Purpose: The aim of this study was to identify the double mediating effect of effect of diversity sensitivity orientation and positive nursing organizational culture between diversity management and organizational commitment. Methods: Participants were 245 nurses working in six tertiary hospitals located in 3 different regions. Data collection was conducted from February 13, 2023 to March 6, 2023 through online self-reported questionnaire. The data were analyzed by IBM SPSS Statistics 27 and SPSS PROCESS Macro 4.2 program. Results: The direct effect of diversity management on organizational commitment was significant (β = .21, p < .001). The indirect effect of diversity management on organization commitment was .34 (95% confidence interval [CI] = .23~.47). The double mediating effect of diversity sensitivityorientation and positive nursing organizational culture in the relationship between diversity management and organizational commitment was .02 (95% CI = .00~.05). Conclusion Diversity sensitivity orientation and positive nursing organizational culture show double mediating effect on the relationship between diversity management and organizational commitment. Education program and human resource management strategy for enhancing diversity management, diversity sensitivity orientation and positive nursing organizational culture should be provided to improve organizational commitment, and which are needed active support of the association and nursing organization.

No abstract available.
Neurofibroma, Plexiform* ; Urinary Bladder*

OBJECTIVES: This study was performed to consider the clinical experience of an ultrasound-guided vacuum-assisted resection (Mammotome) for benign breast lesions through a core needle biopsy. METHODS: The authors carried out a core needle biopsy and Mammotome for 347 patients and investigated the pathologic results. RESULTS: The significant difference of core needle biopsy and Mammotome results was demonstrated, Spearman correlation coefficient is 0.413 in a correlation analysis. CONCLUSION: This experience suggest Mammotome is a useful procedure for providing more correct pathologic findings through complete resection of benign breast lesions.
Biopsy, Large-Core Needle ; Breast ; Breast Diseases ; Breast Neoplasms ; Humans ; Mammography ; Needles

Aggressive angiomyxomas (AAMs) are rare, benign, but locally aggressive, hypocellular soft tissue neoplasms found in the vulvovaginal region. AAMs are most commonly found in women in their reproductive years. Only about 150 cases of this rare, soft tissue tumor have been reported thus far, most of which are reported from the gynecologic, obstetric, urologic, and pathologic fields. AAMs are considered to be a slow-growing mesenchymal tumor with a locally infiltrative growth pattern. There are only two reports of metastasic disease. We have managed a case of AAM which occurred during adolescence and was pathologically-confirmed.
Adolescent ; Female ; Humans ; Myxoma ; Soft Tissue Neoplasms ; Vulva

Aggressive angiomyxomas (AAMs) are rare, benign, but locally aggressive, hypocellular soft tissue neoplasms found in the vulvovaginal region. AAMs are most commonly found in women in their reproductive years. Only about 150 cases of this rare, soft tissue tumor have been reported thus far, most of which are reported from the gynecologic, obstetric, urologic, and pathologic fields. AAMs are considered to be a slow-growing mesenchymal tumor with a locally infiltrative growth pattern. There are only two reports of metastasic disease. We have managed a case of AAM which occurred during adolescence and was pathologically-confirmed.
Adolescent ; Female ; Humans ; Myxoma ; Soft Tissue Neoplasms ; Vulva

Lipomatous tumors are the most common mesenchymal tumor. But, pure lipoma of the uterus is very rare and only few cases are reported in international literatures. These tumors usually develop in postmenopausal women and symptoms are similar to leiomyoma. We report a case of a pure uterine lipoma in 64-years-old woman presenting with palpable pelvic mass and voiding difficulty in which a preoperative diagnosis was made by magnetic resonance imaging (MRI), then pathologically confirmed after the operation.
Female ; Humans ; Leiomyoma ; Lipoma ; Magnetic Resonance Imaging ; Uterus

Chorioangioma is the most common benign tumor of the placenta and associated with adverse perinatal outcome. The prevalence of chorioangioma of the placenta is about 1 percent. The most placental chorioangioma has no clinical significance. But the uncommon large (greater than 5 cm in diameter) chorioangioma may produce both maternal and fetal complications, such as polyhydramnios, preterm labor, fetal heart failure, hydrops fetalis, fetal growth restriction, fetal microangiopathic hemolytic anemia, fetal thrombocytopenia, toxemia of pregnancy, maternal thrombocytopenia, and maternal coagulopathy. The ultrasonography and Color Doppler are used for diagnosis of these lesions. If chorioangioma is suspected, Color Doppler study is informative to confirm the presence of the vascular channels. We report a case of multiple chorioangioma combined with oligohydramnios and discuss the noxious effects of this benign tumor on the mother and the fetus.
Anemia, Hemolytic ; Diagnosis ; Female ; Fetal Development ; Fetal Heart ; Fetus ; Hemangioma* ; Humans ; Hydrops Fetalis ; Mothers ; Obstetric Labor, Premature ; Oligohydramnios* ; Placenta ; Polyhydramnios ; Pre-Eclampsia ; Pregnancy ; Prevalence ; Thrombocytopenia ; Ultrasonography

OBJECTIVES: We examined the effect of sildenafil citrate on advanced glycation end products (AGEs)-induced soluble fms-like tyrosine kinase 1 (sFlt-1) release in JEG-3 choriocarcinoma cells. METHODS: Cells were incubated with control bovine serum albumin (BSA) or AGEs-BSA, and expression of sFlt-1 mRNA and protein release was determined by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. AGEs-BSA increased sFlt-1 mRNA expression and protein release in a dose-dependent manner. RESULTS: Sildenafil citrate suppressed sFlt-1 mRNA expression and protein release in cells treated with AGEs-BSA in a dose-dependent manner. Likewise, it inhibited the increase of reactive oxygen species (ROS) production and NF-kappaB activity in these cells. Cobalt protoporphyrin (CoPP) and bilirubin also inhibited sFlt-1 release and ROS production in cells treated with AGEs-BSA, whereas zinc protoporphyrin IX (ZnPP IX) antagonized the effect of sildenafil citrate. In cells transfected with the heme oxygenase-1 (HO-1) siRNA, sildenafil citrate failed to inhibit the sFlt-1 release and ROS production. CONCLUSION: These results strongly suggest that sildenafil citrate inhibits sFlt-1 release and ROS production in cells treated with AGEs-BSA through upregulation of the HO-1 expression in JEG-3 cells.
Bilirubin ; Choriocarcinoma ; Citric Acid ; Cobalt ; Enzyme-Linked Immunosorbent Assay ; Female ; Glycosylation End Products, Advanced ; Heme Oxygenase-1* ; NF-kappa B ; Pregnancy ; Reactive Oxygen Species ; RNA, Messenger ; RNA, Small Interfering ; Serum Albumin, Bovine ; Up-Regulation* ; Vascular Endothelial Growth Factor Receptor-1 ; Zinc ; Sildenafil Citrate

Adenoid basal carcinoma of the uterine cervix is uncommon neoplasia mostly occurring in postmenopausal women. It has excellent prognosis and a favorable clinical course. In addition, adenoid basal carcinoma is differentiated from adenoid cystic carcinoma by histologic and cellular morphologies, and immunohistochemistry. In this paper, we present the case of a 22 year old Korean female. She initially had a high-grade squamous intraepithelial lesion (HSIL) on Pap smear and a subsequent cervical loop electrosurgical excision procedure (LEEP) specimen revealing adenoid basal carcinoma. The lesion showed the histologic characteristics of adenoid basal carcinoma. Because of the lesion's low potential for recurrence and metastasis, the young primipara had a conization procedure performed and has been under close observation.
Adenoids* ; Carcinoma, Adenoid Cystic ; Cervix Uteri* ; Conization ; Female ; Humans ; Immunohistochemistry ; Neoplasm Metastasis ; Prognosis ; Recurrence

Uterine leiomyoma is one of the most common gynecological tumor, whereas acute torsion of the uterine leiomyoma is very rare. We report a case of subserosal leiomyoma that was first detected by ultrasonography, and further confirmed as torsion of subserosal leiomyoma by laparoscopic surgery.
Laparoscopy ; Leiomyoma* ; Torsion Abnormality ; Ultrasonography ; Uterine Neoplasms