1.A Case of Uterine Prolapse in Pregnancy.
Yun Hyeon HWANG ; Young Seok CHO ; Yong Min KIM ; In Hyun KIM ; Chung Woong KAY ; Chung No LEE
Korean Journal of Perinatology 1999;10(4):524-527
Uterine prolapse with pregnancy is rare condition. The overall incidence is 1/10000- 15000 deliveries. The complications from uterine prolapse range from minor cervical ulceration and infection to fetal death or uterine rupture. The fetal mortality was as high as 22% mainly due to prematurity, respiratory infection. The management of this condition is focused on preventing late occurrence of prolapse during pregnancy and continued reduction. We present a case of uterine prolapse in pregnancy with a brief review of the literature.
Fetal Death
;
Fetal Mortality
;
Incidence
;
Pregnancy*
;
Prolapse
;
Ulcer
;
Uterine Prolapse*
;
Uterine Rupture
2.Sacral pressure sore treatment with gluteal perforator-based flap.
Gyu Suk HWANG ; Won Min YOO ; Eul Je CHO ; Kwan Chul TARK ; Beyoung Yun PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(4):673-678
Sacral pressure sores have been treated by a variety of surgical methods. complete treatment needs wide excision and coverage with healthy tissue which has constant and sufficient blood supply. Use of gluteus maximus muscle flap with or without overlying skin is a revolutionary method because of the reliability of blood supply. However, it is technically a little bit complicated, and future reconstruction for recurrent decubitus is especially limited in paraplegic patients. The development of gluteal perforator-based flap with para-sacral perforator introduce a new treatment modality for the sacral pressure sores. Total 10 cases of sacral pressure sores were treated with gluteal perforator-based flap. There were minimal postoperative complications except wound dehiscence in one case. This flap has a many advantage of no transection or sacrifice of the gluteus maximus muscle, elevation time for the flap is short, reliable blood flow of the perforator, large rotation arc and no post-operative hindrance to walking in patients who are not paraplegic. The disadvantages of this perforator-based flaps are the anatomical variation in the location of perforators and the need for technically careful dissection.
Humans
;
Postoperative Complications
;
Pressure Ulcer*
;
Skin
;
Walking
;
Wounds and Injuries
3.A case of rupture of the common carotid artery by gunshot injury.
Hwang Min YUN ; Jeong Pyo BONG ; Sang Yoo PARK ; Ki Yeun KIM ; Dong Joon PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):1038-1042
No abstract available.
Carotid Artery, Common*
;
Rupture*
4.Comparison of biocompatibility of four root perforation repair materials.
Min Kyung KANG ; In Ho BAE ; Jeong Tae KOH ; Yun Chan HWANG ; In Nam HWANG ; Won Mann OH
Journal of Korean Academy of Conservative Dentistry 2009;34(3):192-198
This study was carried out in order to determine in vitro biocompatibility of white mineral trioxide aggregate (MTA), and to compare it with that of the commonly used materials, i. e. calcium hydroxide liner (Dycal), glass ionomer cement (GIC), and Portland cement which has a similar composition of MTA. To assess the biocompatibility of each material, cytotoxicity was examined using MG-63 cells. The degree of cytotoxicity was evaluated by scanning electron microscopy (SEM) and a colorimetric method, based on reduction of the tetrazolium salt 2,3 bis {2methoxy 4nitro 5[(sulfenylamino) carbonyl] 2H tetrazolium hydroxide} (XTT) assay. The results of SEM revealed the cells in contact with GIC, MTA, and Portland cement at 1 and 3 days were apparently healthy. In contrast, cells in the presence of Dycal appeared rounded and detached. In XTT assay, the cellular activities of the cells incubated with all the test materials except Dycal were similar, which corresponded with the SEM observation. The present study supports the view that MTA is a very biocompatible root perforation repair material. It also suggests that cellular response of Portland cement and GIC are very similar to that of MTA.
Acrylic Resins
;
Aluminum Compounds
;
Calcium Compounds
;
Calcium Hydroxide
;
Drug Combinations
;
Glass Ionomer Cements
;
Glutamates
;
Guanine
;
Humans
;
Hydroxides
;
Microscopy, Electron, Scanning
;
Minerals
;
Oxides
;
Silicates
;
Silicon Dioxide
;
Pemetrexed
5.In Vitro Effect of Liposome-mediated Combined p16 and p53 Gene Transfer to the Human Glioblastoma Cell Lines.
Chang Hyun KIM ; Jeong Taik KWON ; Byung Kook MIN ; Sung Nam HWANG ; Do Yun HWANG ; Duck Young CHOI
Journal of Korean Neurosurgical Society 2002;31(2):152-160
OBJECTIVE: To overcome the limitations of the single gene transfer, the authors present the results of wild-type p16 and p53 combined genes transfer in vitro to the U251MG and U373MG cell lines using cationic liposome as a vector. METHODS: To compare the therapeutic effect of the combined p16 and p53 genes transfer with the single p16 and p53 gene transfer, full length of wild-type human p16 and p53 gene, and combined p16-p53 genes were transferred in vitro to the U251MG and U373MG cell lines using cationic liposome as a vector. As the U251MG and U373MG cell lines are devoid of p16 and p53 genes, the therapeutic effect of the three groups of gene transfer could be evaluated by the growth suppression or percentage of the viable cells. Reverse transcription polymerase chain reaction(RT-PCR), flow cytometry, and electron microscopy(EM) were used for evaluation of the growth suppression or apoptosis of the tumor cells. RESULTS: p16 gene, p53 gene and the combined p16-p53 genes were effectively transferred to the cell lines using cationic liposome as a vector resulting in dramatic decrease of the viable tumor cells in comparison to the control group(p=0.004). The cytotoxic effect of the gene transfer in the U251MG cell line was the most significant in the combined p16-p53 group. However, in the U373MG cell line p53 single gene transfer group showed more significant effect than the combined gene transfer group. Apoptosis was confirmed by EM in the combined p16-p53 genes group. The G1 phase arrest effect, confirmed by the flow cytometry was more prevalent in the p16 gene transfer group than the other groups. CONCLUSION: Cationic liposome-mediated transfer of combined p16-p53 genes to the human glioblastoma cell lines is proven effective. However, the therapeutic effect of the combined p16-p53 genes transfer was not consistently superior to the single p16 or p53 gene transfer.
Apoptosis
;
Cell Line*
;
Flow Cytometry
;
G1 Phase
;
Genes, p16
;
Genes, p53*
;
Glioblastoma*
;
Humans*
;
Liposomes
;
Reverse Transcription
6.Revision of Nutrition Quotient for Korean adults: NQ-2021
Sung-Min YOOK ; Young-Suk LIM ; Jung-Sug LEE ; Ki-Nam KIM ; Hyo-Jeong HWANG ; Sehyug KWON ; Ji-Yun HWANG ; Hye-Young KIM
Journal of Nutrition and Health 2022;55(2):278-295
Purpose:
This study was undertaken to revise and update the Nutrition Quotient (NQ) for Korean adults, a tool used to evaluate dietary quality and behavior.
Methods:
The first 31 items of the measurable food behavior checklist were adopted based on considerations of the previous NQ checklist, recent literature reviews, national nutrition policies, and recommendations. A pilot survey was conducted on 100 adults aged 19 to 64 residing in Seoul and Gyeonggi Province from March to April 2021 using a provisional 26-item checklist. Pilot survey data were analyzed using factor analysis and frequency analysis to determine whether checklist items were well organized and responses to questions were well distributed, respectively. As a result, the number of items on the food behavior checklist was reduced to 23 for the nationwide survey, which was administered to 1,000 adults (470 men and 530 women) aged 19 to 64 from May to August 2021. The construct validity of the developed NQ (NQ-2021) was assessed using confirmatory factor analysis, linear structural relations.
Results:
Eighteen items in 3 categories, that is, balance (8 items), moderation (6 items), and practice (4 items), were finally included in NQ-2021 food behavior checklist. ‘Balance’ items addressed the intake frequencies of essential foods, ‘moderation’ items the frequencies of unhealthy food intakes or behaviors, and ‘practice’ items addressed eating behaviors. Items and categories were weighted using standardized path coefficients to calculate NQ-2021 scores.
Conclusion
The updated NQ-2021 appears to be suitable for easily and quickly assessing the diet qualities and behaviors of Korean adults.
7.Ureterocystoplasty: Experiences in Two Cases of Posterior Urethral Valve.
Jong Min YUN ; Ahnkie LEE ; Moon Soo PARK ; Kwang Myung KIM ; Hwang CHOI
Korean Journal of Urology 1997;38(11):1253-1258
Ureterocystoplasty is a known useful method for the management of selected cases with dilated ureters, high pressure and poorly compliant bladders. It precludes the potential complications of enterocystoplasty. In two cases of posterior urethral valve with urinary incontinence, bilateral dilated ureters, and poorly compliant bladders, we performed ureterocystoplasties using dilated lower end of the ureter after transuretero-ureterostomy and ureteral reimplantation. Both patients were almost continent day and night. The bladder capacities and compliances were improved. There was no deterioration of renal functions. In conclusion, we suggest that the ureterocystoplasty using dilated distal ureter after transureteroureterostomy is an appropriate procedure in selected cases of posterior urethral valve.
Humans
;
Replantation
;
Ureter
;
Urinary Bladder
;
Urinary Incontinence
8.Therapeutic Laparoscopy for Impalpable Testis.
Ahnkie LEE ; Jong Min YUN ; Moon Soo PARK ; Hwang CHOI
Korean Journal of Urology 1997;38(8):848-854
Management of impalpable testis is one of the most controversial issues in cryptorchidism. There is wide variation in approach to this subset of patients. In the child with an impalpable testis, laparoscopy is increasingly used as the diagnostic study of choice. We have recently extended its value by using it as a therapeutic tool. Ten laparoscopic surgical procedures were performed in 10 patients with 12 intra-abdominal testes. In 2 adults with a small intra-abdominal testis and normal contralateral testis, laparoscopic orchiectomy was performed. In 3 patients with 5 intra-abdominal testes, the first phase of two-stage Fowler-Stephens orchiopexy was performed. These patients underwent an open surgical procedure three or four months later. In 3 patients, one stage orchiopexy was performed without dividing the spermatic vessels. In 2 Patients these testes could be mobilized after division of the spermatic vessels (laparoscopic one-stage Fowler-stephens orchiopexy). follow-up ranged from 3 months to 35 months (mean 16.8 months). At follow up 9 of 10 testes (90%) are in the scrotum without atrophy, while 1 (10%) is atrophic. Our early results suggest that increased experience will allow laparoscopic surgery to be a valuable option in the treatment of impalpable testis
Adult
;
Atrophy
;
Child
;
Cryptorchidism
;
Follow-Up Studies
;
Humans
;
Laparoscopy*
;
Male
;
Orchiectomy
;
Orchiopexy
;
Scrotum
;
Testis*
9.A Clinical Experience in 16 Pregnancies with Hemolysis, Elevated Liver Enzymes, and Low Platelets (HELLP Syndrome).
Dong Min LEE ; Sung KIM ; Ho Young KIM ; Jae Yun KIM ; Young Ryoul CHOI ; Jae Kyoung YOO ; In Su HWANG
Korean Journal of Obstetrics and Gynecology 1999;42(9):1903-1908
OBJECTIVE: Our purpose was to describe the clinical progress and the maternal and fetal outcome in 16 pregnancies complicated by the HELLP(hemolysis, elevated liver enzymes, low platelet). Material: We reviewed the maternal and neonatal charts from 16 consecutive pregnancies complicated by the HELLP syndrome among 302 pregnancies complicated by preeclamsia and eclamsia managed at our hospital during the period of 4 years from June 1994 through June 1998. The HELLP syndrome was defined by previously published laboratory criteria. We assessed the time of onset, presenting symptom, laboratory finding, mode of delivery, fetal and maternal complication in each case. We also reviewed the clinical finding in detail in the case resulted in maternal death. RESULTS: In regards to the time of onset, 15 cases (93.7%) occurred at antepartum period and only 1 case (6.2%) occurred at postpartum period. Among the 15 cases occurred at antepartum period, 13 cases (81.25%) developed at 27 to 36 weeks gestation and 2 cases (12.5%) developed at near term. In regards to the presenting symptom, twelve patients (75%) complained of right upper quardrant or epigastric pain. Of 16 patients, 12 patients (75%) experienced headache and 10 patients (62.5%) complained of nausea, or vomiting and 5 patients (31.2%) had visual disturbance. The laboratory finding of all 16 cases were as follow; the mean level of platelet: 68700/mm3 (range: 48000 to 91700), the mean level of serum asparate aminotransferase: 335 IU/L (range: 62 to 135), the mean level of lactic dehydrogenase: 910 IU/L (range: 558 to 5794), and the mean level of total bilirubin: 2.6 mg/dl (range: 0.7 to 10.4). To review the mode of delivery, cesarean sections were done on 10 patients (62.5%) including 7(43.7%) emergency and 3(18.7%) elective operations. However, 6 patients (37.5%) delivered vaginally. Maternal complications were as follow; abruptio placenta in 1 case (6.2%), DIC in 2 cases (12.5%), pulmonary edema in 3 cases (18.7%), pleural effusion in 4 cases (25%), renal failure in 4 cases (25%), and 1 case of death. Fetal and neonatal outcome was assessed; 9 cases of intrauterine growth retardation (56.2%), meconium stained in 3 cases (18.7%), 2 stillbirth (12.5%), and 2 neonatal death (12.5%). CONCLUSION: HELLP syndrome is associated with serious maternal and fetal morbidity and mortality.
Bilirubin
;
Blood Platelets
;
Cesarean Section
;
Dacarbazine
;
Emergencies
;
Female
;
Fetal Growth Retardation
;
Headache
;
HELLP Syndrome
;
Hemolysis*
;
Humans
;
Liver*
;
Maternal Death
;
Meconium
;
Mortality
;
Nausea
;
Oxidoreductases
;
Placenta
;
Pleural Effusion
;
Postpartum Period
;
Pregnancy*
;
Pulmonary Edema
;
Renal Insufficiency
;
Stillbirth
;
Vomiting
10.The Effect of Hydroxyl Radical Generation on the Cytotoxicity of Alveolar Macrophage and Lipid Peroxidation of Erythrocyte Membrane by Mineral Fibers.
Kyoung Ah KIM ; Young LIM ; Ji Hong KIM ; Hwang Sin CHANG ; Chung Yill PARK ; Im Goung YUN ; Min Hwa OH
Korean Journal of Occupational and Environmental Medicine 1997;9(3):401-410
No abstract available.
Erythrocyte Membrane*
;
Erythrocytes*
;
Hydroxyl Radical*
;
Lipid Peroxidation*
;
Macrophages, Alveolar*
;
Mineral Fibers*