No abstract available.
Humans ; Infant* ; Infant, Newborn* ; Radial Artery*

PURPOSE: We compared the efficacies of intravesical instillation of the mitomycin (MMC), Pasteur bacillus Carmette-Guerin (B.C.G.)(PBCG) and Tice B.C.G (TBCG) in patients with high risk superficial transitional cell carcinoma of bladder. MATERIALS AND METHODS: Our study included 49 patients with the stage T1 and the stage Ta with recurrent, grade 3, multiple or greater than 3 cm sized tumor. After complete transurethral resection of all visible tumors, 11 out of them were treated intravesically with 40 mg mitomycin C once a week for 8 consecutive weeks, 21 with 8~15 x 10(6) colony-forming units (CFU) Pasteur BCG and 17 with 2~8 x 10(8) CFU Tice BCG once a week for 6 consecutive weeks. RESULTS: The mean followup periods were 51.6 months for MMC group, 33 months for PBCG group and 17.8 months for TBCG group. The overall recurrence rates were 72.7% for MMC group, 38% for PBCG group and 17.6% for TBCG group (p=0.014). The mean times for recurrence were 8.1 months for MMC group, 9.7 months for PBCG group and 13.3 months for TBCG group (p=0.610). The tumor progression rates in each group were following, 3/11 (27%) for the MMC group, 2/21 (9.5%) for the PBCG group and 1/17 (5.9%) for the TBCG group (p>0.05). The difference in recurrence free survival rates between MMC group and PBCG group and between TBCG group and PBCG group was not significant (p>0.05). The difference in recurrence free survival rates between MMC group and TBCG group was significant (p=0.0012). CONCLUSIONS: Our result showed that TBCG group was superior to the others in recurrence rate and recurrence free survival rate, but further study including longterm followup and various HCG instillation dosage Is needed In order to confirm the preventive efficacy of BCG according to strain in superficial bladder tumor.
Administration, Intravesical ; Bacillus ; Carcinoma, Transitional Cell ; Follow-Up Studies ; Humans ; Mitomycin* ; Mycobacterium bovis* ; Recurrence ; Stem Cells ; Survival Rate ; Urinary Bladder Neoplasms* ; Urinary Bladder*

No abstract available.
Autonomic Pathways* ; Rectal Neoplasms* ; Urodynamics*

We report a case of lupus vulgaris following BCG vaccination in a 12-year-old male. The patient was vaccinated against tuberculosis on right shoulder 6 months ago. The erythemstous papular eruptions began to develop on the BCG vaccinated site 2 weeks after vaccination. The eruptions progressed to be pruritic, erythematous plaque which was flat, crescent shaped, and centrally covered by adherent scales for 6 months. Histopathological findings revealed tubercles and tuberculoid structures composed of epitheloid cells and Langhans giant, cells in the dermis. Caseation necrosis within the tubercles was slight or absent. In addition, there was an infiltrate of mononuclear cells around the tubercles. The skin lesions cleared after 6 months of treatment with oral isoniazid 300mg daily.
Child ; Dermis ; Humans ; Isoniazid ; Lupus Vulgaris* ; Male ; Mycobacterium bovis* ; Necrosis ; Shoulder ; Skin ; Tuberculosis ; Vaccination* ; Weights and Measures

Congenital Hyperextension of the Knee is a extremly rare deformity, in which the tibia is displaced anteriorly in relation to the femur. It is usually classified into three subtypes according to severity of the status: genu recurvatum, subluxation and dislocation. (Curtis and Fisher) We experienced a genu recurvatum type of congenital hyperextension of the knee in June, 1976.
Congenital Abnormalities ; Dislocations ; Femur ; Knee ; Tibia

Requirement of blood transfusion has been progressively increased and supplements by volunteer donor are not sufficient to their requirements. Moreover homologous blood transfusion are not supplied without risks, espcially the transmission of the serum hepatitis. Twenty procedures, including two total hip replacement arthroplasty, were carried out with acute hemodilutional autotransfusion. The results of this study show that autotransfusion is a safe method without difficulty of blood replacement in elective orthopedic procedures.
Arthroplasty ; Arthroplasty, Replacement, Hip ; Blood Transfusion ; Blood Transfusion, Autologous ; Clinical Study ; Hepatitis ; Humans ; Methods ; Orthopedic Procedures ; Orthopedics ; Tissue Donors ; Volunteers

Fractures involving joints and about the joints provide complex problems with small comminuted fractures, surrounding soft tissue injuries and articular cartilage damage. Various problems are also encountered on the weight bearing surface, especially on the convex side of the distal Femur. Even though many auther had recommended kinds of management upto now, operative methods are more suggested in order to get good results regarding with the accurate anatomical reduction, rigid internal fixation and early joint motion. The clinical analysis of rnanagements of 20 cases of distai femoral fracture demonstrate that seperate dual incision-bilateral or right angle plane-to originate fracture site, and anatomical reduction & rigid internal fixation, early non-weight bearing ROM exercise of joint were sometimes mandatory to treat the displaced, comminuted fracture.
Cartilage, Articular ; Femoral Fractures ; Femur ; Fractures, Comminuted ; Joints ; Soft Tissue Injuries ; Weight-Bearing

To demonstrate the stimulation effect on fracture healing by capacitively coupled electrical field, the rabbits' fibulae were fractured and treated with a capacitively coupled electrical signal (10V peak to peak, 60 kiloherz, symmetrical quadriangular wave) that was applied non-invasively over the skin surface overlying the approximate site of the fractured fibulae. Each fibula was evaluated with gross, roentgenographic, histological and mechanical tests after 21 days of the electrical stimulation, and compared to control group statistically. Maximum bending moment, Young's modulus of elasticity and bending stiffness were calculated by 3 point bending test, and the ratios of the fractured to the intact fibulae of the electrically stimulated rabbits were compared to the non-stimulated rabbits statistically. The results revealed that the fractured fibulae exposed to capacitively coupled electrical field showed the higher degree of fracture healing than the non-stimulated fibulae.
Elastic Modulus ; Elasticity ; Electric Stimulation ; Fibula ; Fracture Healing ; Rabbits ; Skin

Development of acetabulum and epiphysis of the femoral head following reduction in seventy-four patients with ninty-one congenitally dislocated hips were assessed radiologically. Acetabular index, CE angle of Wiberg, neck-shaft angle of the femur and overgrowth of the pelvis and femur were measured according to the various treatment. To evaluate results, the method of treatment was divided into four groups; closed reduction, open reduction, open reduction combined with pelvic osteotomy and modified Klisic operation (open reduction, pelvic osteotomy, femoral osteotomy and so on). Each treatment was compared with three subgroups according to ages; first subgroup was belong to patients under one year of age, second from one year to three years, third over three years. This paper agrees to Harris (1976) and Lindstrom (1979) about improvement of acetabular index and CE angle of Wiberg that showed a rapid rate of repair in the first 6 months and thereafter slowly progressed to normal range of degree. Overgrowth of pelvis and femur was also noticed in cases of hips treated pelvic and/or femoral osteotomy, moreover even in cases of open reduction only. The goal of this preliminary investigation may be supposed to propose the idea which method of treatment to the first visiting patient will approach the most satisfactory final result.
Acetabulum ; Dislocations ; Epiphyses ; Femur ; Head ; Hip ; Humans ; Methods ; Osteotomy ; Pelvis ; Reference Values

Pathologic fracture is a bresk of bony continuity within an abnormal bone. The abnormslity ma be due to systemic skeletal disease, infection, primary benign and malignant tumor, or metastati carcinoms. Among these, metastatic carcinoma to bone is most common cause of pathologic fractur excluding those due to osteoporosis. When considering the msnagement, pathologic fractures due to systemic skeletal disease usually heal with conservative treatment, while others often require operative treatment. We have experienced 20 cases of pathologic fracture in long bones for 8 years from 19 to 1987. The results were as follows ; 1. The average sge was somewhat different according to underlying diseases Malignant tumorous lesion; 53 years Benign tumorous lesion ; 17 years Chronic osteomyelitis, 42 years 2. The most common cause was malignant tumorous lesion, 8 cases(40%). 3. The most frequent site was femur, 17 cases(85%). 4. Surgical treatment was done in 17 cases(85%), and conservative treatment was done in 3 cas(1sw). 5. In 3 cases of pathologic fractures due to metaststic tumor, the pain was markedly relieved and essy nursing care was possible immediately after operation.
Clinical Study ; Femur ; Fractures, Spontaneous ; Nursing Care ; Osteomyelitis ; Osteoporosis