No abstract available.
Behcet Syndrome*

No abstract available.
Behcet Syndrome*

Gas tamponade is sometimes necessary after vitrectomy. Accurate measurement of intraocular pressure(IOP) in gas-filled eye is important, but is hard to get in operating table, because of lack of a good measuring device. Schiotz tonometry is the only possible method, but it usually gives a lower value than real, because gas-filled eye has a greater compressibility. But if the Schiotz tonometry can give a consistant value in relation to the real value, one can assume a true IOP by simply converting the value, and it will help the vitrectomy surgeon. Vitrectomy with or without lensectomy were done in 7 pigmented rabbits, and fluidair exchange were done at the end of the surgery. Intraocular pressure was monitored by an air infusion system, and true IOP was measured by a transducer from the anterior chamber. Schiotz tonometry was done ar each 5mmHg IOP level, and the values were compared. Schiotz tonometry always gave a lower pressure, and the discrepancy seemed to be greater in aphakic eye, and when the heavier plunger weight were used. Conversion equation was suggested, and their reliability was discussed.
Anterior Chamber ; Intraocular Pressure* ; Manometry ; Operating Tables ; Rabbits ; Transducers ; Vitrectomy*

The patient was a 7 months old Korean girl, who was admitted to Department of Ophthalmology of the Seoul National University Hospital, with 6 months history of the left eyelid swelling and exophthalmos. Visual acuity and ocular movement were unaffected. Orbit CT revealed 1.5x.5 cm sized well circumscribed intraconal mass in the left retrobulbar space with pressure erosion of adjacent bone. At surgery, the mass was pinkish gray and firm, and was adherent to adjacent tissue. The whole mass could not be removed, and a local excision was done.

Advanced glycation end-product(AGE)is known as a factor causing diabetic retinopathy, but little is known about its effect on the function of outer blood-retinal barrier. To test whether AGE can increase the permeability of outer blood-retinal barrier, we injected glycated albumin into white rabbit eyes and observed the change of the fundus and of the outer blood-retinal barrier permeability. The rabbit retina in medullary ray was thickened in AGE-injected eyes. Intravenously injected microperoxidase, tracer molecule, was found in outer sensory retinal layer and outside of the retinal pigment epithelium in AGE-injected eyes. These results suggest that intraocularly injected AGE can increase the outer blood-retinal barrier permeability.
Blood-Retinal Barrier* ; Diabetic Retinopathy ; Permeability ; Retina ; Retinal Pigment Epithelium ; Retinaldehyde

A 10 years' old male patient was admitted to this hospital due to severe esodeviation of his right eye, which developed after Kronlein operation 11 months before. Esodeviation of 80 PD, right eye, was noted with abduction range of barely to the midline. Jensen procedure was performed, and the eye became orthophoric, with abduction range of 45 dergee.
Esotropia ; Humans ; Male ; Paralysis*

The 291 eyes of the 280 retinal detachment patients were analyzed for general state of the retinal detachment, and 261 eyes of 250 patients were analyzed for the result of surgery. About half (49.3%) of the patient were between 20~39 years of age, and 8.6% were bilateral. Men were affected more than women (71.7:28.3). Round holes were predominant (54.3%), then horse-shoe tears (23.1%). Most were located at superior temporal quadrant, but dialysis were predominant at inferior temporal quadrant. Most (68.4%) of the patient were myopic, and aphakic patients were 9.4%, and trauma were associated in 10.3% of cases. The overall success rate of rhegmatogenous retinal detachment was 74.0%. The kind, number of the holes showed no effect on the success rate, only giant tears showed poor success rate. The age showed no effect on the success rate, except the group below 10 years of age, which showed poor success rate. The good pre-op vision, the normal IOP, The short duration, and small localized detachment had favorable effect on success rate. The repetition of the operation, and aphakia showed unfavorable effect. The shorter the duration, the lower the degree of the myopia, and the better the pre-op vision, were the final vision better. The cryopexy wns less associated with complications than diathermy. The most frequent causes of failure were giant tear and MVR. If the tear was not detected, the prognosis was poor, and nonrhegmatogenous retinal detachment showed poor prognosis.
Aphakia ; Dialysis ; Diathermy ; Female ; Humans ; Male ; Myopia ; Prognosis ; Retinal Detachment* ; Retinaldehyde*

The results of diabetic vitrectomy on eyes with severe proliferative fibrovascular membranes are often disappointing, because of difficulties in removing the membranes. But we sometimes observe the regression of the proliferative fibrovascular membranes when the antero-posterior tractional force become released. Hence we compared the surgical prognosis of proliferative diabetic retmopathy according to the severity of proliferation and whether removal of antero-posterior vitreoretinal traction was complete or not. The results showed that the anatomic success rate and final visual acuities(VA) were significantly better in less-severe proliferation group(LSPG) than in severe prolif era tion group(SPG). In SPG, the anatomic success rate and VA tended to be better when we were able to remove the antero-posterior vitreoretinal adhesion completely whether the removal of preretinal membranes was complete or not. When complete removal of the diabetic fibrovascular membrane is difficult due to severe proliferation and broad adhesion, complete removal of anter-posterior traction only could be an alternative in diabetic vitrectomy.
Membranes ; Prognosis ; Traction ; Vitrectomy

This experiment was performed to demonstrate that the cell-mediated hypersensitivity plays an important role in the development of the so-called endophthalmitis phaooanaphylactica. Fifteen albino guinea pigs were immunized with sclubte proteins of bovine lens with complete Freund's adjuvant. The immunizations were repeated 4 times at 5 days intervals. 5 days after the last injection, the skin test was performed with soluble lens protein, and liquid paraffin was injected into the peritoneal cavity. 7 days after paraffin injection, the peritoneal exudate cells were harvested, and were allowed to migrate on agar with and without antigen according to Salvin- Niahio method. All of them shows positive skin reaction and significant inhibition of migration under the presence of the antigen.
Agar ; Animals ; Endophthalmitis ; Exudates and Transudates ; Freund's Adjuvant ; Guinea Pigs ; Hypersensitivity ; Immunization ; Mineral Oil ; Paraffin ; Peritoneal Cavity ; Skin ; Skin Tests ; Staphylococcal Protein A*

Effective dose of laser photocoagulation in proliferative diabetic retinopathy. We retrospectively studied 153 eyes of 106 patients to know correlation between the regression and the amount of retinal ablation, and to know clinical result after panretinal photocoagulation. Regression was observed in 100 eyes (65.4%), stationary status in 39 eyes (25.5%) and progression in 14 eyes (9.2%) in the 6 to 8 weeks following treatment. Stabilization was achieved in 98 eyes (64.1%) in the minimum follow-up of one year. Regression was observed in 78 eyes(79.6%) of low risk PDR versus 22 eyes (40.0%) of high risk PDR, and it was statistically significant (p=0.0001). The mean ablation area was 231.01+/-83.54 mm2. In high risk PDR, ablation area of eyes which were regressed was 279.33+/-111.39 mm2, compared to 220.42+/-91.61 mm2 which were not regressed(p=0.0337). In low risk PDR, there are no correlation between the ablation area and regression. Vision was decreased after photocoagulation 31 eyes(20.3%), and cystoid macular edema(CME) was the main cause of visual loss, however, the CME was not correlated with ablation area. Regression of new vessel was highly correlated with ablation area in high risk PDR.
Diabetic Retinopathy ; Follow-Up Studies ; Humans ; Light Coagulation* ; Retinaldehyde ; Retrospective Studies