Carotid angiography is a most important diagnostic procedure for investigation of intracranial lesions and for understanding the cerebral circulation. Of the cerebral arteries, only the posterior cerebral artery is, both functionally and anatomically, a border artery between the carotid and vertebral circulatory systems, so it is more important for an understanding of the cerebral circulation. Early in the development of the fetal circulation, the posterior cerebral artery arises from the internal carotid artery(carotid segment), with the connection to the basilar artery(basilar segment) developing later. In many cases, however, it derives its supply from both systems simultaneously. Angiographic demonstration of the posterior cerebral artery is influenced by certain pressure factors of the intracranial cavity and other technical factors, for example, site of puncture, needle size, injection time and force used and position of the head, ect. Here the author has analysed the factors of age, sex, puncture site and right of left side and a degree of hydrocephalus. Carotid angiography has been performed for definite indication, hence, no cerebral angiography has been performed on any entirely asymptomatic subject. The normal controls used in this investigation consist of angiographies done in subjects with symptoms but no evidence of vascular lesions or other abnormality. The author found a high incidence of the posterior cerebral arteries demonstrated in hydrocephalus, in spite of increased pressure and changed courses of the cerebral arteries. So, the cerebral arteriograms of normal cases are compared with those of hydrocephalic subjects and the chances of demonstrating the posterior cerebral artery in both groups are analysed. Engeset A.(1948), Saltzman(1959), Yasargil & Krayenbuhl(1964) and others reported the demonstration of the posterior cerebral artery but report of a relationship of the artery with hydrocephalus was not found. This study comprises 2,350 conventional carotid angiographies carried out from 1968 to 1973 in the neurosurgery department of Severance Hospital, Seoul, Korea. Out of these 2,350 angiographies, 1,288 were normal and 160 were indicative of hydrocephalus. The incidence of angiographic demonstration of the posterior cerebral artery in normal Koreans is 34.2% and in hydrocephalus, 45.6%. This is a higher incidence than is reported in the literature concerning conventional carotid angiography. The number of cases where the posterior communicating artery alone was filled was so small that there was no point in separating them according to age and sex, etc. Generally the hydrocephalic group showed a higher incidence of the posterior cerebral and posterior communicating arteries than the normal group. In all cases, the effect of sex difference is not significant but the effect of age is. The posterior cerebral artery was more visible in the younger groups and occurred most frequently in the youngest group, while the incidence dropped slightly in the higher age groups, in both normal and hydrocephalus groups. Filling of the posterior cerebral arteries in subjects aged 10-30 is markedly more frequent than in the 40-60 age range in both the normal and hydrocephalus groups. The posterior cerebral artery was demonstrated in 148 out of 384(38.6%) internal carotid arteriograms and in 292 out of 904(32.3%) common carotid arteriograms. This difference is highly significant and is similar to the results of Saltzman(1959). No significance of the right or left side difference could be found. The increasing tendency of the filling of the posterior cerebral artery in the more severe forms of hydrocephalus compared with the milder types was noted. In this report, the statistical significance was evaluated by means of the z-test.
Angiography ; Arteries* ; Cerebral Angiography ; Cerebral Arteries ; Head ; Humans ; Hydrocephalus* ; Incidence ; Korea ; Needles ; Neurosurgery ; Posterior Cerebral Artery ; Punctures ; Seoul ; Sex Characteristics

In 1921, Dandy discussed the clinical diagnosis and treatment of hydrocephalus secondary to occlusion of the foramina of Magendie and Luschka. In 194, Walker reported a case of congenital atresia of the outlets of the fourth ventricle treated surgically. Since a detailed study of this disease entity by Benda in 1954, the condition has commonly been known by the term, the Dandy-Walker syndrome. In 1968, Raimondi and et al refered this condition as the Dandy-Walker cyst. There is considerable discussion as to the nature of the fundamental embryologic error in this condition, but Denda suggested that atresia of developing fourth ventricular foramina was only a part of the syndrome and not its cause, because in some cases reported, the foramina were found to be patent. These patients. Show characteristic clinical symptoms, signs and radiological findings and should suggest the correct diagnosis. This syndrome was one of the first cause of hydrocephalus to be treated successfully by surgery. We are reporting one case of this cyst encountered recently at Yonsei University Medical Center.
Academic Medical Centers ; Dandy-Walker Syndrome* ; Diagnosis ; Fourth Ventricle ; Humans ; Hydrocephalus

In 1921, Dandy discussed the clinical diagnosis and treatment of hydrocephalus secondary to occlusion of the foramina of Magendie and Luschka. In 194, Walker reported a case of congenital atresia of the outlets of the fourth ventricle treated surgically. Since a detailed study of this disease entity by Benda in 1954, the condition has commonly been known by the term, the Dandy-Walker syndrome. In 1968, Raimondi and et al refered this condition as the Dandy-Walker cyst. There is considerable discussion as to the nature of the fundamental embryologic error in this condition, but Denda suggested that atresia of developing fourth ventricular foramina was only a part of the syndrome and not its cause, because in some cases reported, the foramina were found to be patent. These patients. Show characteristic clinical symptoms, signs and radiological findings and should suggest the correct diagnosis. This syndrome was one of the first cause of hydrocephalus to be treated successfully by surgery. We are reporting one case of this cyst encountered recently at Yonsei University Medical Center.
Academic Medical Centers ; Dandy-Walker Syndrome* ; Diagnosis ; Fourth Ventricle ; Humans ; Hydrocephalus

Malignant melanoma of the spinal cord is a rare tumor 3,8,9,12 The melanomas that originate in the meninges bear a general structural resemblance to those arising elsewhere, but it is questionable whether they ever metastasis outside the central nervous system7. If can be also argued that the primary central nervous system melanoma could actually be a metastasis from an occult primary site in the skin, esophagus, rectum or other sites6. We are reporting a case of malignant melanoma involving the cervical spinal meninges and hard palate.
Central Nervous System ; Esophagus ; Melanoma* ; Meninges ; Neoplasm Metastasis ; Palate, Hard ; Rectum ; Skin ; Spinal Cord*

No abstract available.
Abruptio Placentae* ; Female ; Pregnancy

No abstract available.
Cesarean Section* ; Female ; Pregnancy

BACKGROUND: Reactive oxygen species (ROS) induce lipid peroxidation and tissue damage in the isolated rabbit thoracic aorta. The aim of this study was to explore the influence of the propofol and midazolam against ROS in the isolated rabbit thoracic aortic endothelium. METHODS: Eighteen white male rabbits (weighing 2.0-2.5 kg) were used. The thoracic aorta was dissected free and cut into rings (3-4 mm) and then suspended in a organ bath filled with 10 ml Krebs solution bubbled with 5% CO2 95% O2 at 37 degrees C. Aortic rings were then equilibrated for 90 min, and a resting tension of 1.5 g was applied. The Krebs solution was changed every 15 min. Isometric tension was recorded with transducer coupled to a data acqusition system (Biopac Inc. USA) on a PC. After precontraction with norepinephrine (NE, 10(-6)M), changes in tension were measured following the cumulative administration of acetylcholine (ACh 3x10(-7), 10(-6) and 3x10(-6)M) and nitroglycerin (NTG, 10(-5)M). Data are expressed as percentage of the 10 5 M NTG-induced relaxation (ACh/NTG). The ACh/NTG, before and after electrolysis were defined as the control and the experimental groups. The aortic rings were pretreated with propofol (3x10(-5), 10(-4), 3x10(-4) and 5.7x10(-4) M, n = 8, 10, 15, 13), midazolam (10(-4)M, n = 7), catalase (1,000 U/ml, n = 12), mannitol (3x10(-4)M, n = 5) or not pretreated group (Free, n = 6). After 30 minutes, the aortic rings were exposed to ROS generated by electrolysis (DC 9 V, 20 mA, aortic rings 1 cm away from electrode) in Krebs solution for 2 minutes, which was then changed for physiologic buffered salt solution. The aortic rings were precontracted with NE and vasorelaxation was induced with ACh and NTG at the above mentioned concentrations. RESULTS: Propofol produced vasorelaxation of NE-precontracted thoracic aorta in a dose-dependent fashion in all groups of propofol (3x10(-5), 10(-4), 3x10(-4) and 5.7x10(-4)M) even after ROS attack (P < 0.05 vs control value). Catalase produced vasorelaxation after ROS attack (P < 0.05 vs control value).On the other hand, ACh-induced significant endothelium-dependent vasorelaxation were not observed in the midazolam or mannitol pretreated group or the non-pretreated group (P <0.05 vs control group). CONCLUSIONS: These findings suggest that propofol and catalase preserve ACh induced endothelium-dependent vasorelaxation and that propofol has a concentration dependent ROS scavenging effect like catalase.
Acetylcholine ; Aorta, Thoracic ; Baths ; Catalase ; Electrolysis ; Endothelium ; Hand ; Humans ; Lipid Peroxidation ; Male ; Mannitol ; Midazolam ; Nitroglycerin ; Norepinephrine ; Propofol* ; Rabbits ; Reactive Oxygen Species* ; Relaxation ; Transducers ; Vasodilation

No abstract available.
Aneurysm, False* ; Embolization, Therapeutic* ; Hepatic Artery*

No abstract available.
Plasmapheresis* ; Postpartum Period* ; Pregnancy*

OBJECTIVES: From February 1995 to April 1998, those patients who had visited for evaluation of infertility, shown abnormal endometrial pattern on hysterosalpingography underwent resectoscopic operation. We evaluated about its therapeutic effect, recurrence rate of uterine adhesion and effectiveness of its assisted method. METHOD: We have reviewed 45 cases of intrauterine adhesion, classified as a central type, marginal type and multiple type. We used 26F resectoscope made in Storz for operation and inserted Lippes loop or pediatric foley catheter for prevention of readhesion. For promoting reepithelialization, conjugated estrogens(premarin) 5mg daily for 30 - 50 days were given and then 10mg of medroxyprogesterone acetate(provera) were added daily for the last 10 days. We evaluated the uterine cavity condition preoperatively and postoperatively by using hysterosalpingography. RESULT: In 45 cases, 41 cases were followed up postoperatively. 21 cases were markedly improved, 12 cases were improved and 8 cases were not improved or recurred on hysterosalpingography. In 41 cases, for prevention of readhesion 20 cases were used pediatric foley catheter and 5 cases(25%) were recurred. 21 cases were used Lippes loop and 3 cases(14%) were recurred. Pregnancy outcome was as follows;15 cases were pregnant and 10 cases delivered a viable infant, 3 cases aborted spontaneously, 1 case was ectopic pregnancy and laparoscopic salpingectomy was done, 1 case was ongoing pregnancy. CONCLUSION: This report suggests that resectoscopic operation is very effective in the treatment of intrauterine adhesion(therapeutic rate of 81%) and that the use of Lippes loop seems like to have the less recurrence rate than the use of pediatric foley catheter in prevention of postoperative readhesion, but more experience and further follow-up are necessary to obtain more detailed conclusions.
Catheters ; Female ; Follow-Up Studies ; Humans ; Hysterosalpingography ; Infant ; Infertility ; Medroxyprogesterone ; Pregnancy ; Pregnancy Outcome ; Pregnancy, Ectopic ; Recurrence ; Salpingectomy