No abstract available.
Craniocerebral Trauma* ; Head*

Trichophyton(T.) verrucosum had not been reported until now in Korea. We report herein a case of kerion celsi caused by T. verrucosum considered the first case in Korea and its epidemiologic enviroment. She was a 10 years old girl living in cattle country. Three weeks ago, three small erythematous nodules were developed and rapidly progressed to be large boggy mass like tumefactions. Histopathologically, fungal hyphae and spores were found in hair follicles in H & E and PAS stain. In fungal study, characteristic features of T. verrucosum were found as chains of chlamidospores et als. With above results, we could diagnose these lesions as kerion celsi caused by T. verrucosum which were transmitted from a cattle. After 4 weeks-administration of ketoconazole, lesions were healed completely.
Animals ; Cattle ; Child ; Epidemiologic Studies* ; Female ; Hair Follicle ; Humans ; Hyphae ; Ketoconazole ; Korea ; Spores ; Tinea Capitis* ; Trichophyton*

We reported a case of 22 years old male with perifolliculitis capitis abscedens et suffodiens. He had multiple fistular tracts, abscess, and cicatrized alopecia on the vertex and occiput. Compressing the abscess lesion, pus discharge was shown. Also he had acne conglobata and acne vulgaris on the face and nuchal area. On the bacterial culture, coagulase positive Staphylococcus aureus was isolated. These lesions were persistent in spite of frequent incision and drainage and antibiotic therapy. Considering it having a pathogenesis like acne conglobata, we tried him 13-cis-retinoic acid that had good effect in the treatment of cystic or conglobate acne. Three months after treatment, the lesions disappeared completely.
Abscess ; Acne Vulgaris ; Alopecia ; Coagulase ; Drainage ; Humans ; Isotretinoin ; Male ; Staphylococcus aureus ; Suppuration ; Tretinoin* ; Young Adult

The V-to-T plasty was developed by Field(1985), of which purposes are to place scars in natural wrinkle lines, be hidden by natural anatomic landmarks, and, if possible, attain symmetry. The authors reported a case of basal cell carcinoma arising at the upper lip of 66 years old male, We treated him with V-T plasty using the natural landmarka and wrinkle lines around the upper lip and the nose, Two weeks after operation, we attained excellent funtional and cosmetic results. So we recommended its method to operate tumors arising at forehead, upper & lower evelid, upper and lower lip, both preauricular area, etc.
Aged ; Anatomic Landmarks ; Carcinoma, Basal Cell* ; Cicatrix ; Forehead ; Humans ; Lip ; Male ; Nose

Although methidathion is an organophosphate insecticide, it is different from the other organophosphates in terms of toxicity. Because of its relatively high fat solubility, the apparent volume of methidathion distribution throughout the body is very high, indicating that hemoperfusion is not effective in removing this organophosphate from the body. Redistribution of methidathion from fat to blood can also occur when plasma levels diminish. Additionally, acetylcholinesterase aging, which is the loss of an alkyl side chain that prevents reactivation by oximes, is very rapid so that the effective reactivation by oximes is thwarted. Thus, methidathion's effect on acetylcholinesterase inhibition is long lasting, particularly with a high dose. In addition to its parasympatholytic effect and ability to induce muscle paralysis, methidathion poisoning is associated with a profound and long-lasting circulatory collapse due to sympathetic ganglion blockade. This report presents the case of a 55-year-old man who accidentally ingested a high dose of methidathion. He later developed enteroinvasive aspergillosis infection-induced multiple bowel perforations on two separate occasions while on mechanical ventilator support, resulting in a fatal outcome. The renin-angiotensin axis activated by sympathetic ganglion blockade may have reduced the patient's splanchnic blood flow, contributing to translocation of endotoxin. Also, the effect of excessive acetylcholine on non-neuronal acetylcholine receptors may have contributed to the development of fatal enteroinvasive aspergillosis in this patient.
Acetylcholine ; Acetylcholinesterase ; Aging ; Aspergillosis ; Fatal Outcome ; Ganglia ; Ganglia, Sympathetic ; Hemoperfusion ; Humans ; Middle Aged ; Organophosphate Poisoning ; Organophosphates ; Oximes ; Paralysis ; Parasympatholytics ; Plasma ; Poisoning* ; Receptors, Cholinergic ; Shock ; Solubility ; Ventilators, Mechanical

Gangrenous skin disease is characterized by rapidly progressive necrosis of the subcutaneoua tissue. It is mainly caused by Group A b-hemolytic Streptococcus. We are now reporting three cases of gangrenous skin diseases including gangrene due to Vibrio vulnificus, streptococcal gangrene, and ecthyma gangrenosum. Their treatment was as follows: early surgical debridment, the correction of fluidelectrolyte depletion, and antibiotics. When fresh granulation tissues were seen on the wound base, we performed so called Island skin graft. 3 to 5 weeks later, there were good cosmetic and functional results. These results reveals that among several curative measures of gangrenous skin diseases early surgical debridment is the most important one. We belive many dermatologists should be concerned about skin surgery progressively.
Anti-Bacterial Agents ; Dermatologic Surgical Procedures ; Ecthyma ; Gangrene ; Granulation Tissue ; Necrosis ; Skin Diseases* ; Skin* ; Streptococcus ; Transplants* ; Vibrio vulnificus ; Wounds and Injuries

Two cases of congenital multiple joint laxity are reported here. One was a 18-year-old boy, in whom the hypermobility of the joints was striking that 4 criterias (Carter & Wilkinson, 1964) could be observed. The other was a 18-year-old male who showed positive findings in three of the five diagnostic criterias. In both no familiar occurrence was noted.
Adolescent ; Humans ; Joint Instability ; Joints ; Male ; Strikes, Employee

BACKGROUND: thermotherapy has been shown to be effective in the treatment of some fungal infections. Dermatophyte are well grown at 25degrees C rather than 37degrees C or high temperature. OBJECTIVE: An vitro test was done to assess the complemental effect and optimal conditions of local heating on the susceptability of t. rubrum to systemic antifungal agents. METHODS: Microdilution susceptability test to ketoconazole and itraconazole was done using 96 well microplate. Eight strains of T. rubrum were isolated from patients withtinea pedis and were cultured at 25degrees C, 37degrees C and 42degrees C for 1, 8 or 24 hours per day. MIC were checked at 4th, 7th, 9th day after inoculution. RESULTS: The growth without antifungal agents at 37degrees C and 42degrees C were decreased by 805 and 50% of the growth at 25degrees C respectively. Seven day after inoculation was the proper time to check the MIC. MIC50 of ketoconazole was the lowest at 42degrees C for 24hours per day in value of 0.006microgram/ml, and 0.09microgram/ml at 37degrees C for 24hours per day, 0.37microgram/mlat 42degrees C, for 8hours per day and 37degrees C for 8hours per day. MIC at 42degrees C for 1 hours er day, 37degrees C for 1 hyours and 25degrees C for 24hours per ady MIC were the same in value of 0.05microgram/ml. MIC50 of itraconazole was the lowest at 42degrees C for 24hours per day in value of 0.006microgram/ml, 0.01microgram/ml at 37degrees C for 24hours per day, 0.02microgram/ml at 37degrees C for 8hours per day. MIC at 42degrees C for 8hours per day, 42degrees C for 1hours per day, 37degrees C for 24hours per day MIC were the same in value of 0.05microgram/ml. CONCLUSION: Incubation at 37degrees C for 24 hours per day or 42degrees C for 24 hours per day increased the susceptability of T. rubrum to ketoconazole and itraconazole.
Antifungal Agents* ; Arthrodermataceae* ; Complement System Proteins ; Heating ; Hot Temperature ; Humans ; Hyperthermia, Induced ; Itraconazole ; Ketoconazole

No abstract available.
Colon* ; Rectum*

We report a case of 17-year-old female with juvenile onset systemic lupus erythematosus Who developed symptomatic unilateral sacroiliitis. She had neither HLA-DR3 nir B27 antigens. Though sacroiliitis have been reported in mail SLE patient. it has been rarely reported in female patients. The rare coexistence of SLE and sacroiliitis. described in this case. may not be determined soley by genetic factors; sacroiliitis may be just an infrequent manifestation of SLE.
Adolescent ; Female* ; HLA-DR3 Antigen ; Humans ; Lupus Erythematosus, Systemic* ; Postal Service ; Sacroiliitis*