1.Statistical Analysis of Prognostic Factors in Hyaline Membrane Disease.
Journal of the Korean Pediatric Society 1984;27(1):19-24
No abstract available.
Humans
;
Hyalin*
;
Hyaline Membrane Disease*
;
Infant, Newborn
2.Clinicao-Pathologic Study on Hyaline Membrane Disease.
Journal of the Korean Pediatric Society 1983;26(6):534-544
No abstract available.
Humans
;
Hyalin*
;
Hyaline Membrane Disease*
;
Infant, Newborn
3.Clinical Studies on the Hyaline Membrane Disease.
Jung Hee LEE ; Gyoung Hee KIM ; Keun LEE
Journal of the Korean Pediatric Society 1984;27(9):859-864
No abstract available.
Humans
;
Hyalin*
;
Hyaline Membrane Disease*
;
Infant, Newborn
4.Exogenous Surfactant Replacement Therapy of Hyaline Membrane Disease: A controlled clinical trial.
Ran NAMGUNG ; Chul LEE ; Kook In PARK ; Dong Gwan HAN
Journal of the Korean Pediatric Society 1990;33(1):22-35
No abstract available.
Humans
;
Hyalin*
;
Hyaline Membrane Disease*
;
Infant, Newborn
5.Factors Associated with Pneumothorax in Hyaline Membrane Disease In fants Receiving Mechanical Ventilation.
Oh Kyung LEE ; Kyung Hee KIM ; Kyu Sun CHOI ; Wan Seoub KIM
Journal of the Korean Pediatric Society 1989;32(12):1642-1649
No abstract available.
Humans
;
Hyalin*
;
Hyaline Membrane Disease*
;
Infant, Newborn
;
Pneumothorax*
;
Respiration, Artificial*
6.The significance of nucleated red blood cell counts in various conditions associated with acute or chronic perinatal asphyxia.
Suck Kyu HUR ; Moon Sang PARK ; Mee Kyung NAMGOONG ; Hwang Min KIM ; Jae Seung YANG ; Baek Keun LIM ; Jong Soo KIM ; Myung Seo KANG
Journal of the Korean Pediatric Society 1992;35(11):1514-1519
No abstract available.
Asphyxia*
;
Erythrocyte Count*
;
Erythrocytes*
;
Humans
;
Hyaline Membrane Disease
;
Infant, Newborn
7.A Case of Dexamethasone induced Hypertrophic Cardiomyopathy in Neonate with Bronchopulmonary Dysplasia.
Youn Jung CHOI ; Soon Mi JUNG ; Jae Kyun YOON ; Ki Hyeng LEE ; Chang Sung SON ; Young Chang TOCKO
Journal of the Korean Pediatric Society 1998;41(5):711-715
Although hypertrophic cardiomyopathy is uncommon in infant and children, we have experienced a case of dexamethasone induced hypertrophic cardiomyopathy in preterm baby who had bronchopulmonary dysplasia. This patient had hyaline membrane disease. Therefore, he received prolonged mechanical ventilation that resulted in bronchopulmonary dysplasia. After we carried out dexamethasone therapy for 7 days, hypertrophic cardiomyopathy appeared in his echocardiographic finding. We discontinued dexamethasone and then, hypertrophic cardiomyopathy improved. We report this case with the review of the associated literatures.
Bronchopulmonary Dysplasia*
;
Cardiomyopathy, Hypertrophic*
;
Child
;
Dexamethasone*
;
Echocardiography
;
Humans
;
Hyaline Membrane Disease
;
Infant
;
Infant, Newborn*
;
Respiration, Artificial
8.New Synthetic Surfactants for Neonates.
Journal of the Korean Society of Neonatology 2012;19(4):184-194
The benefits of exogenous synthetic or animal-derived natural surfactants for treatment of respiratory distress syndrome (RDS) are well established. Although synthetic surfactants have potential safety advantages over animal-derived products, they seem to be clinically inferior to animal-derived natural surfactant, based on the results of numerous comparative trials. In recent years, however, synthetic surfactant has experienced a surge in breakthroughs to the point of rivaling natural surfactant, mainly due to the development of protein-containing synthetic surfactant. This article will review the historical background on the development of artificial pulmonary surfactant, compositional and physicochemical aspects on pulmonary surfactant lipids and proteins, results of comparative trials among natural, protein-free and protein-containing surfactants, and current status of development of protein-containing surfactants for treatment of RDS.
Humans
;
Hyaline Membrane Disease
;
Infant, Newborn
;
Infant, Premature
;
Proteins
;
Pulmonary Surfactants
;
Surface Tension
;
Surface-Active Agents
9.Relationship between serum estradiol levels in the early postnatal period and the occurrence of hyaline membrane disease and bronchopulmonary dysplasia in neonates.
Li-Juan ZHANG ; Bin WANG ; Guo-Sheng LIU
Chinese Journal of Contemporary Pediatrics 2010;12(11):864-866
OBJECTIVEThis study examined the changes of serum levels of estradiol during the early postnatal period in neonates in order to investigate the possible relationship between the serum estradiol levels and the occurrence of pulmonary hyaline membrane disease (HMD) and bronchopulmonary dysplasia (BPD).
METHODSFifty-nine premature infants with the gestational age between 26 and 32 weeks and 61 full-term infants with the gestational ages between 37 and 42 weeks were enrolled. Serum levels of estradiol were measured on postnatal days 1, 3 and 7.
RESULTSSerum levels of estradiol decreased rapidly after birth in both premature and term infants and there were significant differences among different postnatal ages groups. However, there were no significant differences in the serum estradiol levels between the premature and term groups on postnatal days 1, 3 and 7. Serum estradiol levels measured in premature infants with HMD were not statistically different from those in premature infants without HMD on all time points. Serum estradiol levels in premature infants with BPD were higher than those in premature infants without BPD on postnatal day 3, but there were no noticeable differences on postnatal days 1 and 7.
CONCLUSIONSSerum estradiol levels decline rapidly within 7 days after birth in both premature and term infants. Serum estradiol levels in the early postnatal period are not associated with the occurrence of HMD and BPD, suggesting that serum estradiol in the early postnatal period can not be used as a marker for predicting the development of HMD and BPD.
Biomarkers ; Bronchopulmonary Dysplasia ; blood ; Estradiol ; blood ; Female ; Humans ; Hyaline Membrane Disease ; blood ; Infant, Newborn ; Male
10.The Effect of Corticosteroid Therpy in the Very Premature Infant.
Hye Jeong KIM ; Mi Ja PARK ; Jae Yoon KIM ; Young JIn HONG ; Don Hee AHN
Journal of the Korean Society of Neonatology 1997;4(2):178-186
PURPOSE: Our purpose was to deterrnine the efficacy of maternal corticosteroid therapy on the morbidity of premature infants between 26 and 31 weeks' gestation. METHOD: A total of 62 premature infants between 26 and 31 weeks gestation admitted to pediatric department of National Medical Center from Nov, 1990 to June 1996 were analyzed to evaluate the efficacy of prenatal corticosteroid therapy on the morbidity such as hyaline membrane disease, intreventricular hernorrhage, necrotizing enterocolitis, sepsis, neonatal death, days on ventilation and hospital days. RESULT: Among 62 women who delivered premature infants between 26 and 31 weeks, 22 received betamethasone before delivery and 40 did not. 1) The rate of hyaline membrane disease was less in the betamethasone group (41% vs. 70%, P<0.05). 2) The rate of intracranial hemorrhage was less in the betamethasone group (0 vs. 20%, P<0.05). 3) The days of ventilator care was less in the betamethasone group among survival cases (27+/-3.2 vs. 5.2+/-4.6, P<05). 4) Arnong 14 women who delivered at 26 to 28 weeks, 4 received betamethasone before delivery and 10 did not. The rate of neonatal death was less in the betamethasone group (o% vs. 80%, P<0.05). 5) Among 48 women who delivered at 29 to 31 weeks, 18 received betamethasone before delivery and 30 did not. The rate of hyaline membrane disease was less in the betamethasone group (39% vs. 73%, P<0.05). CONCLUSION: Betamethasone appears to reduce hyaline membrane disease, intraven- tricular hemorrhage, neonatal death and the morbidity significantly in premature infants between 26 and 31 weeks' gestation.
Betamethasone
;
Enterocolitis, Necrotizing
;
Female
;
Hemorrhage
;
Humans
;
Hyaline Membrane Disease
;
Infant, Newborn
;
Infant, Premature*
;
Intracranial Hemorrhages
;
Pregnancy
;
Sepsis
;
Ventilation
;
Ventilators, Mechanical