Objective To investigate blood glucose,HbA1c and GA levels in patients with acute cerebral infarction.Methods 129 patients with acute cerebral infarction and 102 healthy persons were recruited.Blood glucose,HbA1c and GA levels were com-pared between acute infarction patients and healthy people.The correlation of blood glucose,HbA1c and GA with different degree of neurological deficits,number and sizes of infarct lesions and prognosis were explored.Results Fasting plasma glucose,HbA1c and GA levels in patients with acute cerebral infarction were significantly higher than in healthy people(P <0.05).GA and HbA1c levels were higher in patients with more severe degree of neurological deficit,larger infarct volume and poorer prognosis,and the differences were statistically significant (P <0.05).GA level was significantly higher in patients with multifocal infraction than pa-tients with single(P <0.05),however,there were no differences of HbA1c between the two groups.No significantly differences of fasting blood glucose were found among the patients classified with neurological deficit,number and sizes of infarct lesion and prog-nosis(P >0.05).Conclusion Blood glucose,HbA1c and GA levels were closely related with neurological deficit,severity and prog-nosis of acute cerebral infarction,thus determination of these indicators is of important clinical significance.