Langerhans cell histiocytosis refers to a group of disorders of the reticuloendothelial system which is characterized by a proliferation of histiocytes and includes eosinophilic granuloma, Letterer-Siwe diseases, and Hand-Schuller Christian disease. It may involve the femur, pelivis, scapulae, vertebrae, ribs, mandible, maxilla, skull including the temporal bone, and skin, lymph node, viscera. The severity of these diseases and their prognosis and treatments differ greatly. We have experienced a case of Langerhans cell histiocytosis in 2 year old male with bilateral temporal bone involvement. We report it with the review of literature.
Child, Preschool ; Eosinophilic Granuloma ; Femur ; Histiocytes ; Histiocytosis, Langerhans-Cell* ; Humans ; Lymph Nodes ; Male ; Mandible ; Maxilla ; Mononuclear Phagocyte System ; Prognosis ; Ribs ; Scapula ; Skin ; Skull ; Spine ; Temporal Bone* ; Viscera