The cyto-histologic correlation and cytologic accuracy are reported in thirty cases of consecutive aspirated cells and their biopsied tissues of patients with clinical and neuroradiologic evidences of central nervous system tumors and other lesions investigated at the Pathology and Neurosurgery Department, Korea University Hospital, from Apr. 1987 to Apr. 1988. The series comprised of 17 benign and 12 malignant histopathologically verified brain neoplasms and 1 infectious lesion. In 78% of the cases, the cytologic diagnosis was concordant with the histologic diagnosis provided adequate sample was obtained. In 17 benign tumors, the diagnostic rate was 87% ; the diagnostic accuracy for 12 malignant CNS tumors was 63% cytologically. In almost all cases, differentiation of non-neoplastic lesion from neoplastic one and that of benign tumors from malignant ones were possible. Most discordance stemmed from failure to distinguish different types of malignant tumors. In meningioma, neurilemmoma, pituitary adenoma, and medulloblastoma, cytologic diagnostic accuracy was high, but germinoma, malignant ependymoma, and hemangioblastoma were difficult to diagnose by cytology alone.

The authors analysed 92 patients who were operated with laminectomy and disectomy for herniated lumbar discs from August 1984 to July 1986 at the Depart. of neurosurgery, Korea University College of Medicine. The authors tried to grade the degeneration of nucleus pulposus pathologically in accordance with the severity of collagenosis and to correlate between these gradings with clinical and radiologic findings. The results were as follows, 1) Collagenosis seemed to be normal aging process of lumbar discs. 2) Duration of clinical symptoms, narrowing of the disc space and spur formation were correlated with the severity of collagenosis. 3) Sequestered discs seemed to promote the progression of collagenosis.
Aging ; Humans ; Korea ; Laminectomy ; Neurosurgery

Preliminary in vitro experiments were performed to define the contraction effects of the serotonin and prostaglandin F2 alpha in cat's internal carotid artery. Subsquently 12 cats were used to study changes in contractility resulting from pretreatment with reserpine. The arteries, which were exposed to serotonin and prostaglandin F2 alpha contracted significantly just after exposure time. And by addition of higher concentrated serotonin and prostaglandin F2 alpha more contractions were noted. Arteries isolated from reserpine-pretreated cats responded to the serotonin and prostaglandin F2 alpha with similar pattern to those seen in control groups, but the contractility showed some what more decreased slope compared to those with high concentration of serotonin only. These results suggested that reserpine might have yet unknown effects which were different from known mechnism of serotonin to cerebral arteries.
Animals ; Arteries ; Carotid Artery, Internal ; Cats ; Cerebral Arteries ; Dinoprost ; Reserpine* ; Serotonin

Vascular lesions involving the upper extremities have been treated by different route of upper thoracic sympathectomy with varying success. More recently, the anatomic and physiologic interest for autonomic nervous system has been progressively mounted but the surgical attack has plateau. It may be worthy for academic interest and clinical practice to estimate and to compare with the different surgical method. This paper concerns the treatment of a case suffering from atherosclerotic occlusion whom were treated by upper thoracic sympathetic ganglionectomy through the transaxillary transpleural route. This operation seems to be simpler than other surgical methods with lower morbidity, fewer complication and satisfying results.
Autonomic Nervous System ; Ganglionectomy ; Sympathectomy* ; Upper Extremity

No abstract available.
Emergencies* ; Hematoma, Subdural, Acute* ; Trephining*

The intracranial arachnoid cysts are benign lesions in nature which thin walled cysts lying in relation to or enclosed by the subarachnoid space, filled with clear fluid. They may be due to developmental defects of the brain or meninges and secondary to inflammation, vascular occlusion or trauma but etiology of a large percentage is not well understood. In general, locations are near primary fissure and cisterns of the cerebral cortex and cerebellum. The clinical features and courses are unusual. Preoperative diagnosis is unlikely to be made but treatment is followed by good result. We had experienced two cases of intracranial arachnoid cysts which occurs in middle cranial fossa, and cerebral hemisphere. Pathologic diagnosis are arachnoid cysts.
Arachnoid Cysts* ; Brain ; Cerebellum ; Cerebral Cortex ; Cerebrum ; Cranial Fossa, Middle ; Deception ; Diagnosis ; Inflammation ; Meninges ; Subarachnoid Space

Of the many potential source of free radial generation, the enzyme xanthine oxidase has been shown to be important in ischemia in non-cerebral tissues. Oxygen-derived free radicals have been implicated in various pathological conditions including ischemia. Xanthine oxidase serve as a source of oxidizing agents such as superoxide radical and hydrogen peroxide. It is investigated that the effect of a specific xanthine oxidase inhibitor, allopurinol, on infarct size in a model of continuous partial cerebral ischemia in rats. Infarct volume was measured by triphenyl tetrazolium chloride staining of brains removed 24 hours after middle cerebral arterial occlusion. Cortical tissue was more effectively protected than basal tissue, especially in allopurinol pretreated group. On histological examinations, hemispheric swelling, PMN cell infiltration and endothelial damage were noted irrespective of allopurinol treatment. It was speculated that free radicals are important in infarction secondary to partial continuous cerebral ischemia and that xanthine oxidase may by the primary source of these radicals.
Allopurinol* ; Animals ; Brain Infarction* ; Brain Ischemia ; Brain* ; Free Radicals ; Hydrogen Peroxide ; Infarction ; Infarction, Middle Cerebral Artery* ; Ischemia ; Middle Cerebral Artery* ; Oxidants ; Rats ; Superoxides ; Xanthine Oxidase

A ase of 47 years old female with cervical tuberculous spondylits involving C2,3 and C4 is reported. The lesion was treated surgically by curretage and anterior fusion with iliac bone autograft via median labiomandibular glossotomy.
Autografts ; Female ; Humans ; Middle Aged ; Spondylitis*

We have reported a case of acute spontaneous spinal epidural hematoma in a male patient aged 79-year-old who had suddenly felt a strong pain in the right buttock and lower abdomen. Shortly after he noticed weakness in his legs and two hours later he was completely paraplegic. Operation was undertaken 13 hours after the onset of the illness. A laminectomy was mode from T11 to L1 and a massive epidural hematoma removed mainly from the right posterolateral aspect of the cord.
Abdomen ; Aged ; Buttocks ; Hematoma ; Hematoma, Epidural, Spinal* ; Humans ; Laminectomy ; Leg ; Male

No abstract available.
Child* ; Humans ; Hydrocephalus*