1.Identification of progressive cervical epithelial cell abnormalities using DNA-image-cytometry
Journal of Medical Research 2005;33(1):16-23
Cohort prospective study was carried out on 196 women with Papanicolaou (Pap) smears diagnosed as ASC, LSIL or AGC. Results: reference standard verification was available in 108 patients. The rate of DNA-aneuploidy in Pap smears increased significantly from cervical intraepithelial neoplasia (CIN) 1 (54%) and CIN2 (64.3%) to CIN3 or above (83.3%) in subsequent biopsies (p<0.05). Using ASC/LSIL/AGC as input cytological criteria and CIN2 or above as output histological diagnosis, positive predictive value (PPV) of conventional cytology and DNA-ICM was 35.2% and 65.9%, respectively (p<0.01). Negative predictive value (NPV) of DNA-ICM was 85.0%. Using CIN3 or above as output histological diagnosis, conventional cytology showed a PPV of 22.2%. PPV and NPV of DNA-ICM were 43.9% and 93.3%, respectively.
Uterine Cervical Diseases
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Diagnosis
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DNA
2.Polycystic ovarian syndrome- metabolic aspects
Journal of Medical Research 2005;37(4):77-80
Polycystic ovarian syndrome (PCOS) was not considered as a simple disease at ovary but as a metabolic syndrome. The centre of this process is the disturbance of gonadotropin and metabolism of insulin/insulin-like growth factor 1 (IGF1). Some main symptoms: mentruation disorder, hyperandrogenaemia, obesity and hyperresistant to peripheral insulin with hyperinsulinaemia. For those patients have symptoms on skin, the local treatment is provided, other systemic treatments were used for those have metabolic diseases. Women with polycystic ovarian syndrome often are obesity. Metformin lose weight, regulate menstruation circle and increase significantly ovulation. Reducing androgen concentration can improve the symptom of acne and hypertrichosis. Infertile treatment, metformin can be effect in stimulating ovaries by clomiphen or FSH, increase the rate of having pregancy and reduce the rate of miscarriage in women with PCOS.
Polycystic Ovary Syndrome, Basal Metabolism
3.In-treatment needs of populations of Bac Giang town
Journal of Practical Medicine 2004;474(3):71-73
The study surveyed the morbidity and hospital admission of Bac Giang city population in the year 2001, especially the prevalence of cancer. 3.000 households were enrolled in the study. Data were collected and interviews were conducted. Analysis showed people had a high demand of health care in hospital, especially with cancer management. 31.1% of urban population demanded a hospital admission. In 5 year period in the city, the cancer incidence was 158.9/100.000 people in average. The highest was in 50-69 age group, and this incidence was higher in male than female
Therapeutics
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Inpatients/morbidity
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Morbidity
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Epidemiology
4.Nutritional status, morbidity and weight increase level of pregnant women in VinhBao district, HaiPhong city the year 2001
Journal of Practical Medicine 2004;481(6):78-80
In Vinh Bao district, Hai Phong city in the year 2001, 825 female subjects aged 18-35 years old with first pregnancy or one child, without abortion or immature delivery, were divided into 2 groups according to BMI (For CED group: BMI < 18.5 and normal group: BMI 18.5). The prevalence of chronical energy deficit (CED) before pregnancy was 29%, among them, 1st grade CED 21.2%, 2nd grade 6.3%, 3rd grade 1.5%. The prevalence of common diseases (cough, fever, headache, diarrhoea…) in CED - 40.2%, higher than normal group - 26.3%. In general, for both two groups, morbidity reduced progressively in the course of pregnancy: the prevalence was 18.6% in the first trimestre, 8.8% in the second trimestre and 8.4% in the terminal 3rd trimestre. Considering body weight, in the first trimestre the weight gained by 0.48kg (CED group: 1.19lg, normal group 0.19kg), in 2nd trimestre, the weight gained 2.46kg (CED group 2.91kg, normal group 2.28kg), in the last 3rd trimestre 4.08kg (CED group 4.28kg, normal group 4.0kg).
Nutritional Status
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Morbidity
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Body Weight
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Pregnant Women
5.The situation of workers'health at Ha Bac nitrate and chemical factory
Journal of Practical Medicine 2004;483(7):77-78
The average incidence/case/year of Ha Bac nitrate and chemical factory during two years (2002-2003) was 1.38 incidence/case/year (2002) and 1.63 incidence/case/year (2003). The diseases were high incidence as follows: odonto-maxial-facial disease, ear-nose-throat disease. Workers with I health level and II health level were the highest: 70.33% (2002) and 65.05% (2003). The rate of workers with III health level were very high and tend to increase, remained the rate of workers with V health level.
Health
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Nitrates
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Chemical Industry
6.Some risks of factors of mother effect to weight and height of newborn children at Vinh Bao district - Hai Phong city in 2001
Journal of Practical Medicine 2004;483(7):78-80
Weight in average was 2911.4g (group of mothers with CED): 2905.6g; group of mothers without CED: 2913.8g, (boys: 2961g; girl: 2856g). Low birth weight rate was 11.6% (CED: 9.6%; normal: 12.4%); (boys: 10.4%; girls: 12.8%). Length of newborn babies in average was 48.3 cm (CED: 48.2 cm; normal: 48.4 cm), (boys: 48.6 cm; girls: 48 cm). Only 2.1% of newborn babies had length at birth lower 45 cm, nearly 98% had length at birth 45cm. Height of mother < 150 cm before pregnancy was high ralative risk to weight and length at birth of newborn babies.
Risk Factors
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Mothers
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Child
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Infant, Newborn
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Body Weight
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Body Height
7.A study on the contents of steroid hormones and micro-substances in some salt-water fishes in Vietnam
Journal of Medical and Pharmaceutical Information 2004;0(2):35-38
In this study, the contents of steroid hormones and micro-substances in 5 salt-water fishes including Sea-horse, White hering, Garrupa, Selachian and Mackerel were studied. The result demonstrated that: the contents of steroid hormones in 5 mentioned fishes were relatively higher than other salt-water creatures. The study also explored the availability as well as contents of some necessary micro-substances in these salt-water fishes (K, Ca, Cu, Fe, Zn, Mn, Se). Although, the ability of using the active elements in the 5 salt-water fishes as medicines to enhance health and prevent diseases is very potential, it needs further studies
Steroids, Hormones, Fishes
8.Investigation and evaluation of the task to manage the safe rational and effective use of antibiotics in the Central Hospital of Gynecology and Obstetrics
Pharmaceutical Journal 2004;44(2):36-38
To survey and assest the safe rational and effective use of antibiotics. The success and shortage in the use of C in the National hospital of Gynecology and Obstetrics. The management of antibiotic use in functional department of the hospital was subjected to a retrospective study using an interviewed questionary, comparative and analyzed investigation. Results showed some success in the safe, rational and effective use of antibiotics contributing significantly in improving efficiency and the cost :In addition, this helped to minish the antibiotic resistancy
Anti-Bacterial Agents
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Epidemiology
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Drug Resistance, Microbial
9.Nutrition situation, morbidity and weight gain of pregnancies at Vinh Bao district, Hai Phong city in 2001
Journal of Practical Medicine 2005;0(12):29-32
Study on 825 pregnant women at Vinh Bao district – Hai Phong city in 2001 showed that: the practice of reproductive health of two groups of mothers ( Chronic Energy Deficiency (CDE) and nomal) was relatively good. Lack of nutrition status and anthropemetric indicators, especially height of mother were improved. The rate of CDE of woman before pregnancy was 29% (CDE: degree I: 21.2%; CDE degree II: 6,3%; CDE degree III: 1.5%). Weight in average: 44.96kg, height in avarage: 153.2cm. Weight gain were improved, weight in CDE group was higher than nomal group but lower than recommendation.
Nutritional Status
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Nutrition Surveys
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Pregnancy
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Weight Gain
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Morbidity
10.Water quality and the health of community
Journal of Medical and Pharmaceutical Information 2004;0(8):7-8
The quality of drinking and running water had major influenced to human health. The use of comtanimated water could be cause of cholera, dysenteria, and typhoid outbreaks with different scales. Aside from many water-born diseases with the causes of microbilogy, chemical contamination also is a major threat for community health. So, it is necessary to strengthen control the quality of water by authorities and community
Water
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Health
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Health Services
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Residence Characteristics