1.DNA Damage in Hippocampal Cells of Rats Induced by Exposure to 1800 MHz Electromagnetic Irradiation
Huixin WU ; Ping LIU ; Chuntao HUANG
Journal of Environment and Health 1992;0(05):-
Objective To study the DNA damage in hippocampal cells of rats induced by 1 800 MHz electromagnetic irradiation. Methods Wistar rats were randomly divided into four groups, 2 exposed groups and 2 controls. The experimental subjects were exposed to the 1 800 MHz (continuous wave, CW) electromagnetic fields for 21days (12 h/d), the power densities were 0.5 mW/cm2 and 1.0 mW/cm2, meanwhile, sham-control exposures were carried out, the DNA damage was examined by Comet assay. Results The tailed rate and the tail area of the hippocampal cells in 1.0 mW/cm2 group was higher or larger than those in the control and 0.5 mW/cm2 groups(P
2.Role of epidermal growth factor in ocular diseases
Huixin SONG ; Jianfeng WU ; Hongsheng BI
Recent Advances in Ophthalmology 2017;37(5):484-487
Epidermal growth factor (EGF) is a multifunctional growth factor,which is widely expressed in most ocular tissues including cornea,retina and sclera.It may regulate the growth and proliferation of various ocular cells with the interaction of epidermal growth factor receptor in vitro or in vivo.This article reviews the role of EGF in pathological and physiological processes of ocular diseases,including corneal injury,retinal proliferative diseases,myopia,pterygium,glaucoma,cataract,and eye tumors.
3.Intravenous Immune Globulin Therapy For 14 Cases of Rh Hemolytic Disease of Newborn
Huixin WANG ; Mingchang WU ; Caiyun YANG
Chinese Journal of Perinatal Medicine 1998;0(01):-
Objective To observe the effect of intravenous immune globulin (IVIG) therapy on newborn infants of Rh hemolytic disease. Methods IVIG group (n=14) received conventional treatments including albumin administration and phototherapy with additional IVIG therapy at a daily dose of 400 mg/kg given for 1~5 consecutive days,and control group (n=16) only received conventional treatments. Effects were compared between the two groups. Result There were 25 patients with hyperbilirubinemia caused by Rh hemolytic disease received exchange transfusions. IVIG was infused in 12 cases,100% of them had the total serum bilirubin level dropped down during the treatment before the exchange transfusions, vs 5 (38%) of 13 cases in control group (P
4.The Therapeutic Effects of Different High Doses of IVIG on 48 Newborn Infants with Severe ABO Hemolytic Disease
Caiyun YANG ; Mingchang WU ; Huixin WANG
Chinese Journal of Perinatal Medicine 1998;0(01):-
Objective To observe the therapeutic effects of intravenous immunoglobulin (IVIG) between the higher dose (1 g/kg) and the lower dose (400 mg/(kg?d)1~3 d) for severe ABO hemolytic disease of newborn. Methods 48 term infants with severe hyperbilirubinemia receiving IVIG were divided into 2 groups. 24 cases in group A with higher dose, while 24 cases in group B with lower dose, another 20 cases without IVIG in the control group C. Phototherapy were used concomitantly for all infants in these 3 groups. The days of life on admission, the days of jaundice appearance, and the peak of serum bilirubin concentration (TB) in each group were macthed. The theraputic effects in TB reduced between each group were compared. Results The infants admitted on the 1st day of life in group A,B,and C were 11, 11, and 8 cases respectively, the range of TB(MTB) in the 3 groups were 230~237?mol/L (13.5~13.9 mg/dl). After treatment, the MTB declined to 203?mol/L (12 mg/dl) in group A within 24hrs, vs 285~316 ?mol/L (17~18 mg/dl) in group B and C,P
5.Effects of Pregnancy Exposure to 1800 MHz Electromagnetic Irradiation on Hippocampus Ultrastructure of Offspring Rats
Yuan ZHANG ; Huixin WU ; Hongling LI
Journal of Environment and Health 2007;0(09):-
Objective To study effects of 1 800 MHz electromagnetic field exposure in pregnancy on the ultrastructure of the hippocampus of offspring rats. Methods Ninety Wistar rats(female and male was 2:1) were mated,and the pregnant rats were exposed to 1 800 MHz microwave field with power density of 0.5 mW/cm2 or 1.0 mW /cm2,12 h/d,for 21 consecutive days,the rats in the control group received dummy exposure. Three rats aged 3 days and 72 days were selected from groups for ultrastructure observation of hippocampus. Results No significant pathological changes were observed in nerve cells and capillary vessels in the hippocampus. Conclusion The results of the present paper indicate that pregnancy exposure to 1 800 MHz electromagnetic field,may not lead to abnormal ultrastructure changes in hippocampus of offspring rats
6.Effect of Liu's Massage Technique on Teenagers with Cervical Vertebra Disease
Yan HONG ; Fenglin ZHAO ; Huixin WU
Chinese Journal of Rehabilitation Theory and Practice 2008;14(6):570-571
Objective To observe the effect of Liu's massage technique on teenagers with cervical vertebra disease.Methods 65 teenagers with cervical vertebra disease were divided into the trial group (n=35) and control group (n=30) treated with routine physical therapy and cervical vertebra disease gymnastics, but cases in the trial group were added with treatment of Liu's massage technique. All cases of two groups were evaluated with Clinical Assessment Scale for Cervical Spondylosis (CASCS) before and after treatment.Results After treatment, the CASCS scores of all cases improved significantly ( P<0.01), but the effect of the trial group was significantly superior to that of the control group ( P<0.01).Conclusion Liu's massage technique is effective on cervical vertebra disease of teenagers.
7.Expression of PDGF-B in renal cortex of diabetic rat
Chunhua SUI ; Wanling WU ; Jinyang HONG ; Huixin ZHANG
Chinese Journal of Endocrinology and Metabolism 1986;0(04):-
Expression of platelet-derived growth factor (PDGF)-B mRNA was measured by semi-quantitative RT-PCR in renal cortex of diabetic and control Wistar rats. The expression of PDGF-B mRNA in renal cortex of diabetic rats was 2.5-fold of normal rats, suggesting that PDGF-B seems to play a role in diabetic nephro-pathy.
9.Predictive value of plasma N-terminal-pro-brain natriuretic peptide in weaning patients from mechanical ventilation
Shangfeng LI ; Jingyi WU ; Yaru ZOU ; Huixin LIANG ; Jianjing TONG ; Jing YE ; Yiming LU
Chinese Journal of Emergency Medicine 2016;25(3):334-337
Objective To evaluate the predictive value of N-terminal-pro-brain natriuretic peptide (NT-proBNP) in weaning patients from mechanical ventilation (MV).Methods Data of 42 patients supported with MV in intensive care unit (ICU) admitted to the Rui Jin Hospital from January through December in 2014 were retrospectively analyzed,and the causes for MV were recorded.According to the outcomes of weaning from MV after 48 hours,the patients were divided into two groups namely success group and failure group.Comparisons of fluid balance in 72 hours before spontaneous breathing trial (SBT),and comparisons of NT-proBNP1 levels at admission,NT-proBNP2 levels before SBT,NT-proBNP3 levels after 48 hours after SBT between two groups were carried out.And the receiver operating characteristic (ROC) curve for predicting weaning rate was plotted to find the optimal cut-off point of NT-proBNP2.Results In the total of 42 patients,there were 27 cases in success group and 15 cases in failure group.There were not statistically differences of NT-proBNP1 levels between success group and failure group (P =0.121).However,the NT-proBNP2 levels and NT-proBNP3 levels in failure group were significantly higher than those in success group (P =0.01,0.003).The area under curve (AUC) of the ROC curve of NT-proBNP2 levels to predict the failure of weaning was 0.862 (95% CI:0.753-0.971).When the optimal cut-off point of NT-proBNP2 was 715.5 pg/mL,the sensitivity and specificity were 93.3% and 74.1%,respectively.Conclusion The NT-proBNP2 levels before SBT have predictive value in weaning rate,and it can be used as one of the screening indicators for weaning.
10.Analysis and Countermeasures of Medical Student' s Cognition of Death
Chinese Medical Ethics 2017;30(10):1300-1304
Objective: To understand the cognition of death among medical students and put forward some countermeasures .Methods:Stratified sampling was used to select 730 medical students in Fujian .A self -de-signed cognition of death questionnaire and Fear of Death Scale ( FODS) were adopted to conduct the survey .Re-sults:The general cognition of death among medical students was normal (84.8%).Fear of death, either towards themselves or their families , was significantly different in participants ' gender (χ2 =29 .552 , P<0 .001 ) , major (χ2 =6.343,P=0.042), and grade (χ2 =13.979, P=0.030).Thinking of death towards themselves was signif-icantly different in participants' living places (χ2 =10.110, P=0.006), bereavement experience (χ2 =7.353, P=0 .025 ) , religion (χ2 =16 .307 , P=0 .003 ) .Meanwhile , statistical significances were found in the thinking of death towards their families among different bereavement experience (χ2 =14.962, P=0.001) and religion (χ2 =12.359, P=0.015).Grade and religion greatly affected the attitudes towards death of families , while bereavement experience and grade had the great impact on the attitudes towards death of respondent themselves .In the fear of death for participant themselves and their families , gender made the biggest difference .Conclusion: Medical students have a high level of death anxiety .Medical universities and colleges should strengthen death education in medical students and improve its course system in the future .