1.A Rare Congenital Anomaly: Interrupted Aortic Arch and Giant Ascending Aortic Aneurysm in a Young Male.
Muhammed Hakan TAS ; Ziya SIMSEK ; Husnu DEGIRMENCI ; Hayri OGUL ; Ugur AKSU ; Abdulmecit KANTARCI
Korean Circulation Journal 2013;43(8):578-579
No abstract available.
Aorta, Thoracic
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Aortic Aneurysm
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Humans
;
Male
2.Left Atrial Thrombus in a Patient with Mitral Bioprosthetic Valve.
Muhammed Hakan TAS ; Ziya SIMSEK ; Husnu DEGIRMENCI ; Hayri OGUL ; Abdurrahim COLAK ; Huseyin SENOCAK
Korean Circulation Journal 2013;43(6):432-433
No abstract available.
Humans
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Thrombosis
3.The Impact of Trimetazidine Treatment on Left Ventricular Functions and Plasma Brain Natriuretic Peptide Levels in Patients with Non-ST Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
Selami DEMIRELLI ; Sule KARAKELLEOGLU ; Fuat GUNDOGDU ; Muhammed Hakan TAS ; Ahmet KAYA ; Hakan DUMAN ; Husnu DEGIRMENCI ; Hikmet HAMUR ; Ziya SIMSEK
Korean Circulation Journal 2013;43(7):462-467
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate the impact of treatment with oral trimetazidine (TMZ) applied before and after percutaneous coronary interventions (PCI) on short-term left ventricular functions and plasma brain natriuretic peptide (BNP) levels in patients with non-ST segment elevation myocardial infarction (NSTEMI) undergoing PCI. SUBJECTS AND METHODS: The study included 45 patients who were undergoing PCI with the diagnosis of NSTEMI. The patients were randomized into two groups. The first group (n=22) of the patients hospitalized with the diagnosis of NSTEMI was given conventional therapy plus 60 mg TMZ just prior to PCI. Treatment with TMZ was continued for one month after the procedure. TMZ treatment was not given to the second group (n=23). Echocardiography images were recorded and plasma BNP levels were measured just prior to the PCI and on the 1st and 30th days after PCI. RESULTS: The myocardial performance index (MPI) was greater in the second group (p=0.02). In the comparison of BNP levels, they significantly decreased in both of the groups during the 30-day follow-up period (29.0+/-8 and 50.6+/-33, p<0.01 respectively). However, decreasing of BNP levels was higher in the group administered with TMZ. The decrease of left ventriclular end-diastolic volume was observed in all groups at 30 days after intervention, but was higher in the group administered with TMZ (p=0.01). CONCLUSION: Trimetazidine treatment commencing prior to PCI and continued after PCI in patients with NSTEMI provides improvements in MPI, left ventricular end diastolic volume and a decrease in BNP levels.
Brain
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Echocardiography
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Follow-Up Studies
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Humans
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Myocardial Infarction
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Natriuretic Peptide, Brain
;
Percutaneous Coronary Intervention
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Plasma
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Stroke Volume
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Trimetazidine
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Ventricular Function, Left