2.280 people living in DongDa district, Hanoi city were randomly selected and interviewed concerning the health status, the physical illness the emotional troubles as well as the habit of use of alcohol, sleeping medication, pain medication, and their suicidal thought in whole life. The results showed that there is an association between the suicidal thoughts and cancer, asthma. Anxiety, depression and fear were considered predictors for these thoughts, the habit for using sleeping and pain relief medications were associated statistic significantly with the suicidal thoughts but there was not an association with the use of alcohol.
Population ; Suicide ; Sick Role

Fluorescence in Situ Hybridization (FISH) is cytogenetics - molecular technique. FISH is the rapid detection technique of chromosomal aberration by chromosome specific probes applied to interphase cells. In this study, the authors used Kit duple DNA probe for chromosome 13, 21, X, Y to prenatal diagnosis of Down’s syndrome. With 6 amniotic fluid samples, the authors obtained the results as follows: 2 samples were Down’s syndrome trisomy; 1 sample was Patau syndrome trisomy; 3 samples were normal; 1 sample male foetus died without clear causes. Cytogenetic result: 46, XX but FISH result: 46, XY; PCR (Polymerase Chain Reaction) result: TDF (Testis Determining Factor): (+). These results were confirmed by chrosome analysis.
Down Syndrome ; Prenatal Diagnosis

In 1997 (1/1997-10/1997) with lymphocytes culture technique, technique for preparing chromosome slides, and Barr body technique (giemsa + trypsin). We determined Karyotyp for 60 patients with suspected genetic disorders. The result showed determined sex for 40 patients (Karyotyp 46,XX or 46,XY). 2 interrex with Karyotyp 46,XX/46,XY. 2 intersex with Karyotyp 46,XX. Determining Karyotyp for 8 patients with suspected Turner Syndrome. One of them: 45,X/46, X, r(X). Determining Karyotyp for 2 patients with suspected Down Syndrome. (1 case: 46,XX; another: 47,XX, +21). Determining Karyotyp for another patients: suspected: panconi; 47,XYY; Sterility..
Genetics ; Chromosome Aberrations

143 lecturers and 1360 students in basic, biomedical, clinical and community departments of Ha Noi Medical University were interviewed on the current situation of training methods. The results showed that 38.4% teachers applied active training methods and there is a dramatic change in comparison to prior 1995 in biomedical group (p<0.05), more than 70% lecturers had syllabus, gave questionnaires and assessment after lesson. 60% lecturers reported that traditional training methods made students become negative while active method made students more active. 54.2% of students read references that related to clinical subjects. 96.5% of students read the bulletin of basic medical departments. 61.2% students like the active methods in training
education ; Methods

In total, 511 Vietnamese patients (515 commit suicide events) admitted during the period from January 1, 1999 to April 30, 2001 were included in the study. The results shown that: nearly a half (48.7%) of the patients was in the age group of 15-24 years old. The female to male ratio of the patients living in the urban area (2.1:1) is higher than that in the rural area (1.2:1) with p<0.01. Among the patients: farmers (19.8%), students (24.7%) and homework (20.8%). Commit suicides were made more frequently in April with a significant difference between the urban and rural area (p=0.02). Conflicts with partners and other family members were the main causes of commit suicide. Anticarcotic and antipyretic were often used among the patients living in the urban, while pesticide and raticide more commonly in the rural areas as a means of commit suicide.
Suicide ; Poison Control Centers

An one year old girl with congenital torticolis was subjected to study. At birth, an oval neck mass was persisted at the right side, which made the head tilted. The patient was treated by massage to reduce the contraction of clavicle muscle. Infra-red was irradiated during 10 minutes in the neck and the left side lumbar regions. Exercises were practised to rotate the neck and the trunk, and to stretch the neck. Mother was trained for holding and carrying the child at home. 4 months of treatment gave good results
Torticollis ; Therapeutics ; Physical Therapy (Specialty)

Background: Down syndrome is a developmental disorder caused by an extra copy of chromosome 21, is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. It affects about 1 in every 700 babies. The fetus having high risk for Down syndrome (OS) can be detected early by ultrasound. Objectives: The aim of the study is to find out some ultrasound markers that relate to OS fetus. Subjects and method: A descriptive study was carried out on 612 pregnant women with fetus \ufffd?12 weeks by ultrasound to detect abnormal markers in fetus. The fetus were diagnosed Down syndrome by analysis chromosome from amniocyte and monitor up to the neonate. Then, finding out association between OS fetus and ultrasound markers. Results: Among 612 pregnant women,36/12 pregnant women had abnormal imaging in fetus, 11/12 pregnant women had OS fetus. There were 12 pregnant women detected OS fetus. 6/12 OS fetus associated with the maker of nuchal skin fold (cut off 2: 3mm at the first trimester and 2: 6 mm at the second trimester): Detection rate (DR) was 50%; false positive rate (FOR): 0,83%. 3/12 OS fetus associated with the marker of duodenal atresia. DR was 25%; FOR: 0%. Conclusions: The two common markers associated with OS fetus: \r\n', u'the first marker was nuchal skin fold (with cut off 2: 3mm at the first trimester and > 6 mm at the second trimester) and the second marker was duodenal atresia. \r\n', u' \r\n', u'
Down Syndrome ; Fetus/ anatomy & ; histology ; abnormalities ; physiopathology ; ultrasonography

Background: Mental retardation is a common pathological state in children, accounting for about 1 - 3%. Children with mental retardation should have a life of integrity and proper support. The discovery and assessment the children will help us to orient the education, assistance and early intervention for them at each location. Objectives: This study aimed at determining the prevalence of mental retardation (MR) among children in some quarters and communes of Hue city and the degrees of mental retardation in these children. Subjects and method: Screening by WHO questionnaire \u201cTen Question screen for disability\ufffd?and learning results (if possible) of children from 6 to under 16 years old in 5 quarters (urban) and 2 communes (rural) randomly selected in Hue. Diagnostics and evaluations are based on the criteria of ICD \ufffd?10. Results: The prevalence of MR in this study was 0.94% (95%CI = 0.82 \ufffd?1.07), 1.18% in rural area and 0.84% in urban area; 1.16% among boys and 0.70% among girls. Mild MR accounts for 62.67% moderate: 19.36%, severe: 11.52% and profound: 6.45%. Conclusion: The prevalence was statistically significant higher in rural area than in urban area and in boys than in girls. There were predominant percentages of severe and profound MR.
Mental Retardation/ epidemiology ; Prevalence ; Children ;

Background: The fetus having risk for Down sydrome (DS) can be detected early by AFP, \u03b2hCG in maternal serum to detect the fetus having risk of Down sydrome. Objectives: Determining values of AFP, \u03b2hCG in maternal serum to detect the fetus having risk of DS. Subjects and method: Determining the concentration of AFP, \u03b2hCG in maternal serum of 591 pregnant with fetus \ufffd?12 weeks to detect the fetus having DS screening risk. The fetus are diagnosed DS by analysing chromosome from amniocyte and monitor up to the neonate. Then, finding out association between DS fetus and AFP, \u03b2hCG in maternal serum. Results: 75/591 of subjects screened were screen positive, 6/7 DS fetus associated withscreen positive, (cut off AFP \ufffd?0,75 MoM, \u03b2hCG \ufffd?2,2 MoM). Detection rate (DR) was 85,71%; false positive rate (FDR): 11,81%. Only base on AFP: DR was 71,43%; FDR: 11,81%. Only base on \u03b2hCG DR was 28,57%; FDR: 0,51%. Conclusion: DR base on AFP is higher than base on \u03b2hCG. If combining AFP and \u03b2hCG, DR is the highest. AFP is important role in screening DS fetus.
Down Syndrome/ diagnosis ; Predictive Value of Tests ; Prenatal Diagnosis ; Pregnancy ;

Background: Fragile X Syndrome (FXS) is the second cause of Mental Retardation (MR) and the first cause of familiar MR. This syndrome affects up to 1/4000 men and 1/8000 women. X syndrome is often diagnosed by molecular biology technique such as RCR and Southern blot. Until now there is no study on FXS in Vietnam. Objectives: This study is aimed at: (1) Determine FXS among children with MR by technique of molecular biology. (2) Determine the mutation of FMR1 gen in families having children with FXS. Subject and Method: 214 children between 6 and 16 years of age (136 male and 78 female) with MR were analyzed FMR1 gen by PCR and Southern blot techniques. Families of children with FXS were also analyzed. Result and conclusion: This is the first study on FXS using the techniques of molecular biology in Vietnam. Identified 3 children with FXS, accounting for 1.4% of MR. Children with FXS and members with full mutation and premutation were found.
Fragile X syndrome ; FMR1 gene ; Mental retardation