1.Recent advances in mechanism and treatment of fracture-related tension blister
Xiaojun CHEN ; Junfei GUO ; Huiyang JIA ; Chen WANG ; Jialiang GUO ; Xingui WANG ; Kuo ZHAO ; Zhiyong HOU ; Yingze ZHANG
Chinese Journal of Trauma 2021;37(9):848-854
The presence of tension blister often predicts severe soft tissue damage,which not only increases the risk of wound complications but also prolongs the surgical treatment time. However,the developed tension blister has been proposed as a potential decompressive approach for it may relieve the pressure of osteofascial compartment and improve the likelihood of relieving clinical symptoms,as well as avoid unnecessary surgery in cases of suspected osteofascial compartment syndrome. Recently,the osteofascial system has been increasingly recognized that associations were found between the tension blister and osteofascial self-release processing. Thus,the timing of blister occurrence and regression substantially influences physicians′ clinical decisions,making blister management as part of the treatment of fractures. In this review,the authors give an overview of the characteristics,mechanism,stress reduction effect,prevention,current treatment status and complications of the fracture-related tension blister,hoping to help orthopedic physicians understand and treat the tensile blister.
2.Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver.
Bingbing HE ; Wenbo PENG ; Jia HUANG ; Hang ZHANG ; Yingsi ZHOU ; Xiali YANG ; Jing LIU ; Zhijie LI ; Chunlong XU ; Mingxing XUE ; Hui YANG ; Pengyu HUANG
Protein & Cell 2020;11(7):518-524