1.Study on the effective control of postpreal blood glucose of resistant starch cakes in patients with type 2 diabetes
Huu Dung TRAN ; Quang Hung LE ; Bao Dung VO ; Hoang Vu NGUYEN ; Thanh Bao Yen LUONG ; That Hy TON ; Phuoc Hieu DOAN ; Thi Bich Hien PHAM ; Huu Tien NGUYEN ; Hai Thuy NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):52-58
Background: This study was conducted on 93 volunteers with type 2 diabetes to investigate the ability of acetylated wheat starch cake containing 32.1% resistant starch to control postprandial blood glucose levels. Material and methods: The study was designed using a crossover, double-blind trial method. During each testing day, after a minimum of 12 hours of overnight fasting, each participant consumed two identical cakes containing either 80 g of acetylated wheat starch or 80 g natural wheat starch with 330ml of water within 15 minutes. Blood glucose levels were measured at baseline, 60 mins (G1), and 120 mins (G2) after ingestion. The predictive value of factors that contribute to the ability of resistant starch to control postprandial blood glucose was determined by the area under the receiver operating characteristic (ROC) curve based on the combined effect of the cake weight-to-BMI ratio (g/m²BMI) and HbA1c. Results: 60 mins and 120 mins postprandial capillary glucose levels after consuming acetylated wheat starch cake (10.4 ± 1.2 và 9.2 ± 1.2 mmol/L, respectively) were significantly lower compared with natural wheat starch cake (13.3 ± 1.8 và 11.2 ± 1.8 mmol/L, respectively) (p < 0.05). For good control of postprandial blood glucose levels, a maximum of 80 g of acetylated wheat starch can be used per serving for patients with type 2 diabetes with HbA1c ≤ 7.25 without blood glucose-lowering medication is required. Conclusion: acetylated wheat starch has better ontroled of postprandial blood glucose compared with natural wheat starch in patients with type 2 diabetes. This is very suitable in the processing of diets including resistant starch for patients with type 2 diabetes for the purpose of both supporting treatment and improving quality of life.
2.Knowledge, attitude and practice on the use of vietnamese medicinal plants for common diseases treatment among people in Phu Vang district, Thua Thien Hue province
Van Hung NGUYEN ; Thi Cam Quy TRUONG ; Xuan Vu NGUYEN ; Duc Hieu NGUYEN ; Thi Vui HUYNH ; Thi Ha Nhi TANG ; Thi Ngoc Giao LE ; Thanh Tu TRUONG ; Dinh Tuyen HOANG ; Dinh Hue LE
Hue Journal of Medicine and Pharmacy 2023;13(7):75-82
Background: Vietnamese herbs are considered as a botanical resource, a precious medicinal source of our country, and are widely used in the residential community in general. Phu Vang district is a coastal plain and lagoon in Thua Thien Hue province, where people’s living standards are not high, health facilities lack equipment. Therefore, the needs for primary health care are necessary to be strengthened, especially in the treatment of common diseases using Vietnamese herbs to reduce costs and improve health for the people. However, the knowledge of the local residents about Vietnamese herbs preventing and treating common diseases at home has not been surveyed. Objectives: (1) To describe the knowledge, attitude and practice on the use of Vietnamese herbs used in the treatment of common diseases of residents in some communes of Phu Vang district. (2) To determine some factors related to the use of Vietnamese herbs in the treatment of common diseases among the residents. Methods: A cross-sectional study was conducted on 400 residents representing the heads of households in three communes of Phu Vang district, Thua Thien Hue province, Thua Thien Hue province. Descriptive statistical analysis and multivariable logistic regression were performed with SPSS software. Results: Knowledge: Good: 45.2%; Fair: 30.8%; Average: 9.0%; Poor: 2.0%. Attitude: 97.0% of residents preferred using Vietnamese herbs in the treatment of common diseases, and 96.6% of residents agreed to continue using Vietnamese herbs to treat similar diseases later. Practice: Good: 7.8%; Fair: 16.7%; Average: 25.3%; Poor: 50.2%. Receiving information about Vietnamese herbs and growing them at home gardens were two factors related to the use of Vietnamese herbs to treat common diseases (p < 0.05). Conclusion: The practice of using Vietnamese herbs to treat common diseases of the residents in Phu Vang district is still low, it is necessary to strengthen educational propaganda to raise the awareness and practice among residents on the prevention and treatment of diseases with Vietnamese herbs at home.
3.Trichoderma asperellum Chi42 Genes Encode Chitinase.
Nguyen Hoang LOC ; Hoang Tan QUANG ; Nguyen Bao HUNG ; Nguyen Duc HUY ; Truong Thi Bich PHUONG ; Tran Thi Thu HA
Mycobiology 2011;39(3):182-186
Four Trichoderma strains (CH2, SH16, PQ34, and TN42) were isolated from soil samples collected from Quang Tri and Thua Thien Hue provinces in Vietnam. The strains exhibited high chitinolytic secretion. Strain PQ34 formed the largest zone of chitinase-mediated clearance (> 4 cm in diameter) in agar containing 1% (w/v) colloidal chitin. Analysis of the internal transcribed spacer regions of these strains indicated that they were Trichoderma asperellum. The molecular weights of the chitinases were approximately 42 kDa. Chitinase genes (chi42) of T. asperellum strains TN42, CH2, SH16, and PQ34 were 98~99% homologous to the ech42 gene of T. harzianum CB-Pin-01 (accession No. DQ166036). The deduced amino acid sequences of both T. asperellum strains SH16 and TN42 shared 100% similarity.
Agar
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Amino Acid Sequence
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Chitin
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Chitinase
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Colloids
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Molecular Weight
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Soil
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Sprains and Strains
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Trichoderma
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Vietnam
4.Sagittal relationship index on cephalometric film of Vietnamese citizens aged 18 to 19 years
Loan Thi Thu Do ; Hung Dinh Mai
Journal of Medical Research 2008;54(2):78-81
Background: There are many factors to assess face morphology and standard occlusion, in which sagittal relationship index is an important one. This index in cephalometric film can help to study developmental changes, to evaluate structures of bone and soft tissues, and to make decisions in orthodontic treatments. Objectives: Determination of the sagittal relationship index on cephalometric film in Vietnamese citizens aged 18 to 19 years. Subjects: 100 Vietnamese (42 men and 58 women) aged 18 to 19 years, who had 28 healthy and natural teeth. Method: Descriptive cross-sectional study. All participants were X-rayed on cephalometric film and then special points, angles, and planes were defined on these films. Data was analyzed by using one-way ANOVA test, t - Student test in Epi-Info software version 6.04 and SPSS version 10.0. Results and conclusion: Some sagittal craniofacial indexes on cephalometric film were defined as followed: in both sexes, mean SNA (degree) = 81.99 +/- 3.77 (82.81+/-4.40 in men, 81.40+/-3.16 in women, p> 0.05); mean SNB = 79.66 +/- 4.10 (82.81+/-4.36 in men, 78.40+/-3.40 in women, p< 0.05); mean ANB = 2.33 (1.40 in men, 3.00 in women, p< 0.05); mean l/SN = 109.36 +/- 6.46 (110.55+/-7.77 in men, 108.49+/-5.22 in women, p> 0.05); mean 1/ MP = 95.85 +/- 6.86(93.68+/-7.27 in men, 108.49+/-6.15 in women, p> 0.05); mean 1/1 = 120.02 +/- 13.06 (125.42+/-9.08 in men, 116.10+/-14.13 in women, p< 0.05). These findings showed that the Vietnamese populaces have alveolar protrusive tendency.
Sagittal relationship index
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cephalometric film
5.Application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains
Ly Minh Ho ; Hoa Thanh Tran ; Lien Kim Pham ; Hung Van Nguyen ; Phuong Thi Hoang ; Sy Ngoc Dinh
Journal of Preventive Medicine 2008;0(3):60-66
Background: Recently, microplate almar blue assay has been used commonly in detecting gen related to tuberculosis drug resistance, which provides results after 5-7 days with lower cost compared to traditional methods. Objective: To evaluate the application of microplate almar blue assay for rapid detection of drug resistance of M. tuberculosis strains. Subject and Method: A microplate-based assay which uses Alamar blue reagent - an oxidation reduction dye (MABA), was used for the determination of the anti-tuberculosis drug (isoniazid-INH, rifampicine-RIF, streptomycine-STR and ethabuton=EMB) resistance of 96 M. tuberculosis strains isolated from Vietnamese patients in comparison to those obtained by conversional method. Result: MABA showed to have high sensitivity and specificity in testing the sensitivity to individual anti-tuberculosis drugs (from 82.4% for STR to 93.3% for - INH and from 82.5% for EMB to 98.4% for STR; respectively), as well as for the multi-drug resistant M.tuberculosis (86.4% of sensitivity), highly correlated with the result determined by proportion method. Conclusion: MABA reveals the advantage in shortening test time, in simple performance and lower cost compared with the conversional culture based methods.
Microplate almar blue assay
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M. tuberculosis
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drug resistance
6.Assessing the emergency situation for peripheral vascular wounds/trauma in Viet Duc Hospital from 2004 to 2006
Uoc Huu Nguyen ; Nghia Dinh Che ; Hung Duc Duong ; Hung Quoc Doan ; Huu Cong Nguyen ; Lu Huu Pham ; Tien Anh Do ; Thanh Ngoc Le
Journal of Surgery 2007;4(57):12-19
Background: peripheral vascular wounds/trauma is a severe type of surgical emergency, the increasing rate due to the rapid increase of traffic, labor and living accidents. Subjectives and Method: retrospective study, all patients with peripheral vascular wounds/traumas (alone or combination in multiple trauma) were emergency operated at Viet Duc Hospital from January 2004 to June 2006. Results: A total of 310 patients with peripheral vascular injuries in the study, of which accounted for 62.3% of injury, trauma group accounted for 37.7%. The mean age of 30. In first aid, pressed tape accounted for high rate (71.5%). Rate of popliteal vascular trauma due to fractures around the knee accounted for 65.5%, the rate of brachial vascular trauma with fractures around the elbow was 50%. Rate of late diagnosis of arterial trauma was 14.6%, higher than the arterial wounds (2.6%). The rate of ultrasound for forelimbs - where vessels were many wounds, was lower than that for hindlimbs - where vessels were many traumas (44% vs 67.9%). For vascular wounds, more directly vascular connection and more intervention on veins, whereas, for arterial trauma, more vascular graft. Rate of complications was low (7.4%), with no deaths. Conclusions: Overall, the results of emergency surgery for peripheral vascular wounds/trauma were well. No cases was death from vascular lesions, rate of complications was low.
Blood Vessels/ injuries
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Emergencies
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7.Assessing respiratory tract infections on patients with tracheostomy due to head trauma in Viet Duc Hospital
Hung Dinh Kieu ; Duc Minh Duong
Journal of Surgery 2007;4(57):30-34
Background: in head trauma, increased intracranial pressure and cerebral edema are the main factors causing death. One of the most effectiveness anti-cerebral edema measures is to ensure ventilation, mechanical ventilation is best. But in practical conditions of Vietnam, with a very large number of patients, number of ventilator is insufficient for patients, so tracheostomy is a relatively simple method but has saved the lives of many patients. Objectives: to assess the situation of respiratory tract infections in patients with tracheostomy due to head trauma; to study the common bacterial species and antibiotic response in the treatment of these infections. Subjectives and Method: a prospective descriptive study on all patients with head trauma had been tracheostomy, treated and monitored at department of neurosurgery, Viet Duc Hospital from November 25, 2005 to April 25 in 2006. Results: 80% of patients infected with multiple bacteria. The rate of respiratory infection after 3 days of tracheostomy was 90%. The common bacterial species were gram (-) (82.58%), highest P.aeruginosa (34.04%), followed by other intestinal Gram (-). The species of Gram (+) only accounted for 17.02%, including staphylococcus (6.38%). Results of Antibiotics Sensitivity Test showed that 2nd regimen (Augmentin + aerosol including: ampicinllin and Nebule) was effective treatment. Conclussions: the ability of bacterial infecting to respiratory tract was very soon. The rate of respiratory infection after 3 days of tracheostomy was very high. The common bacterial species were gram (-). Antibiotic combination was high effective regimen.
Respiratory Tract Infections
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Craniocerebral Trauma
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Tracheostomy
;
8.The situation of HIV/AIDS infection of prisoners at Binh Dien prison from 2005-2006
Tam Le Nguyen ; Minh Quang Duong ; Hue Thanh Dinh ; Son Dinh Nguyen ; Ngoc Thi Tran ; Hoa Thai Nguyen ; Son Van Ly ; Son Huu Le ; Dung Thi My Tran ; Hung Chi Nguyen
Journal of Preventive Medicine 2007;17(4):45-50
Background: With the development of HIV/AIDS pandemic in community, amount of HIV/AIDS people more and more increase in prison. Objectives: Determine the rate of HIV/AIDS infection of prisoners at Binh Dien prison. Learning about related elements to HIV/AIDS infection. Subjects and method: Prisoners at Binh Dien prison. Method: 492 prisoners were chosen, interviewed directly and taken blood samples to HIV test. Using cross-sectional study on accidental samples. Techniques were used in this study: SERODIA-HIV and ELISA technique. Results: The rate of current HIV/AIDS infections was 21,74%, some HIV/AIDS related factors in the prison included sex, religion, income source, marrital status, common knowledge of HIV/AIDS, drug addiction history, needle sharing, sexually transmitted disease history, body tatoos and forskin inserted with metal balls, alcohol and beer drinking history, some factors such as: age and educational level were not associated with HIV/AIDS infection in prison. Conclusion: Strengthen interventional activities in prison to prevent HIV/AIDS spread between prisoners. To prisoners who were not infected HIV/AIDS: strengthen educational communication to they may prevent themselves from HIV/AIDS infection behaviors. To HIV/AIDS prisoners: Need to educate and consult especially to they have right behaviors, prevent HIV/AIDS spread for the others while they were in prison as well as they return to society.
HIV Infections/ blood
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complications
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epidemiology
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9.Skull defect cranioplasty after operation of traumatic brain injury with carbon composite "intost-2"
Journal of Practical Medicine 2005;517(8):57-60
Cranioplasty was proposed by Falloppio and later by Pare in 1634. During the last century, in particular, there has been a marked increase in the use of alloplastic materials for cranioplasty comprising a wide variety of materials: tantalium, titanium, acrylic, polyethylene, silicone and ceramics. The authors assess the efficacy of cranioplasty with carbon composite” intost-2” for cranial defect post brain injury was realized in the Department of neurosurgery of Saint-Paul hospital. Methods: from 10/1997 to 11/2004 , 124 patients skull defect after operation of traumatic brain injury underwent cranioplasty with carbon composite “intost-2”. there were 103 males (82.33%) and 23 females (17.66%) whose average age was 27 years (rang 5 to 55 years). 74 patients (51.61%) had an operation for acute subdural hematoma with or with out brain contusion and penetrating brain injury. One hundred one patient (81.45%) had large defect (>5cm) while 27 patients (21.77%) had very large defect (>8cm). Results: the operation successful rate was 98.39% (122/124). there were two infections because of cutaneous necrosis need secondary cranioplasty. Conclusion: The cranioplasty with carbon composite “intost-2” had good result in spite of large defect.
Brain Injuries
;
Surgery
10.Desensitive treatment for Dermatophagodes pteronyssinus allergen in allergic rhinitis
Journal of Practical Medicine 2005;503(2):24-27
Study on specific desensitive treatment for Dermatophagodes pteronyssinus allergen in 33 patients (mean age: 33.73+/-10.98) with allergic rhinitis at Central Otorhinolaryngology Hospital from November 2003 to October 2004. After treatment, all of clinical symptoms were reduced. Common effects on clinical treatmen were excellent in 24.3%, good in 45.5%, moderate 15.1% and bad in 15.1%. Before treatment, 100% patients had positive nose stimulation test and by 6 months of treatment, the rate only was 9.1%. After treatment, total IgE level in serum was lower than before treatment and total IgG level in serum was increased in comparison with before treatment. Common results after treatment: excellent 24.2%, good 48.5%, moderatel18.2% and bad 9.1%
Dermatophagoides pteronyssinus
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Rhinitis
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Hypersensitivity
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Allergens

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