fungi (Am) on remediation efficacy of wheat, mungbean and eggplant grown in soil spiked with polyaromatic hydrocarbons (PAH) was assessed in a pot experiment. The results of this study showed that Am inoculation enhanced dissipation amount of PAHs in planted soil, plant uptake PAHs, dissipation amount of PAHs in planted versus unplanted spiked soil and loss of PAHs by the plant-promoted biodegradation. A number of parameters were monitored including plant shoot and root dry weight, plant tissue water content, plant chlorophyll, root lipid content, oxido-reductase enzyme activities in plant and soil rhizosphere and total microbial count in the rhizospheric soil. The observed physiological data indicate that plant growth and tolerance increased with Am, but reduced by PAH. This was reflected by levels of mycorrhizal root colonization which were higher for mungbean, moderate for wheat and low for eggplant. Levels of Am colonization increased on mungbean > wheat > eggplant. This is consistent with the efficacy of plant in dissipation of PAHs in spiked soil. Highly significant positive correlations were shown between of arbuscular formation in root segments (A)) and plant water content, root lipids, peroxidase, catalase polyphenol oxidase and total microbial count in soil rhizosphere as well as PAH dissipation in spiked soil. As consequence of the treatment with Am, the plants provide a greater sink for the contaminants since they are better able to survive and grow.
Biodegradation, Environmental*
;
Catalase
;
Catechol Oxidase
;
Chlorophyll
;
Colon
;
Fungi*
;
Hydrocarbons
;
Hydrocarbons, Aromatic*
;
Peroxidase
;
Plant Shoots
;
Plants
;
Rhizosphere*
;
Soil*
;
Solanum melongena
;
Triticum
6.Monitoring of Polycyclic Aromatic Hydrocarbons and the metabolites in Workers using Coal tar Paints.
Eun A KIM ; Jong Tae LEE ; Eun Hye KWON ; Jong Seong LEE ; Yong Hack LEE ; Hyun Seok KWAG ; Seong Bong CHOI ; Iu Jin LEE ; Jae Hoon SHIN ; Kwang Jin SHIM ; Sang Hwa URM ; Sung Jun KIM ; Hae Sook SHON ; Jin Ho CHUN
Korean Journal of Occupational and Environmental Medicine 2005;17(3):161-172
OBJECTIVE: In this study, the exposure levels of polycyclic aromatic hydrocarbons (PAHs) and urinary 1-hydroxypyrene(1-OHP) were surveyed among the workers using coal tar paint. METHOD: The study subjects for the exposed group were 107 male coal tar workers in 10 factories, and for the comparison group were 201 male clerk workers who had never been exposed to coal tar paint. Ambient PAHs, and pre-shift and end-shift urinary 1-OHP were sample and 16 PAHs were analysed. Smoking history was recorded during the survey day. RESULTS: The geometric mean of ambient concentration of total PAHs was 120.17 microgram/m3. Naphthalene had the highest level among the 16 PAHs. The pre-shift 1-OHP in the exposed group (8.89 micro mol/mol creatinine) was significantly higher than that in the control group (0.29 micro mol/mol creatinine). The end-shift 1-OHP in the exposed group (19.02 micro mol/mol creatinine) was significantly higher than that in the pre-shift (8.89 micro mol/mol creatinine) (Ed- confirm). 1-OHP of smokers was significantly higher than that of non-smokers in both groups. The difference between pre-shift and end-shift 1-OHP in smokers (12.40 micro mol/mol creatinine) was twice as high as that in non-smokers (6.06 micro mol/mol creatinine). The difference of 1-OHP between smokers and nonsmokers was 7.59 micro mol/mol creatinine in pre-shift and 13.96 micro mol/mol creatinine in end-shift. Thus, the effect of smoking and exposure to PAHs on 1-OHP may not be additive. In regression analysis for 1-OHP, the significant independent variables were pre-shift 1-OHP and PAHs. The direction of these variables was positive. When the analysis was performed in workers exposed to higher PAHs, smoking was significant independent variable. CONCLUSION: The above results suggest that not only ambient PAHs but also smoking, one of the most important non-occupational PAHs source, influenced the level of 1-OHP. Moreover, the effect of smoking to 1-OHP changed according to the exposure level of PAHs.
Coal Tar*
;
Coal*
;
Creatinine
;
Humans
;
Male
;
Paint*
;
Polycyclic Hydrocarbons, Aromatic*
;
Smoke
;
Smoking
7.Effect of STEL-toluene on Metabolism of Benzene in Rats.
Jaehoon ROH ; Dong Chun SHIN ; Jung Gyun PARK ; Young Hahn MOON ; Ho Keun CHUNG
Korean Journal of Preventive Medicine 1988;21(1):152-162
Benzene and toluene, which are widely used aromatic hydrocarbons in workplace, are recently proved to cause health hazards due to their toxic effects. This study investigated the influence of toluene on the urinary excretion of benzene metabolite by administering short term exposure limit(STEL) of these compounds(i.e., 13.8mg/kg of benzene and 108.8mg/kg of toluene) intraperitoneally into Sprague-Dawley rats. After administration, urinary phenol concentration of rat was measured by gas chromatography for every three hours. Data were analyzed by non-parametric statistical methods using Kruskal-Wallis multi-sample test and Mann-Whitney U test. The following results were obtained: 1. Administration of STFL-benzene increased urinary phenol concentration in rats. 2. Urinary phenol concentration was increased logarithmically according to the dosage of benzene. 3. Excretion of phenol in urine was decreased when benzene and toluene were administered simultaneously compared with administering benzene alone. In Summary, these results reveal that administration of STEL of toluene has antagonistic effect of urinary excretion of benzene metabolite in rats.
Animals
;
Benzene*
;
Chromatography, Gas
;
Hydrocarbons, Aromatic
;
Metabolism*
;
Phenol
;
Rats*
;
Rats, Sprague-Dawley
;
Threshold Limit Values
;
Toluene
8.An Unexpected Death Related to Accidental Gasoline Inhalation.
So Woon KIM ; Young Man LEE ; Kyounghong LEE ; Jong Shin PARK ; Jaehong PARK ; Byung Ha CHOI ; Sohyung PARK
Korean Journal of Legal Medicine 2016;40(3):83-87
Gasoline is a chemical compound of aliphatic and aromatic hydrocarbons, and it easily vaporizes because of its volatile characteristics. Gasoline inhalation may occur accidentally or intentionally in various situations which could result in acute non-lethal or lethal intoxication. Given that gasoline is widely used in everyday life, it is surprising that deaths related to gasoline inhalation rarely occur. We presented a rare case of unexpected death related to gasoline inhalation with the postmortem findings and features.
Autopsy
;
Death, Sudden
;
Forensic Toxicology
;
Gasoline*
;
Hydrocarbons, Aromatic
;
Inhalation*
;
Intention
;
Poisoning
9.Structure, catalytic mechanism and applications of laccases: a review.
Honghua GE ; Yun WU ; Yazhong XIAO
Chinese Journal of Biotechnology 2011;27(2):156-163
Laccases (benzenediol: oxygen oxidoreductases; EC 1.10.3.2) are copper-containing polyphenol oxidases that can oxidize a wide range of aromatic compounds, concomitantly with the transfer of four electrons and the reduction of molecular oxygen to water. The progress on the research of laccases structure and function is reviewed. Their three-dimensional structures and catalytic mechanism, as well as their applications in different fields are emphasized.
Catalysis
;
Hydrocarbons, Aromatic
;
isolation & purification
;
metabolism
;
Laccase
;
chemistry
;
metabolism
;
Oxidation-Reduction
10.Research on exposure to polycyclic aromatic hydrocarbons during pregnancy and risk of preterm birth.
Xiaolan CHEN ; Zhiwen LI ; Email: LIZW@BJMU.EDU.CN.
Chinese Journal of Preventive Medicine 2015;49(7):665-668
Polycyclic aromatic hydrocarbons (PAH) are a group of toxic pollutants existing in the environment widely, and can be taken into the body through various ways containing the digestive tract, respiratory tract and so on. Pregnant women and newborn infants are important and susceptive populations. Relevant study evidences indicate that exposure to PAH during pregnancy may be a important risk factor of preterm delivery, but the special mechanism isn't very clear and may be related with DNA damage, oxidative stress, systemic inflammation, endocrine disruption and so on. This paper reviewed related contents including the influences and evaluation methods of exposure to PAH during pregnancy, increasing risk and potential mechanism for preterm delivery of exposure to PAH during pregnancy.
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Maternal Exposure
;
Polycyclic Aromatic Hydrocarbons
;
Pregnancy
;
Premature Birth