Since Methoxyflurane, as a new potent, non-explosive, volatileanesthetic agent, was first studied by Van Poznak and Artusio in 1960, was administered to one hundred surgical patients. The following are the results of clinical observation. 1) Methoxyflurane is easily administered with a relatively simple vaporizer such as Heidbrink No.8 ether vaporizer in semi-closed system. 2) Anesthetic concentration is easily controlled with experience so that deep anesthesia can be avoided. 3) Excellent muscle relaxation is produced at intermediate levels of anesthesia without producing apnea. 4) Methoxyflurane is not irrttant to respiratory tract, not producing respiratory secretion. So that achoice of agent in respiratory disease. 5) Analgesia extends into the recovery phase, minimizing the need for narcotics in the immediate postopoerative period. 6) Induction and recovery from anesthesia is relatively prolonged. However, nausea, vomiting or delirium is less frequent than after ether anesthesia.
Analgesia ; Anesthesia ; Apnea ; Delirium ; Ether ; Humans ; Methoxyflurane* ; Muscle Relaxation ; Narcotics ; Nausea ; Nebulizers and Vaporizers ; Respiratory System ; Vomiting

The patient was scheduled for subtotal gastrectomy and was premedicated with morphine 10 mg and atropine 0.4 mg. For induction of anesthesia 200mg of thiopental were injected intravenously. A number 34 French cuffed endotracheal tube was passed into the trachea under direct vision following I.V.S.C.C. 60 mg. Anesthesia was maintained with ether oxygen without difficulty. Approximately one hour and thirty minutes following induction of anesthesia there was a complete airway obstruction due to overinflation of endotracheal cuff. The following precautions should be considered; Prompt recognition or cause, prevention and treatment of airway obstruction. 2. A thorough examination of endotracheal tubes before use. 3. The use of endotracheal intubation never guarentees a patent airway. 4. A suction catheter passed through the endotracheal tube just after intubaon is valuable methode for the recognition of air way obstruction.
Airway Obstruction ; Anesthesia ; Atropine ; Catheters ; Ether ; Gastrectomy ; Humans ; Intubation, Intratracheal ; Morphine ; Oxygen ; Suction ; Thiopental ; Trachea