No abstract available.
Blood Platelets* ; Diagnosis* ; Flow Cytometry* ; Integrin beta3* ; Thrombasthenia*

No abstract available.
Endometriosis* ; Female

No abstract available.
Genes, myc* ; Neuroblastoma* ; Polymerase Chain Reaction*

Benign and malignant papillary neoplasms of the breast may be difficult to distinguish in both cytologic and histologic preparations. To define the cytologic features of benign and malignant papillary lesions, we retrospectively reviewed 18 cases of fine needle aspirates from histologically confirmed cases of papilloma or papillary carcinoma of the breast. This study included 3 intraductal papillary carcinomas, 3 invasive papillary carcinomas, and 12 intraductal papillomas. All cases were evaluated for presence or absence of papillary fragments, bloody background, apocrine metaplasia, macrophages, and degree of cellularity, atypia, and single isolated columnar epithelial cells. Papillary fragments were present in all cases. The background of the smear was bloody in all 6 carcinomas, but in only 7 out of 12 papillomas. Markedly increased cellularity was present in 4 carcinomas (67%) and 7 papillomas (58%). Single cells were present in 5 carcinomas (83%) and 8 papillomas (67%). The majority of papillomas and papillary carcinomas had mild to moderate atypia, and severe atypia was noted in one case of intraductal papillary carcinoma and one case of invasive papillary carcinoma. Apocrine metaplasia was absent in all cases of papillary carcinomas, but present in 8 papillomas (67%). Macrophages were noted in 4 carcinomas and were present in all cases of papillomas. The constellation of severe atypia, bloody background, absence of apocrine metaplasia and/or macrophages were features to favor carcinoma. Malignant lesions tended to show higher cellularity and more single isolated cells. The cytologic features mentioned above would be helpful to distinguish benign from malignant papillary lesions of the breast. However, because of overlapping of cytologic features, surgical excision should be warranted in all cases of papillary lesions of the breast to further characterize the tumor
Breast ; Carcinoma, Papillary ; Central Nervous System* ; Cyclosporine* ; Epithelial Cells ; Macrophages ; Metaplasia ; Needles ; Papilloma ; Papilloma, Intraductal ; Retrospective Studies

PURPOSE: This study was performed to understand health perception, health practice, and depression of the elderly and to identify their depression level according to health perception and health practice. METHOD: The subjects were 463 elders who have lived in the Jeju Island, and data were collected from June to August in 2005. Data were analyzed by SPSS 10.0. RESULT: The mean score of depression was 12.94 out of 30, and had a statistically significant correlation with educational level (F=2.943, p=.033), occupation (F=4.611, p=.010), and the number of chronic diseases (F=5.303, p=.001). When the cutoff of 18 points was applied based on Jung et al. (1997), the depression ratio was 12.4%, and when the cutoff parameter by Yesavage et al (1993) was applied, themoderate depression ratio was 74.8% and the severe depression ratio was 3.4%. In health recognition, consideration of usual health state had a significant correlation with depression (F=3.553, p=.007), but consideration of health state compared to the previous year wasn't. In health practice, sleeping was in a significant correlation with depression (F=3.574, p=.011), but smoking, alcohol drinking, exercise, and rest were not. CONCLUSION: Based on above results, we need further study on another sample group and the development, application, and verification of health management, education, and counseling programs for the elderly. Also, additional research should be made on significant factors of elderly depression.
Aged ; Alcohol Drinking ; Chronic Disease ; Counseling ; Depression* ; Education ; Humans ; Occupations ; Smoke ; Smoking

PURPOSE: The aim of this study was to describe the experiences of student nurses during their clinical practice periods in an alcoholic ward. METHODS: A descriptive phenomenological study design was employed. Individual interviews were conducted and audio-taped. Colaizzi's method of data analysis was applied to inductively determine themes and formulated meanings. Data saturation was achieved and methodological rigor was established. RESULTS: Four themes were identified and these themes included anxiety of nursing practice in unfamiliar setting, sympathy with patients, learning about the inpatient alcoholics care, and self-reflection. CONCLUSION: Nursing students had positive and negative experiences in their clinical practice. The results of this study had important implications regarding clinical practice and research for nursing clinical education.
Alcoholics ; Alcoholism* ; Anxiety ; Education ; Humans ; Inpatients ; Learning ; Nursing ; Private Practice ; Qualitative Research ; Statistics as Topic ; Students, Nursing*

PURPOSE: The aim of this study was to assess the efficacy of web-based simulation and high-fidelity simulation on acute heart disease patient care. METHODS: The project used a comparative study design with two simulation-based training modalities. A total of 144 nursing students participated in this study: 76 students in a web-based simulation, and 68 students in a high-fidelity simulation. Participants rated their self-efficacy, problem-solving ability, interest in learning, level of stress, satisfaction with the simulation experience, and level of difficulty of the simulation. RESULTS: The scores for self-efficacy, problem-solving ability, and interest in learning including interest in clinical training in the high-fidelity simulation group was higher than in the web-based simulation group. However, there were no significant differences in interest in learning, including interest in nursing knowledge, and in lab training, level of stress, satisfaction with the simulation experience, and level of difficulty of the simulation. CONCLUSION: A high-fidelity simulation of acute heart disease patient care might be beneficial to developing many more abilities for nursing students than would a web-based simulation. Also, since the web-based simulation improved interest in nursing knowledge, it could be a viable alternative to high-fidelity simulation. Further study is needed to verify the effects of varied levels of simulation-based care with more rigorous outcomes.
Heart Diseases* ; Heart* ; Humans ; Learning ; Nursing ; Patient Care* ; Simulation Training ; Students, Nursing

BACKGROUND: To access the accuracy and clinical usefulness of microplate identification (ID) system for the identification of Enterobacteriaceae, we compared microplate ID system with API 20E(bioMerieux, Etoile, France). METHODS: Ninety-two cultures of Enterobacteriaceae and one isolate of Aeromonas species were simultaneously identified by microplate ID system and the API 20E. Twenty biochemical tests used in microplate ID system were lactose, sucrose, and H2S in Kligler's iron agar media; indole, sucrose, raffinose, arabinose, trehalose, adonitol, dulcitol, sorbitol, cellibiose, methy-red, phenylalanine deaminase, ornithine decarboxylase, lysine decarboxylase, arginine dihydrolase, urease, and citrate in microplate; and oxidase test. The identification was obtained by considering percent likelihood(% ID), modal frequency and ID score method. RESULTS: Among the 92 cultures of Enterobacteriaceae and one isolate of Aeromonas species, agreement rate of identification according to the % ID between microplate ID system and API 20E were 90.3% to the species level and 97.8% to the genus level. CONCLUSIONS: For the identification of clinical Enterobacteriaceae isolates, the microplate ID system compares favorably with API 20E in identification accuracy and have the advantage of costsaving and easy to use.
Aeromonas ; Agar ; Arabinose ; Arginine ; Citric Acid ; Enterobacteriaceae* ; Galactitol ; Iron ; Lactose ; Lysine ; Ornithine Decarboxylase ; Oxidoreductases ; Phenylalanine ; Raffinose ; Ribitol ; Sorbitol ; Sucrose ; Trehalose ; Urease

PURPOSE: The aim of this study was to develop course outcomes for nursing students by applying Hauenstein's theory. METHODS: The research was conducted in three steps as follows: identifying exit outcomes related to the Adult Nursing course, developing Adult Nursing course outcomes based on the theory of Hauenstein, and finalizing Adult Nursing course outcomes. RESULTS: Exit outcomes achievable in Adult Nursing were generated after a needs analysis survey among students, nurses and professors was conducted and subsequently reviewed by professors specializing in the subject. For theoretical courses, the level of the course outcomes was derived from the cognitive domain, whereas, for practical courses, it was derived, in stages, from the cognitive, affective and psychomotor domains. Next, using taxonomical terms that can properly address the level of each domain, course outcomes for theoretical and practical courses were determined. After expert opinion was sought, the final course outcome for the Adult Nursing course was produced. CONCLUSION: The results are meaningful in that valid course outcomes were developed through the process described above and are expected to greatly contribute to reaching exit outcomes and strengthen the professional capacity of nursing students.
Adult ; Expert Testimony ; Humans ; Learning ; Nursing ; Students, Nursing

No abstract available.
Arthritis, Rheumatoid* ; Humans ; Hyperplasia* ; NF-kappa B*