1.Identification of Korean victims in PMT-air airplane crash accident.
Sang Seob LEE ; Joong Seok SEO ; Mun Hwan KANG
Korean Journal of Legal Medicine 2007;31(2):157-161
The PMT-air airplane crash accident occurred in June 25, 2007 in Sihanoukville, Cambodia. All 22 passengers and crew, including 13 Korean victims, were found dead. Human identification was done at the Cambodian-Russian Soviet friendship hospital. All of Korean victims were identified with fingerprint comparison, age estimation, comparison of belongings and examination of past medical history. In this identification process, the examination of antemortem data source with searching personal blog of internet had been proved efficient in human identification. The antemortem data collection with internet access may be useful and should be combined with classical antemortem data collection process because it is beyond spatial and time limitation.
Aircraft*
;
Blogging
;
Cambodia
;
Information Storage and Retrieval
;
Dermatoglyphics
;
Forensic Anthropology
;
Friends
;
Humans
;
Internet
2.Pulmonary Mucinous Cystic Tumor of Borderline Malignancy: A case of report.
Gyung Min KANG ; Yong Taek LIM ; Chul Hwan KIM ; Seob LEE ; Yong HUR ; Byung Yeol KIM ; Jung Ho LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1998;31(2):212-215
Pulmonary mucinous cystic tumor of borderline malignancy is very rare and distinguished from bronchogenic cyst or adenocarcinoma of bronchoalveolar type. We present the case of a 63-year-old woman with a right lower lobe mass, found by chest radiographs. The preoperative diagnosis was made as bronchoalveolar cancer by percutaneous needle aspiration of mass. Right lower lobectomy and lymph node dissections were performed. The lobectomy specimen contained variable sized multilocular cystic mucous masses, filled with mucus. Microscopically, the cystic masses are lined with tall columnar mucinous epithelium but some area contains focal cellular atypism and bronchoalveolar cancer like foci. This foci are lack of cellular atypism consistent with bronchoalveolar cancer cell. After lobectomy the patient has remained free from recurrence and distant metastasis for following 12 months period. Pulmonary mucinous cystic tumor of borderline malignancy appears to have a favorable prognosis and should be distinguished from other lung neoplasms.
Adenocarcinoma
;
Bronchogenic Cyst
;
Diagnosis
;
Epithelium
;
Female
;
Humans
;
Lung
;
Lung Neoplasms
;
Lymph Node Excision
;
Middle Aged
;
Mucins*
;
Mucus
;
Needles
;
Neoplasm Metastasis
;
Prognosis
;
Radiography, Thoracic
;
Recurrence
3.A Case of Eosinophilic Gastroenteritis with Rapid Deterioration Mimicking Borrmann Type 4 Advanced Gastric Cancer.
Ju Young LEE ; In Sun MIN ; Jung Un HONG ; Tae Seob JUNG ; Bo Bae PARK ; In Young NHO ; Sung Hwan KANG
The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2015;15(4):264-269
Eosinophilic gastroenteritis is an uncommon disease of unknown etiology that is characterized by massive tissue infiltration of eosinophils in the tissue layers of various areas of the gastrointestinal tract. An accurate diagnosis is difficult as clinical presentations, symptoms, endoscopic and radiologic findings are nonspecific. A 51-year-old man visited our hospital presenting with abdominal pain. Esophagogastroduodenoscopy revealed diffuse hyperemic mucosal lesions at the stomach, duodenum. Symptoms and endoscopic findings deteriorated rapidly after three days. Small amounts of eosinophilic infiltration without malignant cells was confirmed from biopsy. However, we could not exclude malignancy and performed a subtotal gastrectomy. Stomach specimen showed eosinophilic infiltrations, and the patient was finally diagnosed as eosinophilic gastroenteritis. We report a case of atypical eosinophilic gastritis with rapid deterioration mimicking Borrmann type 4 advanced gastric cancer.
Abdominal Pain
;
Biopsy
;
Diagnosis
;
Duodenum
;
Endoscopy, Digestive System
;
Eosinophils*
;
Gastrectomy
;
Gastritis
;
Gastroenteritis*
;
Gastrointestinal Tract
;
Humans
;
Middle Aged
;
Stomach
;
Stomach Neoplasms*
5.Re-stooping after Corrective Osteotomy in Patients with Ankylosing Spondylitis
Jin-Sung PARK ; Byeong-Jik KANG ; Tae-Hwan KIM ; Hyung-Seob AHN ; Ye-Soo PARK
Clinics in Orthopedic Surgery 2023;15(1):101-108
Background:
Corrective osteotomy is an effective surgery for correcting posture in patients with ankylosing spondylitis (AS). Despite satisfactory correction, some patients experience re-stooping during follow-up. However, there have been no studies on restooping in AS. We aimed to analyze the factors that affect re-stooping.
Methods:
Fifty patients (50 cases) who underwent thoracolumbar corrective osteotomy for AS from March 2006 to April 2018 were analyzed. We defined re-stooping as global kyphosis that recurs after corrective osteotomy. The patients were divided into two groups based on the ratio of correction loss: non-re-stooping group (N group) and re-stooping group (R group). We analyzed the demographic data and radiological parameters, such as modified Stoke Ankylosing Spondylitis Spine Score (mSASSS), sagittal vertical axis, and various angles. We also investigated the factors affecting re-stooping by analyzing the correlation between the ratio of correction loss and various factors.
Results:
A significant difference was seen in the change in the mSASSS from before surgery to the last follow-up between the N group (2.87 ± 3.08) and the R group (9.20 ± 5.44). In multivariate analysis, only the change in the mSASSS from before surgery to the last follow-up was significantly correlated with the ratio of correction loss.
Conclusions
Thoracolumbar corrective osteotomy seems to provide high satisfaction among patients with AS but can lead to re-stooping during follow-up. The change in mSASSS was related with re-stooping in the current study. We recommend active rehabilitative exercises and appropriate medication depending on the patient’s condition, which may help delay the postoperative progression of AS.
6.MR Imaging Findings of Ring Apophyseal Fractures in Lumbar Vertebrae.
Yong Soo KANG ; Soon Tae KWON ; Chang Joon SONG ; Young Hwan LEE ; Hyoung Seob KIM ; Hwan Do LEE ; June Sik CHO ; Jae Sung AHN ; June Kyu LEE
Journal of the Korean Radiological Society 1997;37(1):145-151
PURPOSE: To assess the location and associated findings of fractures of the posterior lumbar vertebral ring apophysis as seen on MRI. MATERIALS AND METHODS: We retrospectively evaluated MR findings in 77 patients (86 lesions) with lumbar apophyseal ring fractures. Their age ranged from ten to 67 (mean 33-1) years. To confirm the presence of verterbral ring fractures, CT was performed in 29 patients (31 lesions) within two weeks of MR imaging. Open laminectomy was performed in ten patients, percutaneous automated nucleotomy in three, and LASER operation in four. RESULTS: The most common location of fractures was the superior margin of L5 (36 lesions 41.9%), next was superior margin of S1 (21 lesions, 24.4%). On CT, a bony fragment was seen in 28 patients (30 lesions); the positive predictive value of MR was 99.7 %. Multiple lesions were seen in nine patients. Associated disc herniation and bulging were noted in 64 (74.4%) and 15 lesions (17.4%), respectively, and a high signal intensity rim aound the bony fragment on T1 weighted image was noted in 33 (38.4%). Other associated findings were spondylolysis in eight patients, retrolisthesis in five, and spondylolisthesis in three. Operative outcomes were variable. The results of open laminectomy were better than those of percutaneous automated laminectomy or LASER operation. CONCLUSION: In patients with lumbar apophyseal ring fractures, their exact location and associated findings could be evalvated by MRI, which was therefore useful in the planning of appropriate surgery.
Humans
;
Laminectomy
;
Lumbar Vertebrae*
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Spondylolisthesis
;
Spondylolysis
7.Clinical features and serial changes in the indirect immunofluorescent antibody titers by the duration of illness in 28 children with scrub typhus.
Byung Kyoo PARK ; Seung Hwan KIM ; Yung Kyoon OH ; Hee Sang YOON ; Myung Kul UHM ; Han Wook YOO ; Jae Hyung KIM ; Hwan Seob KANG ; Ik Sang KIM ; Woo Hyun CHANG
Korean Journal of Infectious Diseases 1993;25(2):109-123
No abstract available.
Child*
;
Humans
;
Scrub Typhus*
8.The Effectiveness of 6-Month Treatment with Venlafaxine Extended Release in Generalized Anxiety Disorder: Prospective, Multi-Center, Open-Labeled Trial.
Joo Eon PARK ; Jeong Ho CHAE ; Seung Hwan LEE ; Sung Gon RYU ; Chan Hyung KIM ; Kang Seob OH ; Youl Ri KIM ; Bum Hee YU
Korean Journal of Psychopharmacology 2006;17(1):50-59
OBJECTIVE: We aimed to examine the efficacy and the safety of venlafaxine extended release (venlafaxine-XR), and its effect on the quality of life in patients with generalized anxiety disorder. METHODS: Fifty three patients who had generalized anxiety disorder were recruited for this study. They showed scores of 18 or higher on the Hamilton Rating Scale for Anxiety (HAMA) and did not have major depression. They were scheduled to be examined 5 times (at baseline, 4, 8, 16 and 24 weeks) and took venlafaxine-XR for 24 weeks with a flexible dosing schedule. The primary efficacy variables were the response and remission rates (response: more than 50% reduction from baseline in HAMA total score ; remission: HAMA total score< or =7). Other variables were the Hamilton Ratng Scale for Depression, Beck Anxiety Inventory, Sheehan Disabilities Scale (SDS), and World Health Organization Quality of Life Assessment Instrument-Brief Form (WHOQOL-BREF). Also, the evaluation on adverse effects was performed. RESULTS: The number of patients who completed 24 weeks of treatment was 32 (60.4%). Twenty one patients who were dropped out included 8 patients with intolerable adverse effects and 7 patients with unsatisfactory treatment response. Response/remission rates were 43.4/32.1% in the last-observation-carried-forward methods and 71.9/53.1% in the observed case data. Treatment with venlafaxine-XR improved anxiety and depressive symptoms during 24 weeks on all efficacy measures. By a completed patient analysis, venlafaxine-XR also significantly improved the disability scores on SDS and the quality of life scores on WHOQOL-BREF. In this study, nausea, palpitation, and severe tremor were common reasons of venlafaxine-XR discontinuation in GAD patients, but any serious adverse effect did not occur. CONCLUSION: Treatment with venlafaxine-XR was effective and well-tolerated for the patients with GAD, and also improved quality of life in the GAD patients.
Anxiety Disorders*
;
Anxiety*
;
Appointments and Schedules
;
Depression
;
Humans
;
Nausea
;
Prospective Studies*
;
Quality of Life
;
Treatment Outcome
;
Tremor
;
World Health Organization
;
Venlafaxine Hydrochloride
9.The Effectiveness of 6-month Treatment with Citalopram in Korean Panic Disorder Patients: A Prospective, Open-labeled, Multi-Center Trial.
In Soo LEE ; Jong Chul YANG ; Young Hee CHOI ; Jung Bum KIM ; Sang Yeol LEE ; Seung Hwan LEE ; Kang Seob OH ; Bum Hee YU
Korean Journal of Psychopharmacology 2006;17(2):203-211
OBJECTIVE: The authors examined the efficacy of citalopram, and its effect on the quality of life in patients with panic disorder. METHOD: Seventy three patients who had panic disorder were recruited for this study. They did not have major depression and other axis I diseases. They were scheduled to be examined 4 times (at baseline, 4, 12 and 24 weeks) and took citalopram for 24 weeks with a flexible dosing schedule. The primary efficacy variables were the response and remission rates (response: HAMA total score decreased by at least 50% from baseline; remission: HAMA total score < or = 7). Other variables included the Hamilton Rating Scale for Depression, Panic Disorder Severity Scale (PDSS), Acute Panic Inventory, Clinical Global Impression Scale and Sheehan Disabilities Scale (SDS). RESULTS: The number of patients who completed 24 weeks of treatment was 33 (45.2%). Forty patients who were dropped out consisted of 4 patients with symptom improvement and 36 patients with failure to return. Response/remission rates were 56.2/31.5% in the last-observation-carried-forward methods and 87.9/69.7% in the observed case data. Treatment with citalopram improved anxiety and depressive symptoms during 24 weeks on all efficacy measures. By a completed patient analysis, citalopram also significantly improved the disability scores on SDS. In this study, any serious adverse effects were not observed. CONCLUSION: Treatment with citalopram was effective and well-tolerated for the patients with panic disorder, and also improved quality of life in the patients.
Anxiety
;
Appointments and Schedules
;
Axis, Cervical Vertebra
;
Citalopram*
;
Depression
;
Humans
;
Panic Disorder*
;
Panic*
;
Prospective Studies*
;
Quality of Life
;
Treatment Outcome
10.Differential Effects of Antipsychotic Drugs on Dopamine D1 and D2 Receptor mRNAs in the Rat Brain.
Myeong Ok KIM ; Yoon Sook KIM ; Chang Hwan PARK ; Young Ae YANG ; Sang Soo KANG ; Gyeong Jae CHO ; Gu Seob ROH ; Wan Sung CHOI
Korean Journal of Anatomy 2005;38(4):363-370
The principal aim of this study was to determine the effects of antipsychotics (haloperidol, sulpiride, and clozapine) on regulating dopamine (DA) D1 and D2 receptor mRNA levels in the rat caudate putamen (CPu), nucleus accumbens (NAc), and olfactory tubercle (OTu). Twenty male Sprague-Dawley rats (250 g) were treated with haloperidol (1mg/mL), sulpiride (40 mg/mL), clozapine (20 mg/mL), and the control group received only water. Drugs were administered orally for 4 weeks. Antipsychotic drugs had differential effects on DA D1 and D2 receptor gene expression. Haloperidol and sulpiride induced an increase of DA D1 and D2 receptor mRNA levels in the rat CPu, OTu, and NAc; haloperidol caused a greater increase than sulpiride. However, clozapine treatment had less effect on DA receptor mRNAs levels in the same area. Antipsychotic drugs differentially upregulated the expression of DA D1 and D2 receptor mRNAs in the rat brain. These changes may be related, at least in part, to changes of DA concentration following antipsychotics treatment.
Animals
;
Antipsychotic Agents*
;
Brain*
;
Clozapine
;
Dopamine*
;
Gene Expression
;
Haloperidol
;
Humans
;
In Situ Hybridization
;
Male
;
Nucleus Accumbens
;
Olfactory Pathways
;
Putamen
;
Rats*
;
Rats, Sprague-Dawley
;
Receptors, Dopamine
;
RNA, Messenger*
;
Sulpiride
;
Water