1.Clinical Considerations of Intoxication Caused by a Herbicide Containing Glufosinate Ammonium: 6 Cases Analysis.
Ji Hun KANG ; Young Ho JIN ; Jae Baek LEE
Journal of the Korean Society of Emergency Medicine 1998;9(4):652-658
Basta(R) is one of the Phospho-amino acid group herbicide. It consist of glufosinate ammonium (18.5%), alkylether sulfate as surfactant (30%) and some solvents. Although it's WHO classification is Bade III, the intoxicated patient appears an serious clinical findings and have a 20% mortality rate. Nowadays, in Korea the ingestion of herbicidal agents for suicidal attempts is Sequent. The literature for intoxication of bipyridilium (Gramoxon(R)) as herbicide is varied, but the information for Basta(R) is poor even though the use of it tends to increase. Recently, We experienced six cases of Basta(R) intoxication and found that the patient expressed a gradually progressed depression of mentation, recent memory disturbances, convulsions, hypotension, or bradycardia because of CNS or cardiovascular effects of Basta(R) We report these cases with literature review.
Ammonium Compounds*
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Bradycardia
;
Classification
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Depression
;
Eating
;
Humans
;
Hypotension
;
Korea
;
Memory
;
Mortality
;
Seizures
;
Solvents
2.Tendon Transfer with a Miarovascular Free Flap in Injured Foot of Children.
Soo Bong HAHN ; Jin Woo LEE ; Jae Hun JEONG
The Journal of the Korean Orthopaedic Association 1997;32(1):92-100
We performed tendon transfer with a microvascular free flap for recovery of handicapped function and reconstruction for the skin and soft tissue loss. We review the clinical data of 11 children who underwent these operation due to injured foot by pedestrian car accident from January, 1986 to June, l994. The mean age of patients was 5.6 years old (3-8). Five cases underwent tendon transfer and microvascular free flap simultaneously. Another 6 cases underwent operations separately. The time interval between tendon trasnfer and microvascular free flap was average 5.8 months (2-15 months). The duration between initial trauma and tendon transfer was average 9.6 months (2-21 months). The anterior tibial tendon was used in 6 cases. Among these, the technique of splitting the anterior tibial tendon was used in 5 cases. The posterior tibial tendon was used in 3 cases and the extensor digitorum longus tendon of the foot in 2 cases. Insertion sites of tendon transfer were the cuboid bone in 3 cases, the 3rd cuneiform bone in 3 cases, the 2nd cuneiform bone in I case, the base of 4th metatarsal bone in I case, and the remnant of the extensor hallucis longus in 3 cases. The duration of follow-up was average 29.9 months (12-102 months). The clinical results were analyzed by Srinivasan criteria. Nine cases were excellent and 2 cases were good. The postoperative complications were loosening of the tranferred tendon in 2 cases, plantar flexion contracture in l case, mild flat foot deformity in I case and hypertrophic scar in 2 cases. So we recommend the tendon transfer with a microvascular free flap in the case of injured foot of children combined with nerve injury and extensive loss of skin, soft tissue and tendon.
Child*
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Cicatrix, Hypertrophic
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Congenital Abnormalities
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Contracture
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Disabled Persons
;
Flatfoot
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Follow-Up Studies
;
Foot*
;
Free Tissue Flaps*
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Humans
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Metatarsal Bones
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Postoperative Complications
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Skin
;
Tarsal Bones
;
Tendon Transfer*
;
Tendons*
3.Proper selection of patients with polycystic ovarian disease for intermediate dose pure FSH.
Jang Heub KIM ; Eun Jung KIM ; Jin Hong KIM ; Jin Woo LEE ; Hun Young LEE
Korean Journal of Obstetrics and Gynecology 1992;35(1):97-102
No abstract available.
Female
;
Humans
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Ovarian Diseases*
4.A Case of Trichoadenoma:Occurrence of a Rare Site and Immunohistochemical Staining Pattern of CD34.
Jong Min KIM ; Sang Hun LEE ; Hyong Jin KIM ; Ho Gyun LEE ; Jin Hee SOHN
Annals of Dermatology 1997;9(2):167-170
Trichoadenoma is a rare tumor with differentiation towards the infundibular portion of the pilosebaceous canal. Clinically, it is a nodular growth, usually on the face and buttock. Histologically, it is characterized by numerous horn cysts lined with squamous epithelium in the dermis. In this report, we describe a 44-year-old man who developed trichoadenoma on his right shin. Anti-CD34 antibody stained spindle-shaped cells in the stroma just adjacent to the peripheral layers of keratinous cysts and solid masses of squamous epithelial cells. To our knowledge, this is the first description of an occurrence of trichoadenoma in the lower leg and the first to use immunohistochemical staining to know the CD34 staining pattern.
Adult
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Animals
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Buttocks
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Dermis
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Epithelial Cells
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Epithelium
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Horns
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Humans
;
Leg
5.The Analysis of Epithelial Ingrowth after LASIK Using a Femtosecond Laser.
Hee Jin JUNG ; Sang Won KIM ; Tae Hun LEE ; Kyung Hun LEE
Journal of the Korean Ophthalmological Society 2011;52(12):1434-1439
PURPOSE: To analyze the incidence and clinical course of epithelial ingrowth after laser in situ keratomileusis (LASIK) using a femtosecond laser. METHODS: We retrospectively evaluated the results of 1158 eyes of 581 patients who received LASIK with the flap created by a femtosecond laser from February 2006 to March 2009 at our institute. We investigated the incidence and clinical course of LASIK in which the flap was created by a femtosecond laser. RESULTS: Epithelial ingrowth was first detected one week after surgery in 12 (57%) of 21 eyes and within one month in 19 eyes (90%). Epithelial ingrowth was localized most commonly near the temporal and nasal flap edge in 12 eyes (57%). In two eyes (9.5%), an isolated ingrowth mass was located in the pupillary area. The development of more than 2.0 mm of epithelial ingrowth was observed in three eyes (0.25%). Among 28 eyes with loose epithelium or epithelial detachment during surgery, epithelial ingrowth was observed in six eyes (21.4%) compared with 15 (1.32%) of 1130 eyes without loose epithelium or epithelial detachment. Therefore, epithelial detachment during surgery was significantly associated with epithelial ingrowth (p = 0.00). CONCLUSIONS: In LASIK in which the flap is created by a femtosecond laser, damage to the epithelial layer increases the chances of epithelial ingrowth. Therefore, avoiding epithelial defects with a gentle maneuver is needed to reduce the chance of epithelial ingrowth during surgery.
Epithelium
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Eye
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Humans
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Incidence
;
Keratomileusis, Laser In Situ
;
Retrospective Studies
6.RECONSTRUCTION OF FINGER DEFECTS WITH PEDICLED VENOUS ISLAND FLAP.
Jong Rok LEE ; Sang Hun CHUNG ; Jin Soo LIM ; Young Jin KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(2):340-347
Reconstruction of a injured digit needs good aesthetic result as well as functional recovery. Since Honda deported the first clinical application in 1984, the venous flap has been used increasingly for skin and soft tissue defects of the fingers and hands. From november 1992 to december 1995, 12 single-pedicled venous island flaps from hand dorsum were used for coverage of soft tissue defects of fingers over exposed bone, tendon, or joint. The pedicle of the flap included one superfitial dorsal vein of hand and its perivenous areolar tissue. Eight of twelve flaps survived completely and four necrosed partially possibly due to excessively long pedicle and poor perivenous areolar tissue. All donor sites were closed directly. Most patients were satisfied with postoperative result cosmetically and functionally. This method has several advantages : easy versatility and operability with superficial location of numerous dorsal vein, making good contour owing to proper thickness of flap, minimal donor site morbidity, and short operation time. We consider that the pedicled venous island flap is another reliable and useful method for reconstruction or finger defects as long as the pedicle length is not long and the perivenous areolar tissue is enough.
Fingers*
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Hand
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Humans
;
Joints
;
Skin
;
Surgical Flaps
;
Tendons
;
Tissue Donors
;
Veins
7.Comparison of depression, anxiety and stress levels between non ulcer dyspepsia group and control group.
Jong Yeal LEE ; Byeong Seon CHO ; Ga Young LEE ; Tae Jin PARK ; Bong Hun CHOI
Journal of the Korean Academy of Family Medicine 1997;18(4):411-423
BACKGROUND: Non ulcer dyspepsia(NUD) is a commonly encountered disease at the primary practice. The relations of functional gastrointestinal disorder and Irritable bowel syndrome with depression or stress were suggested by previous studies. But the contributions of the anxiety, depression and stress as a whole to the NUD were not assessed. In this study, we wanted to show the associations of the anxiety, depression and stress levels with NUD. METHODS: This study was performed by case and control method from Aug. 1 to Sep. 7 at the outpatient department of Family Medicine and at the Health Management and Service department in Pusan Paik Hospital. The both groups were matched by sex and age. The case was defined who has three or more symptoms among nine upper gastrointestinal symtoms like dyspepsia, epigastric pain and anorexia etc. frequently or alwalys and who has no ulcer at the gastrofibroscope. The anxiety, depression, stress levels were measured by questionnaire which was validated by previous studies. The questionnaire was composed of Trait-STAI, Jung's Self Depression Scale(SDS), Modified BEPSI, and Grobal Assessment of Recent Stress(GARS) Scale. RESULTS: The total subjects were 136 persons(NUD group : 86 persons/control group : 86 persons). There were. significant differances in regularity of diet(P<0.001), levels of education(P=0.009), and history of medications(P<0.001) between two groups. The two group had higher scores than the control group in the depression score, anxiety score and modified BEPSI score(P<0.001). All items in GARS showed higher scores in NUD group than in control group(P<0.001). CONCLUSIONS: NUD group had higher degree of anxiety and depression than the control group. It seems that the NUD may have streeful status. When we encounter the NUD in outpatiet department, we had better consider the underlying psychogenic or stressful conditions.
Anorexia
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Anxiety*
;
Busan
;
Depression*
;
Dyspepsia*
;
Gastrointestinal Diseases
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Humans
;
Irritable Bowel Syndrome
;
Outpatients
;
Ulcer*
;
Surveys and Questionnaires
8.Median Raphe Cyst of the Penis.
Won hyoung KANG ; Seung Hun LEE ; Jin Soo KANG ; Sung Nack LEE
Korean Journal of Dermatology 1981;19(6):951-955
Median raphe cyst is not a cornmon disease and represents a defect in the embryologic development of male genitalia. It occurs most commonly near the glans penis, but may occur anywhere from the urethral meatus to the anus, and is lined by entodermal or ectodermal epithelium. Surgical excision is the treatment of choice. Recently we observed a 29-year-old male patient who had had a typical median raphe cyst since childhood on the ventral aspect of the glans penis. On histological examination, the cyst was lined by stratified columnar epithelium varied from four to eight cells in thickness.
Adult
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Anal Canal
;
Ectoderm
;
Epithelium
;
Genitalia, Male
;
Humans
;
Male
;
Penis*
9.Expression of Met Protein in Colorectal Carcinoma.
Kyung Un CHOI ; Jin Sook LEE ; Chang Hun LEE ; Mee Young SOL ; Kang Suk SUH
Korean Journal of Pathology 2000;34(7):501-508
Met protein is a transmembrane 190 kD heterodimer with tyrosine kinase activity, encoded by c-Met oncogene. It serves as a high affinity receptor for hepatocyte growth factor (HGF)/scatter factor (SF), a cytokine which stimulates cell proliferation, motility, and invasion. In this study, we immunohistochemically evaluated the expression of Met/hepatocyte growth factor receptor in colorectal cancers. Met protein was expressed in 31 of 72 patients (43.1%). The staining pattern was cytoplasmic in nature, present throughout the tumor, and showed variable intensity from case to case. The relationship between the expression rate and intensity, and age and sex of patients, tumor size (p=0.645), tumor site (p=0.902) and tumor differentiation (p=0.844) was not statistically significant. The expression rate and intensity were significantly correlated with lymphovascular invasion (p=0.001), lymph node metastasis (p=0.010), depth of invasion (0.019), and stage (p=0.023). Cytoplasmic accumulation of Met protein was not associated with enhanced PCNA index of tumor cells (p=0.052). These results suggest that Met protein may play an important role in the invasion and metastasis of colorectal cancer cells.
Cell Proliferation
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Colorectal Neoplasms*
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Cytoplasm
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Hepatocyte Growth Factor
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Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Oncogenes
;
Proliferating Cell Nuclear Antigen
;
Protein-Tyrosine Kinases
10.A case of cutaneous metastasis from carcinoma of the urinary bladder.
Sung Ku AHN ; Jin Hyong WON ; Ho KWACK ; Seung Hun LEE ; Sungnack LEE
Korean Journal of Dermatology 1991;29(2):271-274
A 70 year-old male visited with 1 month history of dark brown, hard, non-movable subcutaneous nodule on the anterior chest. Histopathologic findings were compatible with the metastatic transitional cell carcinoma of the urinary bladder.
Aged
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Carcinoma, Transitional Cell
;
Humans
;
Male
;
Neoplasm Metastasis*
;
Thorax
;
Urinary Bladder*