Between September to October 1985, 61 male patients with uncomplicated genital gonorrhea, including 33 PPNG urethritis, were treated with single oral dose of rosoxaci, a new oral quinolone derivative, 300 mg Fifty-three patients returned for a test of cure 3 5 days after the treatment. When a patient was found to be not cured, a second course of treatment was given and followed as above. The overall failure rate of initial treatment was 11.3%(6/53). It was 15. 2%(5/33) for PPNG urethritis and 5%(1/20) for non-PPNG urethritis. During the course of this trial the rate af PPNG among pretreatment isolates was exceptionally high(62.2g) compared to 277. during the period of 198l~4. If the PPNG prevalance rate had been a little lower, for instance 30g the overall failure rate would have been much lower(4.9%). When the second treatment was given to the failure cases 4-6 days after the first treatment. The overall failure rate dropped to 3.8%, 3.1% for PPNG urethritis and 5.0% for non-PPNG urethritis. Ten patients (2l, 3p,) developed postgoriococcal urethritie. Susceptibility test, with disks containing rosoxacin 5mcg, showed the inhibition zone to be greater than 34mm. Eight patients developed minor side effects: dizziness or gastritis. The rosoxacin, oral dose of 300 mg, regimen gave the best result yet by oral treatment for gonorrheae in recent years in Korea.
Dizziness ; Gastritis ; Gonorrhea ; Humans ; Korea ; Male* ; Urethritis*

No abstract available.
Female ; Methotrexate* ; Pregnancy ; Pregnancy, Tubal*

A case of benign lichenoid keratosis(BLK) developed in a 25-year-old female is presented. She had two erythematous plaques with slightly verrucous surfaces on the lips for 4 weeks. A biopsy specirnen taken from the periphery of the lesion revealed a focal parakeratosis, the absence of granular cells, and hydropic degeneration of the basal cells in the epidermis. The upper dermal infiltrate composed chiefly of lymphacytes intermingled with a few histiocytes was also seen. The direct immunofluorescent study showed depositions of a few cytoid bodies and fibrin around the areas of the dermoepidermal junction. These plaques on her lips, demonstrating lichenoid tissue changes, cleared in 8 weeks from the evalution, without any treatment.
Adult ; Biopsy ; Epidermis ; Female ; Fibrin ; Histiocytes ; Humans ; Keratosis* ; Lip ; Parakeratosis

No abstract available.
Female ; Follicle Stimulating Hormone* ; Gonadotropin-Releasing Hormone* ; Gonadotropins* ; Humans ; Ovarian Diseases*

No abstract available.
Contraceptives, Oral* ; Fertilization in Vitro* ; Gonadotropins*

We experienced a case of erosive adenomatosis of the nipple (EAN) in a 20-year-old lady. She have had an eczematous, erosive and crusted nipple, on the right si.de, with a serosanguineous discharge for the past two years. The biopsy specimen of eczematous lesion on the affected nipple showed focal erosion and acanthosis in the epidermis. Florid intraductal epithelial proliferation and solid nests were scattered in the nipple stroma without showing any cellular pleomorphism. The lining epithelium maintained two layers of cells the inner colurnnar cells and the outer cuboidal cells. Chronic inflammatory infiltrates of relatively dense lymphohisiocytes were found in the surrounding stromal tissue, Paget cells or underlying malignancy were not seen, and a group of tumor netst was confined to the upper part of the subareolar tissue.
Biopsy ; Epidermis ; Epithelium ; Humans ; Nipples* ; Young Adult

OBJECTIVE: To evaluate the efficacy of low dose gonadotropin releasing hormone agonist(GnRH-a) therapy combined with high dose human menopausal gonadotrpin(hMG) following estrogen & progesteron therapy for poor responders. METHODS: From May 1997 to Feb 1999, 36 patients who were defined as poor responders on previous consecutive two and more superovulation cycles were randomly allocated to lowdose GnRH-a short protocol with high dose hMG protocol pretreated with estrogen & progesterone(E/P therapy)(n=16)(study group) and the clomiphene citrate with hMG(n=20)(control group). All patients were planned to undergone in-vitro- fertilization(IVF) and embryo transfer(ET) after controlled ovarian hyperstimulation(COH). RESULTS: Two groups were similar with respect to clinical features and basal FSH and E2 levels. The mean level of E2 on day 5, 304.3+/-148.ng/ml in study group was significantly higher than that in control group, 182+/-34.9ng/ml. The mean levels of E2 on hCG day was also significantly higher in study group than control group(1324+/-320ng/ml, vs 414+/-168ng/ml). The mean day of hCG day in study group, 12.3+/-0.3 was shorter than that in control group, 13.8+/-0.4. The concellation rates of cycles were significantly lower in study group than control group(13.2% vs 84.2%). But clinical pregnancy rates did not showed the significant difference between two groups. CONCLUSION: The study suggested that a lowdose GnRH-a short protocol with high dose hMG pretreated with estrogen & progesterone can improve the ovarian response in poor responder group.
Clomiphene ; Embryonic Structures ; Estrogens ; Gonadotropin-Releasing Hormone* ; Humans ; Pregnancy Rate ; Progesterone ; Superovulation

A 45-year-old woman with epidermolysis bullosa aquisita is presented. The clinical, histological, and immunopathological features were in keeping with the previous reports of this disease. The patient also had anti-basal cell cytoplasmic antibodies at a significant titer, which is considered an unusual finding associated with this disorder. Treatment with a moderate dose of corticosteroid was effective in controlling the bullous lesions
Autoantibodies/*analysis ; Complement C3/analysis ; Cytoplasm/*immunology ; Epidermis/*immunology ; Epidermolysis Bullosa Acquisita/diagnosis/*immunology ; Female ; Humans ; Middle Aged

We experienced two cases of generalized syringoma in a 21-year and a 34-year- old healthy woman. A 34-year-old woman have had numerous yellowish to pink papules on the face, anterior chest, upper part of the back and right buttock for the past twelve years. A 21-year-old woman have had numerous yellowish to brownish papules on the face, neck and anterior chest for the past ten years, and her mother had syringoma on the eyelids. Diapnosis was confirmed by clinical and histopathological findings as generalized syringoma.
Adult ; Buttocks ; Eyelids ; Female ; Humans ; Mothers ; Neck ; Syringoma* ; Thorax ; Young Adult

The purpose of this study is to compared and analyze the shade changes(deltaE)about In-Ceram(R),IPS-Empress(R),OPC(R) by using of the spectrophotometer arising from initial status and before and after cementation of the resin cement mounted on the metal core. We used a couple of statistics such as 'One-Way ANOVA'and Multiple Range Test. We could be able to verify significantly what is being discussed here up to 95%. The results drawn from our research are as follows: 1. At the time of our experiments regarding the initial shapes of all-ceramic and mounting status of all-ceramic on the metal crown(deltaE1), and a comparison of mounting of all ceramic on the metal crown with all-ceramic cemented on the metal core(deltaE2), at the time of shade change of initial shapes and after we cemented on the metal core. (1) no significant difference among all-ceramics was found. (2) no particular difference was found regarding the In-Ceram(R) (3) a significant difference between the deltaE1 and deltaE2 regarding the IPSS-Empress(R) was found (P<0.05). (4) a significant difference between the deltaE1 and deltaE2 regarding the OPC? was found (P<0.05). 2. When we compared the shade changes (deltaE) resulted from before and after the cementation on each of the parts involved of some all-ceramic . we could be able to find shape change increase from incisal third, middle third, and cervical third in that order in In-Cream(R)(spinell), IPS Empress(R) and OPC(R) all. In addition , we could be able to find a siginificant difference between cervical third and incisal third, middle third. (P<0.05) From what we have just seen, we might conclude that there is a significant shade change difference before and after the cementation with respect to IPS-Empress(R)and OPC(R). In addition, we could also be able to find more shade change difference at the cervical third rather than incisal third and middle third depending on the parts involved.
Cementation ; Ceramics* ; Crowns* ; Resin Cements