No abstract available.
Diazepam* ; Hemodynamics* ; Morphine* ; Pancuronium* ; Respiration, Artificial*

No abstract available.
APACHE* ; Intensive Care Units* ; Critical Care*

Transcutaneous oxygen and carbon dioxide tension (PtcO2 and PtcCO2) measured with a heated electrode was compared with arterial owygen and carbon dioxide tension (PaO2 and PaCO2) in 5 groups of 37 patients admitted to the Intensive Care Unit, Severance hospital, from October 1985 to February, 1986. The results were as follows 1) In the group I (6 neonate patients), the PtcO2 and PtcCO2 index was 0.89. 1.02. The relationship of the two method is given br the regreasion equation(in mmHg) : PaO2= 1.15 (PtcO2) +0.77(r: 0.86 P<0.001) PaCO2=0.87 (PtcCO2) +5.12(r: 0.91 P<0.001) 2) In the group 2(13 mpmsirgocal patients) the PtcO2 and PtCO2 index was 0.71, 1.03. The relationship of the two methods is given by the regression equation(in mmH7) : PaO2 = 1.42(7t707) -0.27 (r: 7.53 p<0.001) rac07=1.73 (7tc007) -7.43 (r: 0.74 p<0.001) 3) In the group 3(8 immediate postopen heart patients) PtCO2 index was 0.20, PtcCO2 index was 1.25. There was no correlation between PtcO2 and PaO2. The relationship of the two method is given by the regression equation(in mmHg) : PaCO2= 0.40(ftcCO2) +2l. 68(r: 0.60 p<0,005) 4) In the Group 4(9 postpen heart patient after extubation) PtCO2 & PtCO2 index was 0.60, 1.05, and the relationship of the two method is given by the regression equation (in mmHg): PaO2 =1.92 (PtcO2)+67.26 (r=0.68 P<0.001) 7aCO2=0.64 (PtcCO2)+14.87 (r=0.66 p<0.001) 5) In the group 5(COPD Patient) the Ptco2 and rtcc09 index was 0.84, 1.04. and th? relationship of the two method is given br the regression equation(in mmHg) PaO2 = 1,10 (PtcO2) +7.35 (r=0.81 p<0.001) PaCO2=0.52 (PtcCO2) +21.59 (r: 0.63 P<0.001) Continuous montiroing can reveal large fluctuations in PaO2 and PaCO2 which would be missed by the use of intermittent arterial samples. The transcutaneous electrode can be employed usefully in the neonate and hemodynamic-allr stable adult patient in Intensive Care Unit. However this method is not recommended to the patients in shock, immediate postoper-ative patient with peripheral vasoconstriction and poor perfusion.
Adult ; Blood Gas Monitoring, Transcutaneous ; Carbon Dioxide ; Electrodes ; Heart ; Hot Temperature ; Humans ; Infant, Newborn ; Intensive Care Units ; Oxygen ; Perfusion ; Shock ; Vasoconstriction

Feasibility and neurologic complications accompanying spinal anesthesia with variable specific gravities were examined in 56 lumbar disc operation from March 1977 to October 1978. Patients' age ranged from 21 to 36 years with 54 cases of males and 2 females. On myelography, lateral and partial blocks were observed in 50 cases and total blocks in 6 cases. These cases were classified depending on the specific gravity and local anesthetics as follows: .Isobaric group: a) 1% tetracain solution, ampule, mixed with C.S.F., 20 cases. b) tetracaine powder with C.S.F., 11 cases. c) 10% procaine solution with C.S.F., 9 cases. .Hyperbaric group: 1% tetracaine solution with 10% dextrose in water, 10 cases. . Hypobaric group: tetracaine powder with water, 6 cases. Under isobaric, hyperbaric and hypobaric spinal anesthesia, good to excellent results were obtained in 90, 90 and 16.6% respectively. More than 10% of systolic blood pressure fall after block was seen in 15, 90 and 16.6% respectively. No neurologic sequalae were observed. Isobaric spinal anesthesia with tetracaine solution is indicated as safer for recently herniated lumbar disc operations.
Anesthesia, Spinal* ; Anesthetics, Local ; Blood Pressure ; Female ; Glucose ; Humans ; Male ; Myelography ; Procaine ; Specific Gravity ; Tetracaine ; Water

Air can be used as a carrier for volatile agent, ether, with a clear airway, normal pulmonary function and normal oxygenation. In 1858 John Snow, the Father of British Anesthesia stated in his book on Chloroform and Other Anesthetics that he believed it to be almost impossible for death to occur from ether administered with ordinary intelligence and attention. Today ether is probably still the safest anesthetic drug we possess. Ether is cheap and easily obtained; with controlled respiration 3% is adequate. Recovery smooth and rapid. Vomiting may be no different from other agents. Most machines depend upon cylinders of oxygen and other gases, and there are difficulties of refilling cylinders and the cost of transporting them. In such circumstances the E.M.O. Inhaler, allowing ether to be vaporized in known concentrations in air, has many advantages as an alternative to the open method administration. From all types of patients chosen at random 22 patients were studied for ether-air anesthesia. Anesthesia was induced with intravenous thiopental and subsequent endotracheal intubation was performed within 30 seconds with the aid of intravenous succinylcholine. SatO2, PaO2, pH, and Base E. were measured 3 times during pre-anesthesia, immediately after the intubation, and post-operatively by Radiometer, using the oxy-hemoglobin dissociation curve and the Siggard-Anderson alignment nomogram. Vital signs were recorded every 5 minutes. It is the purpose of this paper to present this series of 22 anesthetics by the use of the E.M.O. Inhaler with air and to discuss the possibility of hypoxia, advantages and limitations that became apparent. The results obtained may be summarized as follows. 1. It is essential that endotracheal intubation by carried out rapidly and that everything necessary be ready and immediately at hand before starting the anesthetic. 2. In all patients ventilated room air during anesthetic induction, no significant decreases of PaO2 and SatO2 were observed immediately after the endotracheal intubation. 3. The duration of any period of complete apnea inflicted on the patient must be carefully controlled. 4. 100% oxygen prevented the possibility of hypoxia on extubation after all the reflexes had returned. 5. Ether-air anesthesia is recommended without hesitation for use where economy and portability of anesthetic machine are needed.
Anesthesia* ; Anesthetics ; Anoxia ; Apnea ; Chloroform ; Ether ; Fathers ; Gases ; Hand ; Humans ; Hydrogen-Ion Concentration ; Intelligence ; Intubation ; Intubation, Intratracheal ; Nebulizers and Vaporizers ; Nomograms ; Oxygen ; Reflex ; Respiration ; Snow ; Succinylcholine ; Thiopental ; Vital Signs ; Vomiting

In order to determine the usefulness of Ketamine for the shocked patient, 31 cases were divided into 3 groups. Group 1: No hemorrhage or shock. Well maintained vital signs, 10 cases Group 2: Mild to moderate degree of hemorrhage. Fluid and blood replaced, 10 cases. Group 3: Hemorrhagic or septic shock state, 11 cases. The result of case analysis and change of vital sign after ketamine injection were as follows: 1. Physical status: Range of class of physical states in group 1, 2 and 3 were 1~3, 2~4 and 3~4 respectively, and 50% of group 1 and all cases of group 2 and 3 were emergency surgery. 2. Age distribution: The range of age distribution in groups 1, 2 and 3 was 23~62, 18~65 and 16~64 years old respectively. 3. Type of operation: In group 1, lobectomy, laparotomy and other operations were performed. Howrever in group 2 and 3, thoracotomy, laparotomy and other procedures were performed for hemostatic purposes. except one total hysterectomy for sepsis. 4. Premedicants: In one third of the total cases, mostly in group 1, secobarbital, meperidine or diazipam were: given. Atropire was given in 45% of the total cases, and 45%, mostly in group 2 snd 3, were not given any premedicants. 5. Anesthesia induction: Following preoxygenation, mastly in group 2 and 3, anesthesia was induced with ketamine (1~2 mg/kg) and intubation was done with succinylcholine, except for 3 cases in group 1. 6. Anesthesia maintenance: Ketamine as a sole anesthetic agent was given to 9 cases in operations of less than 1(1/2) hrs. duration. In other cases N2O or N2O with ether, halothane or methoxyflurane were administered according to the vital signs, and muscle relaxants (succinylcholine or gallamine) were given if necessary. 7. Duration of anesthesia: The range of duration of anesthesia in group 1, 2 and 3 was 40~360, 60~315 and 85~4845 min respectively. The average duration was 2.6, 2.5 and 4.3 hr in each group. 8. Blood and fluid replacement during anesthesia: The average blood replacement in each group was 259.6, 886.7 and 954.5 ml/hr for the entire surgical procedure, whole fluid replacement averaged 243.1, 228.0 and 432. 3 ml/hr respectively. 9. Hemoglobin: The range of Hb in preanesthetic state 8.2~14,9.5~12.8 and 7, 913.9 gm/dl in groups 1,2 and 3 and averaged 11 .8, 10.9 and 10.8. These Hb values increased after operation with blood and fluid to 12. 3, 11.0 and 12.3 gm/dl respectively. 10. Blood pressure: Before anesthesia the average systolic and diastolic Bp was 122.5/84.0, 94.5/68.0 and 108/79 mmHg in each group. Following the administration of ketamine, the systolic pressure increased 5.3, 14.3 and 26.7% respectively after 10 min. 11. Pulse rate: Change in pulse rate after ketamine injection was not significant in mast of cases. 12. Respiration: No remarkable change in respiration was observed however respiration was assiteded or controlled adequately through the anesthesia. With the above results, the rise of BP induced by ketamine during the induction period was found to be advantageous with such patients. We concluded that ketamine anesthesia for shocked patients of any etiology was safe, useful and satisfactory.
Age Distribution ; Anesthesia* ; Blood Pressure ; Emergencies ; Ether ; Halothane ; Heart Rate ; Hemorrhage ; Humans ; Hysterectomy ; Intubation ; Ketamine* ; Laparotomy ; Meperidine ; Methoxyflurane ; Respiration ; Secobarbital ; Sepsis ; Shock* ; Shock, Septic ; Succinylcholine ; Thoracotomy ; Vital Signs

Midazolam, a water-soluble benzodiazepine that is shorter-acting, more potent, and less irritating to veins than diazepam, has been suggested for use for induction of anesthesia. The cardiovascular effects of an induction dose(0.2~0.3mg/kg) of midazolam in ASA class lll cardiac surgical patients (N=15) were compared in a couble-blind fashion with a similar group of patients (N=15) receiving thiopental (5.0mg/kg). The patients were premedicated by triflupromasine, pethidine, hydroxyzine, atropine and diazepam. The results were summarized as follows. 1) The thiopental group were more decreased in blood pressure and increase in heart rates than midazolam group. 2) Spontaneous eye closing time and loss of eyelash reflexes were observed. But those were a poor sign of adequate induction became of heavy preanesthetic sedation. 3) The changes of blood pressure and pulse rate after induction and intubation were almost similar in the two groups, but greater individual variation was seen in midazolam groups, depends on preload state before induction. From the above results, midazolam was sufficient as an induction agent for open heart cases. But a hypovolemic patients and completely beta blocked patients should be used cautiously because they may be developed severe hypotension and tachycardia.
Anesthesia ; Atropine ; Benzodiazepines ; Blood Pressure ; Diazepam ; Heart Rate ; Heart* ; Humans ; Hydroxyzine ; Hypotension ; Hypovolemia ; Intubation ; Meperidine ; Midazolam* ; Reflex ; Tachycardia ; Thiopental ; Thoracic Surgery* ; Veins

Among the minor discomforts that occur as a result of intubation in the course of general anesthesia, sore throat was studied regarding its frequency and causal factors. Becausc of today's equipment and technique, endotracheal intubation has been greatly improved. Therefore, the incidence of postoperative sore throat has gradually been considerably reduced. Since surgical mortality was reduced strikingly in recent years, minor discomforts have been more important to the patients and anesthesiologists than before. We have studied sore throat in 239 cases of general anesthesia patients who have been operated in Severance Hospital between August 1, 1975 and September 30, 1975. and from April 1 to April 30, 1977. The results are as follows; 1. The incidence of sore throat after intubation in the course of general anesthesia was 20. 3% and female patients complained more of sore throat than male patients, 2. The incidence of sore throat increased according to the following conditions: a) When the muscle relaxation was poorer, b) When n ore attempts at intubation were needed, c) When larger tube sizes were used. 3. There was no significant difference in the in the incidence of sore throat between the rubber and the plastic tubes and no significant correlation between the incidence of sore throat and either the hours of intubation or the patients physical condition.
Anesthesia, General ; Clinical Study* ; Female ; Humans ; Incidence ; Intubation ; Intubation, Intratracheal* ; Male ; Mortality ; Muscle Relaxation ; Pharyngitis* ; Plastics ; Rubber

Pain in an extremity that develops following trauma, infection, thrombophlebitis and many other leaions has been recognized for years and designated by a variety of names. These syndromes appear to have the same physiopathology and response to therapy. All of them are characterized by exeessive unduly prolonged pain, vasomotor and other autonomic disturbances, delayed recovery of function and trophic changes. We have treated two cases of reflex sympathetic dystrophy. One case was only treated by stellate gangUon block repeated 26 times and the other case required surgical thoracic sympathectomy for complete recovery after 60 repeated stellate ganglion blocks. We report these two cases of reflex sympathetic dystrophy and review the literature.
Extremities ; Recovery of Function ; Reflex Sympathetic Dystrophy* ; Reflex* ; Stellate Ganglion ; Sympathectomy ; Thrombophlebitis

Twenty patients for abdominal surgery chosen at random were studied for postoperative pain relief with rectus sheath analgesia and meperidine by intramuscular injection. We wished to determine the efficacy of this new method of regional analgesia and to make a comparison it with that of systemic narcotics. At operation after surture of the posterior rectus sheath a specially designed 17 gauge polyethylene tube was positioned within the rectus sheath so that it lay in close proximity to the nerves supplying the surgical wound. The tube was designed to ensure even and uniform distribution of the local analgesics (2% lidocain 5 ml about 6 times on 1 st 24 hrs and 3 times on next 24 hrs) and it was removed after 48 hrs. The rectus sheath analgesia group of 15 patients was compared to a mepridine (50 mg) group of 5 patients. The effect of rectus sheath analgesia on pain relief and the patients ability to cough, to take deep breaths and to sit up were assessed subjectively by the same physician and objectively by each patient. In both groups pulmonary functions were assessed by measurements of arterial gases, tidal volume, minute volume, frequency, vital capacity, timed vital capacity, and peak expiratory flow rate(%). These measurements were assessed before and after operation and on the first and second postoperative days. Rectus sheath analgesia was found to reduce the degree of postoperative lung dysfunction. It is recommended in all debilitated patient with existing airway disease. It is concluded that rectus sheath analgesia is a reliable and simple method of controlling postoperative abdominal pain.
Abdominal Pain ; Analgesia* ; Analgesics ; Cough ; Forced Expiratory Volume ; Gases ; Humans ; Injections, Intramuscular ; Lung* ; Meperidine ; Methods ; Narcotics ; Pain, Postoperative ; Polyethylene ; Tidal Volume ; Vital Capacity ; Wounds and Injuries