1.Hypertension, Proteinuria during Pregnancy.
Journal of the Korean Medical Association 1998;41(4):431-435
No abstract available.
Hypertension*
;
Pregnancy*
;
Proteinuria*
2.Diagnosis and treatment of renal cystic diseases.
Korean Journal of Medicine 2002;63(6):727-730
No abstract available.
Diagnosis*
3.The effects of high glucose concentration on phospholipase A2 activity in cultured rat mesangial cells.
Kyu Hun CHOI ; Raphael A NEMENOFF
Korean Journal of Nephrology 1993;12(4):523-532
No abstract available.
Animals
;
Glucose*
;
Mesangial Cells*
;
Phospholipases A2*
;
Phospholipases*
;
Rats*
4.An Immunohistochemical Study of the Expression of Factor XIIIa , CD34 , and Mac 387 in Cutaneous Fibrous Tumors.
Hun JUNG ; In Kyung KANG ; Kyu Chul CHOI
Korean Journal of Dermatology 1995;33(6):1038-1045
BACKGROUND: The relationship and differentiation among various dendritic cells of the dermis are unclear. Recently it has hecome possible to identify different subpopulat,ions of dermal dendritic cells using anti-CD34 and anti-factor XIIIa antibodies. OBJECTIVE: To elucidate which cell types the fibrous dermal turnors consist of we compared the staining patterns of these antibodies as well as of anti-Mac 387 antibody which are labeled as inflammatory cells of the monocyte-macrophage lineage. METHODS: Tumors studied included dermatofibrosarcoma protuberans(DFSP, n=2), dermato-fibroma(n=22), neurofibroma, n=27), acrochordon(n=15), keloid, hypertrophic scar(n=10), juvenile xanthogranuloma(n=1, and malignant fibrous histiocytoma (MFH, n=1). We performed immunoperoxidase staining(AUSC technique) with polyclonal anti FXIIIa antibody, monoclonal anti-CD34 antibody, and monoclonal anti-Mac 387 antibody on the formalin-fixed-paraffin-embedded tissue specimens of these fibrous tumors. The intensity of staining was graded as negative, weakly staining, or strongly stainiring. RESULTS: FXIIIa reactivity was strongly present in dendritic and spindle-shaped cells of all dermatofibromas and some nurofibromas(11 of 27 specimens), but absent from the other fibrous tumors. Among these tumors, one of the two DFSPs was uniquely expressed CD34. Dendritic and spindle-shaped cells within tiese tumors were MAC 387 negative. In inflammatory conditions, variable numbers of MAC 38 positive cells were observed, corresponding to histiocytes and mac-rophages, but the labeling of ipithelioid cells and multinucleated foreign body giant cells were variable. CONCLUSION: The findings of significant numbers of FXIIIa positive cells in dermal fibrous tumors studied suggest that thet may be diagnostic utility associated with the use of this antit)ody. In addition, CD 34 expression by the tumor cells can be an extremely useful marker in establishing a definitive diagnosis of IFSP.
Antibodies
;
Dendritic Cells
;
Dermatofibrosarcoma
;
Dermis
;
Diagnosis
;
Factor XIIIa*
;
Giant Cells, Foreign-Body
;
Histiocytes
;
Histiocytoma, Benign Fibrous
;
Histiocytoma, Malignant Fibrous
;
Keloid
;
Langerhans Cells
;
Neurofibroma
5.A Case of Squamous Cell Carcinoma and Sebaceous Carcinoma Arising from Bowen' s Disease.
Jong Jun PARK ; Hun CHUNG ; In Kyung KANG ; Kyu Chul CHOI
Korean Journal of Dermatology 1995;33(3):575-579
Bowens disease is generally regarded as a premalignant dermatosis. If untreated, 3% to 5% of patients may develop squamous cell carcinoma. However, sebaciou carcinoma arising from Bowens disease is very rare. We presented a case of quarnous cell carcinoma and sebaceous circ s disease in a 68 year-old male. He had multiple bowenoid skin lesi nsties. A bean-sized nodule as developed on the bowenoid lesion of the he had a large yellow crust.ed exudative tumor on the Rt. thigh. We took a biopsy specimen of these three discrete lesions. The nu lipid stain of frozen section revealed Bowens disease, squarnous concllnoma arising from Bowen on the trunk and extremi Rt. lower abdomen. Almost of routine histology and carcinoma, and sebaceous carcinoma, respectively.
Abdomen
;
Aged
;
Biopsy
;
Bowen's Disease
;
Carcinoma, Squamous Cell*
;
Frozen Sections
;
Humans
;
Male
;
Skin
;
Skin Diseases
;
Thigh
6.Transarterial Guglielmi Detachable Coils Embolization with Stenting for the Treatment of a Traumatic Carotid Cavernous Fistula: Case Report .
Jung Yong AHN ; Hun Kyu CHOI ; Byung Hee LEE ; Eun Wan CHOI
Journal of Korean Neurosurgical Society 2002;32(2):156-158
Embolization of a carotid cavernous fistula(CCF) by means of a detachable balloon is a well-established method for treating CCFs while preserving a patent parent internal carotid artery(ICA). However, failure to embolize the CCF may occur on a few occasions. Herein we describe a stent-assisted Guglielmi detachable coil embolization that completely occludes the fistulous opening rather than fills the cavernous sinus. By applying this technique, we successfully treated a CCF, without compromise of the parent ICA in patients who has failed with balloon technique previously.
Cavernous Sinus
;
Embolization, Therapeutic
;
Fistula*
;
Humans
;
Parents
;
Stents*
7.Immediate oromandibular reconstruction by osteocutaneous free flap after composite resection.
Jang Su SUH ; Jin Kyu PARK ; Ywong Hun KWON ; Jae Sung CHOI ; Kyeong Jong CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):758-765
No abstract available.
Free Tissue Flaps*
8.The effect of hypertension on the progression of renal insufficiency in chronic renal failure patients.
Dae Suk HAN ; Kyu Hun CHOI ; Young Ki KIM ; Dong Hun CHA ; Ho Yung LEE ; Kyo Sun KIM
Korean Journal of Nephrology 1991;10(2):135-144
No abstract available.
Humans
;
Hypertension*
;
Kidney Failure, Chronic*
;
Renal Insufficiency*
9.The effect of hypertension on the progression of renal insufficiency in chronic renal failure patients.
Dae Suk HAN ; Kyu Hun CHOI ; Young Ki KIM ; Dong Hun CHA ; Ho Yung LEE ; Kyo Sun KIM
Korean Journal of Nephrology 1991;10(2):135-144
No abstract available.
Humans
;
Hypertension*
;
Kidney Failure, Chronic*
;
Renal Insufficiency*
10.Changes of serum and dialysate leptin levels in continuous ambulatory peritoneal dialysis patients.
Korean Journal of Medicine 2007;73(2):119-122
Leptin, the product of the adipose-specific ob gene, regulates food intake and energy expenditure in animal models. It is well known that serum leptin levels are increased in patients with chronic renal failure before start of dialysis or even after dialysis. This disorder is basically mediated by a decrease in the renal clearance of leptin, whereas the potential role of an increased secretion of this hormone awaits further confirmation. In this issue of the Journal, Park and Do investigate the longitudinal changes in body composition, serum(S) and dialysate(D) leptin levels in CAPD patients with time. There are significant increases in fat mass, S and D leptin at the 12th month after initiation of PD, especially in diabetes. Factors associated with the changes of fat mass during the first 1 year are D/Plasma 4-hour creatinine, glucose absorption via peritoneal cavity, and duration of dialysis. The correlation between changes of S or D leptin and %fat mass is significant. Consequently, they conclude that increased leptin levels of serum and dialysate may be associated with fat mass in PD patients with time. They found much further increase of D leptin concentration than S leptin, suggesting the possibility of intraperitoneal production of leptin. The molecular weight of leptin is small enough to pass through the peritoneum. Therefore, the extent of S leptin cleared by PD and/or whether a significant intraperitoneal leptin production occurs during PD with glucose-rich solution should be studied. It is well documented that the continuous glucose load during PD will result in chronic hyperinsulinemia which has been shown to increase leptin level by about 40%. Increased generation of proinflammatory cytokines, which is a common feature of PD, may also be a factor stimulating leptin gene expression. The relationship between insulin or proinflammatory cytokine and leptin concentration in PD patients is worthy of further study. In addition, the finding that the dialysate concentration of vascular endothelial growth factor potentially mediating neovascularization in the peritoneal cavity positively correlate with the increase of D/S leptin during the 1st year deserve consideration.
Absorption
;
Body Composition
;
Creatinine
;
Cytokines
;
Dialysis
;
Eating
;
Energy Metabolism
;
Gene Expression
;
Glucose
;
Humans
;
Hyperinsulinism
;
Insulin
;
Kidney Failure, Chronic
;
Leptin*
;
Models, Animal
;
Molecular Weight
;
Negotiating
;
Peritoneal Cavity
;
Peritoneal Dialysis
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritoneum
;
Vascular Endothelial Growth Factor A