1.Two Cases of Chronic Myelocytic Leukemia.
Hye Keun KIM ; Hwa Young KIM ; Young Youn CHOI ; Soon Pal SUH ; Chang Soo PARK
Journal of the Korean Pediatric Society 1983;26(2):183-187
No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
2.A Case of Congenital Ichthyosiform Erythroderma.
Myoung Joo KIM ; So Youn KIM ; Myung Hwa KIM ; Hae Young CHOI ; Ki Bum MYUNG
Annals of Dermatology 2004;16(4):197-200
No abstract available.
Ichthyosiform Erythroderma, Congenital*
3.Two Cases of Quintuplets.
Hwa Il KWAG ; Kwang Ok LEE ; Wan LEE ; Young Youn CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1989;32(5):687-694
No abstract available.
Humans
;
Quintuplets*
4.Clinical Survey of Perinatal Mortality in Multiple Pregnancy.
Hoon KOOK ; Dong Hun CHO ; Hwa Il KWANG ; Kwang Ok LEE ; Young Youn CHOI
Journal of the Korean Pediatric Society 1989;32(3):321-330
No abstract available.
Female
;
Perinatal Mortality*
;
Pregnancy
;
Pregnancy, Multiple*
5.Studies of cocktail therapy with multiple cytokines for neoplasia or infectious disease of the dog I. cDNA cloning of canine IL-3 and IL-6.
Il Seob SHIN ; Hye Ryon KIM ; Myung Jin NAM ; Hwa Young YOUN
Journal of Veterinary Science 2001;2(2):115-120
This paper describes the cloning and sequence analysis of the cDNAs encoding the canine homologues of interleukin-3 (IL-3) and interleukin-6 (IL-6). The coding sequences for canine IL-3 and IL-6 were obtained by using the reverse transcription polymerase chain reaction (RT-PCR) with RNA harvested from canine peripheral blood mononuclear cells (PBMCs). Canine IL-3 cDNA includes a single open reading frame of 432 nucleotides, which encodes a 143 amino acid polypeptide and has 44.7, 42.4, 37 and 23.7% homology with the cow, sheep, human and rat IL-3 sequences, respectively. Canine IL-6 cDNA (GenBank accession number; AF275796) encodes a putative 20-amino acid signal peptide followed by a 187-amino acid mature protein. The predicted amino acid sequence of canine IL-6 shares 60.4, 77.2, 71.0, 55.8 and 42.0% sequence identity with those of human, feline, porcine, sheep and rat IL-6, respectively.
Amino Acid Sequence
;
Animals
;
Base Sequence
;
Cloning, Molecular
;
Concanavalin A/pharmacology
;
DNA, Complementary/*chemistry
;
Dogs/blood/genetics/*immunology
;
Interleukin-3/chemistry/*genetics
;
Interleukin-6/chemistry/*genetics
;
Leukocytes, Mononuclear/chemistry/drug effects
;
Molecular Sequence Data
;
Open Reading Frames/genetics
;
Protein Sorting Signals/genetics
;
RNA/blood/genetics
;
Reverse Transcriptase Polymerase Chain Reaction/veterinary
;
Sequence Homology, Amino Acid
;
Sequence Homology, Nucleic Acid
6.Preventive Effect of Single Dose Vitamin K for the Late Hemorrhagic Disease of Infancy.
Young Youn CHOI ; Hwa Il KWAG ; Byung Hee KIM ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1990;33(5):606-614
No abstract available.
Vitamin K*
;
Vitamins*
7.Two Cases of Goitrous Hypothyroidism in Siblings.
Kwang Ok LEE ; Hwa Il KWAG ; Hoon KOOK ; Young Youn CHOI ; Tai Joo HWANG
Journal of the Korean Pediatric Society 1990;33(1):129-134
No abstract available.
Humans
;
Hypothyroidism*
;
Siblings*
8.Detection of canine distemper virus (CDV) through one step RT-PCR combined with nested PCR.
Yong Hwan KIM ; Kyu Woan CHO ; Hwa Young YOUN ; Han Sang YOO ; Hong Ryul HAN
Journal of Veterinary Science 2001;2(1):59-63
A one step reverse transcription PCR (RT-PCR) combined nested PCR was set up to increase efficiency in the diagnosis of canine distemper virus (CDV) infection after developement of nested PCR. Two PCR primer sets were designed based on the sequence of nucleocapsid gene of CDV Onderstepoort strain. One-step RT-PCR with the outer primer pair was revealed to detect 10(2) PFU/ml. The sensitivity was increased hundredfold using the one-step RT-PCR combined with the nested PCR. Specificity of the PCR was also confirmed using other related canine virus and peripheral blood mononuclear cells (PBMC) and body secretes of healthy dogs. Of the 51 blood samples from dogs clinically suspected of CD, 45 samples were revealed as positive by one-step RT-PCR combined with nested PCR. However, only 15 samples were identified as positive with a single one step RT-PCR. Therefore approximately 60% increase in the efficiency of the diagnosis was observed by the combined method. These results suggested that one step RT-PCR combined with nested PCR could be a sensitive, specific, and practical method for diagnosis of CDV infection.
Animals
;
Distemper Virus, Canine/genetics/*isolation & purification
;
Dogs
;
Polymerase Chain Reaction/*methods/*veterinary
;
RNA, Viral/genetics/isolation & purification
;
Reverse Transcriptase Polymerase Chain Reaction
;
Vaccines, Attenuated
;
Viral Vaccines
9.A case of Beckwith-Wiedemann Syndrome.
Jin Soo CHOI ; Byung Hee KIM ; Young Soo CHON ; Hwa Il KWANG ; Young Youn CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1990;33(3):367-372
No abstract available.
Beckwith-Wiedemann Syndrome*
10.Usefulness of Routine Renal Sonography Screening for Healthy Infants with Isolated Single Umbilical Artery .
Ju Mi KANG ; Eun Song SONG ; Jin Hwa KUK ; Hyung Sin LEE ; So Young KIM ; Young Youn CHO
Journal of the Korean Pediatric Society 2003;46(9):854-857
PURPOSE: It is known that single umbilical artery is frequently associated with gastrointestinal or urogenital anomaly, however, routine renal sonography has been debated in healthy neonate with isolated single umbilical artery. This study is designed to determine the usefulness of routine renal sonography in apparently healthy infants with an isolated single umbilical artery. METHODS: Thirty healthy neonates with a single umbilical artery without a major anomaly from January 1995 to July 2002 were enrolled. The authors investigated the clinical background of babies and their mothers after renal sonography after 72 hours of age. When the abnormalities were found at the first renal sonography, the severity of hydronephrosis and degree of obstruction and renal function were analyzed by follow up renal sonography, voiding cystourethrography(VCUG) and technetium-99m-dimercaptosuccinic acid(DMSA) scan or technetium-99m-mercaptoacetyl-triglycerine (MAG3) scan. RESULTS: Among the 30 healthy patients with isolated single umbilical artery, five patients(16.7%) showed abnormalities on first renal sonography with one major(3.3%) and four(13.4%) minor renal anomaly(minimal or mild hydroneohrosis). One major renal anomaly(severe hydronephrosis) showed severe decreased renal function on MAG3 scan without reflux, and the other four minor regressed spontaneously on follow up study. CONCLUSION: The value of routine early renal sonograpy for detecting renal anomaly in healthy infants with an isolated single umbilical artery remained unclear because most of the anomalies would regress spontaneously in the follow up study.
Follow-Up Studies
;
Humans
;
Hydronephrosis
;
Infant*
;
Infant, Newborn
;
Mass Screening*
;
Mothers
;
Single Umbilical Artery*