1.Kawasaki Disease.
Yeungnam University Journal of Medicine 2000;17(2):99-107
Kawasaki disease, an acute febrile illness which primarily affects in children under the age of six, was first described by Tomisaku Kawasaki in 1967. It has been reported that Kawasaki disease is probable driven by abnormalities of the immune system after an infectious insult, but this has not been confirmed. It mainly affects small and medium-sized arteries, particularly the coronary arteries. Deaths may occur at any time with cardiovascular complications. The early recognition and treatment with follow-up evaluation for the coronary arterial lesion is very important in a case of Kawasaki disease.
Arteries
;
Child
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Coronary Vessels
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Humans
;
Immune System
;
Mucocutaneous Lymph Node Syndrome*
;
Prognosis
2.Cinical Study of Spontaneous Closure in Simple Ventricular Septal Defects.
Young Hwan LEE ; Yong Hoon PARK
Yeungnam University Journal of Medicine 1995;12(1):105-112
During the period of 9.5 years from September, 1985 to March, 1995, 32 cases with spontaneous closure in simple ventricular septal defect(VSD) were observed and evaluated at Yeungnam University Hospital, and those were confirmed by 2D-echocardiogram. The results were as follows: 1. Among these 32 cases, there were 23 cases(71.9%) of perimembranous VSD, 8 cases(25.0%) of muscular VSD and 1 case(3.1%) of subarterial VSD. Septal aneurysms appears to be main mechanism of spontaneous closure of VSD because of the presence of septal aneurysm in all cases with spontaneous ',;losure of a perimembranous VSD. 2. The size of the defect was variable in diameter, but 27 cases(81.2%) were less than 5 mm. 3. The mean age was 12.1 months at spontaneous closure with the range from 1 month old to 72 months. 4. The mean weight was 9.0 kg at spontaneous closure. 5.--Among these 32 cases, 3 cases had the clinical evidence of cardimegaly or congestive hert -failure during infancy. 6. Male to female sex ratio was 1.5:1
Aneurysm
;
Estrogens, Conjugated (USP)
;
Female
;
Heart Septal Defects, Ventricular*
;
Humans
;
Male
;
Sex Ratio
3.Treatment of PDA in premature newborns with mefenamic acid.
Jae Joon LEE ; Young Hwan LEE ; Son Moon SHIN
Yeungnam University Journal of Medicine 1993;10(2):506-511
This study was conducted to examine the effect of mefenamic acid for treatment of PDA in premature newborns. Ductus arteriosus is reopened by locally produced prostaglandin E2 in a premature newborn during hypoxia. Mefenamic acid is one of non-steroidal antiinflammatory drugs acting by inhibition of cyclo-oxygenase in the prostaglandin synthesis pathway. For three premature newborns with PDA, we administered mefenamic acid and evaluated them with echocardiography to study the effect of mefenmic acid for closure of PDA. In all three babies, ductus arteriosus was closed successfully. We feel that mefenamic acid is safe and effective medication for treatment of PDA in premature newborns, but further-study need to be conducted with larger numbers of cases to confirm this effect.
Anoxia
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Dinoprostone
;
Ductus Arteriosus
;
Echocardiography
;
Humans
;
Infant, Newborn*
;
Mefenamic Acid*
;
Prostaglandin-Endoperoxide Synthases
4.Two cases of cyclopia in twin.
Joon Soo PARK ; Si Hwan KHO ; Dong Hwan LEE ; Sang Jhoo LEE ; So Young JIN
Journal of the Korean Pediatric Society 1991;34(5):700-706
5.Present status of correction and causes of delay in cryptorchid patients.
Dong Hwan LEE ; Young Lae CHO ; Hong Jin SUH
Journal of the Korean Academy of Family Medicine 1997;18(9):936-942
BACKGROUND: If the corrections of the cryptorchid testes are delayed, it may lead the patients to suffer loss of testes or fertility. So we purposed to analyze the present status of correction and the causes of delay and tried to emphasize the needs to educate and inform the ideal age for correction. METHODS: Total 363 cryptorchid patients who visited our hospital in 10 years from January 1987 to December 1996 were divided into 3 groups according to their ages at visit as under 2, 3 to 5 and over 6 years groups. We analyzed the operative findings of the 3 groups, compared the ratio of the over 6 group during the half ten years till 1991 to the same ratio after 1992 and also analyzed the causes of delay in 81 patients for whom the causes of delay could be identified in over 6 years group. RESULTS: The age distributions showed 88 patients(24.2%) of under 2 years group, 118 patients(32.5%) of 3 to 5 years group and 157 patients(43.3%) of over 6 years group. When we compare the former 5 years till 1991 to the latter 5 years after 1992, the number of the patients who underwent orchiopexy under the age of 2 were increased from 34 (19.1%) to 54(29.2%) and those over the age of 6 were decreased from 88(49.4%) to 69 (37.3%) but still in higher proportion. The intraoperative findings showed that the rate of atropic or smaller testes than normal size in over 6 years group(128 testes, 73.1%) were higher than those of under 2 years(10 testes, 9.8%) and 3 to 5 years group(28 testes, 20.2 %). The most common causes of delay in over 6 years group was recommendation by relatives or neighbors(36 patients, 48.1%) and the remainders were advices of doctors other than urologists(27 patients, 33.3%), poor economic status(8 patients, 9.9%) and unawareness of the anomaly(7 patients, 8.6%). CONCLUSIONS: To prevent the loss of testicular function or testis itself in patient with cryptorchidism, the early correction should be performed because the recommended age for the correction tends to be decreased. The public information for the recommended age should be provided and also educational programs for the primary physicians are supposed to be performed.
Age Distribution
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Cryptorchidism
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Fertility
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Humans
;
Male
;
Orchiopexy
;
Testis
6.A STUDY ON ACCUARACY AND DIMENSIONAL STABILITY ACCORDING TO IMPRESSION METHODS.
Jae Young LEE ; Ju Hwan LIM ; In Ho CHO
The Journal of Korean Academy of Prosthodontics 1999;37(5):567-580
Accurate reproduction of intraoral tissue is essential in the fabrication of fixed prosthesis. This selection of impression material and method is very important. In this study, vinyl polysiloxane type impression material Panasil was used. Three impression methods ; one-step technique, individual tray technique, and individual tooth tray technique using the vinyl polysiloxane type bite registration material Futar Occlusion, were used to take horizontal and vertical impression. Improved stone models were fabricated. The amount of occlusal surface discrepaneies, interabutment distance discrepancies, amount of marginal defect were evaluated with the X-PLAN360d and photoscanning. The results were as follows. 1. There was no significant difference in occlusal surface according to the directions and techniques of impression taking. 2. There was no significant difference in interabutment distance discrepancies according to the directions and techniques of impression taking 3. There was no significant difference in marginal discrepancies according to the direction of impression taking but there was significant difference between one-step technique and individual tray technique, individual tooth tray technique (P<0.05). Taken together, these results suggest that individual tray technique and individual tooth tray technique are more accurate for impression taking than one-step technique.
Jaw Relation Record
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Prostheses and Implants
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Reproduction
;
Siloxanes
;
Tooth
7.A subclassification of conduct disorder by child behavior checklist.
Hwan Bae LEE ; Young Sook KWACK ; Ki Chung PAIK
Journal of Korean Neuropsychiatric Association 1992;31(2):351-362
No abstract available.
Checklist*
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Child
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Child Behavior*
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Child*
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Conduct Disorder*
;
Humans
8.Experimental proliferative vitreoretinopathy.
Young Hoon PARK ; Bong Hwan LEE ; Duk Kee HAHN
Yeungnam University Journal of Medicine 1991;8(1):178-190
The authors performed experimental study to produce proliferative vitreoretinopathy by intravitreal injection of homologous fibroblasts in pigmented rabbits. Twenty four eyes of 12 rabbits were divided into control and experimental groups. In experimental group, the eyes were pretreated with expanding gas, perfluoropropane for the vitrectomy. In control group, no such procedure was preceded. In both groups, 5.0×10⁴, 1.0×10⁵ and 1.5×10⁵ cells of homologous fibroblasts were injected into the vitreous cavity. All the eyes were observed regularly with indirect ophthalmoscope followed by fundus photography. Those eyes were enucleated in 1, 2, 4 weeks for the light and electron microscopic studies. The development and severity of the proliferative vitreoretinopathy were correlated with the numbers of the injected fibroblast. This was more pronounced in the experimental group.
Fibroblasts
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Intravitreal Injections
;
Ophthalmoscopes
;
Photography
;
Rabbits
;
Vitrectomy
;
Vitreoretinopathy, Proliferative*
9.Presence of E-cadherin in Cultured Amnionic Cells.
Ki Hwan LEE ; Young Suk SEO ; Kil Chun KANG
Korean Journal of Obstetrics and Gynecology 1999;42(12):2690-2694
OBJECTIVES: Cell adhesion molecules may play a role in integrating amnionic membrane. The objective of this study was to prove E-cadherin mRNA and proteins in cultured human amnionic cells. METHODS: We cultured amnionic cells from 4 women undergoing cesarean section without labor. E-cadherin was determined by immunohistochemistry and Western ligend blotting. To demonstrate E-cadherin mRNA, reverse transcription-polymerase chain reaction was performed. RESULTS: On immunohistochemistry, E-cadherin was abundantly showed on the cytoplasm of the cells. Western ligend blotting showed clear 120 kDa bands on four specimens, and relatively weak band on one specimen. Reverse transcription-polymerase chain reaction showed 432 BP bands. CONCLUSION: We proved E-cadherin and its mRNA by immunohistochemistry, Western ligend blotting and reverse transcription-polymerase chain reaction in cultured human amnionic cells.
Amnion*
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Cadherins*
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Cell Adhesion Molecules
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Cesarean Section
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Cytoplasm
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Female
;
Humans
;
Immunohistochemistry
;
Membranes
;
Pregnancy
;
RNA, Messenger
10.NASAL PACKING WITH "THE TUBED MEROCEL" AND "THE FINGER STALL" AFTER CLOSED REDUCTION OF NASAL BONE FRACTURE.
Dong Hwan JO ; Kyung Mok KIM ; Young Seob LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1012-1015
No abstract available.
Fingers*
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Nasal Bone*